| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chang-Youl Park, Shin-Ho Lee, Bo-Kyun Kim, Mal-Soon Shin, Chang-Ju Kim, Hong Ki. Treadmill exercise ameliorates impairment of spatial learning ability through enhancing dopamine expression in hypoxic ischemia brain injury in neonatal rats. Journal of exercise rehabilitation. vol 9. issue 4. 2013-11-26. PMID:24278893. |
in this study, hypoxic ischemia injury caused loss of dopamine neurons in the substantia nigra and dopaminergic fibers in the striatum. |
2013-11-26 |
2023-08-12 |
rat |
| Jun Wang, Raphaël Trouillon, Yuqing Lin, Maria I Svensson, Andrew G Ewin. Individually addressable thin-film ultramicroelectrode array for spatial measurements of single vesicle release. Analytical chemistry. vol 85. issue 11. 2013-11-22. PMID:23627439. |
in contrast to previous single-cell experiments, the effect of dopaminergic drugs on imaging single vesicle exocytotic release from pc12 cell clusters is presented at cell clusters incubated with the dopamine precursor and parkinson's therapy agent, l-3,4-dihydroxyphenylalanine, and at cell clusters incubated with the vesicular monoamine transport inhibitor, reserpine. |
2013-11-22 |
2023-08-12 |
Not clear |
| Assad Assadi, Mohammad Reza Zarrindast, Abolghasem Jouyban, Morteza Samin. Comparing of the effects of hypericin and synthetic antidepressants on the expression of morphine-induced conditioned place preference. Iranian journal of pharmaceutical research : IJPR. vol 10. issue 3. 2013-11-19. PMID:24250400. |
serotonin is also a potent stimulator of dopamine release in such a way that an increase in brain serotonin could possibly stimulate the dopaminergic system. |
2013-11-19 |
2023-08-12 |
rat |
| Shaheen Jafri Ali, Padmanabhan Sharda Rajin. Elicitation of dopaminergic features of Parkinson's disease in C. elegans by monocrotophos, an organophosphorous insecticide. CNS & neurological disorders drug targets. vol 11. issue 8. 2013-11-18. PMID:23244418. |
in the present study, caenorhabditis elegans was selected as the model organism to evaluate the potential of monocrotophos (mcp), an opi, to elicit dopaminergic features of parkinson's disease in terms of dopamine content, basic movement and integrity of dopaminergic neurons along with its effect on acetylcholinesterase (ache) activity and life span. |
2013-11-18 |
2023-08-12 |
human |
| Jakob Linne. The Iowa Gambling Task and the three fallacies of dopamine in gambling disorder. Frontiers in psychology. vol 4. 2013-11-18. PMID:24115941. |
instead, dopaminergic coding of reward prediction and uncertainty might better account for dopamine dysfunctions in gambling disorder. |
2013-11-18 |
2023-08-12 |
Not clear |
| Mariah J Lelos, Eilís Dowd, Stephen B Dunnet. Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible? Progress in brain research. vol 200. 2013-11-15. PMID:23195417. |
in this chapter, we identify nonmotor impairments associated predominately with dopaminergic dysmodulation, evaluate the few emerging studies that have identified a role for dopamine and nigral transplantation in nonmotor performance, and consider a number of outstanding questions and considerations dominating the field of nigral transplantation today. |
2013-11-15 |
2023-08-12 |
Not clear |
| b' Nadia Schendzielorz, Juha-Pekka Oinas, Timo T My\\xc3\\xb6h\\xc3\\xa4nen, Ilkka Reenil\\xc3\\xa4, Atso Raasmaja, Pekka T M\\xc3\\xa4nnist\\xc3\\xb. Catechol-O-methyltransferase (COMT) protein expression and activity after dopaminergic and noradrenergic lesions of the rat brain. PloS one. vol 8. issue 4. 2013-11-14. PMID:23613844.' |
destruction of dopaminergic and noradrenergic neurons was assessed by measuring the dopamine and noradrenaline content in the projection areas of these neurons. |
2013-11-14 |
2023-08-12 |
rat |
| C Saligaut, T Bailhache, G Salbert, B Breton, P Jeg. Dynamic characteristics of serotonin and dopamine metabolism in the rainbow trout brain: a regional study using liquid chromatography with electrochemical detection. Fish physiology and biochemistry. vol 8. issue 3. 2013-11-14. PMID:24221982. |
3 methoxytyramine (3mt) was the major dopaminergic catabolite, suggesting that catechol-o-methyl transferase is the main dopamine (da) catabolic enzyme. |
2013-11-14 |
2023-08-12 |
Not clear |
| Joana Reis, Igor Encarnação, Alexandra Gaspar, Aliuska Morales, Nuno Milhazes, Fernanda Borge. Parkinson's disease management. Part II- discovery of MAO-B inhibitors based on nitrogen heterocycles and analogues. Current topics in medicinal chemistry. vol 12. issue 20. 2013-11-13. PMID:23231391. |
despite all the recent research, there are only a few classes of drugs approved for the treatment of motor related symptoms of pd which primarily act on the dopaminergic neurons system: l-dopa, dopamine agonists, monoamine oxidase-b (mao-b) and catechol-o-methyl transferase (comt) inhibitors. |
2013-11-13 |
2023-08-12 |
human |
| D N Voronkov, R M Khudoerkov, E L Dovedov. [Changes in neuroglial interactions in the cerebral nigrostriatal structures in a model of dopamine system dysfunction]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 113. issue 7. 2013-11-12. PMID:23994921. |
it has been supposed that the activation of astroglia by reserpine in a dopamine hypofunction model is caused by the dysfunction of the corticostriatal glutamatergic system as a result of inhibition of the dopaminergic transmission in the basal nuclei. |
2013-11-12 |
2023-08-12 |
rat |
| Kristin M Pearson-Fuhrhop, Brian Minton, Daniel Acevedo, Babak Shahbaba, Steven C Crame. Genetic variation in the human brain dopamine system influences motor learning and its modulation by L-Dopa. PloS one. vol 8. issue 4. 2013-11-11. PMID:23613810. |
the influence of five polymorphisms with established effects on dopamine neurotransmission was summed using a gene score, with higher scores corresponding to higher dopaminergic neurotransmission. |
2013-11-11 |
2023-08-12 |
human |
| Satoshi Fujita, Risako Kato, Yilong Cui, Masanori Terakado, Kurando Suga, Noriaki Koshikawa, Masayuki Kobayash. Apomorphine-induced modulation of neural activities in the ventrolateral striatum of rats. Synapse (New York, N.Y.). vol 67. issue 7. 2013-11-07. PMID:23401143. |
the dopaminergic system in the ventrolateral portion of the striatum (svl), part of the basal ganglia, regulates orofacial movements; bilateral co-stimulation of both dopamine d1 -like and d2 -like receptors elicits repetitive jaw movements in rats. |
2013-11-07 |
2023-08-12 |
rat |
| Sindhu K Madathil, Saravanan S Karuppagounder, Kochupurackal P Mohanakuma. Sodium salicylate protects against rotenone-induced parkinsonism in rats. Synapse (New York, N.Y.). vol 67. issue 8. 2013-11-07. PMID:23447126. |
these animals showed significant attenuation in rotenone-induced loss in striatal dopamine levels, number of nigral dopaminergic neurons, reduced and oxidized glutathione levels, and complex i activity loss, but superoxide dismutase activity was increased further. |
2013-11-07 |
2023-08-12 |
rat |
| A Cheramy, M L Kemel, C Gauchy, J M Desce, T Galli, L Barbeito, J Glowinsk. Role of excitatory amino acids in the direct and indirect presynaptic regulation of dopamine release from nerve terminals of nigrostriatal dopaminergic neurons. Amino acids. vol 1. issue 3. 2013-11-06. PMID:24194175. |
role of excitatory amino acids in the direct and indirect presynaptic regulation of dopamine release from nerve terminals of nigrostriatal dopaminergic neurons. |
2013-11-06 |
2023-08-12 |
rat |
| Ouria Dkhissi-Benyahya, Christine Coutanson, Kenneth Knoblauch, Hasna Lahouaoui, Vincent Leviel, Catherine Rey, Mohamed Bennis, Howard M Coope. The absence of melanopsin alters retinal clock function and dopamine regulation by light. Cellular and molecular life sciences : CMLS. vol 70. issue 18. 2013-11-04. PMID:23604021. |
since melanopsin ganglion cells are known to provide a feed-back signalling pathway for photic information to dopaminergic cells, we further examined dopamine (da) synthesis in opn 4 (-/-) mice. |
2013-11-04 |
2023-08-12 |
mouse |
| Anamitra Ghosh, Hariharan Saminathan, Arthi Kanthasamy, Vellareddy Anantharam, Huajun Jin, Gautam Sondarva, Dilshan S Harischandra, Ziqing Qian, Ajay Rana, Anumantha G Kanthasam. The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. The Journal of biological chemistry. vol 288. issue 30. 2013-11-04. PMID:23754278. |
furthermore, juglone treatment in the mptp mouse model of pd suppressed pin1 levels and improved locomotor deficits, dopamine depletion, and nigral dopaminergic neuronal loss. |
2013-11-04 |
2023-08-12 |
mouse |
| Patrick J Schultheis, Sheila M Fleming, Amy K Clippinger, Jada Lewis, Taiji Tsunemi, Benoit Giasson, Dennis W Dickson, Joseph R Mazzulli, Mark E Bardgett, Kristi L Haik, Osunde Ekhator, Anil Kumar Chava, John Howard, Matt Gannon, Elizabeth Hoffman, Yinhuai Chen, Vikram Prasad, Stephen C Linn, Rafael J Tamargo, Wendy Westbroek, Ellen Sidransky, Dimitri Krainc, Gary E Shul. Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits. Human molecular genetics. vol 22. issue 10. 2013-11-01. PMID:23393156. |
there was no change in the number of dopaminergic neurons in the substantia nigra or in striatal dopamine levels in aged atp13a2(-/-) mice. |
2013-11-01 |
2023-08-12 |
mouse |
| Rita Perfeito, Teresa Cunha-Oliveira, Ana Cristina Reg. Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse. Free radical biology & medicine. vol 62. 2013-11-01. PMID:23743292. |
the selective degeneration of dopaminergic neurons suggests that dopamine itself may contribute to the neurodegenerative process in pd. |
2013-11-01 |
2023-08-12 |
Not clear |
| Yan Chen, Ying-yin Ni, Jie Liu, Jia-wei Lu, Fang Wang, Xiao-lin Wu, Ming-min Gu, Zhen-yu Lu, Zhu-gang Wang, Zhi-hua Re. Dopamine receptor 3 might be an essential molecule in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. BMC neuroscience. vol 14. 2013-11-01. PMID:23902361. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) induces parkinson's disease (pd)-like neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) via its oxidized product, 1-methyl-4-phenylpyridinium (mpp+), which is transported by the dopamine (da) transporter into da nerve terminals. |
2013-11-01 |
2023-08-12 |
mouse |
| Ting-Han Wu, Yu-Ning Lu, Chia-Lung Chuang, Chia-Lin Wu, Ann-Shyn Chiang, David E Krantz, Hui-Yun Chan. Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta neuropathologica. vol 125. issue 5. 2013-10-31. PMID:23494099. |
loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a drosophila model expressing human tau. |
2013-10-31 |
2023-08-12 |
human |