| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Rizelio, R E Szawka, L L Xavier, M Achaval, P Rigon, L Saur, F Matheussi, A M Delattre, J A Anselmo-Franci, M Meneses, A C Ferra. Lesion of the subthalamic nucleus reverses motor deficits but not death of nigrostriatal dopaminergic neurons in a rat 6-hydroxydopamine-lesion model of Parkinson's disease. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 43. issue 1. 2010-09-02. PMID:19967265. |
however, lesion of the stn did not prevent the reduction of striatal concentrations of dopamine and metabolites or the number of nigrostriatal dopaminergic neurons after 6-ohda lesion. |
2010-09-02 |
2023-08-12 |
rat |
| b' Sergi Ferr\\xc3\\xa. Role of the central ascending neurotransmitter systems in the psychostimulant effects of caffeine. Journal of Alzheimer\'s disease : JAD. vol 20 Suppl 1. 2010-09-02. PMID:20182056.' |
by targeting a1-a2a receptor heteromers in striatal glutamatergic terminals and a1 receptors in striatal dopaminergic terminals (presynaptic brake), caffeine induces glutamate-dependent and glutamate-independent release of dopamine. |
2010-09-02 |
2023-08-12 |
Not clear |
| Hirokuni Tagay. [Methylphenidate: pharmacology, indication and potential of abuse]. Nihon rinsho. Japanese journal of clinical medicine. vol 68. issue 8. 2010-09-02. PMID:20715493. |
methylphenidate enhances dopaminergic neurotransmission in the central nervous system by same manner with cocaine and amphetamine that bind to the dopamine transporter and inhibit dopamine uptake. |
2010-09-02 |
2023-08-12 |
Not clear |
| Shunsuke Yagi, Etsuji Yoshikawa, Masami Futatsubashi, Masamichi Yokokura, Yujiro Yoshihara, Tatsuo Torizuka, Yasuomi Ouch. Progression from unilateral to bilateral parkinsonism in early Parkinson disease: implication of mesocortical dopamine dysfunction by PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 51. issue 8. 2010-09-01. PMID:20660377. |
here, we examined in vivo changes in the brain dopaminergic system using pet with a dopamine transporter radiotracer, (11)c-2-b-carbomethoxy-3b-(4-fluorophenyl) tropane ((11)c-cft), to elucidate the pathophysiologic characteristics of the dopamine system in early converters. |
2010-09-01 |
2023-08-12 |
Not clear |
| J Best, M Reed, H F Nijhou. Models of dopaminergic and serotonergic signaling. Pharmacopsychiatry. vol 43 Suppl 1. 2010-08-25. PMID:20480448. |
mathematical models of dopaminergic and serotonergic synapses have enabled the authors to study quantitative aspects of the synthesis, release and reuptake of dopamine and serotonin, to investigate the effects of autoreceptors, and to explore the influence of the neurochemistry on the firing patterns of cells known to be involved in the behavioral responses to dopaminergic and serotonergic signaling. |
2010-08-25 |
2023-08-12 |
Not clear |
| J Best, M Reed, H F Nijhou. Models of dopaminergic and serotonergic signaling. Pharmacopsychiatry. vol 43 Suppl 1. 2010-08-25. PMID:20480448. |
three results from recent in silico experiments with the dopaminergic and serotonergic synapse models are described: (1) influence of substrate inhibition on the stability of dopamine and serotonin synthesis; (2) a predicted connection between serotonin reuptake transporter (sert) density on terminals and tonic firing rates; (3) an explanation of data from autoreceptor knock-out experiments. |
2010-08-25 |
2023-08-12 |
Not clear |
| Viktor Mózes, Melinda Bence, Mária Sasvári-Székely, Gergely Keszle. [Dopamine D4 receptor hypoxia sensitivity and child psychiatric disorders]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 12. issue 1. 2010-08-20. PMID:20305304. |
according to the prevailing view, main factors of the disorder are prefrontal dopamine deficiency and incomplete central dopaminergic functioning. |
2010-08-20 |
2023-08-12 |
Not clear |
| S D Hood, J P Potokar, S J C Davies, D A Hince, K Morris, K M Seddon, D J Nutt, S V Argyropoulo. Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants. Journal of psychopharmacology (Oxford, England). vol 24. issue 5. 2010-08-18. PMID:18838500. |
dopaminergic challenges in social anxiety disorder: evidence for dopamine d3 desensitisation following successful treatment with serotonergic antidepressants. |
2010-08-18 |
2023-08-12 |
human |
| Andrew H Evans, Andrew D Lawrence, Silke Appel Cresswell, Regina Katzenschlager, Andrew J Lee. Compulsive use of dopaminergic drug therapy in Parkinson's disease: reward and anti-reward. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 7. 2010-08-17. PMID:20461804. |
a few parkinson patients develop a disabling pattern of compulsive dopaminergic drug use ("dopamine dysregulation syndrome"-dds). |
2010-08-17 |
2023-08-12 |
Not clear |
| Gloria A Cabezas, Manuel Velasc. DA1 receptors modulation in rat isolated trachea. American journal of therapeutics. vol 17. issue 3. 2010-08-17. PMID:20496460. |
we have previously demonstrated that low dose of inhaled dopamine (0.5-2 microg kg(-1) min(-1)) induces broncodilatacion in patients with acute asthma attack, suggesting that this dopamine effect is mediated by dopaminergic rather than by adrenergic receptors. |
2010-08-17 |
2023-08-12 |
rat |
| Gloria A Cabezas, Manuel Velasc. DA1 receptors modulation in rat isolated trachea. American journal of therapeutics. vol 17. issue 3. 2010-08-17. PMID:20496460. |
to understand better these dopamine effect, rat tracheal smooth muscle was used as a model to evaluate the responses of beta2-, alpha1-, alpha2-adrenergic and da1 and da2 dopaminergic antagonists. |
2010-08-17 |
2023-08-12 |
rat |
| Gloria A Cabezas, Manuel Velasc. DA1 receptors modulation in rat isolated trachea. American journal of therapeutics. vol 17. issue 3. 2010-08-17. PMID:20496460. |
this biphasic dopaminergic response was not blocked by incubation with beta2-adrenergic antagonist propranolol (0.1 microm), alpha1-antagonist, terazosin (0.1 mm), alpha2-antagonist, yohimbine (0.1 mm), or by da2 antagonist metoclopramide (1-8 mm); da1 antagonist sch23390 (0.1 microm) produced a sustained increase of basal tone but did not block initial dopaminergic contraction and partially inhibited bronchodilator effect of dopamine. |
2010-08-17 |
2023-08-12 |
rat |
| Massimo Grilli, Laura Patti, Federica Robino, Stefania Zappettini, Maurizio Raiteri, Mario March. Release-enhancing pre-synaptic muscarinic and nicotinic receptors co-exist and interact on dopaminergic nerve endings of rat nucleus accumbens. Journal of neurochemistry. vol 105. issue 6. 2010-08-13. PMID:18298664. |
dopaminergic nerve endings in the corpus striatum possess nicotinic (nachrs) and muscarinic cholinergic receptors (machrs) mediating release of dopamine (da). |
2010-08-13 |
2023-08-12 |
rat |
| Y Aluf, J Vaya, S Khatib, Y Loboda, S Kizhner, John P M Finber. Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule. Free radical research. vol 44. issue 6. 2010-08-13. PMID:20370558. |
partial dopaminergic deafferentation was induced by injection of 6-hydroxydopamine (250 microg) to the left lateral ventricle, which depleted ipsilateral striatal dopamine by 46% and dopaminergic cells in left substantia nigra by 44%, 5 weeks after administration. |
2010-08-13 |
2023-08-12 |
rat |
| Heleen A Slagter, Richard J Davidson, Rachel Tome. Eye-blink rate predicts individual differences in pseudoneglect. Neuropsychologia. vol 48. issue 5. 2010-08-09. PMID:20036680. |
this finding may support the idea that the observed attentional bias in healthy individuals reflects asymmetries in dopaminergic circuits, and corroborates previous findings implicating dopamine in spatial attention. |
2010-08-09 |
2023-08-12 |
Not clear |
| Joseph P Gabriele, Giuseppe F Pontoriero, Nancy Thomas, Mark A Ferro, Geetha Mahadevan, Duncan J MacCrimmon, Zdenek B Pristupa, Ram K Mishr. Antipsychotic drug use is correlated with CRP40/mortalin mRNA expression in the dorsolateral prefrontal cortex of human postmortem brain specimens. Schizophrenia research. vol 119. issue 1-3. 2010-07-30. PMID:20100649. |
crp40 shares an intimate association with dopaminergic activity, specifically as it pertains to dopamine dysregulation in schizophrenia. |
2010-07-30 |
2023-08-12 |
human |
| Dean E Dluzen, Jing Ji, Janet L McDermot. Age-related changes in nigrostriatal dopaminergic function in heterozygous mutant dopamine transporter knock-out mice. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20382201. |
age-related changes in nigrostriatal dopaminergic function in heterozygous mutant dopamine transporter knock-out mice. |
2010-07-30 |
2023-08-12 |
mouse |
| Dean E Dluzen, Jing Ji, Janet L McDermot. Age-related changes in nigrostriatal dopaminergic function in heterozygous mutant dopamine transporter knock-out mice. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20382201. |
in this report we compared three different parameters of nigrostriatal dopaminergic (nsda) function - locomotor activity, striatal dopamine (da) levels and 3,4-dihydroxyphenylacetic acid (dopac)/da ratios between heterozygous mutant dopamine transporter mice (+/- dat) and their wild type controls (+/+ dat) at three different age range periods: 4-10, 11-17 and 18-24 months of age. |
2010-07-30 |
2023-08-12 |
mouse |
| Adrian P Kells, Jamie Eberling, Xiaomin Su, Philip Pivirotto, John Bringas, Piotr Hadaczek, Wade C Narrow, William J Bowers, Howard J Federoff, John Forsayeth, Krystof S Bankiewic. Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 28. 2010-07-30. PMID:20631185. |
the observed progressive amelioration of functional deficits, recovery of dopamine, and regrowth of fibers to the striatal neuropil demonstrate that high gdnf expression in the putamen promotes restoration of the dopaminergic system in a primate model of advanced pd. |
2010-07-30 |
2023-08-12 |
Not clear |
| F Campos, M Alfonso, R Durá. In vivo modulation of alpha7 nicotinic receptors on striatal glutamate release induced by anatoxin-A. Neurochemistry international. vol 56. issue 6-7. 2010-07-29. PMID:20347906. |
in vitro studies suggest that alpha7 nicotinic receptors located on striatal glutamatergic terminals stimulate the release of glutamate which in turn acts at ionotropic glutamate receptors on dopaminergic terminals to increase dopamine release. |
2010-07-29 |
2023-08-12 |
Not clear |