| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bruce E McKay, Jordan D T Engbers, W Hamish Mehaffey, Grant R J Gordon, Michael L Molineux, Jaideep S Bains, Ray W Turne. Climbing fiber discharge regulates cerebellar functions by controlling the intrinsic characteristics of purkinje cell output. Journal of neurophysiology. vol 97. issue 4. 2007-07-10. PMID:17267759. |
the contribution of purkinje cells to cerebellar motor coordination and learning is determined in part by the chronic and acute effects of climbing fiber (cf) afferents. |
2007-07-10 |
2023-08-12 |
rat |
| Jiangang Gao, Stéphane F Maison, Xudong Wu, Keiko Hirose, Sherri M Jones, Ildar Bayazitov, Yong Tian, Guy Mittleman, Douglas B Matthews, Stanislav S Zakharenko, M Charles Liberman, Jian Zu. Orphan glutamate receptor delta1 subunit required for high-frequency hearing. Molecular and cellular biology. vol 27. issue 12. 2007-07-09. PMID:17438141. |
glurdelta2 is expressed exclusively in the purkinje cells of the cerebellum, and glurdelta1 is prominently expressed in inner ear hair cells and neurons of the hippocampus. |
2007-07-09 |
2023-08-12 |
mouse |
| Junko Kimura-Kuroda, Isao Nagata, Yoichiro Kurod. Disrupting effects of hydroxy-polychlorinated biphenyl (PCB) congeners on neuronal development of cerebellar Purkinje cells: a possible causal factor for developmental brain disorders? Chemosphere. vol 67. issue 9. 2007-06-27. PMID:17223178. |
previously, we reported that ths are essential for neuronal development and the low doses of two oh-pcbs, namely, 4-oh-2',3,3',4',5'-pentachlorobiphenyl (4'-oh-pecb-106) and 4-oh-2',3,3',4',5,5'-hexachlorobiphenyl (4'-oh-hxcb-159), inhibited the th-dependent dendritic development of purkinje cells in mouse cerebellar cultures using serum-free defined medium. |
2007-06-27 |
2023-08-12 |
mouse |
| Giovanni Frisullo, Giacomo Della Marca, Massimiliano Mirabella, Marcella Caggiula, Aldobrando Broccolini, Marco Rubino, Gioacchino Mennuni, Pietro Attilio Tonali, Anna Paola Batocch. A human anti-neuronal autoantibody against GABA B receptor induces experimental autoimmune agrypnia. Experimental neurology. vol 204. issue 2. 2007-06-26. PMID:17336294. |
immunohistochemistry on brain sections of mice injected with patient igg showed the simultaneous presence of bound human igg and c5b-9 deposits on purkinje cells and cerebellar granular layer. |
2007-06-26 |
2023-08-12 |
mouse |
| Kazuhisa Kohda, Wataru Kakegawa, Shinji Matsuda, Ryoichi Nakagami, Naomasa Kakiya, Michisuke Yuzak. The extreme C-terminus of GluRdelta2 is essential for induction of long-term depression in cerebellar slices. The European journal of neuroscience. vol 25. issue 5. 2007-06-25. PMID:17425562. |
in this study, we developed a virus vector-based gene transfer approach to rescue impaired ltd in glurdelta2-null purkinje cells in cerebellar slice preparations. |
2007-06-25 |
2023-08-12 |
Not clear |
| Stephanie Arndt, Ina Poser, Markus Moser, Anja-Katrin Bosserhof. Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling. Molecular and cellular neurosciences. vol 34. issue 4. 2007-06-22. PMID:17292623. |
interestingly, fussel-15 expression is even more restricted in adulthood to purkinje cells of human cerebellum. |
2007-06-22 |
2023-08-12 |
mouse |
| Rhea R Kimpo, Jennifer L Raymon. Impaired motor learning in the vestibulo-ocular reflex in mice with multiple climbing fiber input to cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 21. 2007-06-22. PMID:17522312. |
a unique feature of the cerebellar architecture is that purkinje cells in the cerebellar cortex each receive input from a single climbing fiber. |
2007-06-22 |
2023-08-12 |
mouse |
| Rhea R Kimpo, Jennifer L Raymon. Impaired motor learning in the vestibulo-ocular reflex in mice with multiple climbing fiber input to cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 21. 2007-06-22. PMID:17522312. |
together, the results suggest that single climbing fiber innervation of purkinje cells is critical for some, but not all, forms of cerebellum-dependent learning, and this may depend on the region of the cerebellum involved, the organization of the relevant neural circuits downstream of the cerebellar cortex, as well as the timing requirements of the learning task. |
2007-06-22 |
2023-08-12 |
mouse |
| Chen-Jei Hong, Yi-Ping Hsue. Cytoplasmic distribution of T-box transcription factor Tbr-1 in adult rodent brain. Journal of chemical neuroanatomy. vol 33. issue 3. 2007-06-18. PMID:17329080. |
in the cerebellum of p15, p22, and adult rats, tbr-1 was specifically expressed in purkinje cells, where tbr-1 was localised in the cytoplasm, including the dendritic tree. |
2007-06-18 |
2023-08-12 |
rat |
| Ying Wang, Jiali Liu, Elizabeth Smith, Kang Zhou, Jie Liao, Guang-Yu Yang, Ming Tan, Xi Zha. Downregulation of missing in metastasis gene (MIM) is associated with the progression of bladder transitional carcinomas. Cancer investigation. vol 25. issue 2. 2007-06-14. PMID:17453818. |
immunohistochemical staining of adult mouse tissues revealed abundant mim immunoreactivity in uroepithelial cells in the bladder, neuron purkinje cells in the cerebellum, and megakaryocytes in the bone marrow and spleen in addition. |
2007-06-14 |
2023-08-12 |
mouse |
| Sanjay S Kumar, Paul S Buckmaste. Neuron-specific nuclear antigen NeuN is not detectable in gerbil subtantia nigra pars reticulata. Brain research. vol 1142. 2007-06-13. PMID:17291468. |
some notable exceptions (i.e., neun-negative neurons) include purkinje cells in cerebellum, mitral cells in olfactory bulb, and photoreceptors in retina. |
2007-06-13 |
2023-08-12 |
rat |
| Akihiko S Kato, Wei Zhou, Aaron D Milstein, Mike D Knierman, Edward R Siuda, Joe E Dotzlaf, Hong Yu, John E Hale, Eric S Nisenbaum, Roger A Nicoll, David S Bred. New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 18. 2007-06-06. PMID:17475805. |
western blotting reveals high levels of gamma-5 and gamma-7 in the cerebellum, where gamma-7 is enriched in purkinje neurons in the molecular layer and glomerular synapses in the granule cell layer. |
2007-06-06 |
2023-08-12 |
mouse |
| Yukun Yuan, William D Atchiso. Methylmercury-induced increase of intracellular Ca2+ increases spontaneous synaptic current frequency in rat cerebellar slices. Molecular pharmacology. vol 71. issue 4. 2007-06-04. PMID:17244699. |
the relationship between increased intracellular calcium concentration ([ca(2+)](i)) and changes in spontaneous synaptic current frequency caused by the neurotoxicant methylmercury (mehg) was examined in purkinje cells of cerebellar slices using confocal microscopy and whole-cell recording. |
2007-06-04 |
2023-08-12 |
rat |
| Volker Steuber, Wolfgang Mittmann, Freek E Hoebeek, R Angus Silver, Chris I De Zeeuw, Michael Häusser, Erik De Schutte. Cerebellar LTD and pattern recognition by Purkinje cells. Neuron. vol 54. issue 1. 2007-06-01. PMID:17408582. |
cerebellar ltd and pattern recognition by purkinje cells. |
2007-06-01 |
2023-08-12 |
mouse |
| Volker Steuber, Wolfgang Mittmann, Freek E Hoebeek, R Angus Silver, Chris I De Zeeuw, Michael Häusser, Erik De Schutte. Cerebellar LTD and pattern recognition by Purkinje cells. Neuron. vol 54. issue 1. 2007-06-01. PMID:17408582. |
many theories of cerebellar function assume that long-term depression (ltd) of parallel fiber (pf) synapses enables purkinje cells to learn to recognize pf activity patterns. |
2007-06-01 |
2023-08-12 |
mouse |
| Teresa K Aman, Indira M Rama. Subunit dependence of Na channel slow inactivation and open channel block in cerebellar neurons. Biophysical journal. vol 92. issue 6. 2007-05-16. PMID:17189307. |
purkinje and cerebellar nuclear neurons both have na currents with resurgent kinetics. |
2007-05-16 |
2023-08-12 |
mouse |
| Teresa K Aman, Indira M Rama. Subunit dependence of Na channel slow inactivation and open channel block in cerebellar neurons. Biophysical journal. vol 92. issue 6. 2007-05-16. PMID:17189307. |
to compare fast inactivation, slow inactivation, and open-channel block, we recorded voltage-clamped, tetrodotoxin-sensitive na currents in purkinje and nuclear neurons acutely isolated from mouse cerebellum. |
2007-05-16 |
2023-08-12 |
mouse |
| Jae-Sung Bae, Hyung Soo Han, Dong-Ho Youn, Janet E Carter, Michel Modo, Edward H Schuchman, Hee Kyung Ji. Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration. Stem cells (Dayton, Ohio). vol 25. issue 5. 2007-05-16. PMID:17470534. |
to address the mechanism by which this occurs, we used gene microarray, whole-cell patch-clamp recordings, and immunohistochemistry to evaluate expression of neurotransmitter receptors on purkinje neurons in the np-c cerebellum. |
2007-05-16 |
2023-08-12 |
mouse |
| Takashi Shiihara, Mitsuhiro Kato, Akihiro Konno, Yukitoshi Takahashi, Kiyoshi Hayasak. Acute cerebellar ataxia and consecutive cerebellitis produced by glutamate receptor delta2 autoantibody. Brain & development. vol 29. issue 4. 2007-05-15. PMID:17049194. |
glutamate receptor delta2, a member of the glutamate receptor family, is predominantly expressed in cerebellar purkinje cells and plays a crucial role in cerebellar functions. |
2007-05-15 |
2023-08-12 |
Not clear |
| Yelda Serinagaoglu, Rui Zhang, Yufang Zhang, Linda Zhang, Greg Hartt, Anthony P Young, John Oberdic. A promoter element with enhancer properties, and the orphan nuclear receptor RORalpha, are required for Purkinje cell-specific expression of a Gi/o modulator. Molecular and cellular neurosciences. vol 34. issue 3. 2007-05-15. PMID:17215137. |
thus, in addition to its recently indicated role in ca2+-mediated reciprocal cell-cell signaling in purkinje cells, roralpha may also contribute to functional differences in cerebellar subregions. |
2007-05-15 |
2023-08-12 |
mouse |