| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gerda Thomsen, Gitte Moos Knudsen, Peter S Jensen, Morten Ziebell, Klaus K Holst, Susanne Asenbaum, Jan Booij, Jacques Darcourt, John C Dickson, Ozlem L Kapucu, Flavio Nobili, Osama Sabri, Terez Sera, Klaus Tatsch, Livia Tossici-Bolt, Koen Van Laere, Thierry Vander Borght, Andrea Varrone, Marco Pagani, Lars Hageman Pinbor. No difference in striatal dopamine transporter availability between active smokers, ex-smokers and non-smokers using [123I]FP-CIT (DaTSCAN) and SPECT. EJNMMI research. vol 3. issue 1. 2013-06-05. PMID:23688063. |
the dopamine transporter (dat) is of central importance in regulating dopaminergic neurotransmission and in particular in activating the striatal d2-like receptors. |
2013-06-05 |
2023-08-12 |
Not clear |
| Marco A T Utiumi, André C Felício, Conrado R Borges, Vera L Braatz, Sheyla A S Rezende, Renato P Munhoz, Rodrigo A Bressan, Henrique B Ferraz, Hélio A G Teiv. Dopamine transporter imaging in clinically unclear cases of parkinsonism and the importance of scans without evidence of dopaminergic deficit (SWEDDs). Arquivos de neuro-psiquiatria. vol 70. issue 9. 2013-06-04. PMID:22990721. |
dopamine transporter imaging in clinically unclear cases of parkinsonism and the importance of scans without evidence of dopaminergic deficit (swedds). |
2013-06-04 |
2023-08-12 |
Not clear |
| Xuefeng Tan, Lei Zhang, JianBing Qin, Meiling Tian, Huixia Zhu, Chuanming Dong, Heyan Zhao, Guohua Ji. Transplantation of neural stem cells co-transfected with Nurr1 and Brn4 for treatment of Parkinsonian rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 1. 2013-05-30. PMID:23085081. |
the results showed that overexpression of nurr1 promoted nscs to differentiate into dopaminergic neurons in vivo, increased the level of dopamine (da) neurotransmitter in the striatum, resulting in behavioral improvement of pd rats. |
2013-05-30 |
2023-08-12 |
rat |
| Katsura Takano, Nobuyuki Tanaka, Kenji Kawabe, Mitsuaki Moriyama, Yoichi Nakamur. Extracellular superoxide dismutase induced by dopamine in cultured astrocytes. Neurochemical research. vol 38. issue 1. 2013-05-29. PMID:22983620. |
although dopamine (da) stored in the synaptic vesicle is stable, the excess leaked da is spontaneously oxidized to yield o(2)(-) and reactive da quinones, causing damages of dopaminergic neurons. |
2013-05-29 |
2023-08-12 |
rat |
| Javier Pagonabarraga, María Cruz Rodríguez-Oro. [Rasagiline in monotherapy in patients with early stages of Parkinson's disease and in combined and adjunct therapy to levodopa with moderate and advanced stages]. Revista de neurologia. vol 56. issue 1. 2013-05-28. PMID:23250679. |
the combination of different drugs that provide a more continuous dopaminergic stimulation (rasagiline, dopamine agonists) not only exerts a benefit through diminishing the impact of pulsatile stimulation on post-synaptic dopamine receptors, but allows to decrease total daily levodopa requirements. |
2013-05-28 |
2023-08-12 |
Not clear |
| Pia Steensland, Ida Fredriksson, Sarah Holst, Kristin Feltmann, Johan Franck, Björn Schilström, Arvid Carlsso. The monoamine stabilizer (-)-OSU6162 attenuates voluntary ethanol intake and ethanol-induced dopamine output in nucleus accumbens. Biological psychiatry. vol 72. issue 10. 2013-05-24. PMID:22817867. |
a novel approach to normalize these dysregulations might be treatment with "monoamine stabilizers," a novel class of compounds characterized by the ability to either suppress, stimulate, or not influence dopamine activity depending on the prevailing dopaminergic tone. |
2013-05-24 |
2023-08-12 |
Not clear |
| Mingli Jin, Chengchun Min, Mei Zheng, Dong-Im Cho, Soo-Jin Cheong, Hitosh Kurose, Kyeong-Man Ki. Multiple signaling routes involved in the regulation of adenylyl cyclase and extracellular regulated kinase by dopamine D(2) and D(3) receptors. Pharmacological research. vol 67. issue 1. 2013-05-23. PMID:23059541. |
dopamine d(2) and d(3) receptors (d(2)r, d(3)r), the major targets of currently used antipsychotic drugs, are co-expressed in some of the same dopaminergic neurons and regulate the same overlapping effectors. |
2013-05-23 |
2023-08-12 |
Not clear |
| Kelly A Diggs-Andrews, Kazuhiro Tokuda, Yukitoshi Izumi, Charles F Zorumski, David F Wozniak, David H Gutman. Dopamine deficiency underlies learning deficits in neurofibromatosis-1 mice. Annals of neurology. vol 73. issue 2. 2013-05-21. PMID:23225063. |
collectively, these results establish defective dopaminergic function as a contributing factor underlying impaired spatial learning and memory in children and adults with nf1, and support the use of treatments that restore normal dopamine homeostasis for select individuals. |
2013-05-21 |
2023-08-12 |
mouse |
| Briana R De Miranda, James A Miller, Ryan J Hansen, Paul J Lunghofer, Stephen Safe, Daniel L Gustafson, Dorothy Colagiovanni, Ronald B Tjalken. Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease. The Journal of pharmacology and experimental therapeutics. vol 345. issue 1. 2013-05-16. PMID:23318470. |
c-dim5 and c-dim12 given orally once daily after one week of exposure to mptp and probenecid prevented further loss of dopaminergic neurons in the substantia nigra pars compacta and striatal dopamine terminals, indicating that these compounds could be effective therapeutic agents to prevent neurodegeneration. |
2013-05-16 |
2023-08-12 |
mouse |
| A P Athanasoulia, M Ising, H Pfister, C S Mantzoros, G K Stalla, C Siever. Distinct dopaminergic personality patterns in patients with prolactinomas: a comparison with nonfunctioning pituitary adenoma patients and age- and gender-matched controls. Neuroendocrinology. vol 96. issue 3. 2013-05-09. PMID:22343218. |
patients with prolactinomas have been described as exhibiting an altered dopaminergic tone and are often treated with dopamine agonists. |
2013-05-09 |
2023-08-12 |
human |
| Yasukazu Hozumi, Masahiko Watanabe, Kaoru Got. Signaling cascade of diacylglycerol kinase β in the pituitary intermediate lobe: dopamine D2 receptor/phospholipase Cβ4/diacylglycerol kinase β/protein kinase Cα. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 58. issue 2. 2013-05-08. PMID:19826069. |
we have previously shown that diacylglycerol kinase β (dgkβ) is coexpressed with dopamine d1 and d2 receptors in medium spiny neurons of the striatum, suggesting a plausible implication of dgkβ in dopaminergic transmission. |
2013-05-08 |
2023-08-12 |
Not clear |
| Tianna Zhao, Herma Zondervan-van der Linde, Lies-Anne Severijnen, Ben A Oostra, Rob Willemsen, Vincenzo Bonifat. Dopaminergic neuronal loss and dopamine-dependent locomotor defects in Fbxo7-deficient zebrafish. PloS one. vol 7. issue 11. 2013-05-07. PMID:23133663. |
of note, the number of the dopamine transporter-expressing neurons was much more severely depleted, suggesting dopaminergic dysfunctions earlier and larger than those due to neuronal loss. |
2013-05-07 |
2023-08-12 |
human |
| Wai Chong Wong, Kerstin A Ford, Nicole E Pagels, James E McCutcheon, Michela Marinell. Adolescents are more vulnerable to cocaine addiction: behavioral and electrophysiological evidence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486962. |
in addition, to determine whether behavioral differences are associated with developmental differences in dopaminergic activity, we examined and manipulated the activity of dopamine neurons. |
2013-05-06 |
2023-08-12 |
rat |
| Roberto Erro, Sabina Pappatà, Marianna Amboni, Caterina Vicidomini, Katia Longo, Gabriella Santangelo, Marina Picillo, Carmine Vitale, Marcello Moccia, Flavio Giordano, Arturo Brunetti, Maria Teresa Pellecchia, Marco Salvatore, Paolo Baron. Anxiety is associated with striatal dopamine transporter availability in newly diagnosed untreated Parkinson's disease patients. Parkinsonism & related disorders. vol 18. issue 9. 2013-05-03. PMID:22789824. |
the aim of our study was to investigate a possible dopaminergic mechanism involved in anxiety in newly diagnosed never-medicated pd patients using spect and ¹²³i-fp-cit as the dopamine transporter ligand. |
2013-05-03 |
2023-08-12 |
Not clear |
| I Heitland, R S Oosting, J M P Baas, S A A Massar, J L Kenemans, K B E Böcke. Genetic polymorphisms of the dopamine and serotonin systems modulate the neurophysiological response to feedback and risk taking in healthy humans. Cognitive, affective & behavioral neuroscience. vol 12. issue 4. 2013-05-03. PMID:22810728. |
here, we studied the effects of dopaminergic (dopamine transporter [dat1], catecholamine-o-methyltransferase val158met [comt]) and serotonergic (serotonin transporter [5httlpr]) polymorphisms on risk taking and brain responses following feedback in 60 healthy female subjects. |
2013-05-03 |
2023-08-12 |
human |
| Alireza Soltani, Behrad Noudoost, Tirin Moor. Dissociable dopaminergic control of saccadic target selection and its implications for reward modulation. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 9. 2013-05-02. PMID:23401524. |
altogether, these results reveal dissociable dopaminergic mechanisms influencing target selection and suggest how reward can influence adaptive choice behavior via prefrontal dopamine. |
2013-05-02 |
2023-08-12 |
monkey |
| Tiago A Mestre, Antonio P Strafella, Teri Thomsen, Valerie Voon, Janis Miyasak. Diagnosis and treatment of impulse control disorders in patients with movement disorders. Therapeutic advances in neurological disorders. vol 6. issue 3. 2013-05-02. PMID:23634190. |
in movement disorders, impulse control disorders are associated with dopaminergic treatment, notably dopamine agonists (das). |
2013-05-02 |
2023-08-12 |
Not clear |
| Chiara Bianca Maria Platania, Salvatore Salomone, Gian Marco Leggio, Filippo Drago, Claudio Bucol. Homology modeling of dopamine D2 and D3 receptors: molecular dynamics refinement and docking evaluation. PloS one. vol 7. issue 9. 2013-05-01. PMID:22970199. |
in conclusion, the present computational approach seems suitable to build and refine structure models of homologous dopamine receptors that may be of value for structure-based drug discovery of selective dopaminergic ligands. |
2013-05-01 |
2023-08-12 |
human |
| Pilar Almela, Javier Navarro-Zaragoza, Juan-Antonio García-Carmona, Lucía Mora, Juana Hidalgo, María-Victoria Milanés, María-Luisa Laorde. Role of corticotropin-releasing factor (CRF) receptor-1 on the catecholaminergic response to morphine withdrawal in the nucleus accumbens (NAc). PloS one. vol 7. issue 10. 2013-05-01. PMID:23071721. |
the effects of naloxone-precipitated morphine withdrawal on signs of withdrawal, hypothalamo-pituitary-adrenocortical (hpa) axis activity, dopamine (da) and noradrenaline (na) turnover in the nucleus accumbens (nac) and activation of vta dopaminergic neurons, were investigated in rats pretreated with vehicle or cp-154,526 (selective crf1r antagonist). |
2013-05-01 |
2023-08-12 |
rat |
| Wei-Li Chang, Martin Weber, Michelle R Breier, Richard L Saint Marie, Samantha R Hines, Neal R Swerdlo. Stereochemical and neuroanatomical selectivity of pramipexole effects on sensorimotor gating in rats. Brain research. vol 1437. 2013-04-30. PMID:22227455. |
in rats, prepulse inhibition (ppi) of acoustic startle is disrupted by systemic administration of dopaminergic agonists, such as the dopamine d3 receptor (d3r)-preferential agonist pramipexole (ppx). |
2013-04-30 |
2023-08-12 |
rat |