All Relations between hypertrophic and matrix compartment

Publication Sentence Publish Date Extraction Date Species
G Wol. New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology. European journal of clinical investigation. vol 34. issue 12. 2005-03-14. PMID:15606719. particularly, tgf-beta is important in the development of renal hypertrophy and accumulation of extracellular matrix components. 2005-03-14 2023-08-12 Not clear
G Wol. New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology. European journal of clinical investigation. vol 34. issue 12. 2005-03-14. PMID:15606719. in fact, it has been shown that angiotensin ii is involved in almost every pathophysiological process implicated in the development of diabetic nephropathy (haemodynamic changes, hypertrophy, extracellular matrix accumulation, growth factor/cytokine induction, ros formation, podocyte damage, proteinuria, interstitial inflammation). 2005-03-14 2023-08-12 Not clear
Kotaro Tanimoto, Aya Suzuki, Shigeru Ohno, Koubun Honda, Nobuaki Tanaka, Takeyoshi Doi, Maiko Nakahara-Ohno, Kiyoshi Yoneno, Yuki Nakatani, Masashi Ueki, Tamami Yanagida, Reiko Kitamura, Kazuo Tann. Hyaluronidase expression in cultured growth plate chondrocytes during differentiation. Cell and tissue research. vol 318. issue 2. 2005-03-08. PMID:15503157. the expression levels of hyal1 and hyal2 mrnas were enhanced about 2.8-fold and 3.2-fold at the maximum during the early matrix forming stage, respectively, and by about 3.2-fold and 2.0-fold at the maximum in the hypertrophic stage, respectively. 2005-03-08 2023-08-12 Not clear
Kotaro Tanimoto, Aya Suzuki, Shigeru Ohno, Koubun Honda, Nobuaki Tanaka, Takeyoshi Doi, Maiko Nakahara-Ohno, Kiyoshi Yoneno, Yuki Nakatani, Masashi Ueki, Tamami Yanagida, Reiko Kitamura, Kazuo Tann. Hyaluronidase expression in cultured growth plate chondrocytes during differentiation. Cell and tissue research. vol 318. issue 2. 2005-03-08. PMID:15503157. haase activity was enhanced at the early matrix forming and hypertrophic stages. 2005-03-08 2023-08-12 Not clear
Zihua Zhou, Yu-Hua Liao, Yumiao Wei, Fen Wei, Bin Wang, Liudong Li, Min Wang, Kun Li. Cardiac remodeling after long-term stimulation by antibodies against the alpha1-adrenergic receptor in rats. Clinical immunology (Orlando, Fla.). vol 114. issue 2. 2005-03-08. PMID:15639650. in immunized rats, despite that systolic blood pressure (sbp) had no difference with normal control, the hypertrophy of heart and cardiomyocytes was observed, the collagen deposition in heart interstitium increased, and c-jun expression and matrix metalloproteinase (mmp)-2 mrna expression and activity in heart had increased. 2005-03-08 2023-08-12 rat
Stephane Heymans, Florea Lupu, Sven Terclavers, Bjorn Vanwetswinkel, Jean-Marc Herbert, Andrew Baker, Desire Collen, Peter Carmeliet, Lieve Moon. Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice. The American journal of pathology. vol 166. issue 1. 2005-03-02. PMID:15631996. matrix metalloproteinases (mmps) have been invoked in various cardiac diseases, however, direct genetic evidence for a role of the plasminogen activator (pa) and mmp systems in pressure overload-induced lv hypertrophy and in heart failure is lacking. 2005-03-02 2023-08-12 mouse
Dominique Stickens, Danielle J Behonick, Nathalie Ortega, Babette Heyer, Bettina Hartenstein, Ying Yu, Amanda J Fosang, Marina Schorpp-Kistner, Peter Angel, Zena Wer. Altered endochondral bone development in matrix metalloproteinase 13-deficient mice. Development (Cambridge, England). vol 131. issue 23. 2005-02-22. PMID:15539485. matrix metalloproteinase (mmp) 13 (collagenase 3) is poised to play a crucial role in bone formation and remodeling because of its expression both in terminal hypertrophic chondrocytes in the growth plate and in osteoblasts. 2005-02-22 2023-08-12 mouse
Wilfried Briest, Lars Homagk, Hideo A Baba, Alexander Deten, Beate Rassler, Andrea Tannapfel, Klaus F Wagner, Roland H Wenger, Heinz-Gerd Zimme. Cardiac remodeling in erythropoietin-transgenic mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 14. issue 4-6. 2005-02-15. PMID:15319531. the aim of this study was to examine whether this cardiac dysfunction was accompanied by hypertrophy of the heart with remodeling of the extracellular matrix (ecm). 2005-02-15 2023-08-12 mouse
Denise L Cecil, David M Rose, Robert Terkeltaub, Ru Liu-Brya. Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes. Arthritis and rheumatism. vol 52. issue 1. 2005-02-15. PMID:15641067. moreover, chondrocyte hypertrophy develops in situ in osteoarthritic (oa) articular cartilage and promotes dysregulated matrix repair and calcification. 2005-02-15 2023-08-12 Not clear
S Toyosawa, N Kanatani, S Shintani, M Kobata, M Yuki, M Kishino, N Ijuhin, T Komor. Expression of dentin matrix protein 1 (DMP1) during fracture healing. Bone. vol 35. issue 2. 2005-02-03. PMID:15268908. however, these dmp1-expressing cells were not hypertrophic and were likely to be osteoblast-lineage cells, which were embedded in the matrix of bone or cartilage, because type i collagen-expressing cells and invasion of capillary vessels were observed in the same area. 2005-02-03 2023-08-12 Not clear
Anja Niehoff, Uwe G Kersting, Frank Zaucke, Michael M Morlock, Gert-Peter Brüggeman. Adaptation of mechanical, morphological, and biochemical properties of the rat growth plate to dose-dependent voluntary exercise. Bone. vol 35. issue 4. 2005-02-02. PMID:15454097. osteonectin was located in the matrix of the upper hypertrophic zone in the ue group, whereas the le and con group showed more chondrocytes in the hypertrophic and lower proliferation zones stained for osteonectin, suggesting a higher level of mineralization in the growth plate of the ue group. 2005-02-02 2023-08-12 rat
Fraser D Russel. Emerging roles of urotensin-II in cardiovascular disease. Pharmacology & therapeutics. vol 103. issue 3. 2005-01-28. PMID:15464591. in vitro and in vivo studies show that under pathophysiological conditions, uii might contribute to cardiomyocyte hypertrophy, extracellular matrix production, enhanced vasoconstriction, vascular smooth muscle cell hyperplasia, and endothelial cell hyper-permeability. 2005-01-28 2023-08-12 human
Darren J Kelly, Yuan Zhang, Renae Gow, Richard E Gilber. Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model. Journal of the American Society of Nephrology : JASN. vol 15. issue 10. 2005-01-27. PMID:15466266. tranilast (n-[3,4-dimethoxycinnamoyl] anthranilic acid), an antifibrotic agent that is used to treat hypertrophic scars and scleroderma, has also been shown to inhibit tgf-beta-induced extracellular matrix synthesis in a range of cell types, including those of renal origin. 2005-01-27 2023-08-12 rat
Shona R Elshaw, Neil Henderson, Alan J Knox, Susan A Watson, David J Buttle, Simon R Johnso. Matrix metalloproteinase expression and activity in human airway smooth muscle cells. British journal of pharmacology. vol 142. issue 8. 2005-01-26. PMID:15265805. airway remodelling is a feature of chronic asthma comprising smooth muscle hypertrophy and deposition of extracellular matrix (ecm) proteins. 2005-01-26 2023-08-12 human
Florian Karreth, Astrid Hoebertz, Harald Scheuch, Robert Eferl, Erwin F Wagne. The AP1 transcription factor Fra2 is required for efficient cartilage development. Development (Cambridge, England). vol 131. issue 22. 2005-01-18. PMID:15509771. the absence of fra2 in embryos and newborns leads to reduced zones of hypertrophic chondrocytes and impaired matrix deposition in femoral and tibial growth plates, probably owing to impaired differentiation into hypertrophic chondrocytes. 2005-01-18 2023-08-12 mouse
Rama Garimella, Xiahong Bi, Nancy Camacho, Joseph B Sipe, H Clarke Anderso. Primary culture of rat growth plate chondrocytes: an in vitro model of growth plate histotype, matrix vesicle biogenesis and mineralization. Bone. vol 34. issue 6. 2005-01-14. PMID:15193542. chondrocytes of growth plate undergo proliferation, maturation, hypertrophy, matrix vesicle (mv) biogenesis and programmed cell death (pcd, apoptosis). 2005-01-14 2023-08-12 rat
I Villemure, M A Chung, C S Seck, M H Kimm, J R Matyas, N A Dunca. The effects of mechanical loading on the mRNA expression of growth-plate cells. Studies in health technology and informatics. vol 91. 2005-01-07. PMID:15457706. four key components were investigated: 18s (basic cell metabolism), type ii collagen (major extracellular matrix component), type x collagen (matrix component in hypertrophic zone) and pth-pthrp receptors (pre-hypertrophic chondrocytes). 2005-01-07 2023-08-12 rat
Dengshun Miao, Xiuying Bai, Dibyendu K Panda, Andrew C Karaplis, David Goltzman, Marc D McKe. Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice. Bone. vol 34. issue 4. 2004-12-22. PMID:15050894. in addition, growth plate osteocalcin and bone sialoprotein levels were decreased, while osteonectin was increased, in hypertrophic chondrocytes and cartilage matrix in hyp mice. 2004-12-22 2023-08-12 mouse
Dengshun Miao, Xiuying Bai, Dibyendu K Panda, Andrew C Karaplis, David Goltzman, Marc D McKe. Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice. Bone. vol 34. issue 4. 2004-12-22. PMID:15050894. these findings suggest that phex may control mineralization and removal of hypertrophic chondrocytes and cartilage matrix in growth plate by regulating the synthesis and deposition of certain bone matrix proteins and proteases such as mmp-9. 2004-12-22 2023-08-12 mouse
Darren J Kelly, Alison J Cox, Renae M Gow, Yuan Zhang, Bruce E Kemp, Richard E Gilber. Platelet-derived growth factor receptor transactivation mediates the trophic effects of angiotensin II in vivo. Hypertension (Dallas, Tex. : 1979). vol 44. issue 2. 2004-12-21. PMID:15197170. the findings of attenuation of vascular hypertrophy and matrix deposition by imatinib indicate that transactivation of the pdgfr in vivo contributes to the growth factor-like effects of ang ii, independent of its hemodynamic effects or its ability to induce tgf-beta gene expression. 2004-12-21 2023-08-12 rat