| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jane Yip, Jean Jacques Soghomonian, Gene J Blat. Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study. Autism research : official journal of the International Society for Autism Research. vol 2. issue 1. 2009-07-13. PMID:19358307. |
the laterally positioned dentate nuclei lie in a key position in the cerebellum to receive input from purkinje cells in the lateral cerebellar hemisphere participating in both motor and cognitive functions. |
2009-07-13 |
2023-08-12 |
Not clear |
| R X Moldrich, J Lainé, A Visel, P M Beart, J Laffaire, J Rossier, M-C Potie. Transmembrane protein 50b (C21orf4), a candidate for Down syndrome neurophenotypes, encodes an intracellular membrane protein expressed in the rodent brain. Neuroscience. vol 154. issue 4. 2009-06-29. PMID:18541381. |
in adult mouse cerebellum sections, tmem50b immunoreactivity was found in purkinje and golgi cell somata and in bergmann glial processes. |
2009-06-29 |
2023-08-12 |
mouse |
| Tiina Keisala, Anna Minasyan, Yan-Ru Lou, Jing Zou, Allan V Kalueff, Ilmari Pyykkö, Pentti Tuohima. Premature aging in vitamin D receptor mutant mice. The Journal of steroid biochemistry and molecular biology. vol 115. issue 3-5. 2009-06-24. PMID:19500727. |
there was no difference either in the structure of cerebellum or in the number of purkinje cells. |
2009-06-24 |
2023-08-12 |
mouse |
| Young-Ki Bae, Shuichi Kani, Takashi Shimizu, Koji Tanabe, Hideaki Nojima, Yukiko Kimura, Shin-ichi Higashijima, Masahiko Hib. Anatomy of zebrafish cerebellum and screen for mutations affecting its development. Developmental biology. vol 330. issue 2. 2009-06-12. PMID:19371731. |
using anti-parvalbumin7 and vglut1 antibodies to label purkinje cells and granule cell axons, respectively, we screened for mutations affecting cerebellar neuronal development and the formation of neural tracts. |
2009-06-12 |
2023-08-12 |
zebrafish |
| Hui Xiong, Kun Xia, Benshang Li, Guoping Zhao, Zhuohua Zhan. KChIP1: a potential modulator to GABAergic system. Acta biochimica et biophysica Sinica. vol 41. issue 4. 2009-06-09. PMID:19352544. |
kchip1 is expressed predominantly in brain, with relative abundance in purkinje cells of cerebellum, the reticular thalamic nuclei, the medial habenular nuclei, the hippocampus, and striatum. |
2009-06-09 |
2023-08-12 |
mouse |
| Yei-Tsung Chen, Loretta L Collins, Shu-Shi Chang, Chawnshang Chan. The roles of testicular orphan nuclear receptor 4 (TR4) in cerebellar development. Cerebellum (London, England). vol 7. issue 1. 2009-06-08. PMID:18418664. |
in addition, abnormal development of purkinje cells was observed in the postnatal tr4(-/-) cerebellum, as indicated by aberrant dendritic arborization. |
2009-06-08 |
2023-08-12 |
mouse |
| Toru Yoshihara, Kazushi Sugihara, Yasuhiko Kizuka, Shogo Oka, Masahide Asan. Learning/memory impairment and reduced expression of the HNK-1 carbohydrate in beta4-galactosyltransferase-II-deficient mice. The Journal of biological chemistry. vol 284. issue 18. 2009-06-08. PMID:19265195. |
histological examination showed abnormal alignment and reduced number of purkinje cells in the cerebellum of beta4galt-ii(-/-) mice. |
2009-06-08 |
2023-08-12 |
mouse |
| Takatoshi Iijima, Kyoichi Emi, Michisuke Yuzak. Activity-dependent repression of Cbln1 expression: mechanism for developmental and homeostatic regulation of synapses in the cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 17. 2009-06-03. PMID:19403810. |
cbln1, which belongs to the c1q/tumor necrosis factor superfamily, is released from cerebellar granule cells and plays a crucial role in forming and maintaining excitatory synapses between parallel fibers (pfs; axons of granule cells) and purkinje cells not only during development but also in the adult cerebellum. |
2009-06-03 |
2023-08-12 |
Not clear |
| Yusuke Takatsuru, Masae Iino, Kohichi Tanaka, Seiji Ozaw. Contribution of glutamate transporter GLT-1 to removal of synaptically released glutamate at climbing fiber-Purkinje cell synapses. Neuroscience letters. vol 420. issue 1. 2009-06-02. PMID:17513050. |
in the cerebellum, glial glutamate transporters, glast and glt-1, are co-localized in the processes of bergmann glia wrapping excitatory synapses on purkinje cells (pcs). |
2009-06-02 |
2023-08-12 |
mouse |
| Anita Wiersema, Freark Dijk, Bert Dontje, Johannes J van der Want, Gerald de Haa. Cerebellar heterokaryon formation increases with age and after irradiation. Stem cell research. vol 1. issue 2. 2009-05-27. PMID:19383395. |
in addition, purkinje heterokaryons occur in increased frequencies in the cerebellum of normal, unperturbed, aged mice compared to young animals. |
2009-05-27 |
2023-08-12 |
mouse |
| Anita Wiersema, Freark Dijk, Bert Dontje, Johannes J van der Want, Gerald de Haa. Cerebellar heterokaryon formation increases with age and after irradiation. Stem cell research. vol 1. issue 2. 2009-05-27. PMID:19383395. |
our data suggest that age- and/or irradiation-induced dysfunctioning of purkinje cells in the cerebellum is required for cell fusion. |
2009-05-27 |
2023-08-12 |
mouse |
| U Frey, U Egert, F Heer, S Hafizovic, A Hierleman. Microelectronic system for high-resolution mapping of extracellular electric fields applied to brain slices. Biosensors & bioelectronics. vol 24. issue 7. 2009-05-26. PMID:19157842. |
to illustrate the device performance, extracellular potentials of purkinje cells (pcs) in acute slices of the cerebellum have been analyzed. |
2009-05-26 |
2023-08-12 |
Not clear |
| Jill M Weimer, Jared W Benedict, Amanda L Getty, Charlie C Pontikis, Ming J Lim, Jonathan D Cooper, David A Pearc. Cerebellar defects in a mouse model of juvenile neuronal ceroid lipofuscinosis. Brain research. vol 1266. 2009-05-26. PMID:19230832. |
additionally, there is a loss of purkinje cells (pc) in regions of robust bergmann glia activation in cln3(-/-) mice and human jncl post-mortem cerebellum. |
2009-05-26 |
2023-08-12 |
mouse |
| K Seidel, Rai De Vos, L Derksen, P Bauer, O Riess, W den Dunnen, T Deller, G Hageman, U Rü. Widespread thalamic and cerebellar degeneration in a patient with a complicated hereditary spastic paraplegia (HSP). Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 191. issue 2. 2009-05-20. PMID:19230631. |
this pathoanatomical investigation revealed in addition to loss of layer v betz pyramidal cells in the primary motor cortex, widespread cerebellar neurodegeneration (i.e., loss of purkinje cells and neuronal loss in the deep cerebellar nuclei), extensive and severe neuronal loss in a large number of thalamic nuclei, involvement of some brainstem nuclei, as well as damage to descending (i.e., lateral and ventral corticospinal tracts) and ascending (i.e., dorsal and ventral spinocerebellar tracts, gracile fascicle) fiber tracts. |
2009-05-20 |
2023-08-12 |
Not clear |
| Kazuhiko Sawada, Abul Kalam Azad, Hiromi Sakata-Haga, Nam-Seob Lee, Young-Gil Jeong, Yoshihiro Fuku. Striking pattern of Purkinje cell loss in cerebellum of an ataxic mutant mouse, tottering. Acta neurobiologiae experimentalis. vol 69. issue 1. 2009-05-18. PMID:19325647. |
quite consistent with the histopathological observations, quantitation of the density of calbindin d-28k and zebrin ii immunopositive purkinje cells in the tottering cerebellum revealed that the purkinje cells were selectively lost in the zebrin ii immunonegative compartments of the lobules i and ii but in the zebrin ii immunopositive compartments in the lobule ix. |
2009-05-18 |
2023-08-12 |
mouse |
| Hirokazu Hira. Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors. Cerebellum (London, England). vol 7. issue 3. 2009-05-15. PMID:18418690. |
expression of a foreign gene in cerebellar purkinje cells in vivo is a powerful method for exploring the pathophysiology of the cerebellum. |
2009-05-15 |
2023-08-12 |
mouse |
| Yoshio Ikeda, Randy S Daughters, Laura P W Ranu. Bidirectional expression of the SCA8 expansion mutation: one mutation, two genes. Cerebellum (London, England). vol 7. issue 2. 2009-05-15. PMID:18418692. |
these mice show a loss of cerebellar gabaergic inhibition and, similar to human patients, have 1c2-positive intranuclear inclusions in purkinje cells and other neurons. |
2009-05-15 |
2023-08-12 |
mouse |
| Asher J Albertson, Heather Talbott, Qi Wang, Dane Jensen, Donal C Skinne. The gonadotropin-releasing hormone type I receptor is expressed in the mouse cerebellum. Cerebellum (London, England). vol 7. issue 3. 2009-05-15. PMID:18592335. |
here, we describe the presence of immunoreactive gnrh receptors in the purkinje cells of the mammalian cerebellum for the first time. |
2009-05-15 |
2023-08-12 |
mouse |
| Luz Delgado, Oliver Schmachtenber. Immunohistochemical localization of GABA, GAD65, and the receptor subunits GABAAalpha1 and GABAB1 in the zebrafish cerebellum. Cerebellum (London, England). vol 7. issue 3. 2009-05-15. PMID:18633686. |
gaba and gad65 presented a similar expression pattern that comprised the molecular layer, purkinje cells and groups of presumed golgi cells in the granular layer, both in the cerebellar corpus and valve. |
2009-05-15 |
2023-08-12 |
zebrafish |
| De-lai Qiu, Thomas Knöpfe. Presynaptically expressed long-term depression at cerebellar parallel fiber synapses. Pflugers Archiv : European journal of physiology. vol 457. issue 4. 2009-05-05. PMID:18663469. |
plasticity at synapses between parallel fiber (pf) and purkinje neurons (pn) is widely accepted as a cellular model for certain forms of cerebellar learning. |
2009-05-05 |
2023-08-12 |
Not clear |