| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alison Hamilton, Christian Hölsche. Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. Neuroreport. vol 20. issue 13. 2009-11-10. PMID:19617854. |
in the cerebellum, only purkinje neurons express the receptor. |
2009-11-10 |
2023-08-12 |
Not clear |
| Jakob Jankowski, Andreas Miething, Karl Schilling, Stephan L Baade. Physiological purkinje cell death is spatiotemporally organized in the developing mouse cerebellum. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19238501. |
here, we document that during normal cerebellar development, dying purkinje cells were highly localized within the vermal midline and in a lobule specific, parasagittal pattern along the whole mediolateral axis. |
2009-11-09 |
2023-08-12 |
mouse |
| Emmanuelle Bitoun, Kay E Davie. The robotic mouse: understanding the role of AF4, a cofactor of transcriptional elongation and chromatin remodelling, in purkinje cell function. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19340490. |
we have previously established that the mutated protein af4, which is a member of the af4/laf4/fmr2 (alf) family of transcription cofactors frequently translocated in childhood leukaemia, undergoes slower proteasomal turnover through the ubiquitin pathway and abnormally accumulates in purkinje cells of the cerebellum. |
2009-11-09 |
2023-08-12 |
mouse |
| Stefan Glasauer, Thomas Stephan, Roger Kalla, Sarah Marti, Dominik Strauman. Up-down asymmetry of cerebellar activation during vertical pursuit eye movements. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19415407. |
animal experiments have demonstrated that the vast majority of vertical gaze-velocity purkinje cells in the cerebellar floccular lobe, whose firing rate is modulated during vertical smooth pursuit eye movements, show a preference for downward pursuit. |
2009-11-09 |
2023-08-12 |
Not clear |
| Kejian Chen, Donald A Godfrey, Omer Ilyas, Jiansong Xu, Todd W Presto. Cerebellum-related characteristics of Scn8a-mutant mice. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19424768. |
density of gaba-like immunoreactivity is decreased in purkinje somata and regions of termination in deep cerebellar and vestibular nuclei of scn8a ( medj ) mice, but measured gaba concentration is not significantly reduced in microdissected samples of these regions. |
2009-11-09 |
2023-08-12 |
mouse |
| Krystal L Parker, Svitlana Zbarska, Andrew J Carrel, Vlastislav Brach. Blocking GABAA neurotransmission in the interposed nuclei: effects on conditioned and unconditioned eyeblinks. Brain research. vol 1292. 2009-11-06. PMID:19635470. |
the in, which represent the sole output of the intermediate cerebellum, receive massive gabaergic input from purkinje cells of the cerebellar cortex and are thought to contribute to the acquisition and performance of classically conditioned eyeblinks. |
2009-11-06 |
2023-08-12 |
Not clear |
| Pedro M O Pedroso, Raquel Von Hohendorf, Luiz G S de Oliveira, Milene Schmitz, Cláudio E F da Cruz, David Driemeie. Sida carpinifolia (Malvaceae) poisoning in fallow deer (Dama dama). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. vol 40. issue 3. 2009-10-22. PMID:19746879. |
the cytoplasm of multiple cells of the cerebellum, especially the purkinje cells, stained with the lectins concanavalia ensiformis, triticum vulgaris, and succinylated triticum vulgaris. |
2009-10-22 |
2023-08-12 |
cattle |
| Gary J Stephen. G-protein-coupled-receptor-mediated presynaptic inhibition in the cerebellum. Trends in pharmacological sciences. vol 30. issue 8. 2009-10-21. PMID:19632729. |
in the cerebellum, neurotransmitter release onto purkinje cells occurs by ap-dependent and ap-independent pathways. |
2009-10-21 |
2023-08-12 |
human |
| Xuejing Li, David R Serwanski, Celia P Miralles, Koh-Ichi Nagata, Angel L De Bla. Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity. The Journal of biological chemistry. vol 284. issue 25. 2009-10-20. PMID:19380581. |
septin 11 is expressed throughout the brain, being particularly high in the spiny branchlets of the purkinje cells in the molecular layer of cerebellum and in the olfactory bulb. |
2009-10-20 |
2023-08-12 |
rat |
| M Yuzak. New (but old) molecules regulating synapse integrity and plasticity: Cbln1 and the delta2 glutamate receptor. Neuroscience. vol 162. issue 3. 2009-10-19. PMID:19124061. |
the delta2 glutamate receptor (glurdelta2) is predominantly expressed in cerebellar purkinje cells and plays crucial roles in cerebellar functions: glurdelta2-null mice display ataxia and impaired motor learning. |
2009-10-19 |
2023-08-12 |
mouse |
| M Yuzak. New (but old) molecules regulating synapse integrity and plasticity: Cbln1 and the delta2 glutamate receptor. Neuroscience. vol 162. issue 3. 2009-10-19. PMID:19124061. |
thus, we propose that cbln1, which is released from granule cells, and glurdelta2, which is predominantly expressed in purkinje cells, are involved in a common signaling pathway crucial for synapse formation/maintenance and plasticity in the cerebellum. |
2009-10-19 |
2023-08-12 |
mouse |
| S Nakanish. Genetic manipulation study of information processing in the cerebellum. Neuroscience. vol 162. issue 3. 2009-10-19. PMID:19344639. |
a novel technique termed reversible neurotransmission blocking (rnb) was genetically established, in which granule cell transmission to purkinje cells was selectively and reversibly blocked in the mouse cerebellar circuitry. |
2009-10-19 |
2023-08-12 |
mouse |
| Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, Yasushi Tamura, Masahiro Fukaya, Thomas W Kensler, Miho Iijima, Hiromi Sesak. The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice. The Journal of cell biology. vol 186. issue 6. 2009-10-15. PMID:19752021. |
brain-specific drp1 ablation caused developmental defects of the cerebellum in which purkinje cells contained few giant mitochondria instead of the many short tubular mitochondria observed in control cells. |
2009-10-15 |
2023-08-12 |
mouse |
| Wiljan J A J Hendriks, Gönül Dilaver, Yvet E Noordman, Berry Kremer, Jack A M Franse. PTPRR protein tyrosine phosphatase isoforms and locomotion of vesicles and mice. Cerebellum (London, England). vol 8. issue 2. 2009-09-30. PMID:19137382. |
during cerebellar maturation, ptpbr7 expression in developing purkinje cells ceases and is replaced by ptp-sl expression in the mature purkinje cells. |
2009-09-30 |
2023-08-12 |
mouse |
| S-H Chung, H Marzban, R Hawke. Compartmentation of the cerebellar nuclei of the mouse. Neuroscience. vol 161. issue 1. 2009-09-21. PMID:19306913. |
the cerebellar nuclei integrate inhibitory input from purkinje cells with excitatory input from mossy and climbing fiber collaterals and are the sole cerebellar output. |
2009-09-21 |
2023-08-12 |
mouse |
| Hana Ros, Robert N S Sachdev, Yuguo Yu, Nenad Sestan, David A McCormic. Neocortical networks entrain neuronal circuits in cerebellar cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 33. 2009-09-11. PMID:19692605. |
we provide evidence that the cerebellar slow oscillation results in part from the activation of granule, golgi, and purkinje neurons. |
2009-09-11 |
2023-08-12 |
Not clear |
| Takayuki Uchida, Atsushi Baba, F Javier Pérez-Martínez, Terumasa Hibi, Takaki Miyata, Juan M Luque, Kazunori Nakajima, Mitsuharu Hattor. Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 34. 2009-09-10. PMID:19710317. |
in the wild-type cerebellum, functional reelin receptors are mainly present in the cerebellar ventricular zone but scarcely expressed by purkinje cells that have migrated out of it. |
2009-09-10 |
2023-08-12 |
Not clear |
| Hadi S Zanjani, Rebecca McFarland, Pauline Cavelier, Andrei Blokhin, Vanessa Gautheron, Carole Levenes, Linda L Bambrick, Jean Mariani, Michael W Voge. Death and survival of heterozygous Lurcher Purkinje cells in vitro. Developmental neurobiology. vol 69. issue 8. 2009-09-09. PMID:19294643. |
to determine if the glurdelta2(+/lc) purkinje cell phenotype is recapitulated in vitro, +/+, and +/lc purkinje cells from postnatal day 0 pups were grown in either isolated cell or cerebellar slice cultures. |
2009-09-09 |
2023-08-12 |
Not clear |
| Peer Wulff, Martijn Schonewille, Massimiliano Renzi, Laura Viltono, Marco Sassoè-Pognetto, Aleksandra Badura, Zhenyu Gao, Freek E Hoebeek, Stijn van Dorp, William Wisden, Mark Farrant, Chris I De Zeeu. Synaptic inhibition of Purkinje cells mediates consolidation of vestibulo-cerebellar motor learning. Nature neuroscience. vol 12. issue 8. 2009-09-09. PMID:19578381. |
although feedforward inhibition onto purkinje cells was first documented 40 years ago, we understand little of how inhibitory interneurons contribute to cerebellar function in behaving animals. |
2009-09-09 |
2023-08-12 |
mouse |
| J Paul Simons, Raya Al-Shawi, Shane Minogue, Mark G Waugh, Claudia Wiedemann, Stylianos Evangelou, Andrzej Loesch, Talvinder S Sihra, Rosalind King, Thomas T Warner, J Justin Hsua. Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axons. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 28. 2009-09-09. PMID:19581584. |
histological analysis of aged pi4k2a(gt/gt) animals revealed lipofuscin-like deposition and gliosis in the cerebellum, and loss of purkinje cells. |
2009-09-09 |
2023-08-12 |
mouse |