| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dominik K Biezonski, Brian J Piper, Nina M Shinday, Peter J Kim, Syed F Ali, Jerrold S Meye. Effects of a short-course MDMA binge on dopamine transporter binding and on levels of dopamine and its metabolites in adult male rats. European journal of pharmacology. vol 701. issue 1-3. 2013-08-22. PMID:23276666. |
the objective of this study was to determine the influence of mdma on subsequent levels of two different markers of dopaminergic function, the dopamine transporter (dat) as well as dopamine and its major metabolites. |
2013-08-22 |
2023-08-12 |
rat |
| Sudarat Nimitvilai, Devinder S Arora, Maureen A McElvain, Mark S Brodi. Ethanol blocks the reversal of prolonged dopamine inhibition of dopaminergic neurons of the ventral tegmental area. Alcoholism, clinical and experimental research. vol 36. issue 11. 2013-08-20. PMID:22551160. |
ethanol blocks the reversal of prolonged dopamine inhibition of dopaminergic neurons of the ventral tegmental area. |
2013-08-20 |
2023-08-12 |
Not clear |
| Polina Petkova-Kirova, Maria Grazia Giovannini, Reni Kalfin, Angelina Rakovsk. Modulation of acetylcholine release by cholecystokinin in striatum: receptor specificity; role of dopaminergic neuronal activity. Brain research bulletin. vol 89. issue 5-6. 2013-08-16. PMID:22981453. |
a similar increase was observed after depletion of endogenous dopamine (da) from nigro-striatal dopaminergic neurons with 6-hydroxydopamine (6-ohda) (2× 250μg/animal, i.c.v.). |
2013-08-16 |
2023-08-12 |
rat |
| Marco Cosentino, Franca Marin. Adrenergic and dopaminergic modulation of immunity in multiple sclerosis: teaching old drugs new tricks? Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 8. issue 1. 2013-08-16. PMID:23074017. |
available evidence is summarized and discussed also in the light of the novel role of dopamine, noradrenaline and adrenaline as transmitters in immune cells, providing a conceptual frame to exploit the potential of several dopaminergic and adrenergic agents, already in clinical use for non-immune indications and with a usually favourable risk-benefit profile, as add-on drugs to conventional immunomodulating therapies in ms. |
2013-08-16 |
2023-08-12 |
Not clear |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
here, using an embryonic stem cell in vitro differentiation system and mutant dreher mouse, we showed that lmx1a, an early regulator of midbrain dopamine neural progenitor phenotype specification, is also involved in the regulation of midbrain dopaminergic maturation by regulating gene expression of the dopamine transporter. |
2013-08-14 |
2023-08-12 |
mouse |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
forced expression of lmx1a induced dopamine transporter expression precociously in immature dopaminergic neurons, accompanied by significant increase in specific dopamine uptake. |
2013-08-14 |
2023-08-12 |
mouse |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
furthermore, during mouse embryonic development, dopamine transporter was more severely affected by lmx1a mutation compared to other dopamine markers such as tyrosine hydroxylase and dopa decarboxylase, again supporting the role of lmx1a in midbrain dopaminergic maturation in vivo. |
2013-08-14 |
2023-08-12 |
mouse |
| Sangmi Chung, Chun-Hyung Kim, Kwang-Soo Ki. Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development. Journal of neurochemistry. vol 122. issue 2. 2013-08-14. PMID:22564125. |
thus, this study demonstrates that dopamine transporter is a direct target of lmx1a and emphasizes a novel role of lmx1a as one of regulators of mature midbrain dopaminergic neurotransmitter phenotypes. |
2013-08-14 |
2023-08-12 |
mouse |
| Alex A MacDonald, Oury Monchi, Ken N Seergobin, Hooman Ganjavi, Ruzbeh Tamjeedi, Penny A MacDonal. Parkinson's disease duration determines effect of dopaminergic therapy on ventral striatum function. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 2. 2013-08-06. PMID:23165957. |
we investigated the hypothesis that variation in endogenous dopamine (da) across brain regions explains dissimilar effects of dopaminergic therapy on aspects of cognition in early parkinson's disease (pd). |
2013-08-06 |
2023-08-12 |
Not clear |
| Alex A MacDonald, Oury Monchi, Ken N Seergobin, Hooman Ganjavi, Ruzbeh Tamjeedi, Penny A MacDonal. Parkinson's disease duration determines effect of dopaminergic therapy on ventral striatum function. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 2. 2013-08-06. PMID:23165957. |
furthermore, dopaminergic medication did not worsen reward learning in late pd patients, in line with the dopamine overdose hypothesis. |
2013-08-06 |
2023-08-12 |
Not clear |
| Lorraine V Kalia, Jonathan M Brotchie, Susan H Fo. Novel nondopaminergic targets for motor features of Parkinson's disease: review of recent trials. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 2. 2013-08-06. PMID:23225267. |
neurotransmitters other than dopamine are recognized as having modulatory roles within the basal ganglia and can influence the basal ganglia dopaminergic system to alter activity of the direct and indirect pathways. |
2013-08-06 |
2023-08-12 |
Not clear |
| John P M Finber. Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson's Disease with Neuroprotective Potential. Rambam Maimonides medical journal. vol 1. issue 1. 2013-08-05. PMID:23908775. |
although the exact distribution of mao isoforms in different neurons and tissues is not known, dopamine behaves largely as a mao-a substrate in vivo, but following loss of dopaminergic axonal varicosities from the striatum, metabolism by glial mao-b becomes increasingly important. |
2013-08-05 |
2023-08-12 |
human |
| Kenji Morita, Mieko Morishima, Katsuyuki Sakai, Yasuo Kawaguch. Dopaminergic control of motivation and reinforcement learning: a closed-circuit account for reward-oriented behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678129. |
however, previous attempts to elucidate the mechanisms of these dopaminergic controls have not fully explained how the motivational and learning aspects are related and whether they can be understood by the way the activity of dopamine neurons itself is controlled by their upstream circuitries. |
2013-08-02 |
2023-08-12 |
Not clear |
| Nagaraja Haleagrahara, Cheng Jun Siew, Kumar Ponnusam. Effect of quercetin and desferrioxamine on 6-hydroxydopamine (6-OHDA) induced neurotoxicity in striatum of rats. The Journal of toxicological sciences. vol 38. issue 1. 2013-08-01. PMID:23358137. |
in conclusion, an antioxidant with iron chelator treatment showed a significant neuroprotective effect against 6-hydroxydopamine (6-ohda) by preventing dopaminergic neuronal loss and maintaining the striatal dopamine level. |
2013-08-01 |
2023-08-12 |
rat |
| Trent U Steidinger, Sunny R Slone, Huiping Ding, David G Standaert, Talene A Yacoubia. Angiogenin in Parkinson disease models: role of Akt phosphorylation and evaluation of AAV-mediated angiogenin expression in MPTP treated mice. PloS one. vol 8. issue 2. 2013-07-29. PMID:23409128. |
we found that angiogenin overexpression using this approach does not reduce the mptp-induced degeneration of dopaminergic cells in the substantia nigra, nor limit the depletion of dopamine and its metabolites in the striatum. |
2013-07-29 |
2023-08-12 |
mouse |
| Xiaochu Zhang, Mary R Lee, Betty Jo Salmeron, Dan J Stein, L Elliot Hong, Xiujuan Geng, Thomas J Ross, Nan Li, Colin Hodgkinson, Pei-Hong Shen, Yihong Yang, David Goldman, Elliot A Stei. Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism. NeuroImage. vol 69. 2013-07-26. PMID:23219927. |
prefrontal dopaminergic tone is under genetic control and is influenced by and modulates descending cortico-striatal glutamatergic pathways that in turn, regulate striatal dopamine release. |
2013-07-26 |
2023-08-12 |
Not clear |
| K Barreto-Valer, R López-Bellido, R E Rodrígue. Cocaine modulates the expression of transcription factors related to the dopaminergic system in zebrafish. Neuroscience. vol 231. 2013-07-25. PMID:23219907. |
nodal-related protein, ndr2, and transcription factors such as lmx1b, otp, nurr1 and pitx3 are very important in the differentiation, function and maintenance of mesodiencephalic dopaminergic neurons, and are necessary for the activation of tyrosine hydroxylase (th) and dopamine (da) transporter expression. |
2013-07-25 |
2023-08-12 |
zebrafish |
| Joanne Clark, Jessica M Silvaggi, Tomas Kiselak, Kangni Zheng, Elizabeth L Clore, Ying Dai, Caroline E Bass, David K Simo. Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf. PloS one. vol 7. issue 11. 2013-07-24. PMID:23145024. |
overexpression of pgc-1α in the sn induced expression of target genes, but unexpectedly it also greatly reduced the expression of tyrosine hydroxylase (th) and other markers of the dopaminergic phenotype with resultant severe loss of striatal dopamine. |
2013-07-24 |
2023-08-12 |
mouse |
| Elise Metereau, Jean-Claude Drehe. Cerebral correlates of salient prediction error for different rewards and punishments. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 2. 2013-07-22. PMID:22368086. |
recent electrophysiological studies reported that during a pavlovian procedure some dopamine neurons code a classical pe signal while a larger population of dopaminergic neurons reflect a "salient" prediction error (spe) signal, being excited both by unpredictable aversive events and by rewards. |
2013-07-22 |
2023-08-12 |
human |
| Maria Thereza Gamberini, Maria Laura Bolognesi, Antonia Gladys Nasell. The modulatory role of M2 muscarinic receptor on apomorphine-induced yawning and genital grooming. Neuroscience letters. vol 531. issue 2. 2013-07-22. PMID:23041487. |
in the brain, m2 receptors are found predominantly in presynaptic cholinergic neurons as autoreceptors, and in dopaminergic neurons as heteroceptors, suggesting a control role of acetylcholine and dopamine release, respectively. |
2013-07-22 |
2023-08-12 |
rat |