| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Long Chen, Charles R Yan. Interaction of dopamine D1 and NMDA receptors mediates acute clozapine potentiation of glutamate EPSPs in rat prefrontal cortex. Journal of neurophysiology. vol 87. issue 5. 2002-06-28. PMID:11976371. |
clozapine may modulate both glutamatergic and dopaminergic transmission in the prefrontal cortex (pfc) to achieve part of its therapeutic actions. |
2002-06-28 |
2023-08-12 |
rat |
| Long Chen, Charles R Yan. Interaction of dopamine D1 and NMDA receptors mediates acute clozapine potentiation of glutamate EPSPs in rat prefrontal cortex. Journal of neurophysiology. vol 87. issue 5. 2002-06-28. PMID:11976371. |
the dopamine released stimulates postsynaptic d1 receptor to modulate a lasting potentiation of the nmda receptor component of the glutamatergic synaptic responses in the pfc neuronal network. |
2002-06-28 |
2023-08-12 |
rat |
| Yukie Kawahara, Hiroshi Kawahara, Ben H C Westerin. Hypotension-induced dopamine release in prefrontal cortex is mediated by local glutamatergic projections at the level of nerve terminals. Journal of neurochemistry. vol 81. issue 2. 2002-06-26. PMID:12064475. |
hypotension-induced dopamine release in prefrontal cortex is mediated by local glutamatergic projections at the level of nerve terminals. |
2002-06-26 |
2023-08-12 |
Not clear |
| Bita Moghadda. Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders. Biological psychiatry. vol 51. issue 10. 2002-06-20. PMID:12007451. |
it is suggested that activation of glutamatergic neurotransmission in the pfc presents a common mechanism by which stress influences normal and abnormal processes that sustain affect and cognition. |
2002-06-20 |
2023-08-12 |
Not clear |
| Alberto Del Arco, Francisco Mor. NMDA and AMPA/kainate glutamatergic agonists increase the extracellular concentrations of GABA in the prefrontal cortex of the freely moving rat: modulation by endogenous dopamine. Brain research bulletin. vol 57. issue 5. 2002-05-23. PMID:11927365. |
nmda and ampa/kainate glutamatergic agonists increase the extracellular concentrations of gaba in the prefrontal cortex of the freely moving rat: modulation by endogenous dopamine. |
2002-05-23 |
2023-08-12 |
rat |
| Alberto Del Arco, Francisco Mor. NMDA and AMPA/kainate glutamatergic agonists increase the extracellular concentrations of GABA in the prefrontal cortex of the freely moving rat: modulation by endogenous dopamine. Brain research bulletin. vol 57. issue 5. 2002-05-23. PMID:11927365. |
using microdialysis in the prefrontal cortex, this study investigated first the effects of the ionotropic glutamatergic agonists nmda and ampa on extracellular concentrations of gaba, and second, the modulation of these effects by increasing endogenous dopamine. |
2002-05-23 |
2023-08-12 |
rat |
| Hiroko Togashi, Kazuo Nakamura, Machiko Matsumoto, Ken-ichi Ueno, Satoshi Ohashi, Hideya Saito, Mitsuhiro Yoshiok. Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats. Neuroscience letters. vol 320. issue 3. 2002-04-25. PMID:11852174. |
aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats. |
2002-04-25 |
2023-08-12 |
rat |
| Anne E Baldwin, Kenneth Sadeghian, Ann E Kelle. Appetitive instrumental learning requires coincident activation of NMDA and dopamine D1 receptors within the medial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826135. |
in the present studies we examined the role of dopaminergic d1 and glutamatergic nmda receptors within the prefrontal cortex of the rat during the development of adaptive instrumental learning. |
2002-02-27 |
2023-08-12 |
rat |
| Hong Wang, Virginia M Picke. Dopamine D2 receptors are present in prefrontal cortical afferents and their targets in patches of the rat caudate-putamen nucleus. The Journal of comparative neurology. vol 442. issue 4. 2002-02-21. PMID:11793342. |
glutamatergic neurons within the deep layers of the prefrontal cortex and dopaminergic neurons of the substantia nigra pars compacta preferentially terminate in patch-like regions within the caudate putamen nucleus (cpn). |
2002-02-21 |
2023-08-12 |
rat |
| J Amiel Rosenkranz, Anthony A Grac. Cellular mechanisms of infralimbic and prelimbic prefrontal cortical inhibition and dopaminergic modulation of basolateral amygdala neurons in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756516. |
however, it is unclear how two sets of glutamatergic inputs to the bla can impose opposing actions on bla-mediated behaviors; specifically, it is unclear how pfc inputs exert inhibitory actions over bla projection neurons. |
2002-02-04 |
2023-08-12 |
Not clear |
| J Amiel Rosenkranz, Anthony A Grac. Cellular mechanisms of infralimbic and prelimbic prefrontal cortical inhibition and dopaminergic modulation of basolateral amygdala neurons in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756516. |
in this study we use in vivo intracellular recordings to determine the means by which glutamatergic inputs from the pfc inhibit bla projection neurons, contrast that with glutamatergic inputs from the association sensory cortex (te3) that drive bla projection neurons, and examine the effects of da receptor activation on neuronal excitability, spontaneous postsynaptic potentials (psps), and pfc-evoked psps. |
2002-02-04 |
2023-08-12 |
Not clear |
| A Del Arco, F Mor. Dopamine release in the prefrontal cortex during stress is reduced by the local activation of glutamate receptors. Brain research bulletin. vol 56. issue 2. 2002-01-04. PMID:11704349. |
using microdialysis, we investigated the effects of the ionotropic glutamatergic agonists n-methyl-d-aspartate (nmda) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa) on the stress-induced dopamine release in the prefrontal cortex of the freely moving rat. |
2002-01-04 |
2023-08-12 |
rat |
| A Del Arco, F Mor. Dopamine release in the prefrontal cortex during stress is reduced by the local activation of glutamate receptors. Brain research bulletin. vol 56. issue 2. 2002-01-04. PMID:11704349. |
these same doses or lower doses of nmda (20 and 100 microm) and ampa (1 and 20 microm) did not significantly modify basal dopamine release in the prefrontal cortex, but higher doses of these glutamatergic agonists significantly decreased (nmda 500 microm) or increased (ampa 100 microm) basal dopamine release in this area of the brain. |
2002-01-04 |
2023-08-12 |
rat |
| A Del Arco, F Mor. Dopamine release in the prefrontal cortex during stress is reduced by the local activation of glutamate receptors. Brain research bulletin. vol 56. issue 2. 2002-01-04. PMID:11704349. |
these results show that the local activation of prefrontal glutamatergic ionotropic receptors reduces the stress-induced dopamine release in the prefrontal cortex of the rat. |
2002-01-04 |
2023-08-12 |
rat |
| T Suzuk. [Does 'selective binding profile' result in 'selective treatment'?]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 21. issue 1. 2001-07-19. PMID:11400320. |
moreover, martas increase intracellular concentrations of dopamine and norepinephrine in the prefrontal cortex and disinhibit the diminished glutamatergic transmission, which are expected to improve the negative symptoms, anxiety and depressive symptoms, and cognitive impairment that are difficult to be treated by other existing antipsychotics. |
2001-07-19 |
2023-08-12 |
Not clear |
| P J Baumbarger, M Muhlhauser, J Zhai, C R Yang, E S Nisenbau. Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408529. |
consistent with the in vitro data, ly404187 was 1000-fold more potent than cx516 in enhancing the probability of discharge of pfc neurons in response to stimulation of glutamatergic afferents from hippocampus in vivo. |
2001-07-19 |
2023-08-12 |
Not clear |
| L J Vanderschuren, P W Kaliva. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology. vol 151. issue 2-3. 2001-01-08. PMID:10972458. |
behavioral sensitization is the consequence of drug-induced neuroadaptive changes in a circuit involving dopaminergic and glutamatergic interconnections between the ventral tegmental area, nucleus accumbens, prefrontal cortex and amygdala. |
2001-01-08 |
2023-08-12 |
Not clear |
| L S Kegeles, A Abi-Dargham, Y Zea-Ponce, J Rodenhiser-Hill, J J Mann, R L Van Heertum, T B Cooper, A Carlsson, M Laruell. Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia. Biological psychiatry. vol 48. issue 7. 2000-12-05. PMID:11032974. |
the activity of midbrain dopaminergic neurons is regulated, in part, by glutamatergic projections from the pfc acting via glutamatergic n-methyl-d-aspartate (nmda) receptors. |
2000-12-05 |
2023-08-12 |
Not clear |
| R Takahata, B Moghadda. Target-specific glutamatergic regulation of dopamine neurons in the ventral tegmental area. Journal of neurochemistry. vol 75. issue 4. 2000-10-05. PMID:10987862. |
the present study provides evidence for this mechanism: in freely moving animals, blockade of basal glutamatergic activity in the vta by the selective alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa)/kainate antagonist ly293558 produced an increase in da release in the nac while significantly decreasing da release in the pfc. |
2000-10-05 |
2023-08-12 |
Not clear |
| N Auclair, S Otani, P Soubrie, F Crepe. Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons. Journal of neurophysiology. vol 83. issue 6. 2000-07-12. PMID:10848548. |
cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons. |
2000-07-12 |
2023-08-12 |
rat |