| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheryl A Hawkes, LeHua Deng, Daniela Fenili, Mark Nitz, JoAnne McLauri. In vivo uptake of β-amyloid by non-plaque associated microglia. Current Alzheimer research. vol 9. issue 8. 2013-06-21. PMID:22272621. |
we report here the identification of aβ-positive processes throughout the cortex and hippocampus of tgcrnd8 mice expressing the human swedish (km670/671nl) and indiana (v717f) amyloid precursor protein mutations, which localized to ionized calcium binding protein-1-positive resident microglia that were not associated with extracellular plaques. |
2013-06-21 |
2023-08-12 |
mouse |
| Honghong Yao, Ming Duan, Lu Yang, Shilpa Buc. Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of β1 integrins. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 4. 2013-06-17. PMID:23292072. |
in vivo corroboration of these findings demonstrated decreased migration of nmmylk(-/-) microglia (2 × 10(5) cells transplanted into corpus callosum) compared with wt microglia toward microinjected tat₁₋₇₂ (2 μg/mouse) in hippocampus. |
2013-06-17 |
2023-08-12 |
mouse |
| Fei Gao, Yangfeng Liu, Xiaowei Li, Ying Wang, Dong Wei, Wen Jian. Fingolimod (FTY720) inhibits neuroinflammation and attenuates spontaneous convulsions in lithium-pilocarpine induced status epilepticus in rat model. Pharmacology, biochemistry, and behavior. vol 103. issue 2. 2013-06-11. PMID:22960129. |
we found that fty720 treatment reduced neuronal loss and decreased activation of microglia and astrocytes in hippocampus at four days post-se. |
2013-06-11 |
2023-08-12 |
rat |
| Miyoung Yang, Juhwan Kim, Taehyub Kim, Sung-Ho Kim, Jong-Choon Kim, Jeongtae Kim, Chitoshi Takayama, Akinobu Hayashi, Hong-Gu Joo, Taekyun Shin, Changjong Moo. Possible involvement of galectin-3 in microglial activation in the hippocampus with trimethyltin treatment. Neurochemistry international. vol 61. issue 7. 2013-06-05. PMID:23063466. |
the immunoreactivity was detected predominantly in most of the iba1-positive microglia and in some gfap-positive astrocytes of the hippocampal dg. |
2013-06-05 |
2023-08-12 |
mouse |
| Hikmet F Nural-Guvener, Nezahet Mutlu, Mohamed A Gaball. BACE1 levels are elevated in congestive heart failure. Neuroscience letters. vol 532. 2013-05-30. PMID:23127855. |
to address this issue, we investigated microglia activation; levels of bace1, the key rate-limiting enzyme involved in the pathogenesis of ad; and vegf levels in the hippocampus and cortex following mi. |
2013-05-30 |
2023-08-12 |
rat |
| Patrick J Cimino, Yue Yang, Xianwu Li, Jake F Hemingway, Makenzie K Cherne, Shawn B Khademi, Yoshinori Fukui, Kathleen S Montine, Thomas J Montine, C Dirk Keen. Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer's disease. Experimental and molecular pathology. vol 94. issue 2. 2013-05-16. PMID:23318649. |
while we found no dock2-dependent differences in cortex or in hippocampal microglia density or morphology in appswe-ps1Δe9 mice, cerebral cortical and hippocampal aβ plaque area and size were significantly reduced in 10-month-old appswe-ps1Δe9/dock2-/- mice compared with appswe-ps1Δe9/dock2+/+ controls. |
2013-05-16 |
2023-08-12 |
mouse |
| Yuliya Borre, Volkan Sir, Sander de Kivit, Koen G Westphal, Berend Olivier, Ronald S Oostin. Minocycline restores spatial but not fear memory in olfactory bulbectomized rats. European journal of pharmacology. vol 697. issue 1-3. 2013-05-02. PMID:23051675. |
here we show that the onset of these cognitive changes parallel in time with signs of microglia activation (increased mrna levels of il-1β and cd68) in hippocampus. |
2013-05-02 |
2023-08-12 |
rat |
| Biao Zhu, Yuanlin Dong, Zhipeng Xu, Heinrich S Gompf, Sarah A P Ward, Zhanggang Xue, Changhong Miao, Yiying Zhang, Nancy L Chamberlin, Zhongcong Xi. Sleep disturbance induces neuroinflammation and impairment of learning and memory. Neurobiology of disease. vol 48. issue 3. 2013-04-30. PMID:22776332. |
sleep disturbance increased pro-inflammatory cytokine il-6 levels and induced microglia activation in the mouse hippocampus, but not the cortex. |
2013-04-30 |
2023-08-12 |
mouse |
| Yanqing Bian, Zhuo Pan, Ziyuan Hou, Cui Huang, Wei Li, Baohua Zha. Learning, memory, and glial cell changes following recovery from chronic unpredictable stress. Brain research bulletin. vol 88. issue 5. 2013-04-25. PMID:22537595. |
immunohistochemical tests revealed that cus-induced alterations in microglia could dissipate with time in the ca3 region of the hippocampus and prelimbic areas. |
2013-04-25 |
2023-08-12 |
mouse |
| M Jafari, V Haist, W Baumgärtner, S Wagner, V M Stein, A Tipold, H Wendt, H Potschk. Impact of Theiler's virus infection on hippocampal neuronal progenitor cells: differential effects in two mouse strains. Neuropathology and applied neurobiology. vol 38. issue 7. 2013-04-24. PMID:22288387. |
therefore, the study aimed to determine the impact of theiler's murine encephalomyelitis virus infection on hippocampal cell proliferation, neuronal progenitor cells and neurogenesis as well as the influence of microglia on respective disease-associated alterations. |
2013-04-24 |
2023-08-12 |
mouse |
| Anthony Lyons, Eric J Downer, Derek A Costello, Niamh Murphy, Marina A Lync. Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia. Journal of neuroinflammation. vol 9. 2013-04-19. PMID:22642833. |
there is evidence of increased activation under resting and stimulated conditions in microglia prepared from cd200-deficient mice compared with wild-type mice, whereas activation of the receptor by cd200 fusion protein (cd200fc) ameliorates inflammatory changes which are evident in the central nervous system (cns) of the mouse model of multiple sclerosis (ms), experimental autoimmune encephalomyelitis (eae) and also in the hippocampus of aged rats. |
2013-04-19 |
2023-08-12 |
mouse |
| Shijie Song, Shuojing Song, Chuanhai Cao, Xiaoyang Lin, Kunyu Li, Vasyl Sava, Juan Sanchez-Ramo. Hippocampal neurogenesis and the brain repair response to brief stereotaxic insertion of a microneedle. Stem cells international. vol 2013. 2013-04-05. PMID:23554817. |
brief stereotaxic insertion and removal of a microneedle into the right hippocampus resulted in (a) significantly increased expression of granulocyte-colony stimulating factor (g-csf), the chemokine mip-1a, and the proinflammatory cytokine il12p40; (b) pronounced activation of microglia and astrocytes; and (c) increase in hippocampal neurogenesis. |
2013-04-05 |
2023-08-12 |
Not clear |
| Li-Ying Liu, Feng Wang, Xia-Yan Zhang, Peng Huang, Yun-Bi Lu, Er-Qing Wei, Wei-Ping Zhan. Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases. PloS one. vol 7. issue 10. 2013-04-02. PMID:23071504. |
here we showed that upon aging, nampt level increased in serum but decreased in brain, decreased in cortex and hippocampus but remained unchanged in cerebellum and striatum in brain, and increased in microglia but likely decreased in neuron. |
2013-04-02 |
2023-08-12 |
Not clear |
| Takahiro Katayama, Hayato Kobayashi, Toshiyuki Okamura, Yuko Yamasaki-Katayama, Tatsuya Kibayashi, Hiroshi Kimura, Keiko Ohsawa, Shinichi Kohsaka, Masabumi Minam. Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase. PloS one. vol 7. issue 7. 2013-03-21. PMID:22815830. |
accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 map kinase. |
2013-03-21 |
2023-08-12 |
mouse |
| Stefan Busse, Mandy Busse, Kolja Schiltz, Hendrik Bielau, Tomasz Gos, Ralf Brisch, Christian Mawrin, Andrea Schmitt, Wolfgang Jordan, Ulf J Müller, Hans-Gert Bernstein, Bernhard Bogerts, Johann Steine. Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations? Brain, behavior, and immunity. vol 26. issue 8. 2013-03-12. PMID:22917959. |
different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations? |
2013-03-12 |
2023-08-12 |
Not clear |
| Udani Ratnayake, Tracey A Quinn, Margie Castillo-Melendez, Hayley Dickinson, David W Walke. Behaviour and hippocampus-specific changes in spiny mouse neonates after treatment of the mother with the viral-mimetic Poly I:C at mid-pregnancy. Brain, behavior, and immunity. vol 26. issue 8. 2013-03-12. PMID:22960545. |
brain histology examined at 1 and 100 days of age revealed significant decreases in reelin, increased gfap expression, and increased numbers of activated microglia, specifically in the hippocampus. |
2013-03-12 |
2023-08-12 |
mouse |
| Bo Yong Choi, Bong Geom Jang, Jin Hee Kim, Bo Eun Lee, Min Sohn, Hong Ki Song, Sang Won Su. Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation. Brain research. vol 1481. 2013-03-05. PMID:22975130. |
microglia activation was detected by cd11b immunohistochemistry in the hippocampus at 1 week after tbi. |
2013-03-05 |
2023-08-12 |
rat |
| Min-Hee Yi, Enji Zhang, Joon Won Kang, Yu Na Shin, Jin Young Byun, Sang-Ha Oh, Je Hoon Seo, Young Ho Lee, Dong Woon Ki. Expression of CD200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus. Brain research. vol 1481. 2013-03-05. PMID:22975132. |
expression of cd200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus. |
2013-03-05 |
2023-08-12 |
mouse |
| Francesca Cerbai, Daniele Lana, Daniele Nosi, Polina Petkova-Kirova, Sandra Zecchi, Holly M Brothers, Gary L Wenk, Maria Grazia Giovannin. The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus. PloS one. vol 7. issue 9. 2013-02-28. PMID:23028880. |
in the hippocampus of aged and lps-treated rats astrocytes and microglia may help clearing apoptotic cellular debris possibly through cx3cl1 signalling. |
2013-02-28 |
2023-08-12 |
rat |
| Francesca Cerbai, Daniele Lana, Daniele Nosi, Polina Petkova-Kirova, Sandra Zecchi, Holly M Brothers, Gary L Wenk, Maria Grazia Giovannin. The neuron-astrocyte-microglia triad in normal brain ageing and in a model of neuroinflammation in the rat hippocampus. PloS one. vol 7. issue 9. 2013-02-28. PMID:23028880. |
our results indicate that astrocytes and microglia in the hippocampus of aged and lps-infused rats possibly participate in the clearance of cellular debris associated with programmed cell death. |
2013-02-28 |
2023-08-12 |
rat |