| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Auclair, S Otani, P Soubrie, F Crepe. Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons. Journal of neurophysiology. vol 83. issue 6. 2000-07-12. PMID:10848548. |
in this study, we tested first the acute effects of selective agonists and antagonist of cb-1 on glutamatergic excitatory postsynaptic currents (epscs) in slices of rat prefrontal cortex (pfc). |
2000-07-12 |
2023-08-12 |
rat |
| N Auclair, S Otani, P Soubrie, F Crepe. Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons. Journal of neurophysiology. vol 83. issue 6. 2000-07-12. PMID:10848548. |
these results demonstrate that cannabinoids influence glutamatergic synaptic transmission and plasticity in the pfc of rodent. |
2000-07-12 |
2023-08-12 |
rat |
| S Otani, N Auclair, J M Desce, M P Roisin, F Crépe. Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 22. 1999-12-02. PMID:10559388. |
tetanic stimuli to layer i-ii afferents in rat prefrontal cortex induced long-term depression (ltd) of layer i-ii to layer v pyramidal neuron glutamatergic synapses when tetani were coupled to bath application of dopamine. |
1999-12-02 |
2023-08-12 |
rat |
| A J Romanides, P Duffy, P W Kaliva. Glutamatergic and dopaminergic afferents to the prefrontal cortex regulate spatial working memory in rats. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392833. |
glutamatergic and dopaminergic afferents to the prefrontal cortex regulate spatial working memory in rats. |
1999-10-06 |
2023-08-12 |
rat |
| A J Romanides, P Duffy, P W Kaliva. Glutamatergic and dopaminergic afferents to the prefrontal cortex regulate spatial working memory in rats. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392833. |
the prefrontal cortex is innervated by dopaminergic afferents from the ventral tegmental area and glutamatergic afferents from the mediodorsal thalamus. |
1999-10-06 |
2023-08-12 |
rat |
| T C Napier, I Mitrovi. Opioid modulation of ventral pallidal inputs. Annals of the New York Academy of Sciences. vol 877. 1999-08-10. PMID:10415650. |
micror agonists decreased the variability and enhanced the acuity (e.g., "signal-to-noise" relationship) of vp responses to activation of glutamatergic inputs from the prefrontal cortex and amygdala. |
1999-08-10 |
2023-08-12 |
rat |
| P W Kalivas, M Nakamur. Neural systems for behavioral activation and reward. Current opinion in neurobiology. vol 9. issue 2. 1999-06-15. PMID:10322190. |
dopaminergic afferents serve to signal changes in rewarding stimuli, whereas glutamatergic input from the amygdala serves to cue behavior to conditioned reward, and afferents from the prefrontal cortex integrate information from short-term memory into behavioral responses. |
1999-06-15 |
2023-08-12 |
Not clear |
| G K Aghajanian, G J Mare. Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release. Brain research. vol 825. issue 1-2. 1999-05-26. PMID:10216183. |
previously, serotonin (5-ht) was found to induce a marked increase in glutamatergic spontaneous excitatory postsynaptic currents (epscs) in apical dendrites of layer v pyramidal cells of prefrontal cortex; this effect was mediated by 5-ht2a receptors, a proposed site of action of hallucinogenic and atypical antipsychotic drugs. |
1999-05-26 |
2023-08-12 |
rat |
| F Impagnatiello, A R Guidotti, C Pesold, Y Dwivedi, H Caruncho, M G Pisu, D P Uzunov, N R Smalheiser, J M Davis, G N Pandey, G D Pappas, P Tueting, R P Sharma, E Cost. A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 26. 1999-01-28. PMID:9861036. |
reln mrna was preferentially expressed in gabaergic interneurons of pfc, temporal cortex, hippocampus, and glutamatergic granule cells of cerebellum. |
1999-01-28 |
2023-08-12 |
mouse |
| T Ohnuma, S J Augood, H Arai, P J McKenna, P C Emso. Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain research. Molecular brain research. vol 56. issue 1-2. 1999-01-14. PMID:9602129. |
a disturbance of glutamatergic transmission has been suggested to contribute to the development of schizophrenic pathophysiology based primarily on the ability of glutamate receptor antagonists to induce schizophrenic-like symptoms, and recent studies suggesting reduced glutamatergic function in the prefrontal cortex (pfc) of individuals with a diagnosis of schizophrenia. |
1999-01-14 |
2023-08-12 |
human |
| J D Jentsch, A Tran, J R Taylor, R H Rot. Prefrontal cortical involvement in phencyclidine-induced activation of the mesolimbic dopamine system: behavioral and neurochemical evidence. Psychopharmacology. vol 138. issue 1. 1998-10-19. PMID:9694531. |
in summary, these studies show that phencyclidine activates the mesolimbic pathway through a mechanism in the prefrontal cortex, possibly by disinhibiting the cortical circuit and activating corticofugal glutamatergic release in the ventral tegmental area. |
1998-10-19 |
2023-08-12 |
rat |
| R Takahata, B Moghadda. Glutamatergic regulation of basal and stimulus-activated dopamine release in the prefrontal cortex. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751176. |
glutamatergic regulation of basal and stimulus-activated dopamine release in the prefrontal cortex. |
1998-10-14 |
2023-08-12 |
rat |
| R Takahata, B Moghadda. Glutamatergic regulation of basal and stimulus-activated dopamine release in the prefrontal cortex. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751176. |
the present study was undertaken to determine whether basal and stimulus-activated dopamine release in the prefrontal cortex (pfc) is regulated by glutamatergic afferents to the pfc or the ventral tegmental area (vta), the primary source of dopamine neurons that innervate the rodent pfc. |
1998-10-14 |
2023-08-12 |
rat |
| R Takahata, B Moghadda. Glutamatergic regulation of basal and stimulus-activated dopamine release in the prefrontal cortex. Journal of neurochemistry. vol 71. issue 4. 1998-10-14. PMID:9751176. |
in the context of brain disorders that may involve cortical dopamine dysfunction, the present findings suggest that abnormal basal or stimulus-activated dopamine neurotransmission in the pfc may be secondary to glutamatergic dysregulation. |
1998-10-14 |
2023-08-12 |
rat |
| S Otani, O Blond, J M Desce, F Crépe. Dopamine facilitates long-term depression of glutamatergic transmission in rat prefrontal cortex. Neuroscience. vol 85. issue 3. 1998-08-21. PMID:9639264. |
dopamine facilitates long-term depression of glutamatergic transmission in rat prefrontal cortex. |
1998-08-21 |
2023-08-12 |
rat |
| S Otani, O Blond, J M Desce, F Crépe. Dopamine facilitates long-term depression of glutamatergic transmission in rat prefrontal cortex. Neuroscience. vol 85. issue 3. 1998-08-21. PMID:9639264. |
using sharp-electrode intracellular recordings, we studied the dopaminergic facilitation of synaptic plasticity in layer i-ii afferents--layer v neuron glutamatergic synapses in rat prefrontal cortex in vitro. |
1998-08-21 |
2023-08-12 |
rat |
| R Karler, L D Calder, D K Thai, J B Bedingfiel. The role of dopamine and GABA in the frontal cortex of mice in modulating a motor-stimulant effect of amphetamine and cocaine. Pharmacology, biochemistry, and behavior. vol 60. issue 1. 1998-07-27. PMID:9610948. |
the results of previous studies have indicated that the activation of dopaminergic and gabaergic systems in the prefrontal cortex can decrease dopaminergic and glutamatergic activity in the striatum, ostensibly by the inhibition of corticofugal glutamatergic pathways. |
1998-07-27 |
2023-08-12 |
mouse |
| M Kuroda, J Yokofujita, K Murakam. An ultrastructural study of the neural circuit between the prefrontal cortex and the mediodorsal nucleus of the thalamus. Progress in neurobiology. vol 54. issue 4. 1998-05-08. PMID:9522395. |
thus, taken together with recent evidence that both the pfc-md and md-pfc pathways are glutamatergic and excitatory, the cortical excitation exerted by afferent fibers from md is transferred, not only back to md itself through deep pyramidal cells, but also the contralateral prefrontal cortex via pyramidal cells in layer iii of the ipsilateral prefrontal cortex. |
1998-05-08 |
2023-08-12 |
rat |
| P S Goldman-Rakic, L D Selemo. Functional and anatomical aspects of prefrontal pathology in schizophrenia. Schizophrenia bulletin. vol 23. issue 3. 1997-11-25. PMID:9327508. |
we outline several direct and indirect intercellular mechanisms for modulating working memory function in the prefrontal cortex based on the localization of dopamine receptors on the distal dendrites and spines of glutamatergic pyramidal cells and on gamma-aminobutyric acid (gaba) ergic interneurons in the prefrontal cortex. |
1997-11-25 |
2023-08-12 |
Not clear |
| M Bubser, M G Feenstra, E B Erdtsieck-Ernste, M H Botterblom, H F Van Uum, C W Poo. Modulatory role of catecholamines in the transsynaptic expression of c-fos in the rat medial prefrontal cortex induced by disinhibition of the mediodorsal thalamus: a study employing microdialysis and immunohistochemistry. Brain research. vol 749. issue 2. 1997-05-06. PMID:9138721. |
it is suggested that the thalamically induced c-fos response is directly mediated by excitatory, presumably glutamatergic, transmission and not indirectly by an activation of catecholaminergic afferents of the pfc. |
1997-05-06 |
2023-08-12 |
rat |