| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maryka Quik, Xiomara A Perez, Sharon R Grad. Role of α6 nicotinic receptors in CNS dopaminergic function: relevance to addiction and neurological disorders. Biochemical pharmacology. vol 82. issue 8. 2011-10-21. PMID:21684266. |
they appear to have a dominant role in regulating dopamine release, with consequent effects on nachr-modulated dopaminergic functions such as reinforcement and motor behavior. |
2011-10-21 |
2023-08-12 |
Not clear |
| Neivo da Silva, Claudia M Szobot, Carlos E Anselmi, Andrea P Jackowski, Shih M Chi, Marcelo Q Hoexter, Osvaldo E Anselmi, Flavio Pechansky, Rodrigo A Bressan, Luis A Rohd. Attention deficit/hyperactivity disorder: is there a correlation between dopamine transporter density and cerebral blood flow? Clinical nuclear medicine. vol 36. issue 8. 2011-10-21. PMID:21716015. |
although the etiology remains unclear, the involvement of the dopaminergic system has been suggested by genetic studies that report an overexpression of the dopamine transporter (dat) gene. |
2011-10-21 |
2023-08-12 |
Not clear |
| Daniela Calandrella, Angelo Antonin. Pathological gambling in Parkinson's disease: disease related or drug related? Expert review of neurotherapeutics. vol 11. issue 6. 2011-10-20. PMID:21651329. |
pathological gambling and other impulse-control disorders occur in susceptible parkinson's disease patients during dopaminergic therapy, particularly in association with dopamine agonists. |
2011-10-20 |
2023-08-12 |
Not clear |
| Sean C Dyson, Roger A Barke. Cell-based therapies for Parkinson's disease. Expert review of neurotherapeutics. vol 11. issue 6. 2011-10-20. PMID:21651331. |
neurodegeneration in pd critically involves the dopaminergic neurons of the substantia nigra pars compacta, which results in a severe reduction in dopamine levels in the dorsal striatum. |
2011-10-20 |
2023-08-12 |
Not clear |
| Morten Ziebel. Evaluation of the superselective radioligand [123I]PE2I for imaging of the dopamine transporter in SPECT. Danish medical bulletin. vol 58. issue 5. 2011-10-19. PMID:21535991. |
imaging of the dopamine transporter (dat) with single photon emission computer tomography (spect) has increasingly been used as a biomarker for the integrity of presynaptic dopaminergic nerve cells in patients with movement disorders. |
2011-10-19 |
2023-08-12 |
human |
| Stefano Espinoza, Ali Salahpour, Bernard Masri, Tatyana D Sotnikova, Mirko Messa, Larry S Barak, Marc G Caron, Raul R Gainetdino. Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor. Molecular pharmacology. vol 80. issue 3. 2011-10-18. PMID:21670104. |
in particular, there is evidence suggesting that the trace amine-associated receptor 1 (taar1) affects the dopaminergic system by regulating the firing rate of dopaminergic neurons or by altering dopamine d2 receptor (d2r) responsiveness to ligands. |
2011-10-18 |
2023-08-12 |
mouse |
| Damian Refojo, Martin Schweizer, Claudia Kuehne, Stefanie Ehrenberg, Christoph Thoeringer, Annette M Vogl, Nina Dedic, Marion Schumacher, Gregor von Wolff, Charilaos Avrabos, Chadi Touma, David Engblom, Günther Schütz, Klaus-Armin Nave, Matthias Eder, Carsten T Wotjak, Inge Sillaber, Florian Holsboer, Wolfgang Wurst, Jan M Deussin. Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science (New York, N.Y.). vol 333. issue 6051. 2011-10-18. PMID:21885734. |
selective deletion of crhr1 in midbrain dopaminergic neurons increases anxiety-like behavior and reduces dopamine release in the prefrontal cortex. |
2011-10-18 |
2023-08-12 |
Not clear |
| A V Kholodar', A V Amikishieva, M P Anisimo. [Effect of intranasal administration of dopamine on anxiety and locomotor activity of two lines of mice]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 97. issue 7. 2011-10-18. PMID:21961293. |
dopamine was introduced as nose drops or inhalation of nanoparticles of the compound solution in c57b1/6j and cba/lac mice with differences of dopaminergic function features. |
2011-10-18 |
2023-08-12 |
mouse |
| Jyoti C Patel, Paul Witkovsky, William A Coetzee, Margaret E Ric. Subsecond regulation of striatal dopamine release by pre-synaptic KATP channels. Journal of neurochemistry. vol 118. issue 5. 2011-10-14. PMID:21689107. |
consistent with the presence of functional k(atp) channels on dopaminergic axons, k(atp)-channel openers, diazoxide and cromakalim, suppressed single-pulse evoked dopamine release. |
2011-10-14 |
2023-08-12 |
Not clear |
| Jyoti C Patel, Paul Witkovsky, William A Coetzee, Margaret E Ric. Subsecond regulation of striatal dopamine release by pre-synaptic KATP channels. Journal of neurochemistry. vol 118. issue 5. 2011-10-14. PMID:21689107. |
together, these studies reveal subsecond regulation of striatal dopamine release by endogenous h(2)o(2) acting at k(atp) channels on dopaminergic axons, including a role in paired-pulse suppression. |
2011-10-14 |
2023-08-12 |
Not clear |
| E A Aristakesia. [Effect of apomorphine on the wakefulness--sleep cycle of the common frog Rana temporaria]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 47. issue 4. 2011-10-14. PMID:21938912. |
taking into account that the states of catalepsy and cataplexy in frogs are under control of the anterior hypothalamus, it can be suggested that manifestations of cataplexy (sleep) in frog are due to the low level of dopaminergic activity, whereas manifestations of catalepsy (the homologue of stress reaction) are due to the high dopamine content in the anterioi hypothalamic structures. |
2011-10-14 |
2023-08-12 |
Not clear |
| E A Aristakesia. [Effect of apomorphine on the wakefulness--sleep cycle of the common frog Rana temporaria]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 47. issue 4. 2011-10-14. PMID:21938912. |
comparative analysis of changes in wsc of amphibians and mammals in response to administration of dopamine and its agonists allows thinking that the role of the dopaminergic neurotransmitter system in regulation of the vertebrate wsc is unanimous: the low level of activity of this system facilitates development of sleep (catalepsy), whereas the high level provides reaction of arousal and is actively included in the system providing stress-reaction. |
2011-10-14 |
2023-08-12 |
Not clear |
| Sa Suk Kim, Kyung Rok Moon, Hyun Jin Cho. Interference of alpha-synuclein with cAMP/PKA-dependent CREB signaling for tyrosine hydroxylase gene expression in SK-N-BE(2)C cells. Archives of pharmacal research. vol 34. issue 5. 2011-10-13. PMID:21656370. |
early studies have demonstrated that interaction of α-syn and tyrosine hydroxylase (th), a rate-limiting enzyme in dopamine synthesis, is functionally significant for dopaminergic neurotransmission and the pathophysiology of parkinson's disease. |
2011-10-13 |
2023-08-12 |
Not clear |
| Alex Iranzo, Francesc Valldeoriola, Francisco Lomeña, José Luis Molinuevo, Mónica Serradell, Manel Salamero, Albert Cot, Domènec Ros, Javier Pavía, Joan Santamaria, Eduardo Tolos. Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study. The Lancet. Neurology. vol 10. issue 9. 2011-10-13. PMID:21802993. |
serial dopamine transporter (dat) imaging in patients with parkinson's disease (pd) and other synucleinopathies shows progressive nigrostriatal dopaminergic dysfunction. |
2011-10-13 |
2023-08-12 |
Not clear |
| C V Fontanilla, Z Ma, X Wei, J Klotsche, L Zhao, P Wisniowski, R C Dodel, M R Farlow, W H Oertel, Y D. Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration. Neuroscience. vol 188. 2011-10-12. PMID:21571045. |
parkinson's disease is associated with the loss of dopaminergic neurons in the substantia nigra and decreased striatal dopamine levels. |
2011-10-12 |
2023-08-12 |
mouse |
| C V Fontanilla, Z Ma, X Wei, J Klotsche, L Zhao, P Wisniowski, R C Dodel, M R Farlow, W H Oertel, Y D. Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration. Neuroscience. vol 188. 2011-10-12. PMID:21571045. |
we now report that caffeic acid phenethyl ester (cape), an active component of propolis, attenuated dopaminergic neurodegeneration and dopamine loss in the mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of parkinson's disease. |
2011-10-12 |
2023-08-12 |
mouse |
| K B Reynolds, L MacGillivray, M Zettler, P I Rosebush, M F Mazure. Role of the dopamine transporter in mediating the neuroleptic-induced reduction of tyrosine hydroxylase-immunoreactive midbrain neurons. Brain research. vol 1394. 2011-10-11. PMID:21396352. |
these results indicate a role for the active dopamine transporter in mediating the suppression of th expression in midbrain dopaminergic neurons by antipsychotic drugs. |
2011-10-11 |
2023-08-12 |
rat |
| Alessandra Lintas, Ning Chi, Nicole M Lauzon, Stephanie F Bishop, Shervin Gholizadeh, Ninglei Sun, Huibing Tan, Steven R Laviolett. Identification of a dopamine receptor-mediated opiate reward memory switch in the basolateral amygdala-nucleus accumbens circuit. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 31. 2011-10-11. PMID:21813678. |
the bla receives innervation from dopaminergic fibers originating in the vta, and both dopamine (da) d1 and d2 receptors are expressed in this region. |
2011-10-11 |
2023-08-12 |
rat |
| Jes Paul, Korah P Kuruvilla, Jobin Mathew, Peeyush Kumar, C S Paulos. Dopamine D₁ and D₂ receptor subtypes functional regulation in cerebral cortex of unilateral rotenone lesioned Parkinson's rat model: Effect of serotonin, dopamine and norepinephrine. Parkinsonism & related disorders. vol 17. issue 4. 2011-10-10. PMID:21306935. |
parkinson's disease is a progressive neurodegenerative disorder characterized by selective degeneration of dopaminergic neurons in substantia nigra pars compacta leading to marked reduction of dopamine levels in the cerebral cortex. |
2011-10-10 |
2023-08-12 |
rat |
| Barbara Pavan, Guglielmo Paganetto, Alessandro Dalpia. Dopamine-sensitive adenylyl cyclases in neuronal development: physiopathological and pharmacological implications. Drug discovery today. vol 16. issue 11-12. 2011-10-07. PMID:21477663. |
here, we discuss dopamine (da)-sensitive isoforms of ac as key cues for dopaminergic neuronal patterning and as interesting therapeutic targets for the induction of regenerative processes or to drive correct neuronal development. |
2011-10-07 |
2023-08-12 |
Not clear |