| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Satoshi Nakajima, Yasutaka Fushimi, Hirotsugu Kawashima, Toshiya Murai, Yuji Nakamot. Cerebral Infarction With Increased Uptake on 123I-FP-CIT SPECT. Clinical nuclear medicine. vol 46. issue 4. 2021-04-01. PMID:33181738. |
123i-fp-cit has high binding affinity for dopamine transporters, especially in the nerve endings of nigrostriatal dopaminergic neurons. |
2021-04-01 |
2023-08-13 |
Not clear |
| Daniel Je Green, Andrew C Li. How nitric oxide helps update memories. eLife. vol 9. 2021-03-30. PMID:31913122. |
some dopaminergic neurons release both dopamine and nitric oxide to increase the flexibility of olfactory memories. |
2021-03-30 |
2023-08-13 |
Not clear |
| Xue Gong, Xiao-Hua Wu, Ai-Lin Liu, Kang-Wei Qian, Yun-Yun Li, Yuan-Yuan Ma, Furong Huang, Qiongsi Wang, Hao Wu, Xiangtian Zhou, Jia Qu, Fei Yuan, Yong-Mei Zhong, Xiong-Li Yang, Shi-Jun Wen. Optic nerve crush modulates refractive development of the C57BL/6 mouse by changing multiple ocular dimensions. Brain research. vol 1726. 2021-03-29. PMID:31672473. |
onc did not change the density of dopaminergic amacrine cells, but increased retinal levels of dopamine and dopac. |
2021-03-29 |
2023-08-13 |
mouse |
| Jelena Osmanovic Barilar, Ana Knezovic, Ana Babic Perhoc, Jan Homolak, Peter Riederer, Melita Salkovic-Petrisi. Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 127. issue 2. 2021-03-26. PMID:32030485. |
mitochondrial damage and co-expression of insulin receptors, glucose transporter-2 and dopamine transporter on the membrane of particular neurons as well as astrocytes seem to be the key points which are further discussed in a context of alterations in insulin signalling in the brain and its interaction with dopaminergic transmission, particularly regarding the time frame of the experimental ad/pd pathology appearance and the correlation with cognitive and motor symptoms. |
2021-03-26 |
2023-08-13 |
Not clear |
| Adrienne Mueller, Rebecca M Krock, Steven Shepard, Tirin Moor. Dopamine Receptor Expression Among Local and Visual Cortex-Projecting Frontal Eye Field Neurons. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 1. 2021-03-22. PMID:31038690. |
our results demonstrate that dopamine tends to act directly on the output of the fef and that dopaminergic modulation of top-down projections to visual cortex is achieved predominately via d1rs. |
2021-03-22 |
2023-08-13 |
Not clear |
| Arvie Camille V de Guzman, Md Abdur Razzak, Batmagnai Purevdulam, Shin Sik Cho. Anti-Parkinson's Disease Function of Dioscin-Zein-Carboxymethyl Cellulose Nanocomplex in Caenorhabditis elegans. Biotechnology journal. vol 15. issue 12. 2021-03-22. PMID:32725951. |
parkinson's disease (pd) is characterized by the loss of dopamine (da) and dopaminergic neurons. |
2021-03-22 |
2023-08-13 |
caenorhabditis_elegans |
| Mohan K Ghanta, P Elango, Bhaskar L V K . Current Therapeutic Strategies and Perspectives for Neuroprotection in Parkinson's Disease. Current pharmaceutical design. vol 26. issue 37. 2021-03-19. PMID:32065086. |
treatment of parkinson's disease (pd) through dopamine replacement strategies may provide improvement in early stages and this treatment response is related to dopaminergic neuronal mass which decreases in advanced stages. |
2021-03-19 |
2023-08-13 |
Not clear |
| Taylor A Gee, Nathan C Weintraub, Dong Lu, Caroline E Phelps, Edita Navratilova, Michael L Heien, Frank Porrec. A pain-induced tonic hypodopaminergic state augments phasic dopamine release in the nucleus accumbens. Pain. vol 161. issue 10. 2021-03-19. PMID:32453137. |
capsaicin treatment in the alternate cornea, however, again produced coincident decreased dopaminergic tone and increased phasic dopamine release. |
2021-03-19 |
2023-08-13 |
rat |
| Taylor A Gee, Nathan C Weintraub, Dong Lu, Caroline E Phelps, Edita Navratilova, Michael L Heien, Frank Porrec. A pain-induced tonic hypodopaminergic state augments phasic dopamine release in the nucleus accumbens. Pain. vol 161. issue 10. 2021-03-19. PMID:32453137. |
our data show that (1) the mesolimbic dopamine circuit reliably encodes acute noxious stimuli; (2) ongoing pain produces decreases in dopaminergic tone; and (3) pain-induced decreases in tonic dopamine correspond to augmented evoked phasic dopamine release. |
2021-03-19 |
2023-08-13 |
rat |
| Taylor A Gee, Nathan C Weintraub, Dong Lu, Caroline E Phelps, Edita Navratilova, Michael L Heien, Frank Porrec. A pain-induced tonic hypodopaminergic state augments phasic dopamine release in the nucleus accumbens. Pain. vol 161. issue 10. 2021-03-19. PMID:32453137. |
enhanced phasic dopamine neurotransmission resulting from salient stimuli may contribute to increased impulsivity and cognitive deficits often observed in conditions associated with decreased dopaminergic tone, including parkinson disease and chronic pain. |
2021-03-19 |
2023-08-13 |
rat |
| M V Melnikov, M V Pashenkov, A N Boyk. [The prospect of dopaminergic therapy in multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 121. issue 2. 2021-03-18. PMID:33728853. |
dopamine can modulate th17 cells function as well as dendritic cell-mediated th17-immune response that allows considering dopaminergic receptors as a new therapeutic target in multiple sclerosis. |
2021-03-18 |
2023-08-13 |
Not clear |
| Danielle Wasserman, Dorothea Bindman, Alexander D Nesbitt, Diana Cash, Milan Milosevic, Paul T Francis, K Ray Chaudhuri, Guy D Leschziner, Luigi Ferini-Strambi, Clive Ballard, Amy Eccles, Ivana Rosenzwei. Striatal Dopaminergic Deficit and Sleep in Idiopathic Rapid Eye Movement Behaviour Disorder: An Explorative Study. Nature and science of sleep. vol 13. 2021-03-17. PMID:33447113. |
neuroimaging studies of striatal dopamine transporter uptake tracer signaling suggest increasing dopaminergic deficit across the continuum of the alpha-synucleinopathies, with early sleep dysfunction suggestive of early caudate dysfunction. |
2021-03-17 |
2023-08-13 |
Not clear |
| Michael R Kilbour. Biomedicines. vol 9. issue 2. 2021-03-16. PMID:33499179. |
in vivo pet imaging of dopaminergic functions of the central nervous system (cns) including dopamine synthesis, vesicular storage, synaptic release and receptor binding, and reuptake processes, are now routinely used for studies in neurology, psychiatry, drug abuse and addiction, and drug development. |
2021-03-16 |
2023-08-13 |
Not clear |
| Nadja Mannal, Katharina Kleiner, Michael Fauler, Antonios Dougalis, Christina Poetschke, Birgit Lis. Multi-Electrode Array Analysis Identifies Complex Dopamine Responses and Glucose Sensing Properties of Substantia Nigra Neurons in Mouse Brain Slices. Frontiers in synaptic neuroscience. vol 13. 2021-03-16. PMID:33716704. |
dopaminergic (da) midbrain neurons within the substantia nigra (sn) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. |
2021-03-16 |
2023-08-13 |
mouse |
| P Stepanova, V Srinivasan, D Lindholm, M H Voutilaine. Cerebral dopamine neurotrophic factor (CDNF) protects against quinolinic acid-induced toxicity in in vitro and in vivo models of Huntington's disease. Scientific reports. vol 10. issue 1. 2021-03-15. PMID:33154393. |
cerebral dopamine neurotrophic factor (cdnf) is an endoplasmic reticulum (er) located protein with neurotrophic factor (ntf) properties, protecting and restoring the function of dopaminergic neurons in animal models of pd more effectively than other ntfs. |
2021-03-15 |
2023-08-13 |
rat |
| Yasuhisa Ano, Shiho Kitaoka, Rena Ohya, Keiji Kondo, Tomoyuki Furuyashik. Hop Bitter Acids Increase Hippocampal Dopaminergic Activity in a Mouse Model of Social Defeat Stress. International journal of molecular sciences. vol 21. issue 24. 2021-03-15. PMID:33348553. |
since acute oral consumption with iaa increases dopamine levels in hippocampus and improves memory impairment via vagal nerve activation, here we investigated the effects of chronic administration of hop bitter acids on the dopaminergic activity associated with emotional disturbance in a mouse model of repeated social defeat stress (r-sds). |
2021-03-15 |
2023-08-13 |
mouse |
| Yasuhisa Ano, Shiho Kitaoka, Rena Ohya, Keiji Kondo, Tomoyuki Furuyashik. Hop Bitter Acids Increase Hippocampal Dopaminergic Activity in a Mouse Model of Social Defeat Stress. International journal of molecular sciences. vol 21. issue 24. 2021-03-15. PMID:33348553. |
chronic administration of iaa and mhba significantly increased dopaminergic activity based on the dopamine metabolite to dopamine ratio in the hippocampus and medial prefrontal cortex following r-sds. |
2021-03-15 |
2023-08-13 |
mouse |
| Tamriage A Martin, Hilary R Smith, Deborah J Luessen, Rong Chen, Linda J Porrin. Functional brain activity is globally elevated by dopamine D2 receptor knockdown in the ventral tegmental area. Brain research. vol 1727. 2021-03-10. PMID:31726041. |
regulation of dopamine transmission within this system is achieved in part through a negative feedback mechanism via dopamine d2 autoreceptors located on somatodendrites and terminals of vta dopaminergic neurons. |
2021-03-10 |
2023-08-13 |
rat |
| Jose L Labandeira-Garcia, Rita Valenzuela, Maria A Costa-Besada, Begoña Villar-Cheda, Ana I Rodriguez-Pere. The intracellular renin-angiotensin system: Friend or foe. Some light from the dopaminergic neurons. Progress in neurobiology. vol 199. 2021-03-10. PMID:33039415. |
the dopaminergic system is particularly interesting to investigate the ras as important functional interactions between dopamine and ras have been observed in the brain and several peripheral tissues. |
2021-03-10 |
2023-08-13 |
Not clear |
| Ji Ae Lee, Hye Ri Kim, Hyo Jin Son, Nari Shin, Se Hee Han, Chan Seong Cheong, Dong Jin Kim, Onyou Hwan. A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons. Experimental neurology. vol 332. 2021-03-09. PMID:32580013. |
in mptp-treated mice that received kkc080106 orally, the compound blocked microglial activation, protected the nigral dopaminergic neurons from degeneration, and prevented development of the dopamine deficiency-related motor deficits. |
2021-03-09 |
2023-08-13 |
mouse |