| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karl Ekbom, J Ulfber. Restless legs syndrome. Journal of internal medicine. vol 266. issue 5. 2009-12-07. PMID:19817966. |
however, advanced brain imaging studies and positive results of dopaminergic treatment suggest that rls may be generated by dopamine dysfunction locally within the central nervous system. |
2009-12-07 |
2023-08-12 |
Not clear |
| Afsaneh Gaillard, Mickael Decressac, Isabelle Frappé, Pierre Olivier Fernagut, Laetitia Prestoz, Stephan Besnard, Mohamed Jabe. Anatomical and functional reconstruction of the nigrostriatal pathway by intranigral transplants. Neurobiology of disease. vol 35. issue 3. 2009-12-03. PMID:19616502. |
grafted cells integrated within the host mesencephalon and expressed the dopaminergic markers tyrosine hydroxylase, vesicular monoamine transporter 2 and dopamine transporter. |
2009-12-03 |
2023-08-12 |
mouse |
| Hiroshi Ito, Harumasa Takano, Hidehiko Takahashi, Ryosuke Arakawa, Michie Miyoshi, Fumitoshi Kodaka, Masaki Okumura, Tatsui Otsuka, Tetsuya Suhar. Effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with L-[beta-11C]DOPA: a stabilizing effect for dopaminergic neurotransmission? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 43. 2009-12-02. PMID:19864585. |
effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with l-[beta-11c]dopa: a stabilizing effect for dopaminergic neurotransmission? |
2009-12-02 |
2023-08-12 |
human |
| Hiroshi Ito, Harumasa Takano, Hidehiko Takahashi, Ryosuke Arakawa, Michie Miyoshi, Fumitoshi Kodaka, Masaki Okumura, Tatsui Otsuka, Tetsuya Suhar. Effects of the antipsychotic risperidone on dopamine synthesis in human brain measured by positron emission tomography with L-[beta-11C]DOPA: a stabilizing effect for dopaminergic neurotransmission? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 43. 2009-12-02. PMID:19864585. |
to investigate the effects of antipsychotics on presynaptic functions of dopaminergic neurotransmission in relation with occupancy of dopamine d(2) receptors, changes in dopamine synthesis capacity by antipsychotics and occupancy of dopamine d(2) receptors were measured by positron emission tomography (pet) in healthy men. |
2009-12-02 |
2023-08-12 |
human |
| Amy M Knab, Robert S Bowen, Alicia T Hamilton, Alyssa A Gulledge, J Timothy Lightfoo. Altered dopaminergic profiles: implications for the regulation of voluntary physical activity. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19520120. |
these results indicate that decreased dopaminergic functioning is correlated with increased activity levels in c57l/j mice and suggests that d1-like receptors as well as tyrosine hydroxylase (an indicator of dopamine production), but not d2-like receptors may be associated with the regulation of physical activity in inbred mice. |
2009-12-01 |
2023-08-12 |
mouse |
| Susanne Nikolaus, Christina Antke, Hans-Wilhelm Mülle. In vivo imaging of synaptic function in the central nervous system: I. Movement disorders and dementia. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19523490. |
in the majority of investigations on patients with alzheimer's disease, no alterations of presynaptic dopamine function were found, whereas all other forms of dementia including corticobasal degeneration, dementia with lewy bodies, parkinson's disease dementia and frontotemporal dementia were characterized by presynaptic dopaminergic deficiencies with reductions in striatal dopamine synthesis (10 out of a total of 10 reports on these types of dementia), storage (four out of four reports) and transporter binding (29 out of 29 reports). |
2009-12-01 |
2023-08-12 |
Not clear |
| Susanne Nikolaus, Christina Antke, Hans-Wilhelm Mülle. In vivo imaging of synaptic function in the central nervous system: II. Mental and affective disorders. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19523495. |
results on both dopaminergic and serotonergic neurotransmission are inconsistent in both major depressive disorder and bipolar illness, and fail to clearly agree with the dopamine and/or serotonin hypothesis of depression. |
2009-12-01 |
2023-08-12 |
human |
| Susanne Nikolaus, Christina Antke, Hans-Wilhelm Mülle. In vivo imaging of synaptic function in the central nervous system: II. Mental and affective disorders. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19523495. |
these findings as well as the reduction of striatal dopamine release observed in adults (merely 1 report) are in line with the notion of mesocortical dopaminergic hypofunction in attention-deficit/hyperactivity disorder. |
2009-12-01 |
2023-08-12 |
human |
| O S Levin, O S Nesterova, O V Otcheskaia, E Iu Zhuravleva, I Iu Artemova, A A Khozova, A M Ismailov, L N Lisenker, T V Vdovichenko, L D Rotor, P A Ganzula, A K Ivanov, A N Boĭk. [Influence of dopamine agonist pramipexole (mirapex) on tremor, cognitive and affective impairment in patients with Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 109. issue 8. 2009-12-01. PMID:19738567. |
the open 3-month study of influence of d2/d3 dopamine agonist pramipexole on of parkinson's disease (pd) features, which are relatively resistant to traditional dopaminergic therapy: tremor, affective and cognitive impairment, has been conducted. |
2009-12-01 |
2023-08-12 |
Not clear |
| Dingzhen Luo, Quanbin Zhang, Haomin Wang, Yanqiu Cui, Zuoli Sun, Jian Yang, Yan Zheng, Jun Jia, Fen Yu, Xuan Wang, Xiaomin Wan. Fucoidan protects against dopaminergic neuron death in vivo and in vitro. European journal of pharmacology. vol 617. issue 1-3. 2009-11-30. PMID:19545563. |
here we investigated the effect of fucoidan treatment on locomoter activities of animals, striatal dopamine and its metabolites and survival of nigral dopaminergic neurons in mptp-induced animal model of parkinsonism in c57/bl mice in vivo and on the neuronal damage induced by 1-methyl-4-phenylpyridinium (mpp(+)) in vitro, and to study the possible mechanisms. |
2009-11-30 |
2023-08-12 |
mouse |
| C Pellicano, F R Buttarelli, A Circella, D Tiple, M Giovannelli, D Benincasa, C Colosimo, F E Pontier. Dopamine transporter immunoreactivity in peripheral blood lymphocytes discriminates Parkinson's disease from essential tremor. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 7. 2009-11-23. PMID:17260170. |
in this study, densitometric analysis was applied to measure dopamine transporter (dat) immunoreactivity in pbl from dopaminergic drug-free patients suffering pd or essential tremor (et) with respect to healthy subjects. |
2009-11-23 |
2023-08-12 |
human |
| Rachel Scornaiencki, Robert Cantrup, Walter J Rushlow, Nagalingam Rajakuma. Prefrontal cortical D1 dopamine receptors modulate subcortical D2 dopamine receptor-mediated stress responsiveness. The international journal of neuropsychopharmacology. vol 12. issue 9. 2009-11-23. PMID:19275776. |
decreased dopaminergic activity and loss of dopamine fibres have been reported in pfc in schizophrenia patients. |
2009-11-23 |
2023-08-12 |
rat |
| Rachel Scornaiencki, Robert Cantrup, Walter J Rushlow, Nagalingam Rajakuma. Prefrontal cortical D1 dopamine receptors modulate subcortical D2 dopamine receptor-mediated stress responsiveness. The international journal of neuropsychopharmacology. vol 12. issue 9. 2009-11-23. PMID:19275776. |
the results suggest that dopaminergic transmission via d1 receptors in the mpfc modulates d2 dopamine receptor-mediated stress responsiveness in the nac, a feature that may be disrupted in schizophrenia patients. |
2009-11-23 |
2023-08-12 |
rat |
| A H V Schapira, M Emre, P Jenner, W Poew. Levodopa in the treatment of Parkinson's disease. European journal of neurology. vol 16. issue 9. 2009-11-17. PMID:19538218. |
the predominant motor features of parkinson's disease (pd) are caused by degeneration of dopaminergic neurones and can be reversed in part or whole by dopamine replacement or augmentation strategies. |
2009-11-17 |
2023-08-12 |
Not clear |
| Daniel C Javit. Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions. International review of neurobiology. vol 78. 2009-11-13. PMID:17349858. |
to date, the most widely considered neurochemical hypothesis of schizophrenia is the dopamine hypothesis, which postulates that symptoms of schizophrenia may result from excess dopaminergic neurotransmission particularly in striatal brain regions, along with dopaminergic deficits in prefrontal brain regions. |
2009-11-13 |
2023-08-12 |
Not clear |
| Gerard J Mare. Serotonin and dopamine interactions in rodents and primates: implications for psychosis and antipsychotic drug development. International review of neurobiology. vol 78. 2009-11-13. PMID:17349861. |
further advances along these lines with respect to the dopaminergic and serotonergic neurostransmitter systems will be aided by an appreciation of the interaction between dopamine and serotonin receptor subtypes in a range of key brain structures, such as the prefrontal cortex, thalamus, striatum, amygdala, hippocampus, and the brain stem nuclei, from which the cell bodies of monoaminergic-containing neurons originate. |
2009-11-13 |
2023-08-12 |
Not clear |
| Su Ling Leong, Chi L L Pham, Denise Galatis, Michelle T Fodero-Tavoletti, Keyla Perez, Andrew F Hill, Colin L Masters, Feda E Ali, Kevin J Barnham, Roberto Cappa. Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation. Free radical biology & medicine. vol 46. issue 10. 2009-11-13. PMID:19248830. |
pd involves the loss of dopaminergic neurons in the substantia nigra and the subsequent depletion of dopamine (da) in the striatum. |
2009-11-13 |
2023-08-12 |
Not clear |
| Bing Yao, Raymond C Harris, Ming-Zhi Zhan. Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway. Hypertension (Dallas, Tex. : 1979). vol 54. issue 5. 2009-11-12. PMID:19770404. |
locally produced dopamine in the renal proximal tubule inhibits salt and fluid reabsorption, and a dysfunctional intrarenal dopaminergic system has been reported in essential hypertension and experimental hypertension models. |
2009-11-12 |
2023-08-12 |
mouse |
| Diana P Prata, Andrea Mechelli, Marco M Picchioni, Cynthia H Y Fu, Timothea Toulopoulou, Elvira Bramon, Muriel Walshe, Robin M Murray, David A Collier, Philip McGuir. Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia. Archives of general psychiatry. vol 66. issue 11. 2009-11-12. PMID:19884604. |
the dopamine transporter plays a key role in the regulation of central dopaminergic transmission, which modulates cognitive processing. |
2009-11-12 |
2023-08-12 |
Not clear |
| K Mizoguchi, H Shoji, Y Tanaka, W Maruyama, T Tabir. Age-related spatial working memory impairment is caused by prefrontal cortical dopaminergic dysfunction in rats. Neuroscience. vol 162. issue 4. 2009-11-10. PMID:19463906. |
thus, age-related working memory impairment was through reduced pfc dopaminergic transmission caused by decreased dopamine synthesis in the prefrontal termination region, but not at the site where the projections originate. |
2009-11-10 |
2023-08-12 |
human |