| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Huang, Angélique Borde. Glial glutamate transporters limit spillover activation of presynaptic NMDA receptors and influence synaptic inhibition of Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 25. 2004-11-24. PMID:15215288. |
single and paired whole-cell patch-clamp recordings were obtained from purkinje neurons and bergmann glia in mouse cerebellar slices to determine the function of neuronal and glial glutamate transporters at gabaergic synapses onto purkinje neurons. |
2004-11-24 |
2023-08-12 |
mouse |
| S S Zhokhov, I A Kostanyan, N V Gibanova, E A Surina, Z I Storozheva, I I Babichenko, V M Lipki. Similarity and difference in the effects of peptides TGENHR and TQVEHR on HL-60 promyelocytes and Purkinje cells of rat cerebellar vermis. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. vol 394. 2004-11-16. PMID:15088395. |
similarity and difference in the effects of peptides tgenhr and tqvehr on hl-60 promyelocytes and purkinje cells of rat cerebellar vermis. |
2004-11-16 |
2023-08-12 |
rat |
| Nina Schumacher, Johanna M Borawski, Cornelia B Leberfinger, Manfred Gessler, Eugen Kerkhof. Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain. Gene expression patterns : GEP. vol 4. issue 3. 2004-11-15. PMID:15053972. |
in the adult brain high expression of the genes was found in the purkinje cells of the cerebellum and in neuronal cells of the hippocampus and dentate gyrus. |
2004-11-15 |
2023-08-12 |
mouse |
| Koji Ohira, Nobuo Funatsu, Shun Nakamura, Motoharu Hayash. Expression of BDNF and TrkB receptor subtypes in the postnatal developing Purkinje cells of monkey cerebellum. Gene expression patterns : GEP. vol 4. issue 3. 2004-11-15. PMID:15053973. |
expression of bdnf and trkb receptor subtypes in the postnatal developing purkinje cells of monkey cerebellum. |
2004-11-15 |
2023-08-12 |
monkey |
| Steven U Walkley, Kinuko Suzuk. Consequences of NPC1 and NPC2 loss of function in mammalian neurons. Biochimica et biophysica acta. vol 1685. issue 1-3. 2004-11-15. PMID:15465426. |
as the disease progresses, neurodegeneration is also apparent for neurons in some brain regions, particularly purkinje cells of the cerebellum, but the basis of this selective neuronal vulnerability is unknown. |
2004-11-15 |
2023-08-12 |
caenorhabditis_elegans |
| E O'Hearn, M E Mollive. Administration of a non-NMDA antagonist, GYKI 52466, increases excitotoxic Purkinje cell degeneration caused by ibogaine. Neuroscience. vol 127. issue 2. 2004-11-09. PMID:15262328. |
we previously reported that ibogaine, administered systemically, produces degeneration of a subset of purkinje cells in the cerebellum, primarily within the vermis. |
2004-11-09 |
2023-08-12 |
human |
| Scott A Norris, Bradley Greger, Emily N Hathaway, W Thomas Thac. Purkinje cell spike firing in the posterolateral cerebellum: correlation with visual stimulus, oculomotor response, and error feedback. Journal of neurophysiology. vol 92. issue 3. 2004-11-04. PMID:15128755. |
complex (cs)- and simple-spike (ss) discharge from single purkinje cells (pc) in the posterolateral cerebellum of two monkeys was recorded during a visually guided reach-touch task. |
2004-11-04 |
2023-08-12 |
monkey |
| Jennifer L Anderson, Stewart I Head, John W Morle. Long-term depression is reduced in cerebellar Purkinje cells of dystrophin-deficient mdx mice. Brain research. vol 1019. issue 1-2. 2004-11-04. PMID:15306266. |
using a cerebellar slice preparation, we show that postsynaptically mediated long-term depression (ltd) is significantly reduced in mdx purkinje cells, while presynaptically mediated paired-pulse facilitation (ppf) is normal. |
2004-11-04 |
2023-08-12 |
mouse |
| C M A Reijnders, J G Koster, S C van Buul-Offer. Overexpression of human IGF-II mRNA in the brain of transgenic mice modulates IGFBP-2 gene expression in the medulla oblongata. The Journal of endocrinology. vol 182. issue 3. 2004-11-01. PMID:15350186. |
in general, this pattern is comparable to the expression pattern of endogenous igf-i, with a few exceptions: there is no expression of igf-i in the granular layer of the cerebellum, whereas the purkinje cells of the cerebellum and thalamus both express igf-i but no higf-ii transgene. |
2004-11-01 |
2023-08-12 |
mouse |
| Robert Papay, Robert Gaivin, Dan F McCune, Boyd R Rorabaugh, Wendy B Macklin, John C McGrath, Dianne M Pere. Mouse alpha1B-adrenergic receptor is expressed in neurons and NG2 oligodendrocytes. The Journal of comparative neurology. vol 478. issue 1. 2004-10-29. PMID:15334645. |
the alpha1b-ar-egfp fusion protein is expressed in neurons throughout the brain and in the purkinje cells of the cerebellum. |
2004-10-29 |
2023-08-12 |
mouse |
| Katrin Müller-Schmehl, Julia Beninde, Barbara Finckh, Simone Florian, Joachim W Dudenhausen, Regina Brigelius-Flohé, Markus Schuelk. Localization of alpha-tocopherol transfer protein in trophoblast, fetal capillaries' endothelium and amnion epithelium of human term placenta. Free radical research. vol 38. issue 4. 2004-10-21. PMID:15190938. |
alpha-tocopherol transfer protein (ttpa) is expressed in liver and in purkinje cells of the cerebellum. |
2004-10-21 |
2023-08-12 |
mouse |
| A Mattsson, K Pernold, S O Ogren, L Olso. Loss of cortical acetylcholine enhances amphetamine-induced locomotor activity. Neuroscience. vol 127. issue 3. 2004-10-18. PMID:15283958. |
delivery of 192 igg-saporin also destroys a population of purkinje neurons in cerebellum, this cell loss needs to be taken into consideration as well. |
2004-10-18 |
2023-08-12 |
rat |
| A Mattsson, K Pernold, S O Ogren, L Olso. Loss of cortical acetylcholine enhances amphetamine-induced locomotor activity. Neuroscience. vol 127. issue 3. 2004-10-18. PMID:15283958. |
selective loss of purkinje cells in cerebellum was achieved by i.c.v. |
2004-10-18 |
2023-08-12 |
rat |
| Rosa H Huang, Chi-Ming Huan. An experimental method for measuring the mean length of cerebellar parallel fibers: validation and derivation of a correction factor by computational simulation and probability analysis. Brain research bulletin. vol 64. issue 1. 2004-10-15. PMID:15275952. |
the length of cerebellar parallel fibers is important for information integration by the purkinje cells. |
2004-10-15 |
2023-08-12 |
Not clear |
| Edward S Boyden, Akira Katoh, Jennifer L Raymon. Cerebellum-dependent learning: the role of multiple plasticity mechanisms. Annual review of neuroscience. vol 27. 2004-10-13. PMID:15217344. |
the model that has influenced much of the work in the field for the past 30 years suggests that motor learning is mediated by a single plasticity mechanism in the cerebellum: long-term depression (ltd) of parallel fiber synapses onto purkinje cells. |
2004-10-13 |
2023-08-12 |
Not clear |
| Haibin Xia, Qinwen Mao, Steven L Eliason, Scott Q Harper, Inês H Martins, Harry T Orr, Henry L Paulson, Linda Yang, Robert M Kotin, Beverly L Davidso. RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nature medicine. vol 10. issue 8. 2004-10-04. PMID:15235598. |
upon intracerebellar injection, recombinant adeno-associated virus (aav) vectors expressing short hairpin rnas profoundly improved motor coordination, restored cerebellar morphology and resolved characteristic ataxin-1 inclusions in purkinje cells of sca1 mice. |
2004-10-04 |
2023-08-12 |
mouse |
| Robert F Mille. D-Serine as a glial modulator of nerve cells. Glia. vol 47. issue 3. 2004-10-04. PMID:15252817. |
d-serine also plays a role in synaptic and cellular development, particularly in the cerebellum, where the normal developmental sequences underlying synapse formation onto purkinje cells and the migration of granule cells are dependent on nmda receptors during a time when high levels of d-serine are expressed in the bergmann glia and other cerebellar astrocytes. |
2004-10-04 |
2023-08-12 |
Not clear |
| A I Gulyas, B F Cravatt, M H Bracey, T P Dinh, D Piomelli, F Boscia, T F Freun. Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala. The European journal of neuroscience. vol 20. issue 2. 2004-09-30. PMID:15233753. |
in the cerebellum, purkinje cells and their dendrites are intensively immunoreactive for faah, together with a sparse axon plexus at the border of the purkinje cell/granule cell layers. |
2004-09-30 |
2023-08-12 |
rat |
| Yoshinori Mikami, Tomoyuki Yoshida, Naoto Matsuda, Masayoshi Mishin. Expression of zebrafish glutamate receptor delta2 in neurons with cerebellum-like wiring. Biochemical and biophysical research communications. vol 322. issue 1. 2004-09-30. PMID:15313188. |
mammalian glutamate receptor (glur) delta2 is selectively expressed in cerebellar purkinje cells and plays key roles in cerebellar plasticity, motor learning, and neural wiring. |
2004-09-30 |
2023-08-12 |
zebrafish |
| Takeshi Uemura, Hisashi Mori, Masayoshi Mishin. Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Molecular and cellular neurosciences. vol 26. issue 2. 2004-09-29. PMID:15207857. |
glutamate receptor (glur) delta2 selectively expressed in cerebellar purkinje cells plays a central role in cerebellar long-term depression (ltd), motor learning, and formation of parallel fiber synapses. |
2004-09-29 |
2023-08-12 |
Not clear |