| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Charanjit Kaur, Gurugirijha Rathnasamy, Eng-Ang Lin. Roles of activated microglia in hypoxia induced neuroinflammation in the developing brain and the retina. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 8. issue 1. 2013-08-16. PMID:22367679. |
a similar phenomenon is observed in the hypoxic developing cerebellum in which activated amcs induced purkinje neuronal death through production of tnf-α and il-1β via their respective receptors. |
2013-08-16 |
2023-08-12 |
Not clear |
| Udo Rüb, Franziska Hoche, Ewout R Brunt, Helmut Heinsen, Kay Seidel, Domenico Del Turco, Henry L Paulson, Jürgen Bohl, Charlotte von Gall, Jean-Paul Vonsattel, Horst-Werner Korf, Wilfred F den Dunne. Degeneration of the cerebellum in Huntington's disease (HD): possible relevance for the clinical picture and potential gateway to pathological mechanisms of the disease process. Brain pathology (Zurich, Switzerland). vol 23. issue 2. 2013-08-15. PMID:22925167. |
the cerebellum of all hd patients showed a considerable atrophy, as well as a consistent loss of purkinje cells and nerve cells of the fastigial, globose, emboliform and dentate nuclei. |
2013-08-15 |
2023-08-12 |
Not clear |
| Qionger He, Heather Titley, Giorgio Grasselli, Claire Piochon, Christian Hanse. Ethanol affects NMDA receptor signaling at climbing fiber-Purkinje cell synapses in mice and impairs cerebellar LTD. Journal of neurophysiology. vol 109. issue 5. 2013-08-15. PMID:23221414. |
using whole cell patch-clamp recordings from mouse cerebellar slices, we examined whether ethanol can affect nmda receptor signaling in mature purkinje cells. |
2013-08-15 |
2023-08-12 |
mouse |
| Qionger He, Heather Titley, Giorgio Grasselli, Claire Piochon, Christian Hanse. Ethanol affects NMDA receptor signaling at climbing fiber-Purkinje cell synapses in mice and impairs cerebellar LTD. Journal of neurophysiology. vol 109. issue 5. 2013-08-15. PMID:23221414. |
these observations suggest that the sensitivity of cerebellar circuit function and plasticity to low concentrations of ethanol may be caused by an ethanol-mediated impairment of nmda receptor signaling at cf synapses onto cerebellar purkinje cells. |
2013-08-15 |
2023-08-12 |
mouse |
| Yan Qi, Jing-Yan Ge, Yi-Nan Wang, Hai-Yan Liu, Yun-Man Li, Zhong-Hui Liu, Xue-Ling Cu. Co-expression of activin receptor-interacting protein 1 and 2 in mouse nerve cells. Neuroscience letters. vol 542. 2013-08-15. PMID:23523645. |
in the present study, we found that arip1 and arip2 mrna expressions were detectable in mouse brain and their proteins were co-localized at the hypothalamus of cerebrum and granular layers in cerebellum, especially in purkinje cells. |
2013-08-15 |
2023-08-12 |
mouse |
| Yu Shin Kim, Eunchai Kang, Yuichi Makino, Sungjin Park, Jung Hoon Shin, Hongjun Song, Pierre Launay, David J Linde. Characterizing the conductance underlying depolarization-induced slow current in cerebellar Purkinje cells. Journal of neurophysiology. vol 109. issue 4. 2013-08-09. PMID:23197456. |
they are expressed in purkinje cells of the posterior cerebellum, where disc is large, and, in these cells, disc is strongly attenuated by nonselective blockers of trpm4/5. |
2013-08-09 |
2023-08-12 |
mouse |
| David Díaz, Javier S Recio, Eduardo Weruaga, José R Alons. Mild cerebellar neurodegeneration of aged heterozygous PCD mice increases cell fusion of Purkinje and bone marrow-derived cells. Cell transplantation. vol 21. issue 7. 2013-08-08. PMID:22507630. |
mild cerebellar neurodegeneration of aged heterozygous pcd mice increases cell fusion of purkinje and bone marrow-derived cells. |
2013-08-08 |
2023-08-12 |
mouse |
| Kea Joo Lee, In Sung Park, Hyun Kim, William T Greenough, Daniel T S Pak, Im Joo Rhy. Motor skill training induces coordinated strengthening and weakening between neighboring synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 23. 2013-08-06. PMID:23739975. |
motor skill training promotes the formation of parallel fiber multiple-synapse boutons (msbs) contacting dendritic spine pairs of purkinje cells in the rat cerebellum. |
2013-08-06 |
2023-08-12 |
rat |
| Azad Kumar, J Raphael Gibbs, Alexandra Beilina, Allissa Dillman, Ravindran Kumaran, Daniah Trabzuni, Mina Ryten, Robert Walker, Colin Smith, Bryan J Traynor, John Hardy, Andrew B Singleton, Mark R Cookso. Age-associated changes in gene expression in human brain and isolated neurons. Neurobiology of aging. vol 34. issue 4. 2013-08-01. PMID:23177596. |
we then repeated the analysis in a subset of samples using laser capture microdissection to isolate purkinje neurons from the cerebellum. |
2013-08-01 |
2023-08-12 |
human |
| Y Zhao, J Xiao, S Gong, J A Clara, M S Ledou. Neural expression of the transcription factor THAP1 during development in rat. Neuroscience. vol 231. 2013-07-25. PMID:23219941. |
in addition to purkinje cells in the cerebellum, thap1-ir was also localized to pyramidal neurons in the cerebral cortex, relay neurons in the thalamus, medium spiny and cholinergic neurons in the striatum, dopaminergic neurons in the substantia nigra, and pyramidal and interneurons in the hippocampus. |
2013-07-25 |
2023-08-12 |
rat |
| A Kumazawa, N Mita, M Hirasawa, T Adachi, H Suzuki, N Shafeghat, A B Kulkarni, K Mikoshiba, T Inoue, T Ohshim. Cyclin-dependent kinase 5 is required for normal cerebellar development. Molecular and cellular neurosciences. vol 52. 2013-07-22. PMID:23085039. |
we previously reported that cdk5 knockout (ko) mice exhibit perinatal lethality, defective neuronal migration, and abnormal positioning of neurons in the facial motor nucleus and inferior olive in the hindbrain and purkinje cells (pcs) in the cerebellum. |
2013-07-22 |
2023-08-12 |
mouse |
| Zuzana Šišková, Richard A Reynolds, Vincent O'Connor, V Hugh Perr. Brain region specific pre-synaptic and post-synaptic degeneration are early components of neuropathology in prion disease. PloS one. vol 8. issue 1. 2013-07-19. PMID:23383030. |
in contrast, the pathology in the cerebellum suggested that dendritic disintegration rather than pre-synaptic abnormalities dominate the early degenerative changes associated with the purkinje cells. |
2013-07-19 |
2023-08-12 |
Not clear |
| Hiroshi Todaka, Tetsuya Tatsukawa, Tsutomu Hashikawa, Yuchio Yanagawa, Katsuei Shibuki, Soichi Naga. Heterotrimeric guanosine triphosphate-binding protein-coupled modulatory actions of motilin on K+ channels and postsynaptic γ-aminobutyric acid receptors in mouse medial vestibular nuclear neurons. The European journal of neuroscience. vol 37. issue 3. 2013-07-15. PMID:23136934. |
previous anatomical and unit recording studies suggest that a group of cerebellar purkinje cells express motilin receptors, and motilin depresses the spike discharges of vestibular nuclear neurons that receive direct cerebellar inhibition in rats or rabbits. |
2013-07-15 |
2023-08-12 |
mouse |
| Hiroshi Todaka, Tetsuya Tatsukawa, Tsutomu Hashikawa, Yuchio Yanagawa, Katsuei Shibuki, Soichi Naga. Heterotrimeric guanosine triphosphate-binding protein-coupled modulatory actions of motilin on K+ channels and postsynaptic γ-aminobutyric acid receptors in mouse medial vestibular nuclear neurons. The European journal of neuroscience. vol 37. issue 3. 2013-07-15. PMID:23136934. |
a small number of mvns, as well as cerebellar floccular purkinje cells, were labeled with an anti-motilin receptor antibody. |
2013-07-15 |
2023-08-12 |
mouse |
| E A Gilbert, Y H Lim, M K Vickaryous, C L Armstron. Heterochronic protein expression patterns in the developing embryonic chick cerebellum. Anatomical record (Hoboken, N.J. : 2007). vol 295. issue 10. 2013-07-08. PMID:22865685. |
presumptive cb+ purkinje cells are first observed at embryonic day (e)10 in clusters in posterior cerebellum. |
2013-07-08 |
2023-08-12 |
mouse |
| E A Gilbert, Y H Lim, M K Vickaryous, C L Armstron. Heterochronic protein expression patterns in the developing embryonic chick cerebellum. Anatomical record (Hoboken, N.J. : 2007). vol 295. issue 10. 2013-07-08. PMID:22865685. |
at e12, corresponding with global expression of cb across the cerebellum, purkinje cells began to express zii. |
2013-07-08 |
2023-08-12 |
mouse |
| Neil I Weisenfeld, Jurriaan M Peters, Peter T Tsai, Sanjay P Prabhu, Kira A Dies, Mustafa Sahin, Simon K Warfiel. A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex. Pediatric neurology. vol 48. issue 2. 2013-07-02. PMID:23337002. |
the cerebellum calls for specific attention because mouse models of tuberous sclerosis complex have demonstrated a loss of cerebellar purkinje cells, and cases of human histologic data have demonstrated a similar loss in patients. |
2013-07-02 |
2023-08-12 |
mouse |
| Masae Naruse, Koji Shibasaki, Shuichi Yokoyama, Masashi Kurachi, Yasuki Ishizak. Dynamic changes of CD44 expression from progenitors to subpopulations of astrocytes and neurons in developing cerebellum. PloS one. vol 8. issue 1. 2013-07-01. PMID:23308146. |
cd44 expression was also detected in developing purkinje and granule neurons but was limited to granule neurons in the adult cerebellum. |
2013-07-01 |
2023-08-12 |
mouse |
| Azubike P Ebokaiwe, Isaac A Adedara, Olatunde Owoeye, Ebenezer O Faromb. Neurotoxicity of Nigerian bonny light crude oil in rats. Drug and chemical toxicology. vol 36. issue 2. 2013-06-28. PMID:23020769. |
although the purkinje layer and maximum width of purkinje cells were not affected, blco treatment significantly decreased molecular layer, granular layer, and density of purkinje cells of the cerebellum. |
2013-06-28 |
2023-08-12 |
rat |
| Stephen T Hansen, Pratap Meera, Thomas S Otis, Stefan M Puls. Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. Human molecular genetics. vol 22. issue 2. 2013-06-17. PMID:23087021. |
like other ataxias, sca2 most overtly affects purkinje cells (pcs) in the cerebellum. |
2013-06-17 |
2023-08-12 |
mouse |