Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Giulia Gaggi, Andrea Di Credico, Pascal Izzicupo, Giovanni Iannetti, Angela Di Baldassarre, Barbara Ghinass. Chemical and Biological Molecules Involved in Differentiation, Maturation, and Survival of Dopaminergic Neurons in Health and Parkinson's Disease: Physiological Aspects and Clinical Implications. Biomedicines. vol 9. issue 7. 2021-07-27. PMID:34209807. |
parkinson's disease (pd) is one of the most common neurodegenerative disease characterized by a specific and progressive loss of dopaminergic (da) neurons and dopamine, causing motor dysfunctions and impaired movements. |
2021-07-27 |
2023-08-13 |
human |
Abhinaba Ghosh, Faghihe Massaeli, Kyron D Power, Tamunotonye Omoluabi, Sarah E Torraville, Julia B Pritchett, Tayebeh Sepahvand, Vanessa D Strong, Camila Reinhardt, Xihua Chen, Gerard M Martin, Carolyn W Harley, Qi Yua. Locus Coeruleus Activation Patterns Differentially Modulate Odor Discrimination Learning and Odor Valence in Rats. Cerebral cortex communications. vol 2. issue 2. 2021-07-24. PMID:34296171. |
however, 10-hz phasic light-mediated learning facilitation was prevented by a dopaminergic antagonist in the pc, or by ventral tegmental area (vta) silencing with lidocaine, suggesting a lc-vta-pc dopamine circuitry involvement. |
2021-07-24 |
2023-08-13 |
rat |
Yong Wang, Lu Yao, Shasha Gao, Gejuan Zhang, Qiongchi Zhang, Wanyuan Liu, Yingqiong Zhou, Yina Sun, Jie Feng, Jian Li. Inhibition of striatal dopamine D Brain research. vol 1754. 2021-07-22. PMID:33422541. |
striatal dopaminergic signaling plays a critical role in the pathogenesis of lid through its interactions with dopamine receptors. |
2021-07-22 |
2023-08-13 |
Not clear |
Mutsuo Nuriya, Yosuke Ashikari, Takanori Iino, Takuya Asai, Jingwen Shou, Keiko Karasawa, Kaho Nakamura, Yasuyuki Ozeki, Yukari Fujimoto, Masato Yasu. Alkyne-Tagged Dopamines as Versatile Analogue Probes for Dopaminergic System Analysis. Analytical chemistry. vol 93. issue 27. 2021-07-21. PMID:34210142. |
however, the lack of probes that mimic dopamine in living tissues, owing to the neurotransmitter's small size, has hampered analysis of the dopaminergic system. |
2021-07-21 |
2023-08-13 |
Not clear |
Debapriya Garabadu, Nidhi Agrawa. Naringin Exhibits Neuroprotection Against Rotenone-Induced Neurotoxicity in Experimental Rodents. Neuromolecular medicine. vol 22. issue 2. 2021-07-19. PMID:31916219. |
parkinson's disease (pd) is a neurodegenerative disease that is accompanied with the loss of dopaminergic neurons in the substantia nigra pars compacta which subsequently leads to a reduction in the dopamine level in the striatum. |
2021-07-19 |
2023-08-13 |
rat |
Luke J Ney, Jane Akhurst, Raimondo Bruno, Patrick A F Laing, Allison Matthews, Kim L Felmingha. Dopamine, endocannabinoids and their interaction in fear extinction and negative affect in PTSD. Progress in neuro-psychopharmacology & biological psychiatry. vol 105. 2021-07-19. PMID:32991952. |
here we review the dopamine literature and incorporate it with a growing field of research that describes both the contribution of endocannabinoids to fear extinction and ptsd, as well as the interactions between dopaminergic and endocannabinoid systems underlying this disorder. |
2021-07-19 |
2023-08-13 |
Not clear |
Yanyun Sun, Xiao-Jun Lu, Xinghui Fu, Ye Zhang, Yan Zhan, Jiabing Liu, Lingxia Zhao, Chun-Lin Xi. Engrafted primary type-2 astrocytes improve the recovery of the nigrostriatal pathway in a rat model of Parkinson's disease. Molecular and cellular biochemistry. vol 476. issue 2. 2021-07-19. PMID:33070275. |
parkinson's disease (pd) is a disorder characterized by a progressive loss of the dopaminergic neurons in the substantia nigra and a depletion of the neurotransmitter dopamine in the striatum. |
2021-07-19 |
2023-08-13 |
rat |
Diego Luis-Ravelo, Felipe Fumagallo-Reading, Javier Castro-Hernandez, Pedro Barroso-Chinea, Domingo Afonso-Oramas, Alejandro Febles-Casquero, Ignacio Cruz-Muros, Josmar Salas-Hernandez, Virginia Mesa-Infante, Julia Rodriguez-Nuñez, Tomas Gonzalez-Hernande. Prolonged dopamine D Pharmacological research. vol 165. 2021-07-16. PMID:33484816. |
prolonged dopamine d the dopamine transporter (dat) is a membrane glycoprotein in dopaminergic neurons, which modulates extracellular and intracellular dopamine levels. |
2021-07-16 |
2023-08-13 |
Not clear |
Sharonda Harris, Renee Afram, Takashi Shimano, Bozena Fyk-Kolodziej, Paul D Walker, Rod D Braun, Avril Genene Hol. Dopamine in Auditory Nuclei and Lemniscal Projections is Poised to Influence Acoustic Integration in the Inferior Colliculus. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:33746717. |
these results suggest that several auditory nuclei that project to the inferior colliculus contain dopamine, dopaminergic neurons in the lateral lemniscus project to the inferior colliculus and that dopaminergic neurotransmission is poised to play a pivotal role in the function of the inferior colliculus. |
2021-07-16 |
2023-08-13 |
rat |
Yosef Ron, Hedva Lerman, Einat Even-Sapi. [METABOLIC AND DOPAMINERGIC BRAIN FUNCTIONAL IMAGING IN DEMENTIA WITH LEWY BODIES]. Harefuah. vol 160. issue 7. 2021-07-16. PMID:34263568. |
cortical metabolism was obtained by pet with labeled glucose (fdg) and the dopaminergic activity by labeled precursor (f-dopa) of the neurotransmitter dopamine. |
2021-07-16 |
2023-08-13 |
Not clear |
Nageen Mubashir, Rida Fatima, Sadaf Naee. Identification of Novel Phyto-chemicals from Ocimum basilicum for the Treatment of Parkinson's Disease using In Silico Approach. Current computer-aided drug design. vol 16. issue 4. 2021-07-15. PMID:32883197. |
parkinson's disease is characterized by decreased level of dopaminergic neurotransmitters and this decrease is due to the degradation of dopamine by protein monoamine oxidase b (mao-b). |
2021-07-15 |
2023-08-13 |
Not clear |
Sergi Ferré, Xavier Guitart, César Quiroz, William Rea, Celia García-Malo, Diego Garcia-Borreguero, Richard P Allen, Christopher J Earle. Akathisia and Restless Legs Syndrome: Solving the Dopaminergic Paradox. Sleep medicine clinics. vol 16. issue 2. 2021-07-13. PMID:33985651. |
this article proposes that it involves an increased presynaptic dopaminergic transmission in the ventral striatum and concomitant strong activation of postsynaptic dopamine d |
2021-07-13 |
2023-08-13 |
Not clear |
Antonio Verduzco-Mendoza, Paul Carrillo-Mora, Alberto Avila-Luna, Arturo Gálvez-Rosas, Adriana Olmos-Hernández, Daniel Mota-Rojas, Antonio Bueno-Nav. Role of the Dopaminergic System in the Striatum and Its Association With Functional Recovery or Rehabilitation After Brain Injury. Frontiers in neuroscience. vol 15. 2021-07-13. PMID:34248494. |
previous studies have shown that dopamine (da) neurotransmission is disrupted following moderate to severe tbi and have reported beneficial effects of drugs that affect the dopaminergic system. |
2021-07-13 |
2023-08-13 |
Not clear |
Yuan-Bing Huang, Ze-Gang Ma, Chao Zheng, Xiao-Kuang K Ma, Devin H Taylor, Ming Gao, Ronald J Lukas, Jie W. Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells. Acta pharmacologica Sinica. 2021-07-13. PMID:34253876. |
l-tetrahydropalmatine (l-thp) is an active ingredient of the chinese medicinal herb corydalis ambigua that possesses rich neuropharmacological actions on dopamine (da) receptors in the mesocorticolimbic dopaminergic reward pathway. |
2021-07-13 |
2023-08-13 |
human |
Bruk Getachew, Antonei B Csoka, Amna Bhatti, Robert L Copeland, Yousef Tizab. Butyrate Protects Against Salsolinol-Induced Toxicity in SH-SY5Y Cells: Implication for Parkinson's Disease. Neurotoxicity research. vol 38. issue 3. 2021-07-09. PMID:32572814. |
sals, an endogenous product of aldehyde and dopamine condensation, may be selectively toxic to dopaminergic neurons. |
2021-07-09 |
2023-08-13 |
human |
Giacomo Grassi, Giovanni Albani, Federica Terenzi, Lorenzo Razzolini, Silvia Rama. New pharmacological and neuromodulation approaches for impulsive-compulsive behaviors in Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 7. 2021-07-09. PMID:33852081. |
these behaviors have been consistently linked to the use of dopaminergic medications used to treat pd motor symptoms (dopamine agonists, levodopa, and other agents) and less consistently to neuromodulation techniques such as deep brain stimulation (dbs). |
2021-07-09 |
2023-08-13 |
Not clear |
Atsushi Takeda, Masahiko Tomiyama, Ritsuko Hanajim. [The Relationship Between Pathophysiology and Neurotransmitters in Parkinson's Disease]. Brain and nerve = Shinkei kenkyu no shinpo. vol 73. issue 7. 2021-07-09. PMID:34234041. |
the major motor symptoms of pd are mainly caused by dopamine (da) deficiency due to the loss of dopaminergic neurons in the substantia nigra. |
2021-07-09 |
2023-08-13 |
Not clear |
Yiqiu Liu, Junyu Deng, Ye Liu, Wei Li, Xuqiang Ni. FGF, Mechanism of Action, Role in Parkinson's Disease, and Therapeutics. Frontiers in pharmacology. vol 12. 2021-07-09. PMID:34234672. |
the death or dysfunction of dopaminergic neurons in the dense part of the substantia nigra leads to dopamine deficiency in the basal ganglia and motor dysfunction. |
2021-07-09 |
2023-08-13 |
Not clear |
Owen Y Chao, Salil S Pathak, Hao Zhang, Nathan Dunaway, Jay-Shake Li, Claudia Mattern, Susanne Nikolaus, Joseph P Huston, Yi-Mei Yan. Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism. Molecular brain. vol 13. issue 1. 2021-07-08. PMID:32778145. |
altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism. |
2021-07-08 |
2023-08-13 |
mouse |
Zulfiye Gul, Gozde Duyu, Burcin Altinbas, R Levent Buyukuysa. K channel blockage with 3,4-diaminopyridine potentiates the effect of L-DOPA on dopamine release in striatal slices prepared from 6-OHDA pre-treated rats. Experimental brain research. vol 238. issue 11. 2021-07-07. PMID:32870323. |
it has been shown that 3,4-diaminopyridine (3,4-dap), a k channel blocker, increased dopamine release from striatal slices by increasing neuronal firing in striatal dopaminergic terminals. |
2021-07-07 |
2023-08-13 |
rat |