| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer E Slemmer, John T Weber, Chris I De Zeeu. Cell death, glial protein alterations and elevated S-100 beta release in cerebellar cell cultures following mechanically induced trauma. Neurobiology of disease. vol 15. issue 3. 2004-05-27. PMID:15056464. |
recent studies in vivo have shown that cells of the cerebellum, and particularly purkinje neurons (pns), are susceptible to damage following traumatic brain injury (tbi). |
2004-05-27 |
2023-08-12 |
Not clear |
| M Calissano, E Ensor, D R Brown, D S Latchma. Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors. Neuroreport. vol 15. issue 3. 2004-05-20. PMID:15094508. |
while a structural modification of prp is necessary and sufficient for its toxic effect, the neurotoxicity of doppel in the purkinje cells of the cerebellum relies solely on its overexpression. |
2004-05-20 |
2023-08-12 |
mouse |
| Jiankai Luo, Ullrich Treubert-Zimmermann, Christoph Redie. Cadherins guide migrating Purkinje cells to specific parasagittal domains during cerebellar development. Molecular and cellular neurosciences. vol 25. issue 1. 2004-05-19. PMID:14962747. |
cadherins guide migrating purkinje cells to specific parasagittal domains during cerebellar development. |
2004-05-19 |
2023-08-12 |
chicken |
| Chitoshi Takayama, Yoshiro Inou. Transient expression of GABAA receptor alpha2 and alpha3 subunits in differentiating cerebellar neurons. Brain research. Developmental brain research. vol 148. issue 2. 2004-05-07. PMID:14766194. |
hybridization signals for the alpha3 subunit mrna, on the other hand, were localized in the developing purkinje cells and cerebellar nucleus neurons, and disappeared from purkinje cells by the end of first postnatal week. |
2004-05-07 |
2023-08-12 |
mouse |
| Eli M Mrkusich, Bronwyn M Kivell, John H Miller, Darren J Da. Abundant expression of mu and delta opioid receptor mRNA and protein in the cerebellum of the fetal, neonatal, and adult rat. Brain research. Developmental brain research. vol 148. issue 2. 2004-05-07. PMID:14766199. |
in this study, we report detection of mor as well as dor protein by immunohistochemical localization, and mrna by fluorescent in situ hybridization (fish) within purkinje cells (pk) and the granular layer of neonatal (p6) and adult rat cerebellum. |
2004-05-07 |
2023-08-12 |
rat |
| Tomoko Nagase, Nobuyuki Shimozawa, Yasuhiko Takemoto, Yasuyuki Suzuki, Masayuki Komori, Naomi Kond. Peroxisomal localization in the developing mouse cerebellum: implications for neuronal abnormalities related to deficiencies in peroxisomes. Biochimica et biophysica acta. vol 1671. issue 1-3. 2004-05-06. PMID:15026142. |
in cultured cells from the mouse cerebellum, peroxisomes were few in purkinje cells, whereas many were evident in glial fibrillary acidic protein-positive cells. |
2004-05-06 |
2023-08-12 |
mouse |
| Lucy Anderson, Daniela Rossi, Jackie Linehan, Sebastian Brandner, Charles Weissman. Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 10. 2004-05-05. PMID:15007176. |
to evaluate whether the two proteins caused cerebellar neurodegeneration by the same mechanism, we generated transgenic mice selectively expressing dpl in purkinje cells by the same l7 promoter. |
2004-05-05 |
2023-08-12 |
mouse |
| B Ya Ryzhavskii, E V Vasil'eva, T V Sokolov. Morphology of the cerebellum in the progeny of female rats exposed to long-term emotional stress before pregnancy. Bulletin of experimental biology and medicine. vol 135. issue 2. 2004-05-04. PMID:12802436. |
the cerebellum in the experimental group was smaller, the nucleus and cytoplasm of purkinje cells were smaller, the concentration of rna in their cytoplasm and increased, the percentage of dark purkinje cells increased, and the concentration of lipids in the molecular cortical layer and white matter decreased. |
2004-05-04 |
2023-08-12 |
rat |
| Paul Chadderton, Troy W Margrie, Michael Häusse. Integration of quanta in cerebellar granule cells during sensory processing. Nature. vol 428. issue 6985. 2004-05-04. PMID:15103377. |
in the cerebellum, granule cells constitute the input layer, translating mossy fibre signals into parallel fibre input to purkinje cells. |
2004-05-04 |
2023-08-12 |
Not clear |
| Yasuko Kitao, Kouichi Hashimoto, Tomohiro Matsuyama, Hiroyuki Iso, Takeshi Tamatani, Osamu Hori, David M Stern, Masanobu Kano, Kentaro Ozawa, Satoshi Ogaw. ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 6. 2004-04-26. PMID:14960622. |
behavioral analysis, using rotor rod tasks, indicated impairment of cerebellar function in tg orp150 animals, consistent with the concept that enhanced survival of purkinje cells results in dysfunction. |
2004-04-26 |
2023-08-12 |
mouse |
| Ping-An Li, QingPing He, Tongyu Cao, Gregory Yong, Kornelia Molnarne Szauter, Keith S K Fong, Jenny Karlsson, Marcus F Keep, Katalin Csisza. Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis. Brain research. Molecular brain research. vol 120. issue 2. 2004-04-19. PMID:14741400. |
lox immunoreactivity increased in neurons of the spinal cord, brain stem and cortex, and the purkinje cells of the cerebellum in transgenic g93a sod1 (msod1) mouse model of als. |
2004-04-19 |
2023-08-12 |
mouse |
| James S King, Georgia A Bisho. Localization of the type 1 corticotropin releasing factor receptor (CRF-R1) in the embryonic mouse cerebellum. Journal of neurocytology. vol 32. issue 3. 2004-04-16. PMID:14724392. |
between e16 and 18, purkinje cells, immunolabeled with calbindin, near the dorsal surface of the cerebellum express crf-r1 in their cell bodies and apical processes. |
2004-04-16 |
2023-08-12 |
mouse |
| C Dirk Keene, Xilma R Ortiz-Gonzalez, Yuehua Jiang, David A Largaespada, Catherine M Verfaillie, Walter C Lo. Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos. Cell transplantation. vol 12. issue 3. 2004-04-13. PMID:12797375. |
more specifically, donor-derived neurons contributed to each of the cellular layers of the cortex; the pyramidal and granule cell layers, as well as the hilus, of the hippocampus; purkinje and granule cell layers in the cerebellum; and gabaergic cells in the caudate and putamen. |
2004-04-13 |
2023-08-12 |
mouse |
| Mayumi Kondoh, Takashi Shiga, Nobuo Okad. Regulation of dendrite formation of Purkinje cells by serotonin through serotonin1A and serotonin2A receptors in culture. Neuroscience research. vol 48. issue 1. 2004-04-12. PMID:14687886. |
in the present study, we investigated the actions of serotonin (5-ht) and its receptors in the dendrite formation of purkinje cells in organotypic cultures of anterior and posterior lobes of the cerebellum at postnatal day 7. |
2004-04-12 |
2023-08-12 |
rat |
| Gabriella Sekerková, Ema Ilijic, Enrico Mugnain. Bromodeoxyuridine administered during neurogenesis of the projection neurons causes cerebellar defects in rat. The Journal of comparative neurology. vol 470. issue 3. 2004-04-09. PMID:14755513. |
we demonstrate that this treatment effectively labeled distinct cerebellar cell populations but produced striking defects in the proliferation, migration, and settling of the purkinje cells; reduced the size of the cerebellar cortex and nuclei; produced defects in the patterning of foliation; and also affected litter size, body weight, and mortality of the offspring. |
2004-04-09 |
2023-08-12 |
rat |
| D H Shin, K-S Lee, E Lee, Y P Chang, J-W Kim, Y S Choi, B-S Kwon, H W Lee, S S Ch. Pax-7 immunoreactivity in the post-natal chicken central nervous system. Anatomia, histologia, embryologia. vol 32. issue 6. 2004-04-08. PMID:14651488. |
on the contrary, in the cerebellum, pax-7 was mainly localized within the bergmann glia, whereas purkinje cells did not show any irs. |
2004-04-08 |
2023-08-12 |
chicken |
| Anna R Taylor, Ronald W Oppenhei. The kiss of death. Neuron. vol 41. issue 4. 2004-03-30. PMID:14980198. |
a recent study by marín-teva et al., in this issue of neuron, brings this theory into question and suggests that neighboring microglia actively participate in the pcd of purkinje cells in the cerebellum. |
2004-03-30 |
2023-08-12 |
Not clear |
| José Luis Marín-Teva, Isabelle Dusart, Catherine Colin, Annie Gervais, Nico van Rooijen, Michel Malla. Microglia promote the death of developing Purkinje cells. Neuron. vol 41. issue 4. 2004-03-30. PMID:14980203. |
in the developing mouse cerebellum, purkinje cells die, and 60% of these neurons that already expressed activated caspase-3 were engulfed or contacted by spreading processes emitted by microglial cells. |
2004-03-30 |
2023-08-12 |
mouse |
| José Luis Marín-Teva, Isabelle Dusart, Catherine Colin, Annie Gervais, Nico van Rooijen, Michel Malla. Microglia promote the death of developing Purkinje cells. Neuron. vol 41. issue 4. 2004-03-30. PMID:14980203. |
apoptosis of purkinje cells in cerebellar slices was strongly reduced by selective elimination of microglia. |
2004-03-30 |
2023-08-12 |
mouse |
| H H L M Goossens, F E Hoebeek, A M Van Alphen, J Van Der Steen, J S Stahl, C I De Zeeuw, M A Fren. Simple spike and complex spike activity of floccular Purkinje cells during the optokinetic reflex in mice lacking cerebellar long-term depression. The European journal of neuroscience. vol 19. issue 3. 2004-03-29. PMID:14984419. |
simple spike and complex spike activity of floccular purkinje cells during the optokinetic reflex in mice lacking cerebellar long-term depression. |
2004-03-29 |
2023-08-12 |
mouse |