| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ichiro Kawahata, Tomoki Sekimori, Haoyang Wang, Yanyan Wang, Toshikuni Sasaoka, Luc Bousset, Ronald Melki, Tomohiro Mizobata, Yasushi Kawata, Kohji Fukunag. Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons. Biomedicines. vol 9. issue 1. 2021-02-18. PMID:33429895. |
fabp3 is abundant in dopaminergic neurons and interacts with dopamine d2 receptors, specifically the long type (d |
2021-02-18 |
2023-08-13 |
Not clear |
| Mehmet Senel, Esma Dervisevic, Sammy Alhassen, Muamer Dervisevic, Amal Alachkar, Victor J Cadarso, Nicolas H Voelcke. Microfluidic Electrochemical Sensor for Cerebrospinal Fluid and Blood Dopamine Detection in a Mouse Model of Parkinson's Disease. Analytical chemistry. vol 92. issue 18. 2021-02-16. PMID:32786441. |
the loss of dopaminergic neurons results in decreased dopamine (da) release in the striatum and thus impaired motor functions. |
2021-02-16 |
2023-08-13 |
mouse |
| Sasha Gorrell, Anne G E Collins, Daniel Le Grange, Tony T Yan. Dopaminergic activity and exercise behavior in anorexia nervosa. OBM neurobiology. vol 4. issue 1. 2021-02-13. PMID:33569542. |
this review describes the role that dopamine serves in maintaining symptoms in the context of anorexia nervosa, and synthesizes current relevant evidence on exercise in an and related dopaminergic activity. |
2021-02-13 |
2023-08-13 |
Not clear |
| Zhen Qiang Zhang, Christian Hölsche. GIP has neuroprotective effects in Alzheimer and Parkinson's disease models. Peptides. vol 125. 2021-02-08. PMID:31705913. |
in parkinson's disease models, motor activity is normalized, dopaminergic neurons are protected, synapse numbers and dopamine levels are maintained. |
2021-02-08 |
2023-08-13 |
mouse |
| Priyankar Sanphui, Anoy Kumar Das, Subhas C Biswa. Forkhead Box O3a requires BAF57, a subunit of chromatin remodeler SWI/SNF complex for induction of p53 up-regulated modulator of apoptosis (Puma) in a model of Parkinson's disease. Journal of neurochemistry. vol 154. issue 5. 2021-02-04. PMID:31971251. |
we exposed neuronal pc12 cells or primary cultures of dopaminergic neurons to 6-hydroxy dopamine (6-ohda) and infused 6-ohda in rat brain to develop pd models. |
2021-02-04 |
2023-08-13 |
rat |
| Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Honami Setoyama, Yunsu Hwang, Akihiro Yamanaka, Tomoyuki Kuwak. Involvement of A13 dopaminergic neurons located in the zona incerta in nociceptive processing: a fiber photometry study. Molecular brain. vol 13. issue 1. 2021-02-03. PMID:32290851. |
adeno-associated viruses (aav-cag-flex-g-camp6 and aav-cag-flex-mcherry) were unilaterally injected into the a13 site in transgenic mice carrying a dopamine transporter promotor-regulated cre recombinase transgene to specifically introduce g-camp6/mcherry into a13 dopaminergic cell bodies through site-specific infection. |
2021-02-03 |
2023-08-13 |
mouse |
| Sachiko Noda, Shigeto Sato, Takahiro Fukuda, Norihiro Tada, Nobutaka Hattor. Aging-related motor function and dopaminergic neuronal loss in C57BL/6 mice. Molecular brain. vol 13. issue 1. 2021-02-03. PMID:32293495. |
thus, dopamine levels are affected by the loss of dopaminergic neurons. |
2021-02-03 |
2023-08-13 |
mouse |
| María-de-Los-Angeles Andrade-Oliva, Juan Escamilla-Sánchez, Yazmín Debray-García, Russell A Morales-Rubio, Raúl González-Pantoja, Marisela Uribe-Ramírez, Omar Amador-Muñoz, Raúl V Díaz-Godoy, Andrea De Vizcaya-Ruiz, José-Antonio Arias-Montañ. In vitro exposure to ambient fine and ultrafine particles alters dopamine uptake and release, and D Environmental toxicology and pharmacology. vol 80. 2021-02-03. PMID:32942001. |
in vitro exposure to ambient fine and ultrafine particles alters dopamine uptake and release, and d the exposure to environmental pollutants, such as fine and ultrafine particles (fp and ufp), has been associated with increased risk for parkinson's disease, depression and schizophrenia, disorders related to altered dopaminergic transmission. |
2021-02-03 |
2023-08-13 |
Not clear |
| María-de-Los-Angeles Andrade-Oliva, Juan Escamilla-Sánchez, Yazmín Debray-García, Russell A Morales-Rubio, Raúl González-Pantoja, Marisela Uribe-Ramírez, Omar Amador-Muñoz, Raúl V Díaz-Godoy, Andrea De Vizcaya-Ruiz, José-Antonio Arias-Montañ. In vitro exposure to ambient fine and ultrafine particles alters dopamine uptake and release, and D Environmental toxicology and pharmacology. vol 80. 2021-02-03. PMID:32942001. |
the striatum, a neuronal nucleus with extensive dopaminergic afferents, is a target site for particle toxicity, which results in oxidative stress, inflammation, astrocyte activation and modifications in dopamine content and d |
2021-02-03 |
2023-08-13 |
Not clear |
| R N Lippert, S Hess, P Klemm, L M Burgeno, T Jahans-Price, M E Walton, P Kloppenburg, J C Brünin. Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice. The Journal of clinical investigation. vol 130. issue 7. 2021-02-02. PMID:32510473. |
this translated into silencing of dopaminergic midbrain neurons, reduced connectivity to their downstream targets, and reduced stimulus-evoked dopamine (da) release in the striatum. |
2021-02-02 |
2023-08-13 |
mouse |
| Kathleen Wiencke, Annette Horstmann, David Mathar, Arno Villringer, Jane Neuman. Dopamine release, diffusion and uptake: A computational model for synaptic and volume transmission. PLoS computational biology. vol 16. issue 11. 2021-01-29. PMID:33253315. |
signal variability in target areas of dopaminergic neurons (striatum, cortex) may arise from dopamine concentration variability. |
2021-01-29 |
2023-08-13 |
Not clear |
| Kathleen Wiencke, Annette Horstmann, David Mathar, Arno Villringer, Jane Neuman. Dopamine release, diffusion and uptake: A computational model for synaptic and volume transmission. PLoS computational biology. vol 16. issue 11. 2021-01-29. PMID:33253315. |
specifically, dopaminergic tone is assumed to impact on phasic dopamine and hence on the integration of reward-related signals. |
2021-01-29 |
2023-08-13 |
Not clear |
| Agnese Gugliandolo, Federica Pollastro, Placido Bramanti, Emanuela Mazzo. Cannabidiol exerts protective effects in an in vitro model of Parkinson's disease activating AKT/mTOR pathway. Fitoterapia. vol 143. 2021-01-27. PMID:32184097. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by the degeneration of the nigrostriatal dopaminergic pathway with loss of substantia nigra pars compacta neurons and dopamine depletion. |
2021-01-27 |
2023-08-13 |
Not clear |
| T S Pronina, A A Kolacheva, L K Dil'muhametova, Yu O Nikishina, K K Suhinich, M V Ugrumo. Characteristic of Dopamine-Producing System and Dopamine Receptors in the Suprachiasmatic Nucleus in Rats in Ontogenesis. Doklady. Biochemistry and biophysics. vol 490. issue 1. 2021-01-26. PMID:32342310. |
one of the features of the developing suprachiasmatic nucleus (scn), the "biological clock" of the body, is the early expression of dopamine (da) receptors in the absence of dopaminergic neurons as a source of da. |
2021-01-26 |
2023-08-13 |
rat |
| Patrycja Kupnicka, Klaudyna Kojder, Emilia Metryka, Patrycja Kapczuk, Dariusz Jeżewski, Izabela Gutowska, Marta Goschorska, Dariusz Chlubek, Irena Baranowska-Bosiack. Morphine-element interactions - The influence of selected chemical elements on neural pathways associated with addiction. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 60. 2021-01-25. PMID:32179426. |
mesolimbic and mesocortical dopaminergic pathways play an important role in modulation of cognitive processes and decision making and, therefore, changes in dopamine metabolism are considered the central basis for the development of dependence. |
2021-01-25 |
2023-08-13 |
Not clear |
| Fangmiao Sun, Jingheng Zhou, Bing Dai, Tongrui Qian, Jianzhi Zeng, Xuelin Li, Yizhou Zhuo, Yajun Zhang, Yipan Wang, Cheng Qian, Ke Tan, Jiesi Feng, Hui Dong, Dayu Lin, Guohong Cui, Yulong L. Next-generation GRAB sensors for monitoring dopaminergic activity in vivo. Nature methods. vol 17. issue 11. 2021-01-25. PMID:33087905. |
dopamine (da) plays a critical role in the brain, and the ability to directly measure dopaminergic activity is essential for understanding its physiological functions. |
2021-01-25 |
2023-08-13 |
Not clear |
| Wen-Wen Liu, Shi-Zhuang Wei, Guo-Dong Huang, Lu-Bing Liu, Chao Gu, Yun Shen, Xian-Hui Wang, Shu-Ting Xia, An-Mu Xie, Li-Fang Hu, Fen Wang, Chun-Feng Li. BMAL1 regulation of microglia-mediated neuroinflammation in MPTP-induced Parkinson's disease mouse model. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 5. 2021-01-22. PMID:32246801. |
we here showed that inactivation of brain and muscle arnt-like 1 (bmal1) in 1-methyl-4-phenyl-1,2,4,5-tetrahydropyridine (mptp)-treated mice resulted in obvious motor functional deficit, loss of dopaminergic neurons (dans) in the substantia nigra pars compacta (snpc), decrease of dopamine (da) transmitter, and increased activation of microglia and astrocytes in the striatum. |
2021-01-22 |
2023-08-13 |
mouse |
| Joseph Jankovic, Eng King Ta. Parkinson's disease: etiopathogenesis and treatment. Journal of neurology, neurosurgery, and psychiatry. vol 91. issue 8. 2021-01-19. PMID:32576618. |
the involvement of dopaminergic as well as noradrenergic, glutamatergic, serotonergic and adenosine pathways provide insights into the rich and variable clinical phenomenology associated with pd and the possibility of alternative therapeutic approaches beyond traditional dopamine replacement therapies.one of the biggest challenges in the development of potential neuroprotective therapies has been the lack of reliable and sensitive biomarkers of progression. |
2021-01-19 |
2023-08-13 |
Not clear |
| Bianca L B Marino, Lucilene R de Souza, Kessia P A Sousa, Jaderson V Ferreira, Elias C Padilha, Carlos H T P da Silva, Carlton A Taft, Lorane I S Hage-Meli. Parkinson's Disease: A Review from Pathophysiology to Treatment. Mini reviews in medicinal chemistry. vol 20. issue 9. 2021-01-15. PMID:31686637. |
pd is caused by the necrosis of dopaminergic neurons in the substantia nigra, which is the brain region responsible for the synthesis of the neurotransmitter dopamine (da), resulting in its decrease in the synaptic cleft. |
2021-01-15 |
2023-08-13 |
Not clear |
| Wanpeng Cui, Tomomi Aida, Hikaru Ito, Kenta Kobayashi, Yusaku Wada, Shigeki Kato, Takashi Nakano, Meina Zhu, Kaoru Isa, Kazuto Kobayashi, Tadashi Isa, Kohichi Tanaka, Hidenori Aizaw. Dopaminergic Signaling in the Nucleus Accumbens Modulates Stress-Coping Strategies during Inescapable Stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 38. 2021-01-15. PMID:32847967. |
to investigate how dopamine signaling modulates stress-coping behavior, we measured the subsecond fluctuation of extracellular dopamine concentration and ph using fast scanning cyclic voltammetry (fscv) in the nac, a postsynaptic target of midbrain dopaminergic neurons, in male mice engaged in a tail suspension test (tst). |
2021-01-15 |
2023-08-13 |
mouse |