| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Weintraub, Melissa J Nirenber. Impulse control and related disorders in Parkinson's disease. Neuro-degenerative diseases. vol 11. issue 2. 2013-04-30. PMID:23038208. |
other impulsive-compulsive behaviors have been linked to dopaminergic medications; these include punding (stereotyped, repetitive, purposeless behaviors) and dopamine dysregulation syndrome (dds; compulsive medication overuse). |
2013-04-30 |
2023-08-12 |
Not clear |
| Daniel Weintraub, Melissa J Nirenber. Impulse control and related disorders in Parkinson's disease. Neuro-degenerative diseases. vol 11. issue 2. 2013-04-30. PMID:23038208. |
icds have been most closely related to the use of dopamine agonists (das), particularly at higher dosages; in contrast, dds is primarily associated with shorter-acting, higher-potency dopaminergic medications, such as apomorphine and levodopa. |
2013-04-30 |
2023-08-12 |
Not clear |
| Valtteri Kaasinen, Pekka Jokinen, Juho Joutsa, Olli Eskola, Juha O Rinn. Seasonality of striatal dopamine synthesis capacity in Parkinson's disease. Neuroscience letters. vol 530. issue 1. 2013-04-30. PMID:23041046. |
recent neuroimaging evidence suggests that the healthy human brain dopaminergic system may show seasonal rhythmicity, as striatal dopamine synthesis capacity has been reported to be higher during fall and winter. |
2013-04-30 |
2023-08-12 |
human |
| R Pattarini, Y Rong, K R Shepherd, Y Jiao, C Qu, R J Smeyne, J I Morga. Long-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine. Neuroscience. vol 214. 2013-04-29. PMID:22542874. |
the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine (mptp) induces pathological features of pd including loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and striatal dopamine (da) depletion. |
2013-04-29 |
2023-08-12 |
mouse |
| Maurizio F Facheris, Andrew A Hicks, Peter P Pramstaller, Irene Pichle. Update on the management of restless legs syndrome: existing and emerging treatment options. Nature and science of sleep. vol 2. 2013-04-26. PMID:23616710. |
rls patients have lower dopamine and iron levels in the substantia nigra and respond to both dopaminergic therapy and iron administration. |
2013-04-26 |
2023-08-12 |
Not clear |
| Ramón Sotomayor-Zárate, Gabriel Quiroz, Katherine A Araya, Jorge Abarca, María R Ibáñez, Alejandro Montecinos, Carlos Guajardo, Gabriel Núñez, Angélica Fierro, Pablo R Moya, Patricio Iturriaga-Vásquez, Cristóbal Gómez-Molina, Katia Gysling, Miguel Reyes-Parad. 4-Methylthioamphetamine increases dopamine in the rat striatum and has rewarding effects in vivo. Basic & clinical pharmacology & toxicology. vol 111. issue 6. 2013-04-25. PMID:22788961. |
as little is known about dopaminergic effects of this drug, in this work the actions of mta upon the dopamine (da) transporter (dat) were studied in vitro, in vivo and in silico. |
2013-04-25 |
2023-08-12 |
human |
| Hiroko Ikeda, Junzo Kamei, Noriaki Koshikawa, Alexander R Cool. Nucleus accumbens and dopamine-mediated turning behavior of the rat: role of accumbal non-dopaminergic receptors. Journal of pharmacological sciences. vol 120. issue 3. 2013-04-22. PMID:23059952. |
since the nucleus accumbens contains different neurotransmitters, it is important to know how they interact with dopaminergic function: this is because modifying accumbal dopamine has far-reaching consequences for the treatment of diseases in which accumbal dopamine is involved. |
2013-04-22 |
2023-08-12 |
rat |
| Peter J Gaskill, Loreto Carvallo, Eliseo A Eugenin, Joan W Berma. Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse. Journal of neuroinflammation. vol 9. 2013-04-19. PMID:22901451. |
in rodent macrophages and human t-cells, dopamine was shown to modulate cellular functions through activation of dopamine receptors and other dopaminergic proteins. |
2013-04-19 |
2023-08-12 |
human |
| Isabelle St-Amour, Mélanie Bousquet, Isabelle Paré, Janelle Drouin-Ouellet, Francesca Cicchetti, Renée Bazin, Frédéric Calo. Impact of intravenous immunoglobulin on the dopaminergic system and immune response in the acute MPTP mouse model of Parkinson's disease. Journal of neuroinflammation. vol 9. 2013-04-19. PMID:23046563. |
the mptp treatment induced significant 80% and 84% decreases of striatal dopamine concentrations (p < 0.01), as well as 33% and 40% reductions in the number of nigral dopaminergic neurons (p < 0.001) in controls and ivig-treated mice, respectively. |
2013-04-19 |
2023-08-12 |
mouse |
| Takao Nozaki, Kenji Sugiyama, Shunsuke Yagi, Etsuji Yoshikawa, Toshihiko Kanno, Tetsuya Asakawa, Tae Ito, Tatsuhiro Terada, Hiroki Namba, Yasuomi Ouch. Effect of subthalamic nucleus stimulation during exercise on the mesolimbocortical dopaminergic region in Parkinson's disease: a positron emission tomography study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 33. issue 3. 2013-04-19. PMID:23211966. |
the lack of dopamine release in the putamen and the significant dopamine release in the ventromedial striatum by stn-dbs during exercise indicated dopaminergic activation occurring in the motivational circuit during action, suggesting a compensatory functional activation of the motor loop from the nonmotor to the motor loop system. |
2013-04-19 |
2023-08-12 |
Not clear |
| Fabrizio Sanna, Antonio Argiolas, Maria Rosaria Meli. Oxytocin-induced yawning: sites of action in the brain and interaction with mesolimbic/mesocortical and incertohypothalamic dopaminergic neurons in male rats. Hormones and behavior. vol 62. issue 4. 2013-04-17. PMID:22981942. |
since oxytocin is considered a key regulator of emotional and social reward that enhances amygdala-dependent, socially reinforced learning and emotional empathy, mesolimbic and mesocortical dopamine neurons play a key role in motivation and reward, and yawning in mammals is considered a primitive, unconscious form of empathy, the present results support the hypothesis that oxytocinergic neurons originating in the paraventricular nucleus of the hypothalamus and projecting to the above brain areas and mesolimbic and mesocortical dopaminergic neurons participate in the complex neural circuits that play a role in the above mentioned functions. |
2013-04-17 |
2023-08-12 |
rat |
| Rebecca Kuepper, Mette Skinbjerg, Anissa Abi-Dargha. The dopamine dysfunction in schizophrenia revisited: new insights into topography and course. Handbook of experimental pharmacology. issue 212. 2013-04-17. PMID:23129326. |
schizophrenia has long been associated with an imbalance in dopamine (da) neurotransmission, and brain imaging has played an important role in advancing our knowledge and providing evidence for the dopaminergic abnormalities. |
2013-04-17 |
2023-08-12 |
mouse |
| Silvia V Conde, Ana Obeso, Emília C Monteiro, Constancio Gonzale. Effect of chronic caffeine intake on carotid body catecholamine dynamics in control and chronically hypoxic rats. Advances in experimental medicine and biology. vol 758. 2013-04-16. PMID:23080178. |
findings indicate that chronic caffeine ingestion in normoxic rats did not modify dopamine dynamics at the cb, but increases dopaminergic system during chronic hypoxia. |
2013-04-16 |
2023-08-12 |
rat |
| Kah-Leong Lim, Cheng-Wu Zhan. Molecular events underlying Parkinson's disease - an interwoven tapestry. Frontiers in neurology. vol 4. 2013-04-15. PMID:23580245. |
aberrations in homeostatic processes leading to protein aggregation and mitochondrial dysfunction may arise intrinsically in substantia nigra pars compacta dopaminergic neurons as a result of impairments in the ubiquitin-proteasome system, failure in autophagy-mediated clearance, alterations of mitochondrial dynamics, redox imbalance, iron mishandling, dopamine dysregulation, or simply from the chronic pace-making activity of nigra-localized l-type calcium channels, or extrinsically from non-autonomous sources of stress. |
2013-04-15 |
2023-08-12 |
human |
| Mira-Lynn Chavanon, Jan Wacker, Gerhard Stemmle. Paradoxical dopaminergic drug effects in extraversion: dose- and time-dependent effects of sulpiride on EEG theta activity. Frontiers in human neuroscience. vol 7. 2013-04-15. PMID:23580360. |
future studies may now systematically apply the model to other examples of paradoxical dopaminergic drug effects and examine the molecular basis of individual differences in pre- vs. postsynaptic dopamine d2 subreceptor sensitivities and densities. |
2013-04-15 |
2023-08-12 |
human |
| Iva Z Mathews, Cheryl M McCormic. Role of medial prefrontal cortex dopamine in age differences in response to amphetamine in rats: locomotor activity after intra-mPFC injections of dopaminergic ligands. Developmental neurobiology. vol 72. issue 11. 2013-04-11. PMID:22081646. |
role of medial prefrontal cortex dopamine in age differences in response to amphetamine in rats: locomotor activity after intra-mpfc injections of dopaminergic ligands. |
2013-04-11 |
2023-08-12 |
rat |
| R de la Fuente-Fernánde. The powerful pre-treatment effect: placebo responses in restless legs syndrome trials. European journal of neurology. vol 19. issue 10. 2013-04-11. PMID:22537387. |
to investigate whether dopaminergic pre-treatment alters placebo and dopamine agonist responses in restless legs syndrome (rls). |
2013-04-11 |
2023-08-12 |
Not clear |
| Alessia Scatena, Francesco Fornai, Maria Letizia Trincavelli, Sabrina Taliani, Simona Daniele, Isabella Pugliesi, Sandro Cosconati, Claudia Martini, Federico Da Settim. 3-(Fur-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a novel adenosine receptor antagonist with A(2A)-mediated neuroprotective effects. ACS chemical neuroscience. vol 2. issue 9. 2013-04-11. PMID:22860174. |
altogether these results demonstrate that the a(2a) ar blockade mediates cell protection against neurotoxicity induced by dopaminergic neurotoxins in dopamine containing cells, supporting the potential use of a(2a) ar antagonists in dopaminergic degenerative diseases including parkinson's disease. |
2013-04-11 |
2023-08-12 |
human |
| Fengrui Li, Xiaofei Tian, Yishu Zhou, Lanhui Zhu, Baojie Wang, Mei Ding, Hao Pan. Dysregulated expression of secretogranin III is involved in neurotoxin-induced dopaminergic neuron apoptosis. Journal of neuroscience research. vol 90. issue 12. 2013-04-11. PMID:22987761. |
the neurotoxins paraquat (pq) and dopamine (da or 6-ohda) cause apoptosis of dopaminergic neurons in the substantia nigra pars compacta (snpc), reproducing an important pathological feature of parkinson's disease (pd). |
2013-04-11 |
2023-08-12 |
human |
| Narasimha M Midde, Adrian M Gomez, Jun Zh. HIV-1 Tat protein decreases dopamine transporter cell surface expression and vesicular monoamine transporter-2 function in rat striatal synaptosomes. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 3. 2013-04-10. PMID:22570010. |
the dopamine (da) transporter (dat) and vesicular monoamine transporter (vmat2) proteins interact as a biochemical complex to regulate dopaminergic neurotransmission. |
2013-04-10 |
2023-08-12 |
rat |