| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paolo Barone, Werner Poewe, Stefan Albrecht, Catherine Debieuvre, Dan Massey, Olivier Rascol, Eduardo Tolosa, Daniel Weintrau. Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial. The Lancet. Neurology. vol 9. issue 6. 2010-06-07. PMID:20452823. |
because depression in patients with parkinson's disease might be related to dopaminergic dysfunction, we aimed to assess the efficacy of the dopamine agonist pramipexole for treatment of depressive symptoms in patients with parkinson's disease. |
2010-06-07 |
2023-08-12 |
Not clear |
| Lars Bäckman, Ulman Lindenberger, Shu-Chen Li, Lars Nyber. Linking cognitive aging to alterations in dopamine neurotransmitter functioning: recent data and future avenues. Neuroscience and biobehavioral reviews. vol 34. issue 5. 2010-06-02. PMID:20026186. |
molecular-imaging studies of dopaminergic neurotransmission measure biomarkers of dopamine (da), such as the da transporter and d(1) and d(2) receptor densities in the living brain. |
2010-06-02 |
2023-08-12 |
Not clear |
| Marcello Solinas, Gianluigi Tanda, Carrie E Wertheim, Steven R Goldber. Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D(2)-induced formation of anandamide. Psychopharmacology. vol 209. issue 2. 2010-05-28. PMID:20179908. |
although delta-9-tetreahydrocannabinol (thc)-induced elevations in accumbal dopamine levels are believed to play an important role in the abuse-related effects of cannabis, little direct evidence has been provided that the dopaminergic system is involved in the psychotropic effects of thc. |
2010-05-28 |
2023-08-12 |
Not clear |
| Meg Waraczynski, Jennifer Salemme, Benjamin Farra. Brain stimulation reward is affected by D2 dopamine receptor manipulations in the extended amygdala but not the nucleus accumbens. Behavioural brain research. vol 208. issue 2. 2010-05-25. PMID:20085789. |
these results suggest that dopaminergic neurotransmission in the sleac is more important to reward processes than is dopamine in the nac. |
2010-05-25 |
2023-08-12 |
rat |
| Haja No, Yeojin Bang, Juhee Lim, Sa Suk Kim, Hueng-Sik Choi, Hyun Jin Cho. Involvement of induction and mitochondrial targeting of orphan nuclear receptor Nur77 in 6-OHDA-induced SH-SY5Y cell death. Neurochemistry international. vol 56. issue 4. 2010-05-25. PMID:20096738. |
here we showed that (1) nur77 was up-regulated, phosphorylated, and translocated from the nucleus into the cytosol and mitochondria by h(2)o(2) treatment in hek293 cells, as well as in 6-hydroxy dopamine (6-ohda)-treated dopaminergic sh-sy5y cells, (2) oxidative stress-mediated cell death was exacerbated in nur77-overexpressed cells and abolished by dominant-negative-nur77 transfection, and (3) blockade of nuclear export attenuated 6-ohda-induced sh-sy5y cell death. |
2010-05-25 |
2023-08-12 |
Not clear |
| N Pattarachotanant, T Sritharathikhun, S Suttirat, T Tencomna. Association of C/T polymorphism in intron 14 of the dopamine transporter gene (rs40184) with major depression in a northeastern Thai population. Genetics and molecular research : GMR. vol 9. issue 1. 2010-05-19. PMID:20391341. |
since the dopamine transporter (dat1, also known as slc6a3), mediates the active reuptake of dopamine from the synapses and thereby plays a vital role in the regulation of dopaminergic neurotransmission, we looked for a possible association between the c/t single nucleotide polymorphism in intron 14 of the dat1 gene (also referred to as rs40184) and mdd in a northeastern thai population. |
2010-05-19 |
2023-08-12 |
human |
| A I Davydova, P M Klodt, V S Kudrin, E A Kuznetsova, V B Narkevic. [Neurochemical study of effects of the new anxiolytic drugs afobazol and ladasten on the synthesis and metabolism of monoamines and their metabolites in the brain structures of Wistar rat on the model of monoamine synthesis blockade induced by aromatic amino acid decarboxylase inhibitor NSD-1015]. Eksperimental'naia i klinicheskaia farmakologiia. vol 73. issue 3. 2010-05-19. PMID:20408420. |
ladasten exhibited selectivity with respect to the dopaminergic system and affected only parameters of the dopamine metabolism, in particular, by increasing the hva content in nucleus accumbens and decreasing it in the hypothalamus. |
2010-05-19 |
2023-08-12 |
rat |
| Young Sil Yoon, Taesup Cho, Sung-Hwa Yoon, Churl Ki Min, Changho Le. N-methyl amine-substituted fluoxetine derivatives: new dopamine transporter inhibitors. Archives of pharmacal research. vol 32. issue 12. 2010-05-18. PMID:20162392. |
transport of dopamine (da) by the dopamine transporter from the synaptic cleft into the presynaptic terminals plays a key role in terminating dopaminergic neurotransmission. |
2010-05-18 |
2023-08-12 |
human |
| D Nicole Riherd Methner, R Dayne Mayfiel. Ethanol alters endosomal recycling of human dopamine transporters. The Journal of biological chemistry. vol 285. issue 14. 2010-05-14. PMID:20133946. |
dynamic membrane trafficking of the monoamine dopamine transporter (dat) regulates dopaminergic signaling. |
2010-05-14 |
2023-08-12 |
human |
| Mikhail V Ugrumo. [Synthesis of monoamines by non-monoaminergic neurons: illusion or reality?]. Journal de la Societe de biologie. vol 203. issue 1. 2010-05-11. PMID:19358813. |
moreover, l-dopa captured by dopaminergic neurons and serotoninergic neurons serves to stimulate dopamine synthesis in the former and to start da synthesis in the latter. |
2010-05-11 |
2023-08-12 |
Not clear |
| Mayumi Yamato, Wataru Kudo, Takeshi Shiba, Ken-iichi Yamada, Toshiaki Watanabe, Hideo Utsum. Determination of reactive oxygen species associated with the degeneration of dopaminergic neurons during dopamine metabolism. Free radical research. vol 44. issue 3. 2010-05-11. PMID:20014978. |
determination of reactive oxygen species associated with the degeneration of dopaminergic neurons during dopamine metabolism. |
2010-05-11 |
2023-08-12 |
mouse |
| Sudarat Nimitvilai, Mark S Brodi. Reversal of prolonged dopamine inhibition of dopaminergic neurons of the ventral tegmental area. The Journal of pharmacology and experimental therapeutics. vol 333. issue 2. 2010-05-10. PMID:20164301. |
reversal of prolonged dopamine inhibition of dopaminergic neurons of the ventral tegmental area. |
2010-05-10 |
2023-08-12 |
rat |
| Marco Bisaglia, Elisa Greggio, Dragan Maric, David W Miller, Mark R Cookson, Luigi Bubacc. Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells. BMC neuroscience. vol 11. 2010-05-06. PMID:20334701. |
a plausible source of oxidative stress in nigral dopaminergic neurons is the redox reactions that specifically involve dopamine and produce various toxic molecules, i.e., free radicals and quinone species. |
2010-05-06 |
2023-08-12 |
Not clear |
| Gang Zhao, Guo-Wei Qin, Jie Wang, Wen-Jing Chu, Li-He Gu. Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt. Neurochemistry international. vol 56. issue 1. 2010-05-04. PMID:19815045. |
here, we isolated luteolin and apigenin from the fruit of perilla frutescens (l.) britt by using an activity-guided extraction technique, and proved that the two compounds possess actions of enhancing monoamine uptake either upon monoamine-transporter transgenic chinese hamster ovary (cho) cells or upon wild dopaminergic cell lines, with higher specificity for dopamine (da) uptake than for norepinephrine (ne)- and serotonin (5ht)-uptake, as well as with more potency and greater efficacy for luteolin than for apigenin. |
2010-05-04 |
2023-08-12 |
Not clear |
| Lubica Kubikova, Lubor Kostá. Dopaminergic system in birdsong learning and maintenance. Journal of chemical neuroanatomy. vol 39. issue 2. 2010-05-04. PMID:19900537. |
several song and auditory nuclei are innervated by midbrain dopaminergic fibers and contain neurons with various dopamine receptors. |
2010-05-04 |
2023-08-12 |
Not clear |
| Lubica Kubikova, Lubor Kostá. Dopaminergic system in birdsong learning and maintenance. Journal of chemical neuroanatomy. vol 39. issue 2. 2010-05-04. PMID:19900537. |
during sexually motivated singing, activity of midbrain dopaminergic neurons in the ventral tegmental area and dopamine release in the striatal area x, involved in song learning and maintenance, are higher. |
2010-05-04 |
2023-08-12 |
Not clear |
| Lubica Kubikova, Lubor Kostá. Dopaminergic system in birdsong learning and maintenance. Journal of chemical neuroanatomy. vol 39. issue 2. 2010-05-04. PMID:19900537. |
in this review we provide an overview of the dopaminergic system and neurotransmission in songbirds and the outline of possible involvement of dopamine in control of song learning, production, and maintenance. |
2010-05-04 |
2023-08-12 |
Not clear |
| Youngbin Kwak, Martijn L T M Müller, Nicolaas I Bohnen, Praveen Dayalu, Rachael D Seidle. Effect of dopaminergic medications on the time course of explicit motor sequence learning in Parkinson's disease. Journal of neurophysiology. vol 103. issue 2. 2010-05-03. PMID:20018839. |
dopaminergic medication improves dorsal and posterior striatum function by compensating for the loss of dopamine. |
2010-05-03 |
2023-08-12 |
human |
| A V Droblenkov, N P Karelina, P D Shabano. [Diagnostics of alcoholic intoxication from micromorphological changes in neurons and neuroglia of the mesoaccumbocingular dopaminergic system in experiment]. Sudebno-meditsinskaia ekspertiza. vol 52. issue 6. 2010-05-03. PMID:20088135. |
alcohol affects the mesoaccumbocingular system (ventral tegumental region, substantia nigra--nucleus accumbence--anterior cingular cortex) and other parts of the mesocorticolimbic dopaminergic system by altering patterns of dopamine release. |
2010-05-03 |
2023-08-12 |
Not clear |
| E N Rizos, S Chatziioannou, A Douzenis, N Siafakas, E Katsantoni, P Nikolaidou, M Papathanasiou, L Lykoura. Signs of striatal dopamine transporter density increase in association with improvement of tardive dyskinesia in a patient with schizophrenia, as demonstrated by a DAT scan. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 2. 2010-04-30. PMID:19740630. |
the imaging of the dopamine transporter could demonstrate the implication of dopaminergic pathway in the appearance of tardive dyskinesia. |
2010-04-30 |
2023-08-12 |
Not clear |