| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephen G Waxma. Axonal conduction and injury in multiple sclerosis: the role of sodium channels. Nature reviews. Neuroscience. vol 7. issue 12. 2007-01-23. PMID:17115075. |
recent studies have implicated specific sodium channel isoforms as having an important role in several aspects of the pathophysiology of ms, including the restoration of impulse conduction after demyelination, axonal degeneration and the mistuning of purkinje neurons that leads to cerebellar dysfunction. |
2007-01-23 |
2023-08-12 |
Not clear |
| Ulrich Schüller, Alvin T Kho, Qing Zhao, Qiufu Ma, David H Rowitc. Cerebellar 'transcriptome' reveals cell-type and stage-specific expression during postnatal development and tumorigenesis. Molecular and cellular neurosciences. vol 33. issue 3. 2007-01-16. PMID:16962790. |
we used a library of approximately 1100 probes for expression of transcription factor (tf)-encoding genes (>70% of the mammalian 'transcriptome') to identify 227 genes with expression in developing neuronal and glial populations and 24 tfs that show cell-type- and stage-specific expression in granule cells, purkinje cells and interneurons during postnatal cerebellar development. |
2007-01-16 |
2023-08-12 |
Not clear |
| Ulrike Brandt-Bohne, Douglas R Keene, Fletcher A White, Manuel Koc. MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system. The Biochemical journal. vol 401. issue 2. 2007-01-16. PMID:16981854. |
to study the expression pattern further, immunohistochemistry was performed and staining was detected in purkinje cells of the cerebellum and in glial cells of the pns. |
2007-01-16 |
2023-08-12 |
Not clear |
| Dong Liang Ma, Shwn Chin Chia, Yong Cheng Tang, May Ling Joyce Chang, Alphonse Probst, Jean-Marc Burgunder, Feng Ru Tan. Spastin in the human and mouse central nervous system with special reference to its expression in the hippocampus of mouse pilocarpine model of status epilepticus and temporal lobe epilepsy. Neurochemistry international. vol 49. issue 7. 2007-01-05. PMID:16828199. |
in the present in situ hybridization and immunocytochemical studies in the mouse central nervous system (cns), a strong expression of spastin mrna and protein was found in purkinje cells and dentate nucleus in the cerebellum, in hippocampal principal cells and hilar neurons, in amygdala, substantia nigra, striatum, in the motor nuclei of the cranial nerves and in different layers of the cerebral cortex except piriform and entorhinal cortices where only neurons in layer ii were strongly stained. |
2007-01-05 |
2023-08-12 |
mouse |
| Manuela Marcoli, Guido Maura, Chiara Cervetto, Caterina Giacomini, Diana Oliveri, Simona Candiani, Mario Pestarin. Nitric oxide-evoked cGMP production in Purkinje cells in rat cerebellum: an immunocytochemical and pharmacological study. Neurochemistry international. vol 49. issue 7. 2007-01-05. PMID:16904241. |
nitric oxide-evoked cgmp production in purkinje cells in rat cerebellum: an immunocytochemical and pharmacological study. |
2007-01-05 |
2023-08-12 |
rat |
| Georgia A Bishop, Jin Bin Tian, Jennifer J Stanke, Andy J Fischer, James S Kin. Evidence for the presence of the type 2 corticotropin releasing factor receptor in the rodent cerebellum. Journal of neuroscience research. vol 84. issue 6. 2007-01-04. PMID:16955482. |
neuronal labeling is present in sub-populations of purkinje cells, golgi cells, basket cells, and cerebellar nuclear neurons. |
2007-01-04 |
2023-08-12 |
Not clear |
| Georgia A Bishop, Jin Bin Tian, Jennifer J Stanke, Andy J Fischer, James S Kin. Evidence for the presence of the type 2 corticotropin releasing factor receptor in the rodent cerebellum. Journal of neuroscience research. vol 84. issue 6. 2007-01-04. PMID:16955482. |
the present results confirm that crf-r2alpha is present in the cerebellum and functions in circuits that modulate the firing rate of purkinje cells and cerebellar nuclear neurons. |
2007-01-04 |
2023-08-12 |
Not clear |
| Wei-Jung A Chen, Karen A King, Ruby E Lee, Christopher S Sedtal, Andrew M Smit. Effects of nicotine exposure during prenatal or perinatal period on cell numbers in adult rat hippocampus and cerebellum: a stereology study. Life sciences. vol 79. issue 23. 2006-12-21. PMID:16959275. |
the present study examined the long-term effects of early nicotine exposure on the number of pyramidal and granule cells in the hippocampus, and purkinje cells in the cerebellar vermis. |
2006-12-21 |
2023-08-12 |
rat |
| L Bruschini, P Andre, O Pompeiano, D Manzon. Responses of Purkinje-cells of the cerebellar anterior vermis to stimulation of vestibular and somatosensory receptors. Neuroscience. vol 142. issue 1. 2006-12-20. PMID:16843608. |
in order to better understand the mechanisms of these phenomena, the simple spike activity of purkinje (p-) cells was recorded from the vermal cortex of the cerebellar anterior lobe during individual and/or combined stimulation of somatosensory wrist, neck and vestibular receptors. |
2006-12-20 |
2023-08-12 |
cat |
| E Bahn, S Siegert, T Pfander, M L Kramer, W J Schulz-Schaeffer, J W Hewett, X O Breakefield, J C Hedreen, K M Rostás. TorsinB expression in the developing human brain. Brain research. vol 1116. issue 1. 2006-12-12. PMID:16938275. |
expression of torsinb protein was detectable beginning at four to 8 weeks of age in the cerebellum (purkinje cells), substantia nigra (dopaminergic neurons), hippocampus and basal ganglia and was predominantly restricted to neuronal cells. |
2006-12-12 |
2023-08-12 |
human |
| Yukiteru Maeda, Lisa Fujimura, Jiyang O-Wang, Masahiko Hatano, Akemi Sakamoto, Masafumi Arima, Masaaki Ebara, Hidetoshi Ino, Toshihide Yamashita, Hiromitsu Saisho, Takeshi Tokuhis. Role of Clast1 in development of cerebellar granule cells. Brain research. vol 1104. issue 1. 2006-11-30. PMID:16814752. |
the clast1-ko cerebellum with ataxia is small in size and revealed a severely aberrant lobulation, loss of the internal granule cell layer, and the disorganized purkinje cells. |
2006-11-30 |
2023-08-12 |
mouse |
| Rashmi Sisodia, Seema Kumari, Rajesh Kumar Verma, A L Bhati. Prophylactic role of melatonin against radiation induced damage in mouse cerebellum with special reference to Purkinje cells. Journal of radiological protection : official journal of the Society for Radiological Protection. vol 26. issue 2. 2006-11-28. PMID:16738418. |
prophylactic role of melatonin against radiation induced damage in mouse cerebellum with special reference to purkinje cells. |
2006-11-28 |
2023-08-12 |
mouse |
| Rashmi Sisodia, Seema Kumari, Rajesh Kumar Verma, A L Bhati. Prophylactic role of melatonin against radiation induced damage in mouse cerebellum with special reference to Purkinje cells. Journal of radiological protection : official journal of the Society for Radiological Protection. vol 26. issue 2. 2006-11-28. PMID:16738418. |
the present study is an attempt to investigate the prophylactic influence of a chronic low level of melatonin against an acute radiation induced oxidative stress in the cerebellum of swiss albino mice, with special reference to purkinje cells. |
2006-11-28 |
2023-08-12 |
mouse |
| Arundhati Ray, Georg Zoidl, Petra Wahle, Rolf Dermietze. Pannexin expression in the cerebellum. Cerebellum (London, England). vol 5. issue 3. 2006-11-28. PMID:16997749. |
although the functional relevance of these molecules remains currently unknown, the abundance of pannexins in the purkinje cells suggests that they may contribute to the generation of cerebellar rhythms. |
2006-11-28 |
2023-08-12 |
mouse |
| Rosemarie Drake-Bauman. Activity-dependent modulation of inhibition in Purkinje cells by TrkB ligands. Cerebellum (London, England). vol 5. issue 3. 2006-11-28. PMID:16997754. |
in the cerebellum in vitro trkb receptor ligands promote activity-dependent inhibitory synaptogenesis of purkinje cells and also modulate inhibitory synaptic function. |
2006-11-28 |
2023-08-12 |
Not clear |
| Shin-Ya Saito, Hiroshi Takeshim. DNER as key molecule for cerebellar maturation. Cerebellum (London, England). vol 5. issue 3. 2006-11-28. PMID:16997755. |
in the cerebellum, dner is abundantly expressed in purkinje cells and moderately in granule cells. |
2006-11-28 |
2023-08-12 |
mouse |
| Shin-Ya Saito, Hiroshi Takeshim. DNER as key molecule for cerebellar maturation. Cerebellum (London, England). vol 5. issue 3. 2006-11-28. PMID:16997755. |
the mutant cerebellum showed morphological impairments of bergmann glia and multiple innervation between climbing fibers and purkinje cells. |
2006-11-28 |
2023-08-12 |
mouse |
| Shin-Ya Saito, Hiroshi Takeshim. DNER as key molecule for cerebellar maturation. Cerebellum (London, England). vol 5. issue 3. 2006-11-28. PMID:16997755. |
moreover, glutamate clearance at the synapses between parallel fibers and purkinje cells was significantly weakened, and the expression of glast, a glutamate transporter in bergmann glia, was reduced in the mutant cerebellum. |
2006-11-28 |
2023-08-12 |
mouse |
| Gilles Tournel, Anne Bécart-Robert, Philippe Courtin, Valéry Hédouin, Didier Gosse. Fatal accidental intrathecal injection of vindesine. Journal of forensic sciences. vol 51. issue 5. 2006-11-22. PMID:17018103. |
the brain was edematous and, in the cerebellum, the vermis showed a loss of granule and purkinje cells. |
2006-11-22 |
2023-08-12 |
Not clear |
| Jana Boy, Trygve B Leergaard, Thorsten Schmidt, Francis Odeh, Ulrike Bichelmeier, Silke Nuber, Carsten Holzmann, Andreas Wree, Stanley B Prusiner, Hermann Bujard, Olaf Riess, Jan G Bjaali. Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models. NeuroImage. vol 33. issue 2. 2006-11-21. PMID:16931059. |
among the ensuing results were expression of this promoter in putative glial cells in the cerebellum (and not in purkinje cells), in putative glial cells in the substantia nigra, in pallidal glial cells or interneurons, and in distinct cell layers and regions of the hippocampus. |
2006-11-21 |
2023-08-12 |
mouse |