| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ashutosh Kumar, Brajesh Kumar Singh, Israr Ahmad, Smriti Shukla, Devendra Kumar Patel, Garima Srivastava, Vinod Kumar, Haushila Prasad Pandey, Chetna Sing. Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: similarity with paraquat neurotoxicity. Brain research. vol 1438. 2012-07-17. PMID:22244881. |
apocynin and/or nac pre-treatment significantly alleviated zn- and pq-induced changes in neurobehavioral deficits, number of dopaminergic neurons and contents of the striatal dopamine and its metabolites. |
2012-07-17 |
2023-08-12 |
rat |
| Raymond C Harris, Ming-Zhi Zhan. Dopamine, the kidney, and hypertension. Current hypertension reports. vol 14. issue 2. 2012-07-16. PMID:22407378. |
there is increasing evidence that the intrarenal dopaminergic system plays an important role in the regulation of blood pressure, and defects in dopamine signaling appear to be involved in the development of hypertension. |
2012-07-16 |
2023-08-12 |
human |
| François J G Vingerhoets, Pierre R Burkhar. [Resistance to treatment in movement disorders]. Revue medicale suisse. vol 8. issue 339. 2012-07-10. PMID:22675821. |
when pd becomes resistant to dopamine replacement therapy using various combinations of dopaminergic agents, then three options can be discussed: first, a subcutaneous apomorphine mini-pump, second, a jejunal levodopa-delivery system by means of percutaneous gastrostomy, and third, bilateral deep brain stimulation of the subthalamic nucleus. |
2012-07-10 |
2023-08-12 |
Not clear |
| Miguel Schwartz, Sergiu Sabeta. An approach to the continuous dopaminergic stimulation in Parkinson's disease. The Israel Medical Association journal : IMAJ. vol 14. issue 3. 2012-07-10. PMID:22675859. |
dopaminergic neurons in the basal ganglia normally fire in a continuous manner, maintaining the striatal dopamine concentration at a relatively constant level. |
2012-07-10 |
2023-08-12 |
Not clear |
| Anja Drinkut, Yuliya Tereshchenko, Jörg B Schulz, Mathias Bähr, Sebastian Kügle. Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery. Molecular therapy : the journal of the American Society of Gene Therapy. vol 20. issue 3. 2012-07-09. PMID:22086235. |
in terms of protection of dopaminergic cell bodies and projections, dopamine (da) synthesis and behaviour, astrocyte-derived gdnf demonstrated the same efficacy as neuron-derived gdnf. |
2012-07-09 |
2023-08-12 |
mouse |
| R Al-Hasani, J D Foster, A Metaxas, C Ledent, S M O Hourani, I Kitchen, Y Che. Increased desensitization of dopamine D₂ receptor-mediated response in the ventral tegmental area in the absence of adenosine A(2A) receptors. Neuroscience. vol 190. 2012-07-05. PMID:21669258. |
the a(2a) receptor agonist, cgs21680, did not exert any effect on dopamine neuron firing or response to quinpirole, revealing a novel non-pharmacological interaction between adenosine a(2a) receptors and dopaminergic neurotransmission in midbrain dopamine neurons. |
2012-07-05 |
2023-08-12 |
mouse |
| Ning Guo, Wei Yao, Shi-Rong Wang, Jun Zhu, Dong Huang, Pan-Li Zuo, Xin-Jiang Kang, Chong-Luo Fu, Zhuan Zhou, Bo Zhan. Nicotine dynamically modulates dopamine clearance in rat striatum in vivo. Neurochemistry international. vol 60. issue 4. 2012-07-05. PMID:22310173. |
nicotine binds to nicotinic acetylcholine receptors on dopaminergic terminals to evoke dopamine (da) release. |
2012-07-05 |
2023-08-12 |
rat |
| Peter Podhorec, Magdalena Socha, Miroslawa Sokolowska-Mikolajczyk, Tomas Policar, Viktor W Svinger, Borek Drozd, Jan Kouri. Dopamine control of LH release in the tench (Tinca tinca). General and comparative endocrinology. vol 175. issue 1. 2012-07-02. PMID:22094207. |
the study presents clear evidence of dopaminergic control of lh release in tench, with a high ovulation rate obtained after application of gnrha alone or in combination with dopamine inhibitor. |
2012-07-02 |
2023-08-12 |
human |
| Cécile Lavoute, Michel Weiss, Jean-Jacques Risso, Jean-Claude Rostai. Mechanism of action of nitrogen pressure in controlling striatal dopamine level of freely moving rats is changed by recurrent exposures to nitrogen narcosis. Neurochemical research. vol 37. issue 3. 2012-06-29. PMID:22127756. |
after repeated exposure to nitrogen narcosis, a second exposure to 3 mpa increased dopamine levels suggesting a change in the control of the dopaminergic pathway. |
2012-06-29 |
2023-08-12 |
rat |
| Anjali Rao, Toni L Richards, Diana Simmons, Nancy R Zahniser, Alexander Sorki. Epitope-tagged dopamine transporter knock-in mice reveal rapid endocytic trafficking and filopodia targeting of the transporter in dopaminergic axons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 5. 2012-06-29. PMID:22267337. |
epitope-tagged dopamine transporter knock-in mice reveal rapid endocytic trafficking and filopodia targeting of the transporter in dopaminergic axons. |
2012-06-29 |
2023-08-12 |
mouse |
| Floriana Volpicelli, Roberto De Gregorio, Salvatore Pulcrano, Carla Perrone-Capano, Umberto di Porzio, Gian Carlo Bellench. Direct regulation of Pitx3 expression by Nurr1 in culture and in developing mouse midbrain. PloS one. vol 7. issue 2. 2012-06-29. PMID:22363463. |
during development the expression of nurr1 precedes that of pitx3 and those of typical dopaminergic markers such as tyrosine hydroxylase (th) and dopamine transporter (dat) that are directly regulated by nurr1. |
2012-06-29 |
2023-08-12 |
mouse |
| Daniela Hernandez, Ciara A Torres, Wanda Setlik, Carolina Cebrián, Eugene V Mosharov, Guomei Tang, Hsiao-Chun Cheng, Nikolai Kholodilov, Olga Yarygina, Robert E Burke, Michael Gershon, David Sulze. Regulation of presynaptic neurotransmission by macroautophagy. Neuron. vol 74. issue 2. 2012-06-29. PMID:22542182. |
we find that the mtor inhibitor rapamycin induces formation of autophagic vacuoles in prejunctional dopaminergic axons with associated decreased axonal profile volumes, synaptic vesicle numbers, and evoked dopamine release. |
2012-06-29 |
2023-08-12 |
mouse |
| Daniela Hernandez, Ciara A Torres, Wanda Setlik, Carolina Cebrián, Eugene V Mosharov, Guomei Tang, Hsiao-Chun Cheng, Nikolai Kholodilov, Olga Yarygina, Robert E Burke, Michael Gershon, David Sulze. Regulation of presynaptic neurotransmission by macroautophagy. Neuron. vol 74. issue 2. 2012-06-29. PMID:22542182. |
evoked dopamine secretion was enhanced and recovery was accelerated in transgenic mice in which macroautophagy deficiency was restricted to dopaminergic neurons; rapamycin failed to decrease evoked dopamine release in the striatum of these mice. |
2012-06-29 |
2023-08-12 |
mouse |
| N R Ferreira, M Mitkovski, W Stühmer, L A Pardo, E A Del Be. Ether-à-go-go 1 (Eag1) potassium channel expression in dopaminergic neurons of basal ganglia is modulated by 6-hydroxydopamine lesion. Neurotoxicity research. vol 21. issue 3. 2012-06-26. PMID:22048886. |
as dopamine may directly affect k(+) channels, we evaluated whether a nigrostriatal dopaminergic lesion induced by the neurotoxin 6-hydroxydopamine (6-ohda) would alter eag1-k(+) channel expression in the rat basal ganglia and related brain regions. |
2012-06-26 |
2023-08-12 |
rat |
| Lisa M McFadden, Samantha Carter, Leslie Matuszewic. Juvenile exposure to methamphetamine attenuates behavioral and neurochemical responses to methamphetamine in adult rats. Behavioural brain research. vol 229. issue 1. 2012-06-26. PMID:22261020. |
the long-term effects of this early exposure on the dopaminergic systems are unknown, but may be important for adult behaviors mediated by dopamine, such as drug addiction. |
2012-06-26 |
2023-08-12 |
rat |
| S K Kidd, J S Schneide. Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Neuroscience. vol 194. 2012-06-25. PMID:21846494. |
the use of animal models (including the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine [mptp] mouse model) to mimic dopaminergic (daergic) cell loss and striatal dopamine (da) depletion, as seen in parkinson's disease (pd), has implicated a multitude of factors that might be associated with daergic cell death in pd including excitotoxicity, inflammation, and oxidative stress. |
2012-06-25 |
2023-08-12 |
mouse |
| Annabelle R Charbit, Simon Akerman, Peter J Goadsb. Trigeminocervical complex responses after lesioning dopaminergic A11 nucleus are modified by dopamine and serotonin mechanisms. Pain. vol 152. issue 10. 2012-06-25. PMID:21868165. |
trigeminocervical complex responses after lesioning dopaminergic a11 nucleus are modified by dopamine and serotonin mechanisms. |
2012-06-25 |
2023-08-12 |
rat |
| Eugénie Lhommée, Hélène Klinger, Stéphane Thobois, Emmanuelle Schmitt, Claire Ardouin, Amélie Bichon, Andrea Kistner, Valérie Fraix, Jing Xie, Magaly Aya Kombo, Stephan Chabardès, Eric Seigneuret, Alim-Louis Benabid, Patrick Mertens, Gustavo Polo, Sebastien Carnicella, Jean-Louis Quesada, Jean-Luc Bosson, Emmanuel Broussolle, Pierre Pollak, Paul Krac. Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours. Brain : a journal of neurology. vol 135. issue Pt 5. 2012-06-25. PMID:22508959. |
preoperative dopamine dysregulation syndrome had disappeared in 4/4, behavioural addictions in 17/17 and compulsive dopaminergic medication use in 9/9 patients. |
2012-06-25 |
2023-08-12 |
Not clear |
| Caroline C Smith, Robert W Green. CNS dopamine transmission mediated by noradrenergic innervation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 18. 2012-06-25. PMID:22553014. |
the presynaptic source of dopamine in the ca1 field of dorsal hippocampus is uncertain due to an anatomical mismatch between dopaminergic terminals and receptors. |
2012-06-25 |
2023-08-12 |
mouse |
| Joanne Voisey, Christopher D Swagell, Ian P Hughes, Bruce R Lawford, Ross McD Young, Charles Phillip Morri. A novel DRD2 single-nucleotide polymorphism associated with schizophrenia predicts age of onset: HapMap tag-single-nucleotide polymorphism analysis. Genetic testing and molecular biomarkers. vol 16. issue 2. 2012-06-22. PMID:21861710. |
dopamine d2 receptor (drd2) is thought to be critical in regulating the dopaminergic pathway in the brain, which is known to be important in the etiology of schizophrenia. |
2012-06-22 |
2023-08-12 |
Not clear |