| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antoine R Adamantidis, Hsing-Chen Tsai, Benjamin Boutrel, Feng Zhang, Garret D Stuber, Evgeny A Budygin, Clara Touriño, Antonello Bonci, Karl Deisseroth, Luis de Lece. Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 30. 2011-10-07. PMID:21795535. |
in this study, we first targeted the expression of channelrhodopsin-2 to dopaminergic neurons of the vta and optimized optogenetically evoked dopamine transients. |
2011-10-07 |
2023-08-12 |
mouse |
| Ai-Jun Zhang, Roy Jacoby, Samuel M W. Light- and dopamine-regulated receptive field plasticity in primate horizontal cells. The Journal of comparative neurology. vol 519. issue 11. 2011-10-06. PMID:21452210. |
because light elevates dopamine release in primate retina, our results support a dopaminergic role in post-receptoral light adaptation by decreasing hc receptive field diameters, which influences the center-surround receptive field organization of higher-order neurons and thereby spatial contrast sensitivity. |
2011-10-06 |
2023-08-12 |
monkey |
| Fabiana da Silva Alves, Nicole Schmitz, Martijn Figee, Nico Abeling, Gregor Hasler, Johan van der Meer, Aart Nederveen, Lieuwe de Haan, Don Linszen, Therese van Amelsvoor. Dopaminergic modulation of the human reward system: a placebo-controlled dopamine depletion fMRI study. Journal of psychopharmacology (Oxford, England). vol 25. issue 4. 2011-10-05. PMID:20530591. |
dopaminergic modulation of the human reward system: a placebo-controlled dopamine depletion fmri study. |
2011-10-05 |
2023-08-12 |
human |
| Fabiana da Silva Alves, Nicole Schmitz, Martijn Figee, Nico Abeling, Gregor Hasler, Johan van der Meer, Aart Nederveen, Lieuwe de Haan, Don Linszen, Therese van Amelsvoor. Dopaminergic modulation of the human reward system: a placebo-controlled dopamine depletion fMRI study. Journal of psychopharmacology (Oxford, England). vol 25. issue 4. 2011-10-05. PMID:20530591. |
in addition to blood-oxygen-level-dependent (bold) contrast we assessed the effect of dopaminergic depletion on prolactin response, peripheral markers for dopamine and norepinephrine. |
2011-10-05 |
2023-08-12 |
human |
| Fabiana da Silva Alves, Nicole Schmitz, Martijn Figee, Nico Abeling, Gregor Hasler, Johan van der Meer, Aart Nederveen, Lieuwe de Haan, Don Linszen, Therese van Amelsvoor. Dopaminergic modulation of the human reward system: a placebo-controlled dopamine depletion fMRI study. Journal of psychopharmacology (Oxford, England). vol 25. issue 4. 2011-10-05. PMID:20530591. |
our findings implicate distinct patterns of bold underlying reward processing following dopamine depletion, suggesting a role of dopaminergic neurotransmission for anticipation of monetary reward. |
2011-10-05 |
2023-08-12 |
human |
| Angelo Antonini, Giulia Ursino, Daniela Calandrella, Laura Bernardi, Mauro Pleban. Continuous dopaminergic delivery in Parkinson's disease. Journal of neurology. vol 257. issue Suppl 2. 2011-10-03. PMID:21080194. |
all studies comparing levodopa versus dopamine agonist early therapy indicate that initiation with agonists is associated with a reduced risk of motor complications -in particular, dyskinesias- possibly because agonists' longer half-lives provide continuous dopaminergic delivery. |
2011-10-03 |
2023-08-12 |
Not clear |
| Pia Jensen, Jan-Bert Gramsbergen, Jens Zimmer, Hans R Widmer, Morten Meye. Enhanced proliferation and dopaminergic differentiation of ventral mesencephalic precursor cells by synergistic effect of FGF2 and reduced oxygen tension. Experimental cell research. vol 317. issue 12. 2011-10-03. PMID:21570391. |
low oxygen during fgf2-mediated expansion resulted also in a significant increase in tyrosine hydroxylase-immunoreactive (th-ir) dopaminergic neurons as compared to high oxygen tension, but no corresponding effect was observed for dopamine release into the culture medium. |
2011-10-03 |
2023-08-12 |
rat |
| Toshihiko Iwanaga, Yasukazu Hozumi, Hiromi Takahashi-Iwanag. Immunohistochemical demonstration of dopamine receptor D2R in the primary cilia of the mouse pituitary gland. Biomedical research (Tokyo, Japan). vol 32. issue 3. 2011-10-03. PMID:21673453. |
since there is accumulating evidence that the primary cilium functions as a sensory device at a cellular level, the d2r-expressing primary cilia in the pituitary gland may be involved in the sensation of dopamine and dopaminergic compounds-though their involvement differs between the anterior and intermediate lobes. |
2011-10-03 |
2023-08-12 |
mouse |
| Olivier Rascol, Andres Lozano, Matthew Stern, Werner Poew. Milestones in Parkinson's disease therapeutics. Movement disorders : official journal of the Movement Disorder Society. vol 26. issue 6. 2011-09-30. PMID:21626552. |
novel dopamine agonists (pramipexole, ropinirole, rotigotine), catecholmethyltransferase inhibitors (entacapone), and monoamine oxidase b inhibitors (rasagiline) have also been developed to provide more continuous oral delivery of dopaminergic stimulation in order to improve motor outcomes. |
2011-09-30 |
2023-08-12 |
Not clear |
| Yinglan Zhao, Qian Bu, Yan Zhou, Lei Lv, Guangyan Yan, Bo Chen, Li Wang, Xiaobo Ce. Mechanism study of Aconitum-induced neurotoxicity in PC12 cells: involvement of dopamine release and oxidative damage. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20600291. |
in conclusion, our results indicate that aconitum can evoke dopamine release from dopaminergic neurons; excessive extracellular of dopamine can then create stresses on cellular antioxidant systems and induce neuron apoptosis. |
2011-09-29 |
2023-08-12 |
mouse |
| Ulrich Pfisterer, Agnete Kirkeby, Olof Torper, James Wood, Jenny Nelander, Audrey Dufour, Anders Björklund, Olle Lindvall, Johan Jakobsson, Malin Parma. Direct conversion of human fibroblasts to dopaminergic neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 25. 2011-09-29. PMID:21646515. |
by combining expression of the three conversion factors with expression of two genes involved in dopamine neuron generation, lmx1a and foxa2, we could direct the phenotype of the converted cells toward dopaminergic neurons. |
2011-09-29 |
2023-08-12 |
mouse |
| Shakila Abdul-Majeed, Surya M Naul. Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles. Hypertension (Dallas, Tex. : 1979). vol 58. issue 2. 2011-09-28. PMID:21709211. |
to determine the roles of the dopaminergic system and mechano-sensory cilia, we studied the effects of dopamine on ciliary length and function in wild-type and mechano-insensitive polycystic mutant cells (pkd1(-/)(-) and tg737(orpk/orpk)). |
2011-09-28 |
2023-08-12 |
mouse |
| Sarah J Kotowski, F Woodward Hopf, Taban Seif, Antonello Bonci, Mark von Zastro. Endocytosis promotes rapid dopaminergic signaling. Neuron. vol 71. issue 2. 2011-09-23. PMID:21791287. |
d(1) dopamine receptors are primary mediators of dopaminergic signaling in the cns. |
2011-09-23 |
2023-08-12 |
Not clear |
| Simona Scheggi, Giovanna Marchese, Silvia Grappi, Maria Elena Secci, Maria Graziella De Montis, Carla Gambaran. Cocaine sensitization models an anhedonia-like condition in rats. The international journal of neuropsychopharmacology. vol 14. issue 3. 2011-09-19. PMID:20519061. |
this dopaminergic response is associated with consistent modifications in the phosphorylation pattern of some camp-dependent protein kinase (pka) substrates and it is mediated by dopamine d1 receptor stimulation. |
2011-09-19 |
2023-08-12 |
rat |
| Simona Scheggi, Giovanna Marchese, Silvia Grappi, Maria Elena Secci, Maria Graziella De Montis, Carla Gambaran. Cocaine sensitization models an anhedonia-like condition in rats. The international journal of neuropsychopharmacology. vol 14. issue 3. 2011-09-19. PMID:20519061. |
indeed, non-food-deprived cocaine-sensitized rats showed no interest in palatable food, no dopaminergic response after a palatable meal in terms of increased dopamine output and darpp-32 phosphorylation changes, and no ability to acquire a palatable food-sustained instrumental behaviour. |
2011-09-19 |
2023-08-12 |
rat |
| Bastian Zimmer, Stefan Schildknecht, Philipp B Kuegler, Vivek Tanavde, Suzanne Kadereit, Marcel Leis. Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21385734. |
the mixed neuronal cultures that formed within 20 days contained a small subpopulation of tyrosine hydroxylase (th)-positive neurons with specific dopaminergic functions such as dopamine transport (dat) activity. |
2011-09-19 |
2023-08-12 |
Not clear |
| Maria L Cucchiaroni, Peter S Freestone, Nicola Berretta, Maria T Viscomi, Elisa Bisicchia, Hideyuki Okano, Marco Molinari, Giorgio Bernardi, Janusz Lipski, Nicola B Mercuri, Ezia Guatte. Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21453288. |
properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. |
2011-09-16 |
2023-08-12 |
mouse |
| Maria L Cucchiaroni, Peter S Freestone, Nicola Berretta, Maria T Viscomi, Elisa Bisicchia, Hideyuki Okano, Marco Molinari, Giorgio Bernardi, Janusz Lipski, Nicola B Mercuri, Ezia Guatte. Properties of dopaminergic neurons in organotypic mesencephalic-striatal co-cultures--evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α-1 adrenergic receptors. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21453288. |
immunocytochemistry revealed that many synaptic terminals, most likely originating from dopaminergic neurons, co-expressed the dopamine (da) transporter and the vesicular glutamate transporter-2, suggesting a co-release of da and glutamate. |
2011-09-16 |
2023-08-12 |
mouse |
| Chantal Martin-Soelch, Joanna Szczepanik, Allison Nugent, Krystle Barhaghi, Denise Rallis, Peter Herscovitch, Richard E Carson, Wayne C Drevet. Lateralization and gender differences in the dopaminergic response to unpredictable reward in the human ventral striatum. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21453423. |
with respect to other functions of the mesostriatal dopaminergic system, dopamine's actions show prominent laterality effects. |
2011-09-16 |
2023-08-12 |
human |
| Massimiliano Caiazzo, Maria Teresa Dell'Anno, Elena Dvoretskova, Dejan Lazarevic, Stefano Taverna, Damiana Leo, Tatyana D Sotnikova, Andrea Menegon, Paola Roncaglia, Giorgia Colciago, Giovanni Russo, Piero Carninci, Gianni Pezzoli, Raul R Gainetdinov, Stefano Gustincich, Alexander Dityatev, Vania Broccol. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature. vol 476. issue 7359. 2011-09-16. PMID:21725324. |
in particular, transplantation of embryonic-stem-cell-derived dopaminergic neurons has been shown to be efficient in restoring motor symptoms in conditions of dopamine deficiency. |
2011-09-16 |
2023-08-12 |
mouse |