| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Micaela Galante, Marco A Dian. Group I metabotropic glutamate receptors inhibit GABA release at interneuron-Purkinje cell synapses through endocannabinoid production. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 20. 2004-09-10. PMID:15152047. |
actions of endocannabinoids in the cerebellum can be demonstrated following distinct stimulation protocols in purkinje cells. |
2004-09-10 |
2023-08-12 |
Not clear |
| Taekyun Shin, Daniel Weinstock, Marlene D Castro, Amir N Hamir, Thomas Wampler, Mark Walter, Hyun Young Kim, Helen Aclan. Immunohistochemical localization of endothelial and inducible nitric oxide synthase within neurons of cattle with rabies. The Journal of veterinary medical science. vol 66. issue 5. 2004-09-09. PMID:15187365. |
increased expression of enos was detected in neurons of the brain stem and purkinje cells of cerebellum. |
2004-09-09 |
2023-08-12 |
cattle |
| N Hirano, R Nomura, T Tawara, K Tohyam. Neurotropism of swine haemagglutinating encephalomyelitis virus (coronavirus) in mice depending upon host age and route of infection. Journal of comparative pathology. vol 130. issue 1. 2004-09-07. PMID:14693125. |
viral antigen was first detected immunohistochemically in the lumbar spinal cord and the dorsal root ganglion ipsilateral to the inoculated leg; it was detected later in the pyramidal cells of the hippocampus and cerebral cortex, and in the purkinje cells of the cerebellum but not in the ependymal cells, choroid plexus cells or other glial cells. |
2004-09-07 |
2023-08-12 |
mouse |
| Kazuyoshi Tsutsui, Hirotaka Sakamoto, Hanako Shikimi, Kazuyoshi Uken. Organizing actions of neurosteroids in the Purkinje neuron. Neuroscience research. vol 49. issue 3. 2004-09-07. PMID:15196775. |
subsequently the actions of progesterone and estradiol during cerebellar development have become clear by a series of our studies using an excellent purkinje cellular model. |
2004-09-07 |
2023-08-12 |
Not clear |
| S Tanaka, M Takagi, T Miyazak. Histopathological studies on viral nervous necrosis of sevenband grouper, Epinephelus septemfasciatus Thunberg, at the grow-out stage. Journal of fish diseases. vol 27. issue 7. 2004-08-27. PMID:15228608. |
purkinje cells and golgi cells were extensively infected in the cerebellum. |
2004-08-27 |
2023-08-12 |
Not clear |
| L A Martin, T Escher, D Goldowitz, G Mittlema. A relationship between cerebellar Purkinje cells and spatial working memory demonstrated in a lurcher/chimera mouse model system. Genes, brain, and behavior. vol 3. issue 3. 2004-08-26. PMID:15140011. |
through histological examination of chimeric mice and observations of motor ability, we showed that ataxia is dependent upon both the number and distribution of purkinje cells in the cerebellum. |
2004-08-26 |
2023-08-12 |
mouse |
| Cynthia S Duchala, H Elizabeth Shick, Jessica Garcia, Dannette M Deweese, Xiaoyan Sun, Valerie J Stewart, Wendy B Mackli. The toppler mouse: a novel mutant exhibiting loss of Purkinje cells. The Journal of comparative neurology. vol 476. issue 2. 2004-08-26. PMID:15248193. |
given the changes in both purkinje cells and glia in toppler cerebellum, this may be a very useful model in which to investigate the developmental interaction of purkinje cells and bergmann glia. |
2004-08-26 |
2023-08-12 |
mouse |
| Michisuke Yuzak. The delta2 glutamate receptor: a key molecule controlling synaptic plasticity and structure in Purkinje cells. Cerebellum (London, England). vol 3. issue 2. 2004-08-23. PMID:15233575. |
the orphan glutamate receptor delta2 (glurdelta2) is predominantly expressed in cerebellar purkinje cells and plays a crucial role in cerebellar functions; mice that lack the glurdelta2 gene display ataxia and impaired motor-related learning tasks. |
2004-08-23 |
2023-08-12 |
mouse |
| Lisa Kreiner, Dieter Jaege. Synaptic shunting by a baseline of synaptic conductances modulates responses to inhibitory input volleys in cerebellar Purkinje cells. Cerebellum (London, England). vol 3. issue 2. 2004-08-23. PMID:15233579. |
specifically we examine the processing of inhibitory input transients in cerebellar purkinje cells, which by inducing pauses in purkinje cell spike activity may lead to a disinhibition of the deep cerebellar nuclei and thus to cerebellar motor command signals. |
2004-08-23 |
2023-08-12 |
Not clear |
| Hee-Kyung Jin, Edward H Schuchma. Ex vivo gene therapy using bone marrow-derived cells: combined effects of intracerebral and intravenous transplantation in a mouse model of Niemann-Pick disease. Molecular therapy : the journal of the American Society of Gene Therapy. vol 8. issue 6. 2004-08-18. PMID:14664789. |
cerebellar function also was normal, and the number of purkinje cells was > 80% of normal. |
2004-08-18 |
2023-08-12 |
mouse |
| Hee-Kyung Jin, Edward H Schuchma. Ex vivo gene therapy using bone marrow-derived cells: combined effects of intracerebral and intravenous transplantation in a mouse model of Niemann-Pick disease. Molecular therapy : the journal of the American Society of Gene Therapy. vol 8. issue 6. 2004-08-18. PMID:14664789. |
remarkably, in certain regions of the cerebellum many of the surviving purkinje cells expressed human asm rna, suggesting that either they were donor-derived or that the transplanted bone marrow cells had fused with existing purkinje cells. |
2004-08-18 |
2023-08-12 |
mouse |
| Haiyan Fu, Joseph Muenzer, Richard J Samulski, George Breese, Jerillyn Sifford, Xinhua Zeng, Douglas M McCart. Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain. Molecular therapy : the journal of the American Society of Gene Therapy. vol 8. issue 6. 2004-08-18. PMID:14664793. |
more than 50% of the purkinje cells in the cerebellum expressed gfp. |
2004-08-18 |
2023-08-12 |
mouse |
| Maria L Florez-McClure, Daniel A Linseman, Charleen T Chu, Phil A Barker, Ron J Bouchard, Shoshona S Le, Tracey A Laessig, Kim A Heidenreic. The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 19. 2004-08-13. PMID:15140920. |
although treatment with antisense oligonucleotides to the p75 neurotrophin receptor (p75ntr) decreased basal survival of cultured cerebellar neurons, p75ntr-antisense decreased autophagy and completely inhibited death of purkinje neurons induced by trophic factor withdrawal. |
2004-08-13 |
2023-08-12 |
Not clear |
| Paula M Lewis, Amel Gritli-Linde, Richard Smeyne, Andreas Kottmann, Andrew P McMaho. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Developmental biology. vol 270. issue 2. 2004-08-12. PMID:15183722. |
sonic hedgehog (shh) is produced by purkinje cells of the cerebellum and is a potent inducer of granule cell proliferation. |
2004-08-12 |
2023-08-12 |
mouse |
| Paula M Lewis, Amel Gritli-Linde, Richard Smeyne, Andreas Kottmann, Andrew P McMaho. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Developmental biology. vol 270. issue 2. 2004-08-12. PMID:15183722. |
to better determine the role of shh during cerebellar development, we genetically removed shh activity specifically from purkinje cells and the cerebellar anlage of the mouse embryo. |
2004-08-12 |
2023-08-12 |
mouse |
| Mary D Womack, Kamran Khodakha. Dendritic control of spontaneous bursting in cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 14. 2004-08-03. PMID:15071098. |
we investigated the mechanisms that contribute to spontaneous regular bursting in adult purkinje neurons in acutely prepared cerebellar slices. |
2004-08-03 |
2023-08-12 |
Not clear |
| Hiroshi Nishiyama, David J Linde. Differential maturation of climbing fiber innervation in cerebellar vermis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 16. 2004-08-03. PMID:15102908. |
using whole-cell recording from slices of cerebellar vermis derived from juvenile (p18-25) or adult (p60-83) mice, we found that significantly more purkinje cells in the sulcus were innervated by multiple climbing fibers than in the gyrus or bank subdivisions; however, the basic properties of climbing fiber-purkinje cell epscs such as kinetics, amplitude, and paired-pulse ratio were similar across cortical subdivisions. |
2004-08-03 |
2023-08-12 |
mouse |
| Anne-Fleur van Rootselaar, Eleonora Aronica, Ernst N H Jansen Steur, Johanna M Rozemuller-Kwakkel, Rob A I de Vos, Marina A J Tijsse. Familial cortical tremor with epilepsy and cerebellar pathological findings. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 2. 2004-08-02. PMID:14978679. |
pathological investigation showed cerebellar degeneration and somal sprouting and loss of dendritic tree in purkinje cells. |
2004-08-02 |
2023-08-12 |
Not clear |
| Elan D Louis, Michael J Murray, Melissa A Miller, Seth L Pullman, Jean Paul G Vonsatte. Late-life action tremor in a southern sea otter (enhydris lutris nereis). Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 2. 2004-08-02. PMID:14978682. |
the main pathological finding was in the cerebellum, where there was extensive vacuolation of purkinje cells. |
2004-08-02 |
2023-08-12 |
human |
| Benedetto Sacchetti, Bibiana Scelfo, Filippo Tempia, Piergiorgio Strat. Long-term synaptic changes induced in the cerebellar cortex by fear conditioning. Neuron. vol 42. issue 6. 2004-08-02. PMID:15207241. |
in cerebellar slices at 10 min and 24 hr following fear conditioning, we found a long-lasting potentiation of the synapse between parallel fibers and purkinje cells in vermal lobules v-vi, but not in the climbing fiber synapses. |
2004-08-02 |
2023-08-12 |
mouse |