| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carla Thiciane Vasconcelos Melo, Alyne Mara Rodrigues de Carvalho, Brinell Arcanjo Moura, Caroline Porto Leite Teixeira, Leonardo Freire Vasconcelos, Mariana Lima Feitosa, Gersilene Valente de Oliveira, José Maria Barbosa-Filho, Stanley Juan Chavez Gutierrez, Marta Maria de França Fonteles, Silvânia Maria Mendes Vasconcelos, Francisca Cléa Florenço de Sous. Evidence for the involvement of the serotonergic, noradrenergic, and dopaminergic systems in the antidepressant-like action of riparin III obtained from Aniba riparia (Nees) Mez (Lauraceae) in mice. Fundamental & clinical pharmacology. vol 27. issue 1. 2013-06-25. PMID:21793900. |
in conclusion, the present study provides evidence that the antidepressant-like effect of ripiii is dependent on its interaction with the serotonergic, noradrenergic (α₁- and α₂- receptors), and dopaminergic (dopamine d₂ receptors) systems. |
2013-06-25 |
2023-08-12 |
mouse |
| Sonia Cavaliere, John M Gillespie, James J L Hodg. KCNQ channels show conserved ethanol block and function in ethanol behaviour. PloS one. vol 7. issue 11. 2013-06-24. PMID:23209695. |
acute activation of dopaminergic neurons by heat-activated trp channel or kcnq-rnai expression produced ethanol hypersensitivity, suggesting that both act via a common mechanism involving membrane depolarisation and increased dopamine signalling leading to ethanol sedation. |
2013-06-24 |
2023-08-12 |
drosophila_melanogaster |
| José Carlos Pereira, Ingrid Ramos Rocha e Silva, Márcia Pradella-Hallina. Transient Willis-Ekbom's disease (restless legs syndrome) during pregnancy may be caused by estradiol-mediated dopamine overmodulation. Medical hypotheses. vol 80. issue 2. 2013-06-24. PMID:23257652. |
dopamine is a neuroendocrine hormone that diminishes the levels of thyrotropin and consequently of thyroxine, and one of the roles of the dopaminergic system is to counteract the activity of thyroid hormones. |
2013-06-24 |
2023-08-12 |
Not clear |
| Stéphane Thobois, Eugénie Lhommée, Hélène Klinger, Claire Ardouin, Emmanuelle Schmitt, Amélie Bichon, Andrea Kistner, Anna Castrioto, Jing Xie, Valerie Fraix, Pierre Pelissier, Stephan Chabardes, Patrick Mertens, Jean-Louis Quesada, Jean-Luc Bosson, Pierre Pollak, Emmanuel Broussolle, Paul Krac. Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil. Brain : a journal of neurology. vol 136. issue Pt 5. 2013-06-24. PMID:23543483. |
to confirm our hypothesis of parkinsonian apathy being related to mesolimbic dopaminergic denervation, we performed a randomized controlled study using piribedil, a relatively selective d2/d3 dopamine agonist to treat parkinsonian apathy, using the model of postoperative apathy. |
2013-06-24 |
2023-08-12 |
Not clear |
| Mattias Rickhag, Freja Herborg Hansen, Gunnar Sørensen, Kristine Nørgaard Strandfelt, Bjørn Andresen, Kamil Gotfryd, Kenneth L Madsen, Ib Vestergaard-Klewe, Ina Ammendrup-Johnsen, Jacob Eriksen, Amy H Newman, Ernst-Martin Füchtbauer, Jesus Gomeza, David P D Woldbye, Gitta Wörtwein, Ulrik Gethe. A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter. Nature communications. vol 4. 2013-06-20. PMID:23481388. |
in cultured dopaminergic neurons and striatal slices from dopamine transporter-aaa mice, we find markedly reduced dopamine transporter surface levels and evidence for enhanced constitutive internalization. |
2013-06-20 |
2023-08-12 |
mouse |
| Jan Booij, Liesbeth Reneman, Marielle Alders, Taco W Kuijper. Increase in central striatal dopamine transporters in patients with Shwachman-Diamond syndrome: additional evidence of a brain phenotype. American journal of medical genetics. Part A. vol 161A. issue 1. 2013-06-19. PMID:23239620. |
therefore, in this study we assessed in vivo dopamine transporters (dats; a specific marker of dopaminergic cells expressed in nerve terminals) and performed structural mri in sds. |
2013-06-19 |
2023-08-12 |
Not clear |
| A Testa, R Giannuzzi, F Sollazzo, L Petrongolo, L Bernardini, S Dai. Psychiatric emergencies (part II): psychiatric disorders coexisting with organic diseases. European review for medical and pharmacological sciences. vol 17 Suppl 1. 2013-06-18. PMID:23436669. |
abuse substances have specific molecular targets and very different acute mechanisms of action, mainly involving dopaminergic and serotoninergic systems, but finally converging on the brain's reward pathways, increasing dopamine in nucleus accumbens. |
2013-06-18 |
2023-08-12 |
Not clear |
| K W Kim, J H Jhoo, S B Lee, S D Lee, T H Kim, S E Kim, Y K Kim, I-Y Yoo. Increased striatal dopamine transporter density in moderately severe old restless legs syndrome patients. European journal of neurology. vol 19. issue 9. 2013-06-17. PMID:22435397. |
dopamine dysregulation in restless legs syndrome (rls) may be varied by the severity of rls, which could contribute to the conflicting results from previous functional neuroimaging studies on the central dopaminergic neurotransmission of rls. |
2013-06-17 |
2023-08-12 |
Not clear |
| Masago Ishikawa, Mami Otaka, Yanhua H Huang, Peter A Neumann, Bradley D Winters, Anthony A Grace, Oliver M Schlüter, Yan Don. Dopamine triggers heterosynaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 16. 2013-06-17. PMID:23595734. |
in contrast, our present results demonstrate that within the parallel projections of dopaminergic and gabaergic terminals from the ventral tegmental area to the nucleus accumbens core (nacco), action-potential-activated release of dopamine heterosynaptically triggers ltd at gabaergic synapses, which is likely mediated by activating presynaptically located dopamine d1 class receptors and expressed by inhibiting presynaptic release of gaba. |
2013-06-17 |
2023-08-12 |
Not clear |
| Takashi Konishi, Satoshi Kono, Masaya Fujimoto, Tatsuhiro Terada, Kozo Matsushita, Yasuomi Ouchi, Hiroaki Miyajim. Benign hereditary chorea: dopaminergic brain imaging in patients with a novel intronic NKX2.1 gene mutation. Journal of neurology. vol 260. issue 1. 2013-06-14. PMID:22825795. |
we herein report the clinical features of six patients from a single family with a novel intronic mutation and present the dopaminergic neuronal imaging by using positron emission tomography (pet) imaging to assess the integrity of the striatal dopaminergic system using [(11)c]-cft for the presynaptic dopamine transporter function and [(11)c]-raclopride for the postsynaptic d2 receptor function. |
2013-06-14 |
2023-08-12 |
Not clear |
| Alison I Bernstein, Karen L O'Malle. MPP+-induces PUMA- and p53-dependent, but ATF3-independent cell death. Toxicology letters. vol 219. issue 2. 2013-06-14. PMID:23500530. |
parkinson's disease (pd) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (sn) and depletion of striatal dopamine (da), leading to a range of motor symptoms, including resting tremor, rigidity, bradykinesia and postural abnormalities. |
2013-06-14 |
2023-08-12 |
mouse |
| Erik B Oleson, Joseph F Chee. On the role of subsecond dopamine release in conditioned avoidance. Frontiers in neuroscience. vol 7. 2013-06-14. PMID:23759871. |
the latter observation is inconsistent with the second component of the two-factor theory of avoidance and; therefore, led us propose a new theoretical explanation of conditioned avoidance: (1) fear is initially conditioned to the warning signal and dopamine computes this fear association as a decrease in release, (2) the warning signal, now capable of producing a negative emotional state, suppresses dopamine release and behavior, (3) over repeated trials the warning signal becomes associated with safety rather than fear; dopaminergic neurons already compute safety as an increase in release and begin to encode the warning signal as the earliest predictor of safety (4) the warning signal now promotes conditioned avoidance via dopaminergic modulation of the brain's incentive-motivational circuitry. |
2013-06-14 |
2023-08-12 |
Not clear |
| Peizhou Jiang, Ming Gan, Shu-Hui C Ye. Dopamine prevents lipid peroxidation-induced accumulation of toxic α-synuclein oligomers by preserving autophagy-lysosomal function. Frontiers in cellular neuroscience. vol 7. 2013-06-12. PMID:23754979. |
the formation of lewy bodies containing α-synuclein (α-syn), prominent loss of dopaminergic neurons and dopamine (da) deficiency in substantia nigra and striatum are histopathological and biochemical hallmarks of parkinson's disease (pd). |
2013-06-12 |
2023-08-12 |
human |
| D G Machado, V B Neis, G O Balen, A Colla, M P Cunha, J B Dalmarco, M G Pizzolatti, R D Prediger, A L S Rodrigue. Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: evidence for the involvement of the dopaminergic system. Pharmacology, biochemistry, and behavior. vol 103. issue 2. 2013-06-11. PMID:22940588. |
these results indicate that the antidepressant-like effect of ursolic acid in the tst is likely mediated by an interaction with the dopaminergic system, through the activation of dopamine d(1) and d(2) receptors. |
2013-06-11 |
2023-08-12 |
mouse |
| Sharon J Lin, S Alisha Epps, Charles H West, Katherine A Boss-Williams, Jay M Weiss, David Weinshenke. Operant psychostimulant self-administration in a rat model of depression. Pharmacology, biochemistry, and behavior. vol 103. issue 2. 2013-06-11. PMID:23010383. |
we have shown previously that while rats selectively bred for depression-like phenotypes (swlo) have blunted mesolimbic dopamine (da) signaling and locomotor responses to dopaminergic drugs, they voluntarily administer excessive amounts of psychostimulants compared to normal or depression-resistant (swhi) rats in oral consumption paradigms. |
2013-06-11 |
2023-08-12 |
rat |
| Eriko Fujita-Jimbo, Zhi-Ling Yu, Hong Li, Takanori Yamagata, Masato Mori, Takashi Momoi, Mariko Y Momo. Mutation in Parkinson disease-associated, G-protein-coupled receptor 37 (GPR37/PaelR) is related to autism spectrum disorder. PloS one. vol 7. issue 12. 2013-06-11. PMID:23251443. |
gpr37 is associated with the dopamine transporter to modulate dopamine uptake, and regulates behavioral responses to dopaminergic drugs. |
2013-06-11 |
2023-08-12 |
Not clear |
| Jun-Xu Li, David A Thorn, Chunyang Ji. The GPR88 receptor agonist 2-PCCA does not alter the behavioral effects of methamphetamine in rats. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23123351. |
genetic knockout studies reveal phenotypes of increased dopamine d(2) receptor sensitivity in mice, suggesting that gpr88 receptors may be involved in the modulation of dopaminergic system. |
2013-06-10 |
2023-08-12 |
mouse |
| Guiqin Xie, Krešimir Krnjević, Jiang-Hong Y. Salsolinol modulation of dopamine neurons. Frontiers in behavioral neuroscience. vol 7. 2013-06-10. PMID:23745110. |
previous evidence obtained in vivo links salsolinol with the mesolimbic dopaminergic (da) system: salsolinol is self-administered into the posterior of the ventral tegmental area (pvta) of rats; intra-vta administration of salsolinol induces a strong conditional place preference and increases dopamine release in the nucleus accumbens (nac). |
2013-06-10 |
2023-08-12 |
human |
| Jyoti C Patel, Margaret E Ric. Monitoring axonal and somatodendritic dopamine release using fast-scan cyclic voltammetry in brain slices. Methods in molecular biology (Clifton, N.J.). vol 964. 2013-06-06. PMID:23296788. |
establishing factors that regulate dopamine release can provide novel insights into dopaminergic communication under normal conditions, as well as in animal models of disease in the brain. |
2013-06-06 |
2023-08-12 |
Not clear |
| Wei Zhang, Luigi Zecca, Belinda Wilson, Hong-Wei Ren, Yong-Jun Wang, Xiao-Min Wang, Jau-Shyong Hon. Human neuromelanin: an endogenous microglial activator for dopaminergic neuron death. Frontiers in bioscience (Elite edition). vol 5. 2013-06-05. PMID:23276965. |
using multiple primary mesencephalic cultures, we found that hnm caused dopaminergic neurodegeneration characterized by the decreased dopamine uptake and reduced numbers and shorted dendrites. |
2013-06-05 |
2023-08-12 |
human |