| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiankai Luo, Christoph Redie. Overexpression of genes in Purkinje cells in the embryonic chicken cerebellum by in vivo electroporation. Journal of neuroscience methods. vol 139. issue 2. 2005-01-19. PMID:15488237. |
in the present work, we establish an efficient in vivo electroporation technique to transfer genes into purkinje cells of the developing chicken cerebellum, as demonstrated by green fluorescent protein. |
2005-01-19 |
2023-08-12 |
chicken |
| JoMichelle D Corrales, Gina L Rocco, Sandra Blaess, Qiuxia Guo, Alexandra L Joyne. Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development (Cambridge, England). vol 131. issue 22. 2005-01-18. PMID:15496441. |
since the secreted factor sonic hedgehog (shh) is expressed in purkinje cells and functions as a gcp mitogen in vitro, it is possible that shh influences foliation during cerebellum development by regulating the position and/or size of lobes. |
2005-01-18 |
2023-08-12 |
mouse |
| JoMichelle D Corrales, Gina L Rocco, Sandra Blaess, Qiuxia Guo, Alexandra L Joyne. Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development (Cambridge, England). vol 131. issue 22. 2005-01-18. PMID:15496441. |
by contrast, gli2 is expressed uniformly in all cells in the developing cerebellum except purkinje cells and gli3 is broadly expressed along the anteroposterior axis. |
2005-01-18 |
2023-08-12 |
mouse |
| Akiko Arata, Masao It. Purkinje cell functions in the in vitro cerebellum isolated from neonatal rats in a block with the pons and medulla. Neuroscience research. vol 50. issue 3. 2005-01-14. PMID:15488299. |
electrophysiological and optical recordings revealed that, at postnatal days 4-8 (p4-p8), purkinje cells in the lateral portion of the cerebellum responded to the stimulation of climbing fiber afferents at the inferior olive and of parallel fibers at the posterior vermis, and that the combination of these inputs induced long-term depression. |
2005-01-14 |
2023-08-12 |
rat |
| Akiko Arata, Masao It. Purkinje cell functions in the in vitro cerebellum isolated from neonatal rats in a block with the pons and medulla. Neuroscience research. vol 50. issue 3. 2005-01-14. PMID:15488299. |
these observations and pharmacological testings indicate that certain functional features of purkinje cells mature around p5 in the lateral portion of the cerebellum. |
2005-01-14 |
2023-08-12 |
rat |
| Louise E Coverdale, Christopher J Martyniuk, Vance L Trudeau, C Cristofre Marti. Differential expression of the methyl-cytosine binding protein 2 gene in embryonic and adult brain of zebrafish. Brain research. Developmental brain research. vol 153. issue 2. 2005-01-13. PMID:15527897. |
in the cerebellum, high expression is found in the purkinje and golgi type 2 cells. |
2005-01-13 |
2023-08-12 |
xenopus_laevis |
| Youssef Sar. Serotonin1B receptors: from protein to physiological function and behavior. Neuroscience and biobehavioral reviews. vol 28. issue 6. 2005-01-11. PMID:15527863. |
the regulation of gamma-aminobutyric acid release by 5-ht1b receptors has been found in projections: from caudate putamen to the globus pallidus or substantia nigra, from nucleus accumbens to the ventral tegmentum area, and from purkinje neurons to the deep nuclei of the cerebellum. |
2005-01-11 |
2023-08-12 |
human |
| Pablo M Blazquez, Yutaka Hirata, Stephen M Highstei. The vestibulo-ocular reflex as a model system for motor learning: what is the role of the cerebellum? Cerebellum (London, England). vol 3. issue 3. 2005-01-11. PMID:15543809. |
recent studies also suggest that the signal content in the cerebellum changes following learning and that the mechanisms used for chronic adaptation involve not only changes in a head velocity component but also in the efference copy of an eye movement command signal reaching purkinje cells. |
2005-01-11 |
2023-08-12 |
mouse |
| John T Gree. The effects of ethanol on the developing cerebellum and eyeblink classical conditioning. Cerebellum (London, England). vol 3. issue 3. 2005-01-11. PMID:15543808. |
binge-like ethanol exposure of neonatal rats depletes cells in the cerebellum, including purkinje cells, granule cells, and deep nuclear cells, and produces deficits in simple tests of motor coordination. |
2005-01-11 |
2023-08-12 |
human |
| Michelle B Warren, Carlos A Torres-Cabala, Maria L Turner, Maria J Merino, Vera Y Matrosova, Michael L Nickerson, Wenbin Ma, W Marston Linehan, Berton Zbar, Laura S Schmid. Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. vol 17. issue 8. 2005-01-05. PMID:15143337. |
in the brain, bhd mrna was expressed in neurons of the cerebrum, and purkinje cells in the cerebellum. |
2005-01-05 |
2023-08-12 |
human |
| Y Mochizuki, A Kawata, T Mizutani, K Takamoto, H Hayashi, K Taki, Y Morimats. Hereditary paroxysmal ataxia with mental retardation: a clinicopathological study in relation to episodic ataxia type 2. Acta neuropathologica. vol 108. issue 4. 2004-12-23. PMID:15300451. |
neuropathologically, cortical degeneration consisting of the marked loss of purkinje and granule cells was found exclusively in the cerebellar vermis. |
2004-12-23 |
2023-08-12 |
human |
| Y Mochizuki, A Kawata, T Mizutani, K Takamoto, H Hayashi, K Taki, Y Morimats. Hereditary paroxysmal ataxia with mental retardation: a clinicopathological study in relation to episodic ataxia type 2. Acta neuropathologica. vol 108. issue 4. 2004-12-23. PMID:15300451. |
in addition, there were minor anomalies, such as hypoplastic cerebellum and brainstem, heterotopic purkinje cells, and cortical microdysgenesis of the temporal lobe. |
2004-12-23 |
2023-08-12 |
human |
| N Gharani, R Benayed, V Mancuso, L M Brzustowicz, J H Milloni. Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder. Molecular psychiatry. vol 9. issue 5. 2004-12-22. PMID:15024396. |
mouse mutants of the homeobox transcription factor engrailed2 (en2) and autistic individuals display similar cerebellar morphological abnormalities, which include hypoplasia and a decrease in the number of purkinje cells. |
2004-12-22 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Masahiro Ando, Hiromi Sakata-Haga, Xue-Zhi Sun, Young-Gil Jeong, Setsuji Hisano, Noriaki Takeda, Yoshihiro Fuku. Abnormal expression of tyrosine hydroxylase not accompanied by phosphorylation at serine 40 in cerebellar Purkinje cells of ataxic mutant mice, rolling mouse Nagoya and dilute-lethal. Congenital anomalies. vol 44. issue 1. 2004-12-21. PMID:15008900. |
in all groups of mice, there were no phospho-th immunoreactive purkinje cells in the cerebellum, although the subsets of th immunoreactive purkinje cells were found in the adjacent sections. |
2004-12-21 |
2023-08-12 |
mouse |
| Ke-Min Chen, Hsiu-Hsiung Lee, Kuang-Hui Lu, Yu-Kai Tseng, Li-Sung Hsu, Hui-Lin Chou, Shih-Chan La. Association of matrix metalloproteinase-9 and Purkinje cell degeneration in mouse cerebellum caused by Angiostrongylus cantonensis. International journal for parasitology. vol 34. issue 10. 2004-12-17. PMID:15380686. |
these results suggested that the expression of matrix metalloproteinase-9 may be associated with degeneration of purkinje cells in mouse cerebellum infected by a. cantonensis. |
2004-12-17 |
2023-08-12 |
mouse |
| Carl Y Saab, Matthew J Craner, Yuko Kataoka, Stephen G Waxma. Abnormal Purkinje cell activity in vivo in experimental allergic encephalomyelitis. Experimental brain research. vol 158. issue 1. 2004-12-13. PMID:15118796. |
although the pathophysiological basis for these deficits is not clear, it was recently reported that the expression of the sensory neuron-specific sodium channel nav1.8 (which is not normally expressed within the cerebellum) is aberrantly upregulated within purkinje cells in experimental allergic encephalomyelitis (eae) and in human ms. |
2004-12-13 |
2023-08-12 |
mouse |
| Carl Y Saab, Matthew J Craner, Yuko Kataoka, Stephen G Waxma. Abnormal Purkinje cell activity in vivo in experimental allergic encephalomyelitis. Experimental brain research. vol 158. issue 1. 2004-12-13. PMID:15118796. |
these results demonstrate functional changes in purkinje cells in vivo within their native cerebellar environment in eae, a model of ms, and support the hypothesis that misexpression of nav1.8 can contribute to cerebellar deficits in neuroinflammatory disorders by altering the pattern of electrical activity within the cerebellum. |
2004-12-13 |
2023-08-12 |
mouse |
| Luis Bataller, Lidia Sabater, Albert Saiz, Carles Serra, Berta Claramonte, Francesc Grau. Carbonic anhydrase-related protein VIII: autoantigen in paraneoplastic cerebellar degeneration. Annals of neurology. vol 56. issue 4. 2004-12-02. PMID:15389893. |
serum of a patient with paraneoplastic cerebellar degeneration (pcd) and malignant melanoma had a unique reactivity with purkinje cells that was not observed in serum of patients with pcd and other tumors, or with malignant melanoma without paraneoplastic syndromes. |
2004-12-02 |
2023-08-12 |
human |
| Brad Bryan, Vikas Kumar, Lewis Joe Stafford, Yi Cai, Gangyi Wu, Mingyao Li. GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation. The Journal of biological chemistry. vol 279. issue 44. 2004-11-30. PMID:15322108. |
we demonstrate that a newly identified guanine nucleotide exchange factor, geft, is widely expressed in the brain and highly concentrated in the hippocampus, and the purkinje and granular cells of the cerebellum. |
2004-11-30 |
2023-08-12 |
Not clear |
| Fabrice Ango, Graziella di Cristo, Hiroyuki Higashiyama, Vann Bennett, Priscilla Wu, Z Josh Huan. Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment. Cell. vol 119. issue 2. 2004-11-30. PMID:15479642. |
in cerebellum, for example, basket interneurons make exquisitely precise "pinceau synapses" on ais of purkinje neurons, but the underlying mechanism is unknown. |
2004-11-30 |
2023-08-12 |
mouse |