| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anastasia P Athanasoulia-Kaspar, Kathrin H Popp, Gunter Karl Stall. Neuropsychiatric and metabolic aspects of dopaminergic therapy: perspectives from an endocrinologist and a psychiatrist. Endocrine connections. vol 7. issue 2. 2020-09-30. PMID:29378769. |
the dopaminergic treatment includes ergot and non-ergot derivatives with high affinity for the dopamine receptors d1 or/and d2. |
2020-09-30 |
2023-08-13 |
Not clear |
| Anastasia P Athanasoulia-Kaspar, Kathrin H Popp, Gunter Karl Stall. Neuropsychiatric and metabolic aspects of dopaminergic therapy: perspectives from an endocrinologist and a psychiatrist. Endocrine connections. vol 7. issue 2. 2020-09-30. PMID:29378769. |
through the activation of the dopaminergic pathway on pituitary lactotrophs, the dopamine agonists inhibit the prolactin synthesis and secretion, therefore normalizing the prolactin levels and restoring eugonadism, but they also lead to tumour shrinkage. |
2020-09-30 |
2023-08-13 |
Not clear |
| Anastasia P Athanasoulia-Kaspar, Kathrin H Popp, Gunter Karl Stall. Neuropsychiatric and metabolic aspects of dopaminergic therapy: perspectives from an endocrinologist and a psychiatrist. Endocrine connections. vol 7. issue 2. 2020-09-30. PMID:29378769. |
they usually have de novo onset after initiation of the dopaminergic treatment and have been mainly reported in patients with parkinson's disease, who are being treated with higher doses of dopamine agonists. |
2020-09-30 |
2023-08-13 |
Not clear |
| Michael R Post, Ori J Lieberman, Eugene V Mosharo. Can Interactions Between α-Synuclein, Dopamine and Calcium Explain Selective Neurodegeneration in Parkinson's Disease? Frontiers in neuroscience. vol 12. 2020-09-30. PMID:29593491. |
susceptible neuronal populations in pd, dopaminergic neurons of the substantia nigra pars compacta (snpc) and the locus coeruleus (lc), are distinguished by relatively high cytoplasmic concentrations of dopamine and calcium ions. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xian-Si Zeng, Wen-Shuo Geng, Jin-Jing Jia, Lei Chen, Peng-Peng Zhan. Cellular and Molecular Basis of Neurodegeneration in Parkinson Disease. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:29719505. |
in this review, we summarize the mutations of main seven genes (α-synuclein, lrrk2, pink1, parkin, dj-1, vps35 and gba1) linked to pd, discuss the potential mechanisms for the loss of dopaminergic neurons (dopamine metabolism, mitochondrial dysfunction, endoplasmic reticulum stress, impaired autophagy, and deregulation of immunity) in pd, and expect the development direction for treatment of pd. |
2020-09-30 |
2023-08-13 |
Not clear |
| Manuel Menéndez-González, Tania Álvarez-Avellón, José M Salas-Pacheco, Benito de Celis-Alonso, Kathryn A Wyman-Chick, Oscar Arias-Carrió. Frontotemporal Lobe Degeneration as Origin of Scans Without Evidence of Dopaminergic Deficit. Frontiers in neurology. vol 9. 2020-09-30. PMID:29881367. |
the term scans without evidence of dopaminergic deficit (swedd) can be associated with any patient diagnosed at first with parkinson's disease but with a negative dopamine transporter-single photon emission computed tomography (datspect), which does not confirm the presynaptic dopaminergic deficiency. |
2020-09-30 |
2023-08-13 |
Not clear |
| Harumasa Takan. Cognitive Function and Monoamine Neurotransmission in Schizophrenia: Evidence From Positron Emission Tomography Studies. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:29896132. |
with regard to the dopaminergic system, some studies have examined the association of dopamine d1 and d2/d3 receptors, dopamine transporters, and dopamine synthesis capacity with various cognitive functions in schizophrenia. |
2020-09-30 |
2023-08-13 |
human |
| Akanksha Mishra, Sonu Singh, Shubha Shukl. Physiological and Functional Basis of Dopamine Receptors and Their Role in Neurogenesis: Possible Implication for Parkinson's disease. Journal of experimental neuroscience. vol 12. 2020-09-30. PMID:29899667. |
reduction in dopamine content in the nigrostriatal pathway is associated with the development of pd, along with the degeneration of dopaminergic neurons in the substantia nigra region. |
2020-09-30 |
2023-08-13 |
Not clear |
| Bridget Martinez, Philip V Peplo. Neuroprotection by immunomodulatory agents in animal models of Parkinson's disease. Neural regeneration research. vol 13. issue 9. 2020-09-30. PMID:30127102. |
all of the agents were effective in reducing the motor deficit and alleviating dopaminergic neurotoxicity and, when measured, preventing the decrease of dopamine upon being administered therapeutically after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 6-hydroxydopamine, rotenone-lesioning or delivery of adeno-associated virus-α-synuclein to the ventral midbrain of animals. |
2020-09-30 |
2023-08-13 |
Not clear |
| Cory Richman, Sabih Rashid, Shreya Prashar, Ram Mishra, P Ravi Selvaganapathy, Bhagwati P Gupt. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30147641. |
mesencephalic astrocyte-derived neurotrophic factor (manf) and cerebral dopamine neurotrophic factor (cdnf) are two recently identified members of a novel family of ntfs in vertebrates that function to protect dopaminergic neurons. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yuko Nakamura, Naohiro Okada, Akira Kunimatsu, Kiyoto Kasai, Shinsuke Koik. Anatomical Templates of the Midbrain Ventral Tegmental Area and Substantia Nigra for Asian Populations. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30210369. |
considering that the ventral tegmental area (vta) and substantia nigra (sn) in the midbrain are the primary dopamine producers, creating reliable anatomical templates of the vta and sn through neuroimaging studies would be useful for achieving a detailed understanding of this dopaminergic system. |
2020-09-30 |
2023-08-13 |
Not clear |
| Fatemeh N Emamzadeh, Andrei Surgucho. Parkinson's Disease: Biomarkers, Treatment, and Risk Factors. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30214392. |
dopamine is a neurotransmitter involved in movement, motivation, memory, and other functions; its level is decreased in pd brain as a result of dopaminergic cell death. |
2020-09-30 |
2023-08-13 |
Not clear |
| Haitao Wang, Jiangping Xu, Philip Lazarovici, Remi Quirion, Wenhua Zhen. cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30214393. |
the dopamine hypothesis states that, in schizophrenia, dopaminergic signal transduction is hyperactive. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yu Zhou, Yukio Yamamura, Masatoshi Ogawa, Ryosuke Tsuji, Koichiro Tsuchiya, Jiro Kasahara, Satoshi Got. c-Abl Inhibition Exerts Symptomatic Antiparkinsonian Effects Through a Striatal Postsynaptic Mechanism. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:30505273. |
parkinson's disease (pd) is caused by a progressive degeneration of nigral dopaminergic cells leading to striatal dopamine deficiency. |
2020-09-30 |
2023-08-13 |
mouse |
| Mei-Fang Liu, Yan Xue, Cui Liu, Yun-Hai Liu, Hui-Ling Diao, Ying Wang, Yi-Peng Pan, Lei Che. Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson's Disease. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:30524223. |
the results from animal experiments demonstrated that orexin-a attenuated the loss of dopaminergic neurons and the decrease of tyrosine hydroxylase (th) expression in the substantia nigra, normalized the striatal dopaminergic fibers, and prevented the depletion of dopamine and its metabolites in the striatum. |
2020-09-30 |
2023-08-13 |
mouse |
| Rafaela Carneiro Cordeiro, Adriano José Maia Chaves Filho, Nayana Soares Gomes, Viviane de Sousa Tomaz, Camila Dantas Medeiros, Ana Isabelle de Góis Queiroz, Michael Maes, Danielle S Macedo, Andre F Carvalh. Leptin Prevents Lipopolysaccharide-Induced Depressive-Like Behaviors in Mice: Involvement of Dopamine Receptors. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:30949073. |
to evaluate the involvement of dopamine receptors, different experimental groups were pretreated with either the dopaminergic antagonist sch23390, for d1 receptors or raclopride, for d2/d3 receptors, prior to leptin injection. |
2020-09-30 |
2023-08-13 |
mouse |
| Lisa M Smits, Lydia Reinhardt, Peter Reinhardt, Michael Glatza, Anna S Monzel, Nancy Stanslowsky, Marcelo D Rosato-Siri, Alessandra Zanon, Paul M Antony, Jessica Bellmann, Sarah M Nicklas, Kathrin Hemmer, Xiaobing Qing, Emanuel Berger, Norman Kalmbach, Marc Ehrlich, Silvia Bolognin, Andrew A Hicks, Florian Wegner, Jared L Sterneckert, Jens C Schwambor. Modeling Parkinson's disease in midbrain-like organoids. NPJ Parkinson's disease. vol 5. 2020-09-30. PMID:30963107. |
these organoids are composed of midbrain dopaminergic neurons (mdans), which produce and secrete dopamine. |
2020-09-30 |
2023-08-13 |
human |
| Victoria B Velásquez, Gabriel A Zamorano, Jonathan Martínez-Pinto, Christian Bonansco, Pablo Jara, Gonzalo E Torres, Georgina M Renard, Ramón Sotomayor-Zárat. Programming of Dopaminergic Neurons by Early Exposure to Sex Hormones: Effects on Morphine-Induced Accumbens Dopamine Release, Reward, and Locomotor Behavior in Male and Female Rats. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:30971928. |
programming of dopaminergic neurons by early exposure to sex hormones: effects on morphine-induced accumbens dopamine release, reward, and locomotor behavior in male and female rats. |
2020-09-30 |
2023-08-13 |
rat |
| Aimée I Vester, Merry Chen, Carmen J Marsit, W Michael Caudl. A Neurodevelopmental Model of Combined Pyrethroid and Chronic Stress Exposure. Toxics. vol 7. issue 2. 2020-09-30. PMID:31052489. |
midbrain rna expression as well as striatal and cortical protein expression of key dopaminergic components were investigated, in addition to adhd-like behavioral tasks and electrochemical dopamine dynamics via fast-scan cyclic voltammetry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Valentina Bassareo, Giuseppe Talani, Roberto Frau, Simona Porru, Michela Rosas, Sanjay B Kasture, Alessandra T Peana, Eleonora Loi, Enrico Sanna, Elio Acqua. Inhibition of Morphine- and Ethanol-Mediated Stimulation of Mesolimbic Dopamine Neurons by Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31275092. |
inhibition of morphine- and ethanol-mediated stimulation of mesolimbic dopamine neurons by morphine- and ethanol-induced stimulation of neuronal firing of ventral tegmental area (vta) dopaminergic neurons and of dopamine (da) transmission in the shell of the nucleus accumbens (acbsh) represents a crucial electrophysiological and neurochemical response underlying the ability of these compounds to elicit motivated behaviors and trigger a cascade of plasticity-related biochemical events. |
2020-09-30 |
2023-08-13 |
Not clear |