| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas T Hill. Animal foraging and the evolution of goal-directed cognition. Cognitive science. vol 30. issue 1. 2012-10-02. PMID:21702807. |
the evolutionary role of dopamine in the modulation of goal-directed behavior and cognition is further supported by pathologies of human goal-directed cognition, which have motor and cognitive dysfunction and organize themselves, with respect to dopaminergic activity, along the gradient described by ars, from perseverative to unfocused. |
2012-10-02 |
2023-08-12 |
human |
| C Reavill, I P Stolerma. Interaction of nicotine with dopaminergic mechanisms assessed through drug discrimination and rotational behaviour in rats. Journal of psychopharmacology (Oxford, England). vol 1. issue 4. 2012-10-02. PMID:22159140. |
biochemical and electrophysiological studies have suggested that nicotine may interact with dopaminergic systems so as to enhance the release and utilization of dopamine. |
2012-10-02 |
2023-08-12 |
rat |
| Pratima Pandey, Singh Harbinde. The Caenorhabditis elegans D2-like dopamine receptor DOP-2 physically interacts with GPA-14, a Gαi subunit. Journal of molecular signaling. vol 7. issue 1. 2012-10-02. PMID:22280843. |
dopaminergic inputs are sensed on the cell surface by the seven-transmembrane dopamine receptors that belong to a superfamily of g-protein-coupled receptors (gpcrs). |
2012-10-02 |
2023-08-12 |
caenorhabditis_elegans |
| Kjartan F Herrik, John P Redrobe, Dorte Holst, Charlotte Hougaard, Karin Sandager-Nielsen, Alexander N Nielsen, Huifang Ji, Nina M Holst, Hanne B Rasmussen, Elsebet Ø Nielsen, Dorte Strøbæk, Paul D Shepard, Palle Christopherse. CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate. Frontiers in pharmacology. vol 3. 2012-10-02. PMID:22347859. |
cyppa, a positive sk3/sk2 modulator, reduces activity of dopaminergic neurons, inhibits dopamine release, and counteracts hyperdopaminergic behaviors induced by methylphenidate. |
2012-10-02 |
2023-08-12 |
mouse |
| Diana C Ferrari, Baya J Mdzomba, Nathalie Dehorter, Catherine Lopez, François J Michel, Frédéric Libersat, Constance Hammon. Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. Frontiers in cellular neuroscience. vol 6. 2012-10-02. PMID:22408606. |
midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. |
2012-10-02 |
2023-08-12 |
mouse |
| Diana C Ferrari, Baya J Mdzomba, Nathalie Dehorter, Catherine Lopez, François J Michel, Frédéric Libersat, Constance Hammon. Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. Frontiers in cellular neuroscience. vol 6. 2012-10-02. PMID:22408606. |
at that stage (e18-p0), dopaminergic terminals release dopamine in a calcium-dependent manner in the striatum in response to local stimulation. |
2012-10-02 |
2023-08-12 |
mouse |
| Emma Perez-Costas, Miguel Melendez-Ferro, Matthew W Rice, Robert R Conley, Rosalinda C Robert. Dopamine pathology in schizophrenia: analysis of total and phosphorylated tyrosine hydroxylase in the substantia nigra. Frontiers in psychiatry. vol 3. 2012-10-02. PMID:22509170. |
despite the importance of dopamine neurotransmission in schizophrenia, very few studies have addressed anomalies in the mesencephalic dopaminergic neurons of the substantia nigra/ventral tegmental area (sn/vta). |
2012-10-02 |
2023-08-12 |
Not clear |
| Emma Perez-Costas, Miguel Melendez-Ferro, Matthew W Rice, Robert R Conley, Rosalinda C Robert. Dopamine pathology in schizophrenia: analysis of total and phosphorylated tyrosine hydroxylase in the substantia nigra. Frontiers in psychiatry. vol 3. 2012-10-02. PMID:22509170. |
tyrosine hydroxylase (th) is the rate-limiting enzyme for the production of dopamine, and a possible contributor to the anomalies in the dopaminergic neurotransmission observed in schizophrenia. |
2012-10-02 |
2023-08-12 |
Not clear |
| Jin Mizushima, Keisuke Takahata, Noriko Kawashima, Motoichiro Kat. Successful treatment of dopamine dysregulation syndrome with dopamine D2 partial agonist antipsychotic drug. Annals of general psychiatry. vol 11. issue 1. 2012-10-02. PMID:22769562. |
dopamine dysregulation syndrome (dds) consists of a series of complications such as compulsive use of dopaminergic medications, aggressive or hypomanic behaviors during excessive use, and withdrawal states characterized by dysphoria and anxiety, caused by long-term dopaminergic treatment in patients with parkinson's disease (pd). |
2012-10-02 |
2023-08-12 |
Not clear |
| Michael C Reed, H Frederik Nijhout, Janet A Bes. Mathematical insights into the effects of levodopa. Frontiers in integrative neuroscience. vol 6. 2012-10-02. PMID:22783173. |
we use a mathematical model to investigate the consequences of levodopa therapy on the serotonergic system and on the pulsatile release of dopamine (da) from dopaminergic and serotonergic terminals in the striatum. |
2012-10-02 |
2023-08-12 |
Not clear |
| Jeff A Beeler, Cristianne R M Frazier, Xiaoxi Zhuan. Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources. Frontiers in integrative neuroscience. vol 6. 2012-10-02. PMID:22833718. |
this hypothesis provides a mechanistic interpretation to an apparent paradox: the well-established role of dopamine in food seeking and the findings that low dopaminergic functions are associated with obesity. |
2012-10-02 |
2023-08-12 |
Not clear |
| Osnat M Ben-Shahar, Karen K Szumlinski, Kevin D Lominac, Ami Cohen, Evan Gordon, Kyle L Ploense, Jeremy DeMartini, Nicholas Bernstein, Nicole M Rudy, Ahmad N Nabhan, Arianne Sacramento, Kelly Pagano, Giovanni A Carosso, Nick Woodwar. Extended access to cocaine self-administration results in reduced glutamate function within the medial prefrontal cortex. Addiction biology. vol 17. issue 4. 2012-10-01. PMID:22339852. |
while exposure to 17 1-hour sessions also resulted in reduced basal dopamine levels, these animals showed increased dopaminergic, but completely diminished glutamatergic, response to self-administered cocaine. |
2012-10-01 |
2023-08-12 |
human |
| Osnat M Ben-Shahar, Karen K Szumlinski, Kevin D Lominac, Ami Cohen, Evan Gordon, Kyle L Ploense, Jeremy DeMartini, Nicholas Bernstein, Nicole M Rudy, Ahmad N Nabhan, Arianne Sacramento, Kelly Pagano, Giovanni A Carosso, Nick Woodwar. Extended access to cocaine self-administration results in reduced glutamate function within the medial prefrontal cortex. Addiction biology. vol 17. issue 4. 2012-10-01. PMID:22339852. |
causing a return to control levels) both the dopaminergic response to self-administered cocaine as well as basal dopamine levels within this area. |
2012-10-01 |
2023-08-12 |
human |
| Yan-Fen Zhang, Xiao-Yu Wang, Feng Guo, Kristin Burns, Qi-Yong Guo, Xiao-Ming Wan. Simultaneously changes in striatum dopaminergic and glutamatergic parameters following hypoxic-ischemic neuronal injury in newborn piglets. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 16. issue 3. 2012-09-28. PMID:21723167. |
our findings suggest that following h-i brain insult, striatal d2r positive neurons decreased due to neuron death; straital dat initially increased to compensate for dopamine uptake; and glutamatergic and dopaminergic systems in striatum may act in an interdependent way in the striatum of newborn piglets. |
2012-09-28 |
2023-08-12 |
Not clear |
| Tony J Sapsford, Ilona C Kokay, Lovisa Ostberg, Robert S Bridges, David R Gratta. Differential sensitivity of specific neuronal populations of the rat hypothalamus to prolactin action. The Journal of comparative neurology. vol 520. issue 5. 2012-09-28. PMID:21953590. |
prolactin stimulates dopamine release from neuroendocrine dopaminergic (neda) neurons in the hypothalamic arcuate nucleus (arc) to maintain low levels of serum prolactin. |
2012-09-28 |
2023-08-12 |
rat |
| Warren H Meck, Ruey-Kuang Cheng, Christopher J MacDonald, Raul R Gainetdinov, Marc G Caron, Münire Özlem Cevi. Gene-dose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice. Neuropharmacology. vol 62. issue 3. 2012-09-27. PMID:21296093. |
the dopamine transporter (dat) is the major regulator of the spatial and temporal resolution of dopaminergic neurotransmission in the brain. |
2012-09-27 |
2023-08-12 |
mouse |
| Wendi S Neckameyer, Parag Bhat. Neurotrophic actions of dopamine on the development of a serotonergic feeding circuit in Drosophila melanogaster. BMC neuroscience. vol 13. 2012-09-27. PMID:22413901. |
dopamine does not modulate larval feeding, and dopaminergic fibers do not innervate the larval foregut. |
2012-09-27 |
2023-08-12 |
drosophila_melanogaster |
| Monica L Andersen, Eileen K Sawyer, Leonard L Howel. Contributions of neuroimaging to understanding sex differences in cocaine abuse. Experimental and clinical psychopharmacology. vol 20. issue 1. 2012-09-26. PMID:21875225. |
spect and pet studies have demonstrated changes in the dopamine transporter but are less clear on other components of the dopaminergic system. |
2012-09-26 |
2023-08-12 |
human |
| Naila Rasheed, Abdullah Alghasha. Central dopaminergic system and its implications in stress-mediated neurological disorders and gastric ulcers: short review. Advances in pharmacological sciences. vol 2012. 2012-09-26. PMID:23008702. |
for decades, it has been suggested that dysfunction of dopaminergic pathways and their associated modulations in dopamine levels play a major role in the pathogenesis of neurological disorders. |
2012-09-26 |
2023-08-12 |
Not clear |
| Kelly A Meulendyke, Mikhail V Pletnikov, Elizabeth L Engle, Patrick M Tarwater, David R Graham, M Christine Zin. Early minocycline treatment prevents a decrease in striatal dopamine in an SIV model of HIV-associated neurological disease. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 2. 2012-09-24. PMID:22198699. |
da decline was not due to direct loss of dopaminergic projections to the basal ganglia as there was no difference in tyrosine hydroxylase, dopamine transporter, vesicular monoamine transporter 2 or synaptophysin between minocycline-treated and untreated macaques. |
2012-09-24 |
2023-08-12 |
Not clear |