| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sung Yul Kim, Hyo Jin Lee, Yong Nyun Kim, Sehyoun Yoon, Jong Eun Lee, Woong Sun, Eui-Ju Choi, Ja-Hyun Bai. Striatal-enriched protein tyrosine phosphatase regulates dopaminergic neuronal development via extracellular signal-regulated kinase signaling. Experimental neurology. vol 214. issue 1. 2010-07-21. PMID:18708052. |
we have previously shown that signaling through dopamine d2 receptor (d2r)-mediated extracellular signal-regulated kinase (erk) activation plays a critical role in mesencephalic dopaminergic neuronal development. |
2010-07-21 |
2023-08-12 |
mouse |
| Sung Yul Kim, Hyo Jin Lee, Yong Nyun Kim, Sehyoun Yoon, Jong Eun Lee, Woong Sun, Eui-Ju Choi, Ja-Hyun Bai. Striatal-enriched protein tyrosine phosphatase regulates dopaminergic neuronal development via extracellular signal-regulated kinase signaling. Experimental neurology. vol 214. issue 1. 2010-07-21. PMID:18708052. |
these results suggest that step is an important mediator in the dopamine d2r-mediated activation of erk signaling and in the regulation of dopaminergic neuronal development. |
2010-07-21 |
2023-08-12 |
mouse |
| Fabrizio Stocch. The concept of continuous dopaminergic stimulation: what we should consider when starting Parkinson's disease treatment. Neuro-degenerative diseases. vol 7. issue 1-3. 2010-07-21. PMID:20224289. |
dopamine (da) agonists delay motor fluctuations in humans providing a more continuous dopaminergic stimulation. |
2010-07-21 |
2023-08-12 |
Not clear |
| Sharon R Grady, Ryan M Drenan, Scott R Breining, Daniel Yohannes, Charles R Wageman, Nikolai B Fedorov, Sheri McKinney, Paul Whiteaker, Merouane Bencherif, Henry A Lester, Michael J Mark. Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20114055. |
both subtypes modulate release of dopamine from the dopaminergic neurons of the mesoaccumbens pathway thought to be essential for reward and addiction. |
2010-07-19 |
2023-08-12 |
mouse |
| Yu-Hua Tian, Joung-Hee Baek, Seok-Yong Lee, Choon-Gon Jan. Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice. Synapse (New York, N.Y.). vol 64. issue 6. 2010-07-19. PMID:20169576. |
finally, to measure changes in the dopaminergic and nmdaergic systems in the brain, we performed autoradiographic receptor binding assays for dopamine d(1) and d(2) receptors, the nmda receptor, and the dopamine transporter. |
2010-07-19 |
2023-08-12 |
mouse |
| Simon Cervenka, Andrea Varrone, Erik Fransén, Christer Halldin, Lars Fard. PET studies of D2-receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans. Synapse (New York, N.Y.). vol 64. issue 6. 2010-07-19. PMID:20175222. |
most molecular imaging studies of the dopamine (da) system performed to date have focused on the striatum, a region receiving dense dopaminergic innervation. |
2010-07-19 |
2023-08-12 |
human |
| Antonio C Farias, Alexandre Cunha, Cássia R Benko, James T McCracken, Maria T Costa, Lucilene G Farias, Mara L Cordeir. Manganese in children with attention-deficit/hyperactivity disorder: relationship with methylphenidate exposure. Journal of child and adolescent psychopharmacology. vol 20. issue 2. 2010-07-15. PMID:20415606. |
recent studies have suggested that mn accumulates in dopaminergic neurons via the presynaptic dopamine transporter (dat). |
2010-07-15 |
2023-08-12 |
Not clear |
| M S Nandhu, E T Fabia, C S Paulos. Dopamine D1 receptor gene expression studies in unilateral 6-hydroxydopamine-lesioned Parkinson's rat: effect of 5-HT, GABA, and bone marrow cell supplementation. Journal of molecular neuroscience : MN. vol 41. issue 1. 2010-07-12. PMID:19578995. |
many potential compensatory mechanisms have now been proposed; these are both dopaminergic, focused on enhancing effects or exposure to existing dopamine, and non-dopaminergic, being focused on reducing activity of the indirect striatal output pathway. |
2010-07-12 |
2023-08-12 |
rat |
| M S Nandhu, E T Fabia, C S Paulos. Dopamine D1 receptor gene expression studies in unilateral 6-hydroxydopamine-lesioned Parkinson's rat: effect of 5-HT, GABA, and bone marrow cell supplementation. Journal of molecular neuroscience : MN. vol 41. issue 1. 2010-07-12. PMID:19578995. |
dopaminergic binding parameters were done by scatchard analysis of dopamine d(1) receptor-binding assay using [(3)h]sch 23390. |
2010-07-12 |
2023-08-12 |
rat |
| Béchir Jarraya, Sabrina Boulet, G Scott Ralph, Caroline Jan, Gilles Bonvento, Mimoun Azzouz, James E Miskin, Masahiro Shin, Thierry Delzescaux, Xavier Drouot, Anne-Sophie Hérard, Denise M Day, Emmanuel Brouillet, Susan M Kingsman, Philippe Hantraye, Kyriacos A Mitrophanous, Nicholas D Mazarakis, Stéphane Palf. Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia. Science translational medicine. vol 1. issue 2. 2010-07-12. PMID:20368163. |
the standard treatment is administration of pharmacological agents that transiently increase concentrations of brain dopamine and thereby discontinuously modulate neuronal activity in the striatum, the primary target of dopaminergic neurons. |
2010-07-12 |
2023-08-12 |
monkey |
| Stéphanie Vuillermot, Liz Weber, Joram Feldon, Urs Meye. A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 4. 2010-07-08. PMID:20107055. |
prenatal immune activation thus appears to be a significant environmental risk factor for primary defects in normal dopaminergic development and facilitates the expression of postnatal dopamine dysfunctions involved in the precipitation of psychosis-related behavior. |
2010-07-08 |
2023-08-12 |
mouse |
| M Garcia-Garcia, F Barceló, I C Clemente, C Escer. The role of the dopamine transporter DAT1 genotype on the neural correlates of cognitive flexibility. The European journal of neuroscience. vol 31. issue 4. 2010-07-08. PMID:20141527. |
neuropharmacological and human clinical studies have suggested a critical role for striatal dopaminergic function mediated by the dopamine transporter (dat). |
2010-07-08 |
2023-08-12 |
human |
| R G Averkin, V A Korshunov, N V Shchegolevskiĭ, V N Mats, V A Markevich, G A Grigor'ian, A S Bazia. [Study of extracellular concentration of dopamine and its metabolites in mice striatum by a microdialysis technique at intraperitoneal administration of MPTP]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 60. issue 1. 2010-07-06. PMID:20352690. |
there was suggested that a reduction of the dopamine concentration immediately after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine injection connected with abnormalities of dopamine synthesis and metabolism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine whereas a reduction of the extracellular striatal dopamine concentration 30 days after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration related to damage of the nigrastriatal dopaminergic system. |
2010-07-06 |
2023-08-12 |
mouse |
| Christina E Khodr, Sara Clark, Alex F Bokov, Arlan Richardson, Randy Strong, David L Hurley, Carol J Phelp. Early postnatal administration of growth hormone increases tuberoinfundibular dopaminergic neuron numbers in Ames dwarf mice. Endocrinology. vol 151. issue 7. 2010-07-05. PMID:20463054. |
hypothalamic tuberoinfundibular dopaminergic (tida) neurons secrete dopamine, which inhibits pituitary prolactin (prl) secretion. |
2010-07-05 |
2023-08-12 |
mouse |
| Garret D Stuber, Thomas S Hnasko, Jonathan P Britt, Robert H Edwards, Antonello Bonc. Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554874. |
here, we expressed the light-activated cation channel channelrhodopsin-2 (chr2) in genetically defined midbrain dopamine neurons to stimulate exocytosis specifically from dopaminergic terminals in both the nucleus accumbens (nac) shell and dorsal striatum of brain slices from adult mice. |
2010-07-02 |
2023-08-12 |
mouse |
| Riccardo Viaro, Matteo Marti, Michele Morar. Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade. Experimental neurology. vol 223. issue 2. 2010-07-01. PMID:20122926. |
this impairment was associated with approximately 60% loss of striatal dopamine terminals, as revealed by tyrosine hydroxylase immunohistochemistry, and was attenuated by dopaminergic drugs. |
2010-07-01 |
2023-08-12 |
mouse |
| Chen Zhang, Yiru Fang, Bin Xie, Wenhong Cheng, Yasong Du, Dongxiang Wang, Shunying Y. No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia. Psychiatry research. vol 177. issue 3. 2010-07-01. PMID:20382433. |
the dopamine d1 receptor (drd1) plays an important role in mediating dopaminergic transmission in the pfc. |
2010-07-01 |
2023-08-12 |
human |
| Young-Min Shon, Kendall H Lee, Stephan J Goerss, In Yong Kim, Chris Kimble, Jamie J Van Gompel, Kevin Bennet, Charles D Blaha, Su-Youne Chan. High frequency stimulation of the subthalamic nucleus evokes striatal dopamine release in a large animal model of human DBS neurosurgery. Neuroscience letters. vol 475. issue 3. 2010-06-30. PMID:20347936. |
taken together, these results support a dopamine neuronal activation hypothesis suggesting that stn dbs evokes striatal dopamine release by stimulation of nigrostriatal dopaminergic neurons. |
2010-06-30 |
2023-08-12 |
human |
| Youren Tong, Hiroo Yamaguchi, Emilie Giaime, Scott Boyle, Raphael Kopan, Raymond J Kelleher, Jie She. Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 21. 2010-06-29. PMID:20457918. |
the dopaminergic system of lrrk2(-/-) mice appears normal, and numbers of dopaminergic neurons and levels of striatal dopamine are unchanged. |
2010-06-29 |
2023-08-12 |
mouse |
| Abdelmojib Al-Wandi, Natalia Ninkina, Steven Millership, Sally J M Williamson, Paul A Jones, Vladimir L Buchma. Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice. Neurobiology of aging. vol 31. issue 5. 2010-06-28. PMID:19097673. |
in particular, no significant changes in striatal dopamine metabolism and only subtle deficit of dopaminergic neurons in the substantia nigra were found in juvenile or adult mice. |
2010-06-28 |
2023-08-12 |
mouse |