| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Guyon, D Skrzydelski, I De Giry, C Rovère, G Conductier, J M Trocello, V Daugé, P Kitabgi, W Rostène, J L Nahon, S Mélik Parsadaniant. Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19477239. |
we provide here the first evidence that application of ccl2 on dopaminergic neurons increases their excitability, dopamine release and related locomotor activity. |
2009-11-10 |
2023-08-12 |
rat |
| Zhihua Xie, Gregory M Mille. Trace amine-associated receptor 1 as a monoaminergic modulator in brain. Biochemical pharmacology. vol 78. issue 9. 2009-11-10. PMID:19482011. |
taar1 is expressed and widely distributed in brain monoaminergic systems and co-localized with the dopamine transporter in a subset of dopaminergic neurons in rhesus monkey and mouse brain substantia nigra. |
2009-11-10 |
2023-08-12 |
mouse |
| Francesca Cicchetti, Janelle Drouin-Ouellet, Robert E Gros. Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models? Trends in pharmacological sciences. vol 30. issue 9. 2009-11-09. PMID:19729209. |
pathologically, most motor features are the result of a dramatic loss of ventral tier mesencephalic dopaminergic neurons and thus dopamine content at their target sites. |
2009-11-09 |
2023-08-12 |
Not clear |
| Jin Young Shin, Hyun-Jung Park, Young Hwan Ahn, Phil Hyu Le. Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. Journal of neurochemistry. vol 111. issue 4. 2009-11-06. PMID:19765187. |
in this study, to determine whether l-dopa is toxic or dopamine agonist is neuroprotective to dopaminergic neurons, we evaluated the neuroprotective properties of l-dopa and the pramipexol (ppx), one of dopamine agonists, with a focus on the regulatory effects of the anti-oxidant properties and cell survival or apoptotic signal pathways in the same experimental design, using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-treated pd animals. |
2009-11-06 |
2023-08-12 |
mouse |
| Shuang Liu, Zengmin Tian, Feng Yin, Quanjun Zhao, Ming Fa. Generation of dopaminergic neurons from human fetal mesencephalic progenitors after co-culture with striatal-conditioned media and exposure to lowered oxygen. Brain research bulletin. vol 80. issue 1-2. 2009-11-02. PMID:19463914. |
lowered o(2) significantly induced mrna expression of erythropoietin (epo) and p27, which affect neuronal differentiation, and was accompanied by upregulation of nurr1, pitx3 and dopamine transporter (dat) mrnas, which are correlated to the maturation of dopaminergic neurons. |
2009-11-02 |
2023-08-12 |
human |
| Gareth O Minton, Allan H Young, Richard McQuade, Graeme Fairchild, Colin D Ingram, Sarah E Gartsid. Profound changes in dopaminergic neurotransmission in the prefrontal cortex in response to flattening of the diurnal glucocorticoid rhythm: implications for bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 10. 2009-10-29. PMID:19494803. |
to address this hypothesis, we investigated the effects of a flattened glucocorticoid rhythm on (i) the release of dopamine in the pfc and (ii) the transcription of genes in the ventral tegmental area (vta) coding for proteins involved in presynaptic aspects of dopaminergic neurotransmission. |
2009-10-29 |
2023-08-12 |
rat |
| Pol Giménez-Xavier, Roser Francisco, Antonio F Santidrián, Joan Gil, Santiago Ambrosi. Effects of dopamine on LC3-II activation as a marker of autophagy in a neuroblastoma cell model. Neurotoxicology. vol 30. issue 4. 2009-10-27. PMID:19410601. |
as we have reported previously, cytosolic dopamine may cause damage by autophagy in neuroblastoma cells (and presumably in dopaminergic neurons), which develops to apoptosis and leads to cell degeneration. |
2009-10-27 |
2023-08-12 |
human |
| Ilana Roth-Deri, Alexander Friedman, Lital Abraham, Elad Lax, Yakov Flaumenhaft, Yahav Dikshtein, Gal Yadi. Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression. The European journal of neuroscience. vol 30. issue 3. 2009-10-27. PMID:19614746. |
in light of dopamine's central role in modulating cocaine reinforcement, we examined dopaminergic neurotransmission in the nucleus accumbens, a brain region implicated in the rewarding and hedonic effects of substances of misuse. |
2009-10-27 |
2023-08-12 |
rat |
| Philip Seeman, Kenichi Tokita, Mitsuyuki Matsumoto, Ayako Matsuo, Masao Sasamata, Keiji Miyat. The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19588469. |
dopaminergic stabilizers are recognized as compounds that can either enhance or antagonize dopamine (da)-dependent behaviors depending on the prevailing dopaminergic tone. |
2009-10-26 |
2023-08-12 |
human |
| Philip Seeman, Kenichi Tokita, Mitsuyuki Matsumoto, Ayako Matsuo, Masao Sasamata, Keiji Miyat. The dopaminergic stabilizer ASP2314/ACR16 selectively interacts with D2(High) receptors. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19588469. |
to elucidate the mechanisms of action of this dopaminergic stabilizer, its potency on the functional dopamine d2(high) receptors was examined. |
2009-10-26 |
2023-08-12 |
human |
| Cheryse A Furman, Charles B Lo, Stephanie Stokes, Jose A Esteban, Margaret E Gneg. Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells. Neuroscience letters. vol 463. issue 1. 2009-10-23. PMID:19631257. |
the dopamine transporter (dat) is a crucial regulator of dopaminergic neurotransmission which undergoes constitutive and substrate-mediated trafficking to and from the membrane. |
2009-10-23 |
2023-08-12 |
Not clear |
| Amira Taman, Paula Ribeir. Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalization. Molecular and biochemical parasitology. vol 168. issue 1. 2009-10-16. PMID:19545592. |
pharmacological studies showed that the s. mansoni dopamine receptor was inhibited by apomorphine, a classical dopamine agonist, as well as known dopaminergic antagonists, including chlorpromazine, spiperone and haloperidol. |
2009-10-16 |
2023-08-12 |
Not clear |
| Aroa Soriano, Ruben Ventura, Anabel Molero, Rob Hoen, Vicent Casadó, Antoni Cortés, Francesca Fanelli, Fernando Albericio, Carmen Lluís, Rafael Franco, Miriam Roy. Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers. Journal of medicinal chemistry. vol 52. issue 18. 2009-10-14. PMID:19711895. |
adenosine a(2a) (a(2a)r) and dopamine d(2) (d(2)r) receptors mediate the antagonism between adenosinergic and dopaminergic transmission in striatopallidal gabaergic neurons and are pharmacological targets for the treatment of parkinson's disease. |
2009-10-14 |
2023-08-12 |
Not clear |
| Xiangqian Liu, Linda Chang, Michael Vigorito, Marley Kass, He Li, Sulie L Chan. Methamphetamine-induced behavioral sensitization is enhanced in the HIV-1 transgenic rat. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 4. issue 3. 2009-10-13. PMID:19444617. |
the involvement of the dopaminergic system was investigated by examining dopamine receptors 1 (d1r) and 2 (d2r) and dopamine transporter (dat) expression in the striatum and prefrontal cortex. |
2009-10-13 |
2023-08-12 |
rat |
| Ranjeet Verma, Bimla Nehr. Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease. Neurochemistry international. vol 55. issue 6. 2009-10-09. PMID:19375462. |
the important biochemical features of pd, being profound deficit in dopamine (da) content, reduced glutathione (gsh), and enhanced lipid peroxidation (lpo) in dopaminergic (da-ergic) neurons resulting in oxidative stress, mitochondrial dysfunction and apoptosis. |
2009-10-09 |
2023-08-12 |
rat |
| Jiaqian Ren, Haibo Xu, Ji-Kyung Choi, Bruce G Jenkins, Y Iris Che. Dopaminergic response to graded dopamine concentration elicited by four amphetamine doses. Synapse (New York, N.Y.). vol 63. issue 9. 2009-10-09. PMID:19484725. |
dopaminergic response to graded dopamine concentration elicited by four amphetamine doses. |
2009-10-09 |
2023-08-12 |
Not clear |
| Alicja Sieminska, Krzysztof Buczkowski, Ewa Jassem, Marek Niedoszytko, Ewa Tkac. Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population. BMC medical genetics. vol 10. 2009-10-09. PMID:19761593. |
polymorphisms in dopaminergic genes may influence cigarette smoking by their potential impact on dopamine reward pathway function. |
2009-10-09 |
2023-08-12 |
Not clear |
| E Chris Muly, Murat Senyuz, Zafar U Khan, Ji-Dong Guo, Rimi Hazra, Donald G Rainni. Distribution of D1 and D5 dopamine receptors in the primate and rat basolateral amygdala. Brain structure & function. vol 213. issue 4-5. 2009-10-08. PMID:19669160. |
the higher affinity of d(5) for dopamine suggests that presynaptic actions may predominate in the bla at low levels of dopamine, while postsynaptic effects increase and dominate as dopaminergic drive increases. |
2009-10-08 |
2023-08-12 |
rat |
| E Chris Muly, Murat Senyuz, Zafar U Khan, Ji-Dong Guo, Rimi Hazra, Donald G Rainni. Distribution of D1 and D5 dopamine receptors in the primate and rat basolateral amygdala. Brain structure & function. vol 213. issue 4-5. 2009-10-08. PMID:19669160. |
the results presented here suggest a complex action of dopamine on bla circuitry that may evolve with different degrees of dopaminergic stimulation. |
2009-10-08 |
2023-08-12 |
rat |
| Anna Paschali, Velissarios Lakiotis, Lambros Messinis, Elli Markaki, Constantine Constantoyannis, John Ellul, Pavlos Vassilako. Dopamine transporter SPECT/CT and perfusion brain SPECT imaging in idiopathic basal ganglia calcinosis. Clinical nuclear medicine. vol 34. issue 7. 2009-09-30. PMID:19542944. |
the nigrostriatal dopaminergic pathway and regional cerebral blood flow were evaluated using dopamine transporter (dat) brain single photon emission tomography combined with a low-dose x-ray computerized tomography transmission (hybrid spect/ct) and tc-99m hmpao brain perfusion spect study, respectively. |
2009-09-30 |
2023-08-12 |
Not clear |