| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ghazal Banisadr, Romain-Daniel Gosselin, Patricia Mechighel, Patrick Kitabgi, William Rostène, Stéphane Mélik Parsadaniant. Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides. The Journal of comparative neurology. vol 489. issue 3. 2008-03-26. PMID:16025454. |
neuronal expression of mcp-1/ccl2 is mainly found in the cerebral cortex, globus pallidus, hippocampus, paraventricular and supraoptic hypothalamic nuclei, lateral hypothalamus, substantia nigra, facial nuclei, motor and spinal trigeminal nuclei, and gigantocellular reticular nucleus and in purkinje cells in the cerebellum. |
2008-03-26 |
2023-08-12 |
rat |
| Xin Wang, Bagirathy Nadarajah, Andrew C Robinson, Barry W McColl, Jia-Wei Jin, Federico Dajas-Bailador, Raymond P Boot-Handford, Cathy Tournie. Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death. Molecular and cellular biology. vol 27. issue 22. 2008-03-26. PMID:17875933. |
these defects resulted in the misalignment of the purkinje cells in the cerebellum and delayed radial migration in the cerebral cortex. |
2008-03-26 |
2023-08-12 |
mouse |
| Nicolas Arbez, Vanessa Gautheron, Bernard Brugg, Jean Mariani, Catherine Rovir. Beta-amyloid(1-42) induces a reduction in the parallel fiber responses of Purkinje cells: possible involvement of pro-inflammatory processes. Experimental gerontology. vol 42. issue 10. 2008-03-21. PMID:17596899. |
using the patch-clamp technique we have studied the contribution of early pro-inflammatory processes to the acute effects of 1 microm abeta(1-42) on the parallel fiber epsc (pf-epsc) of purkinje cells in cerebellar slices. |
2008-03-21 |
2023-08-12 |
Not clear |
| Alexandra Moers, Alexander Nürnberg, Sandra Goebbels, Nina Wettschureck, Stefan Offermann. Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices. Molecular and cellular biology. vol 28. issue 5. 2008-03-17. PMID:18086886. |
here we show that conditional ablation of the genes encoding the alpha-subunits of g(12) and g(13) in the nervous system results in neuronal ectopia of the cerebral and cerebellar cortices due to overmigration of cortical plate neurons and cerebellar purkinje cells, respectively. |
2008-03-17 |
2023-08-12 |
mouse |
| Sylvie Bretin, Sophie Reibel, Emmanuelle Charrier, Marion Maus-Moatti, Nathalie Auvergnon, Anne Thevenoux, Jacques Glowinski, Véronique Rogemond, Joël Prémont, Jérôme Honnorat, Christian Gauch. Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain. The Journal of comparative neurology. vol 486. issue 1. 2008-03-13. PMID:15834957. |
in brain sections of adult mouse, crmp1, crmp2b, and crmp5 were located predominantly in dendrites of specific neuronal populations, such as cortical pyramidal neurons, hippocampal ca1 pyramidal cells, or purkinje cerebellar cells. |
2008-03-13 |
2023-08-12 |
mouse |
| Sylvie Bretin, Sophie Reibel, Emmanuelle Charrier, Marion Maus-Moatti, Nathalie Auvergnon, Anne Thevenoux, Jacques Glowinski, Véronique Rogemond, Joël Prémont, Jérôme Honnorat, Christian Gauch. Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain. The Journal of comparative neurology. vol 486. issue 1. 2008-03-13. PMID:15834957. |
in cultures of cortical neurons, crmp1, crmp2a, crmp2b, and crmp5 were equally distributed throughout cell bodies, axons, or dendrites of neurons, whereas crmp2a and crmp5 were completely absent from purkinje cerebellar cells in 12-day-old animals. |
2008-03-13 |
2023-08-12 |
mouse |
| Xiu R Lowe, Xiaochen Lu, Francesco Marchetti, Andrew J Wyrobe. The expression of Troponin T1 gene is induced by ketamine in adult mouse brain. Brain research. vol 1174. 2008-03-10. PMID:17850769. |
tnnt1 expression was induced in the granule layer of the hippocampus, amygdala, hypothalamus, purkinje cells of cerebellum (p<0.0001), and cerebral cortex. |
2008-03-10 |
2023-08-12 |
mouse |
| Murat Cetin Ragbetli, Birsen Ozyurt, Huseyin Aslan, Ersan Odaci, Alpaslan Gokcimen, Bunyamin Sahin, Suleyman Kapla. Effect of prenatal exposure to diclofenac sodium on Purkinje cell numbers in rat cerebellum: a stereological study. Brain research. vol 1174. 2008-03-10. PMID:17868656. |
in this study, we investigated the total number of purkinje cells of the cerebellum in a control group and in a ds-treated group of male rats using a stereological method. |
2008-03-10 |
2023-08-12 |
rat |
| Murat Cetin Ragbetli, Birsen Ozyurt, Huseyin Aslan, Ersan Odaci, Alpaslan Gokcimen, Bunyamin Sahin, Suleyman Kapla. Effect of prenatal exposure to diclofenac sodium on Purkinje cell numbers in rat cerebellum: a stereological study. Brain research. vol 1174. 2008-03-10. PMID:17868656. |
these results suggest that the purkinje cells of a developing cerebellum may be affected by administration of ds during the prenatal period. |
2008-03-10 |
2023-08-12 |
rat |
| M A Erickson, M Haburćák, L Smukler, K Dunla. Altered functional expression of Purkinje cell calcium channels precedes motor dysfunction in tottering mice. Neuroscience. vol 150. issue 3. 2008-03-10. PMID:18023294. |
the aberrant motor behaviors have been linked to cerebellar dysfunction, and adult purkinje cells (pcs) of tottering mice exhibit calcium-dependent changes in gene transcription suggestive of altered calcium homeostasis. |
2008-03-10 |
2023-08-12 |
mouse |
| Yizhe Sun, Donald A Godfrey, Kejian Chen, Leslie K Sprunger, Allan M Rubi. Comparison of gamma-aminobutyrate receptors in the medial vestibular nucleus of control and Scn8a mutant mice. Brain research. vol 1186. 2008-03-04. PMID:17999925. |
the purkinje cells of the cerebellum provide inhibitory input to vestibular nucleus neurons, with gamma-aminobutyrate (gaba) as neurotransmitter. |
2008-03-04 |
2023-08-12 |
mouse |
| Erica L Carpenter, Barbara A Vance, Rachel S Klein, Alfredo Voloschin, Josep Dalmau, Robert H Vonderheid. Functional analysis of CD8+ T cell responses to the onconeural self protein cdr2 in patients with paraneoplastic cerebellar degeneration. Journal of neuroimmunology. vol 193. issue 1-2. 2008-03-04. PMID:18053582. |
paraneoplastic cerebellar degeneration (pcd) is linked to an immune response against cerebellar degeneration related antigen 2 (cdr2) co-expressed in tumor and purkinje neurons. |
2008-03-04 |
2023-08-12 |
human |
| Joaquín Martí, M C Santa-Cruz, Shirley A Bayer, Bernardino Ghetti, José P Hervá. Purkinje cell age-distribution in fissures and in foliar crowns: a comparative study in the weaver cerebellum. Brain structure & function. vol 212. issue 3-4. 2008-02-29. PMID:17899183. |
generation and settling of purkinje cells (pcs) are investigated in the weaver mouse cerebellum in order to determine possible relationships with the fissuration pattern. |
2008-02-29 |
2023-08-12 |
mouse |
| Edward Zagha, Eric J Lang, Bernardo Rud. Kv3.3 channels at the Purkinje cell soma are necessary for generation of the classical complex spike waveform. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256249. |
voltage-gated potassium channel subunit kv3.3 is prominently expressed in cerebellar purkinje cells and is known to be important for cerebellar function, as human and mouse movement disorders result from mutations in kv3.3. |
2008-02-25 |
2023-08-12 |
mouse |
| Wataru Kakegawa, Taisuke Miyazaki, Kyoichi Emi, Keiko Matsuda, Kazuhisa Kohda, Junko Motohashi, Masayoshi Mishina, Shigenori Kawahara, Masahiko Watanabe, Michisuke Yuzak. Differential regulation of synaptic plasticity and cerebellar motor learning by the C-terminal PDZ-binding motif of GluRdelta2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256267. |
the delta2 glutamate receptor (glurdelta2) is predominantly expressed in purkinje cells and plays crucial roles in cerebellar functions: glurdelta2-/- mice display ataxia and impaired motor learning. |
2008-02-25 |
2023-08-12 |
mouse |
| Elizabeth W Tringham, Jonathan R B Dupere, C Elizabeth Payne, Maria M Usowic. Protease treatment of cerebellar purkinje cells renders omega-agatoxin IVA-sensitive Ca2+ channels insensitive to inhibition by omega-conotoxin GVIA. The Journal of pharmacology and experimental therapeutics. vol 324. issue 2. 2008-02-19. PMID:17975010. |
to assess the effects of omega-ctx-gvia on p-type channels, we made patch-clamp recordings from the soma of purkinje cells in cerebellar slices of mature [postnatal days (p) 40-50, p40-50] and immature (p13-20) rats, in which p-type channels carry most of the ca(2+) channel current (>/=85%). |
2008-02-19 |
2023-08-12 |
rat |
| Neal H Barmack, Vadim Yakhnits. Functions of interneurons in mouse cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 5. 2008-02-19. PMID:18234892. |
we recorded from cerebellar interneurons (granule, unipolar brush, golgi, stellate, basket, and lugaro cells) and purkinje cells in the uvula-nodulus of anesthetized mice during vestibular stimulation. |
2008-02-19 |
2023-08-12 |
mouse |
| Laurens W J Bosman, Hajime Takechi, Jana Hartmann, Jens Eilers, Arthur Konnert. Homosynaptic long-term synaptic potentiation of the "winner" climbing fiber synapse in developing Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 4. 2008-02-14. PMID:18216188. |
by performing whole-cell recordings in purkinje cells of rat cerebellar slices, we found that the coincident activation of a purkinje cell and one of its afferent climbing fibers induces homosynaptic long-term synaptic potentiation (ltp). |
2008-02-14 |
2023-08-12 |
rat |
| Atsushi Ikeda, Taisuke Miyazaki, Sho Kakizawa, Yasushi Okuno, Soken Tsuchiya, Akira Myomoto, Shin-ya Saito, Tetsuji Yamamoto, Tetsuo Yamazaki, Masamitsu Iino, Gozoh Tsujimoto, Masahiko Watanabe, Hiroshi Takeshim. Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins. Biochemical and biophysical research communications. vol 363. issue 3. 2008-02-11. PMID:17904530. |
knockout mice lacking neural junctophilins (jp-dko) show severe motor defects and irregular cerebellar plasticity due to abolished channel crosstalk in purkinje cells (pcs). |
2008-02-11 |
2023-08-12 |
mouse |
| Shidi Zhao, Na Chen, Zhilai Yang, Li Huang, Yan Zhu, Sudong Guan, Qianfen Chen, Jin-Hui Wan. Ischemia deteriorates the spike encoding of rat cerebellar Purkinje cells by raising intracellular Ca2+. Biochemical and biophysical research communications. vol 366. issue 2. 2008-02-05. PMID:18073134. |
ischemic changes in the excitability of purkinje cells were measured by whole-cell recording in cerebellar slices of rats with less glutamate action. |
2008-02-05 |
2023-08-12 |
rat |