| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Collins, L S Wilkinson, B J Everitt, T W Robbins, A C Robert. The effect of dopamine depletion from the caudate nucleus of the common marmoset (Callithrix jacchus) on tests of prefrontal cognitive function. Behavioral neuroscience. vol 114. issue 1. 2000-04-19. PMID:10718258. |
though it is not possible to identify specific cognitive functions that are independent of dopaminergic modulation of the caudate nucleus, due to the partial nature of the lesion, the results do provide insight into those cognitive processes that appear most dependent on caudate dopamine. |
2000-04-19 |
2023-08-12 |
marmoset |
| E Koga, T Momiyam. Presynaptic dopamine D2-like receptors inhibit excitatory transmission onto rat ventral tegmental dopaminergic neurones. The Journal of physiology. vol 523 Pt 1. 2000-04-18. PMID:10673553. |
the effects of dopamine (da) on non-nmda glutamatergic transmission onto dopaminergic neurones in the ventral tegmental area (vta) were examined in rat midbrain slices using the whole-cell patch-clamp technique. |
2000-04-18 |
2023-08-12 |
rat |
| L Antkiewicz-Michaluk, I Romañska, I Papla, J Michaluk, M Bakalarz, J Vetulani, A Krygowska-Wajs, A Szczudli. Neurochemical changes induced by acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain. Neuroscience. vol 96. issue 1. 2000-04-17. PMID:10683410. |
we tested, using a high-performance liquid chromatography method, how single and chronic administration of 1,2, 3,4-tetrahydroisoquinoline and salsolinol affects dopamine and serotonin metabolism in the neurons of extrapyramidal and mesolimbic dopaminergic systems. |
2000-04-17 |
2023-08-12 |
rat |
| W Schütz, T Anhäupl, A Gaus. [Principles of catecholamine therapy. 1. Characterization of clinically relevant sympathomimetics]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. vol 35. issue 2. 2000-04-13. PMID:10719595. |
adrenaline, noradrenaline and dopamine are endogenous catecholamines binding to adrenergic and dopaminergic receptors, respectively, to mediate their clinical effects. |
2000-04-13 |
2023-08-12 |
Not clear |
| W Schütz, T Anhäupl, A Gaus. [Principles of catecholamine therapy. 1. Characterization of clinically relevant sympathomimetics]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. vol 35. issue 2. 2000-04-13. PMID:10719595. |
dopamine, less potent on adrenoceptors, shows additional effects on renal as well as on splanchnic circulation mediated by dopaminergic receptors. |
2000-04-13 |
2023-08-12 |
Not clear |
| P G Clifto. Meal patterning in rodents: psychopharmacological and neuroanatomical studies. Neuroscience and biobehavioral reviews. vol 24. issue 2. 2000-04-11. PMID:10714384. |
analysis of dopaminergic mechanisms show that dopamine d2 receptor blockade is associated with enhancement of meal size and decrease of meal frequency; this probably represents a failure to switch from feeding to other behaviour when a meal is expected to terminate. |
2000-04-11 |
2023-08-12 |
Not clear |
| Y S Ding, J Logan, R Bermel, V Garza, O Rice, J S Fowler, N D Volko. Dopamine receptor-mediated regulation of striatal cholinergic activity: positron emission tomography studies with norchloro[18F]fluoroepibatidine. Journal of neurochemistry. vol 74. issue 4. 2000-04-11. PMID:10737608. |
large numbers of in vitro studies and microdialysis studies suggest that dopaminergic regulation of striatal acetylcholine (ach) output is via inhibitory dopamine d2 receptors and stimulatory dopamine d1 receptors. |
2000-04-11 |
2023-08-12 |
Not clear |
| F I Tarazi, R J Baldessarin. Regional localization of dopamine and ionotropic glutamate receptor subtypes in striatolimbic brain regions. Journal of neuroscience research. vol 55. issue 4. 2000-03-29. PMID:10723051. |
degeneration of nigrostriatal dopamine projections with 6-hydroxydopamine showed that all three glutamatergic subtypes exist as heteroceptors on nigrostriatal dopaminergic terminals. |
2000-03-29 |
2023-08-12 |
rat |
| R Pawlak, Y Takada, H Takahashi, T Urano, H Ihara, N Nagai, A Takad. Differential effects of nicotine against stress-induced changes in dopaminergic system in rat striatum and hippocampus. European journal of pharmacology. vol 387. issue 2. 2000-03-28. PMID:10650157. |
since it is well known that nicotine or stress alter the dopaminergic system, we examined the effect of chronic nicotine administration on the dopamine level and its metabolism in the striatum and the hippocampus during stressful conditions in rats. |
2000-03-28 |
2023-08-12 |
rat |
| J A Schafer, L Li, D Su. The collecting duct, dopamine and vasopressin-dependent hypertension. Acta physiologica Scandinavica. vol 168. issue 1. 2000-03-27. PMID:10691807. |
the only dopaminergic antagonist that reversed the inhibitory effect of dopamine was clozapine, which is relatively d4-specific. |
2000-03-27 |
2023-08-12 |
rat |
| R A Felder, G M Eisner, P A Jos. D1 dopamine receptor signalling defect in spontaneous hypertension. Acta physiologica Scandinavica. vol 168. issue 1. 2000-03-27. PMID:10691808. |
the molecular basis for the dopaminergic dysfunction in hypertension may involve an abnormal post-translational modification of dopamine receptors. |
2000-03-27 |
2023-08-12 |
Not clear |
| J L Venero, M L Vizuete, M Revuelta, C Vargas, J Cano, A Machad. Upregulation of BDNF mRNA and trkB mRNA in the nigrostriatal system and in the lesion site following unilateral transection of the medial forebrain bundle. Experimental neurology. vol 161. issue 1. 2000-03-23. PMID:10683272. |
the disposition of bdnf mrna expressing cells at this postlesion time in substantia nigra mimicked that of the dopaminergic neurons expressing the mrna for the dopamine transporter. |
2000-03-23 |
2023-08-12 |
Not clear |
| F X Vollenweider, P Vontobel, I Oye, D Hell, K L Leender. Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans. Journal of psychiatric research. vol 34. issue 1. 2000-03-23. PMID:10696831. |
given the clinical efficacy of dopamine (da) d2 receptor antagonists in the treatment of positive symptoms, it is conceivable that s-ketamine-induced psychotic symptoms are partially due to a secondary activation of dopaminergic systems. |
2000-03-23 |
2023-08-12 |
human |
| C Haubrich, V Frielingsdorf, S Herzig, H Schröder, R Schwarting, V Sturm, J Voge. N-type calcium channel blockers - tools for modulation of cerebral functional units? Brain research. vol 855. issue 2. 2000-03-21. PMID:10677594. |
time course and reversibility of neurological deficits caused by omega-ctx, as well as a lack of dopamine depletion contrast findings after selective destruction of dopaminergic neurons and support a functional modulation of dopaminergic transmission. |
2000-03-21 |
2023-08-12 |
rat |
| P Padungchaichot, J Y Wong, A L Natoli, J S Massalas, D I Finkelstein, A L Lawrence, J Drag. Early direct and transneuronal effects in mice with targeted expression of a toxin gene to D1 dopamine receptor neurons. Neuroscience. vol 95. issue 4. 2000-03-21. PMID:10682709. |
the nigrostriatal pathway in the mutant pups was intact with a normal number of dopaminergic neurons in the substantia nigra and the ventral tegmental area in addition to a normal pattern of striatal dopamine transporter and tyrosine hydroxylase immunoreactivity. |
2000-03-21 |
2023-08-12 |
mouse |
| P Franke, M M Nöthen, T Wang, M Knapp, D Lichtermann, H Neidt, T Sander, P Propping, W Maie. DRD4 exon III VNTR polymorphism-susceptibility factor for heroin dependence? Results of a case-control and a family-based association approach. Molecular psychiatry. vol 5. issue 1. 2000-03-17. PMID:10673776. |
dopaminergic abnormalities are implicated in the pathogenesis of substance abuse.1 recently, two reports have been published suggesting an association between opioid dependence and presence of long alleles of the dopamine d4 receptor (drd4) gene exon iii vntr.2, 3 we have attempted to replicate this finding using a two-tiered strategy employing independent case-control and family-based association samples. |
2000-03-17 |
2023-08-12 |
human |
| S E Ustinova, E V Iarnykh, V P Masenko, G G Arabidz. [Features of dopaminergic system function in menopausal females with arterial hypertension]. Terapevticheskii arkhiv. vol 72. issue 1. 2000-03-17. PMID:10687204. |
assessment of dopaminergic activity by changes in urine excretion of dopamine, arterial hypertension, blood prolactine, 24-h diuresis and natriuresis in response to a single (2.5 mg) and 7-day (daily dose 5 mg) administration of parlodel in patients with essential hypertension (eh) in menopausal and reproductive age having different serum levels of estrogens. |
2000-03-17 |
2023-08-12 |
Not clear |
| G Zauli, P Secchiero, L Rodella, D Gibellini, P Mirandola, M Mazzoni, D Milani, D R Dowd, S Capitani, M Vital. HIV-1 Tat-mediated inhibition of the tyrosine hydroxylase gene expression in dopaminergic neuronal cells. The Journal of biological chemistry. vol 275. issue 6. 2000-03-16. PMID:10660577. |
treatment of dopaminergic rat pc12 cells with human immunodeficiency virus, type 1 (hiv-1) tat protein or tat cdna inhibited the expression of tyrosine hydroxylase (th), the rate-limiting enzyme for the dopamine biosynthetic pathway, as well as the production and release of dopamine into the culture medium. |
2000-03-16 |
2023-08-12 |
human |
| A Molina-Hernández, A Nuñez, J A Arias-Montañ. Histamine H3-receptor activation inhibits dopamine synthesis in rat striatum. Neuroreport. vol 11. issue 1. 2000-03-16. PMID:10683850. |
taken together, our results indicate that histamine modulates striatal dopamine synthesis by acting at h3-receptors located on dopaminergic nerve terminals. |
2000-03-16 |
2023-08-12 |
rat |
| A M Lin, T Y Luh, C K Chou, L T H. The antioxidative effect of carboxyfullerenes (C3/D3) on iron-induced oxidative injury in CNS. Annals of the New York Academy of Sciences. vol 890. 2000-03-15. PMID:10668440. |
in urethane-anesthetized rats, intranigral infusion of iron degenerated the nigrostriatal dopaminergic system, including as elevation in lipid peroxidation in the infused substantia nigra (sn) and reductions in k(+)-evoked dopamine overflow and dopamine content in the ipsilateral striatum 7 days after the infusion. |
2000-03-15 |
2023-08-12 |
rat |