| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Avella, M B Pisu, E Roda, M Gravati, G Bernocch. Reorganization of the rat cerebellar cortex during postnatal development following cisplatin treatment. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16806181. |
since knowledge of the parallel and climbing fiber-purkinje cell system is important in order to determine the architectural basis of cerebellar function, we used immunofluorescence for vesicular glutamate transporters (vglut1 and vglut2) to evaluate the trend of synaptogenesis of parallel and climbing fibers on purkinje cells in the cerebellum vermis after a single injection of cisplatin to 10-day-old rats, i.e., during a crucial period of cerebellar development. |
2006-11-14 |
2023-08-12 |
rat |
| Stephen I Levin, Zayd M Khaliq, Teresa K Aman, Tina M Grieco, Jennifer A Kearney, Indira M Raman, Miriam H Meisle. Impaired motor function in mice with cell-specific knockout of sodium channel Scn8a (NaV1.6) in cerebellar purkinje neurons and granule cells. Journal of neurophysiology. vol 96. issue 2. 2006-11-08. PMID:16687615. |
to test the effect of cerebellar na(v)1.6 on motor coordination in mice, we used the cre-lox system to eliminate scn8a expression exclusively in purkinje neurons (purkinje ko) and/or granule neurons (granule ko). |
2006-11-08 |
2023-08-12 |
mouse |
| Stephen I Levin, Zayd M Khaliq, Teresa K Aman, Tina M Grieco, Jennifer A Kearney, Indira M Raman, Miriam H Meisle. Impaired motor function in mice with cell-specific knockout of sodium channel Scn8a (NaV1.6) in cerebellar purkinje neurons and granule cells. Journal of neurophysiology. vol 96. issue 2. 2006-11-08. PMID:16687615. |
in cerebellar slices, purkinje cell spontaneous and maximal firing rates were reduced 10-fold and twofold relative to control in purkinje ko and double ko but not granule ko mice. |
2006-11-08 |
2023-08-12 |
mouse |
| Christian Hansel, Marcel de Jeu, Amor Belmeguenai, Simone H Houtman, Gabriëlle H S Buitendijk, Dmitri Andreev, Chris I De Zeeuw, Ype Elgersm. alphaCaMKII Is essential for cerebellar LTD and motor learning. Neuron. vol 51. issue 6. 2006-11-07. PMID:16982427. |
since purkinje cells are the only cells in the cerebellum that express alphacamkii, our data suggest that an impairment of parallel fiber ltd, while leaving ltp intact, is sufficient to disrupt this form of cerebellar learning. |
2006-11-07 |
2023-08-12 |
mouse |
| Mario Carta, Luca Murru, Paolo Botta, Giuseppe Talani, GianPietro Sechi, PierLuigi De Riu, Enrico Sanna, Giovanni Biggi. The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. Neuropharmacology. vol 51. issue 4. 2006-11-06. PMID:16806306. |
we now show that the phasic and tonic gabaar-mediated currents recorded from purkinje cells and granule neurons, respectively, in parasagittal cerebellar slices from adult male rats were inhibited by tcc in a concentration-dependent manner. |
2006-11-06 |
2023-08-12 |
rat |
| Yong-Hwan Kim, Jamie Peregrine, Arthur P Arnol. The distribution of expression of doublecortin (DCX) mRNA and protein in the zebra finch brain. Brain research. vol 1106. issue 1. 2006-11-01. PMID:16814268. |
in adult brain, dcx mrna was detected mainly in the mesopallium (m), medial striatum (mst), septum, area x, diencephalon, telencephalic subventricular zone (svz), and purkinje cells in the cerebellum. |
2006-11-01 |
2023-08-12 |
Not clear |
| Yong-Hwan Kim, Jamie Peregrine, Arthur P Arnol. The distribution of expression of doublecortin (DCX) mRNA and protein in the zebra finch brain. Brain research. vol 1106. issue 1. 2006-11-01. PMID:16814268. |
outside of the telencephalon at p9, we found distinct label in nucleus ovoidalis (ov), nucleus spiriformis lateralis (spl), and nucleus subpretectalis (sp) in the midbrain, almost the entire diencephalon including nucleus dorsomedialis posterior thalami (dmp), stratum griseum et fibrosum superficiale (sgf) in optic tectum, and purkinje cells in cerebellum. |
2006-11-01 |
2023-08-12 |
Not clear |
| Aryn H Gittis, Sascha du La. Intrinsic and synaptic plasticity in the vestibular system. Current opinion in neurobiology. vol 16. issue 4. 2006-11-01. PMID:16842990. |
learning in the vestibulo-ocular reflex depends initially on the activity of purkinje cells in the cerebellar flocculus, but consolidated memories appear to be stored downstream of purkinje cells, probably in the vestibular nuclei. |
2006-11-01 |
2023-08-12 |
Not clear |
| V Ia Karmysheva, V V Pogodin. [Prionic neuroinvasion and cerebellar lesion in Creutzfeldt-Jakob disease]. Arkhiv patologii. vol 68. issue 4. 2006-10-31. PMID:16986493. |
in sporadic cjd, prp(cjd) accumulated only in the cerebellar molecular layer in the area of the synapses formed by climbing fibers with the dendrites of purkinje cells. |
2006-10-31 |
2023-08-12 |
Not clear |
| S Joshua Langmade, Sarah E Gale, Andrey Frolov, Ikuko Mohri, Kinuko Suzuki, Synthia H Mellon, Steven U Walkley, Douglas F Covey, Jean E Schaffer, Daniel S Or. Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 37. 2006-10-30. PMID:16940355. |
allo and t0901317 therapy preserved purkinje cells, suppressed cerebellar expression of microglial-associated genes and inflammatory mediators, and reduced infiltration of activated microglia in the cerebellar tissue. |
2006-10-30 |
2023-08-12 |
mouse |
| Chi-ming Huang, Holly Miyamoto, Rosa H Huan. The mouse cerebellum from 1 to 34 months: parallel fibers. Neurobiology of aging. vol 27. issue 11. 2006-10-26. PMID:16257475. |
in the cerebellum, synapses between the parallel fibers and purkinje cells are strategic elements of its neuronal circuitry. |
2006-10-26 |
2023-08-12 |
mouse |
| Peter Gerke, Thomas Benzing, Martin Höhne, Andreas Kispert, Michael Frotscher, Gerd Walz, Oliver Kret. Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis. The Journal of comparative neurology. vol 498. issue 4. 2006-10-25. PMID:16874800. |
in the adult brain, neph1 and neph2 are predominantly seen in the olfactory nerve layer and the glomerular layer of the olfactory bulb, in the hippocampus, and in purkinje cells of the cerebellum. |
2006-10-25 |
2023-08-12 |
mouse |
| Yoshihisa Takiyam. Autosomal recessive spastic ataxia of Charlevoix-Saguenay. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 26. issue 4. 2006-10-25. PMID:16961075. |
the principal neuropathology comprises atrophy of the upper vermis and the loss of purkinje cells in the cerebellum. |
2006-10-25 |
2023-08-12 |
Not clear |
| Amy Alessi, April D Bragg, Justin M Percival, Jean Yoo, Douglas E Albrecht, Stanley C Froehner, Marvin E Adam. gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins. Experimental cell research. vol 312. issue 16. 2006-10-24. PMID:16857187. |
gamma1-syntrophin is highly expressed in brain and is specifically localized in hippocampal pyramidal neurons, purkinje neurons in cerebellum, and cortical neurons. |
2006-10-24 |
2023-08-12 |
mouse |
| Tetsushi Sadakata, Teiichi Furuich. Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain. Neuroscience letters. vol 405. issue 3. 2006-10-24. PMID:16901643. |
c1502/qp-c mrna was localized at high levels in the olfactory bulb, cerebral cortex, hippocampus, thalamus (anterodorsal nucleus, parafacicularis nucleus), tegmentum (red nucleus), cerebellum (purkinje and granule cells), and pons (pontine nucleus, reticulotegmental nucleus, trapezoid body, vestibular nucleus). |
2006-10-24 |
2023-08-12 |
mouse |
| Magdalena Spiechowicz, Hans-Gert Bernstein, Henrik Dobrowolny, Wiesława Leśniak, Christian Mawrin, Bernhard Bogerts, Jacek Kuźnicki, Anna Filipe. Density of Sgt1-immunopositive neurons is decreased in the cerebral cortex of Alzheimer's disease brain. Neurochemistry international. vol 49. issue 5. 2006-10-18. PMID:16698122. |
in normal brain we observed sgt1-immunostaining in purkinje cells of the cerebellum, in granule cells of the dentate gyrus of the hippocampus and in multiple neurons of the cortex. |
2006-10-18 |
2023-08-12 |
human |
| K Qin, L Zhao, Y Tang, S Bhatta, J M Simard, R Y Zha. Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes. Neuroscience. vol 141. issue 3. 2006-10-18. PMID:16766127. |
expression of a prion-like protein, doppel, induces apoptosis-like changes in cerebellar neuronal granule and purkinje cells of prion-knockout mice and this effect can be rescued by re-introduction of cellular prion. |
2006-10-18 |
2023-08-12 |
mouse |
| A Blanco, R Moyano, J Vivo, R Flores-Acuña, A Molina, C Blanco, J G Monterd. Purkinje cell apoptosis in arabian horses with cerebellar abiotrophy. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 53. issue 6. 2006-10-10. PMID:16901270. |
purkinje cerebellar cells were studied in three arabian horses aged between 6 and 8 months with clinical disorders in their movements, tremors and ataxia; the occurrence of apoptosis in this cell population was investigated by the (terminal deoxynucleotidyl transferase biotin-dutp nick-end labelling (tunel) method. |
2006-10-10 |
2023-08-12 |
Not clear |
| Sudong Guan, Shanfeng Ma, Yan Zhu, Jinhui Wan. The postnatal development of refractory periods and threshold potentials at cerebellar Purkinje neurons. Brain research. vol 1097. issue 1. 2006-10-06. PMID:16730670. |
cerebellum is involved in the motion coordination and working memory, to which spike programming at purkinje neurons are essential. |
2006-10-06 |
2023-08-12 |
Not clear |
| Sudong Guan, Shanfeng Ma, Yan Zhu, Jinhui Wan. The postnatal development of refractory periods and threshold potentials at cerebellar Purkinje neurons. Brain research. vol 1097. issue 1. 2006-10-06. PMID:16730670. |
we developed the approach to quantify the intrinsic property of sequential spikes with whole-cell recording, and analyzed the postnatal development of purkinje neurons in cerebellar slices. |
2006-10-06 |
2023-08-12 |
Not clear |