| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew W Rice, Rosalinda C Roberts, Miguel Melendez-Ferro, Emma Perez-Costa. Mapping dopaminergic deficiencies in the substantia nigra/ventral tegmental area in schizophrenia. Brain structure & function. vol 221. issue 1. 2016-10-14. PMID:25269834. |
these data support the existence of pathway-specific dopaminergic deficits that would affect the dopamine input to the cortex without significant neuronal loss. |
2016-10-14 |
2023-08-13 |
Not clear |
| Weibo Shi, Chunling Ma, Qian Qi, Lizhe Liu, Haitao Bi, Bin Cong, Yingmin L. The effect of different durations of morphine exposure on mesencephalic dopaminergic neurons in morphine dependent rats. Neurotoxicology. vol 51. 2016-10-12. PMID:26386147. |
thyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis, plays an important role in the survival of dopaminergic neurons. |
2016-10-12 |
2023-08-13 |
rat |
| Sarah J Stednitz, Briana Freshner, Samantha Shelton, Tori Shen, Donovan Black, Ethan Gahta. Selective toxicity of L-DOPA to dopamine transporter-expressing neurons and locomotor behavior in zebrafish larvae. Neurotoxicology and teratology. vol 52. issue Pt A. 2016-10-12. PMID:26546233. |
the primary neuropathology in pd involves the death of dopaminergic cells in the substantia nigra (sn), an anatomical region of the brain implicated in dopamine production and voluntary motor control. |
2016-10-12 |
2023-08-13 |
zebrafish |
| Sarah J Stednitz, Briana Freshner, Samantha Shelton, Tori Shen, Donovan Black, Ethan Gahta. Selective toxicity of L-DOPA to dopamine transporter-expressing neurons and locomotor behavior in zebrafish larvae. Neurotoxicology and teratology. vol 52. issue Pt A. 2016-10-12. PMID:26546233. |
increasing evidence suggests that the neurotransmitter dopamine may have a neurotoxic metabolic product (dopal) that selectively damages dopaminergic cells. |
2016-10-12 |
2023-08-13 |
zebrafish |
| M Reza Razeghinejad, M Hossein Nowroozzadeh, M Hossein Eghba. Levodopa and Other Pharmacologic Interventions in Ischemic and Traumatic Optic Neuropathies and Amblyopia. Clinical neuropharmacology. vol 39. issue 1. 2016-10-11. PMID:26757312. |
levodopa, a precursor of dopamine, can easily breach the blood-brain and blood-retinal barriers, and exerts effective dopaminergic responses in the brain and retina. |
2016-10-11 |
2023-08-13 |
Not clear |
| Milky Kohno, Erika L Nurmi, Christopher P Laughlin, Angelica M Morales, Emma H Gail, Gerhard S Hellemann, Edythe D Londo. Functional Genetic Variation in Dopamine Signaling Moderates Prefrontal Cortical Activity During Risky Decision Making. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26119471. |
for each participant, dopamine function was assessed using a gene composite score combining known functional variation across five genes involved in dopaminergic signaling: drd2, drd3, drd4, dat1, and comt. |
2016-10-06 |
2023-08-13 |
human |
| Milky Kohno, Erika L Nurmi, Christopher P Laughlin, Angelica M Morales, Emma H Gail, Gerhard S Hellemann, Edythe D Londo. Functional Genetic Variation in Dopamine Signaling Moderates Prefrontal Cortical Activity During Risky Decision Making. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26119471. |
our findings support the view that the links between dopaminergic signaling, prefrontal function, and decision making vary as a function of dopamine signaling capacity. |
2016-10-06 |
2023-08-13 |
human |
| E J Marijke Achterberg, Linda W M van Kerkhof, Michela Servadio, Maaike M H van Swieten, Danielle J Houwing, Mandy Aalderink, Nina V Driel, Viviana Trezza, Louk J M J Vanderschure. Contrasting Roles of Dopamine and Noradrenaline in the Motivational Properties of Social Play Behavior in Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26174597. |
dopaminergic neurotransmission plays a key role in incentive motivational processes, and both dopamine and noradrenaline have been implicated in the modulation of social play behavior. |
2016-10-06 |
2023-08-13 |
rat |
| Thorben Schlüter, Oliver Winz, Karsten Henkel, Thomas Eggermann, Siamak Mohammadkhani-Shali, Claudia Dietrich, Alexander Heinzel, Michel Decker, Paul Cumming, Klaus Zerres, Markus Piel, Felix M Mottaghy, Ingo Vernaleke. MAOA-VNTR polymorphism modulates context-dependent dopamine release and aggressive behavior in males. NeuroImage. vol 125. 2016-09-30. PMID:26481676. |
interestingly, the two maoa-groups showed inverse dopaminergic and behavioral reactions to the violent movie: the maoa-high group showed higher dopamine release and increased aggression after the violent movie; maoa-low subjects showed decreases in aggressive behavior and no consistent dopamine release. |
2016-09-30 |
2023-08-13 |
human |
| Miriam Kannebley Frank, Marco Tulio de Mello, Kil Sun Lee, Paulo Daubian-Nosé, Sergio Tufik, Andrea Maculano Esteve. Sleep-related movement disorder symptoms in SHR are attenuated by physical exercise and an angiotensin-converting enzyme inhibitor. Physiology & behavior. vol 154. 2016-09-30. PMID:26650246. |
dopaminergic receptors, dopamine transporter and tyrosine hydroxylase levels at the striatum were evaluated by western blotting. |
2016-09-30 |
2023-08-13 |
rat |
| William C Buchta, Arthur C Riege. Chronic cocaine disrupts mesocortical learning mechanisms. Brain research. vol 1628. issue Pt A. 2016-09-27. PMID:25704202. |
in this review, we posit that a pool of extrasynaptic dopaminergic d1-like receptors activated in response to dopamine neuron burst firing serve to enable synaptic plasticity in the prefrontal cortex in response to rewards and their cues. |
2016-09-27 |
2023-08-13 |
human |
| L L Furlanetti, V A Coenen, M D Döbröss. Ventral tegmental area dopaminergic lesion-induced depressive phenotype in the rat is reversed by deep brain stimulation of the medial forebrain bundle. Behavioural brain research. vol 299. 2016-09-27. PMID:26657994. |
response to mfb-dbs varied according to (i) the degree of dopaminergic depletion: animals with severe mesocorticolimbic dopamine depletion did not, whilst those with mild dopamine loss responded well to stimulation; (ii) environmental conditions and the nature of the behavioral tests, e.g., stressful vs non-stressful situations. |
2016-09-27 |
2023-08-13 |
rat |
| Joel A Morales-Rosado, Margot A Cousin, Jon O Ebbert, Eric W Kle. A Critical Review of Repurposing Apomorphine for Smoking Cessation. Assay and drug development technologies. vol 13. issue 10. 2016-09-26. PMID:26690764. |
previously described in the literature as a non-specific dopamine agonist effective in treating parkinson's disease and erectile dysfunction, apo's dopaminergic targeting activity may be effective in counteracting the modified response arising from tobacco use. |
2016-09-26 |
2023-08-13 |
Not clear |
| Annmarie Ramkissoon, Peter G Well. Methamphetamine oxidative stress, neurotoxicity, and functional deficits are modulated by nuclear factor-E2-related factor 2. Free radical biology & medicine. vol 89. 2016-09-22. PMID:26427884. |
multiple-day dosing with meth enhanced dna oxidation and decreased tyrosine hydroxylase and dopamine transporter staining in the striatum, indicating dopaminergic nerve terminal toxicity, which was more severe in -/- mice, as were deficits in motor coordination and olfactory discrimination. |
2016-09-22 |
2023-08-13 |
mouse |
| Juliane Mehlan, Hans Brosig, Oliver Schmitt, Eilhard Mix, Andreas Wree, Alexander Hawlitschk. Intrastriatal injection of botulinum neurotoxin-A is not cytotoxic in rat brain - A histological and stereological analysis. Brain research. vol 1630. 2016-09-19. PMID:26562665. |
parkinson's disease (pd) is caused by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta, resulting in a deficiency of dopamine in the striatum and an increased release of acetylcholine by tonically active interneurons. |
2016-09-19 |
2023-08-13 |
rat |
| J Belin, J L Houéto, T Constans, C Hommet, B de Toffol, K Mondo. [Geriatric particularities of Parkinson's disease: Clinical and therapeutic aspects]. Revue neurologique. vol 171. issue 12. 2016-09-19. PMID:26573332. |
although historically pd has been characterized by the presence of progressive dopaminergic neuronal loss of the substantia nigra, the disease process also involves neurotransmitters other that dopamine and regions of the nervous system outside the basal ganglia. |
2016-09-19 |
2023-08-13 |
human |
| Steven Tran, Arrujyan Muraleetharan, Niveen Fulcher, Diptendu Chatterjee, Robert Gerla. MK-801 increases locomotor activity in a context-dependent manner in zebrafish. Behavioural brain research. vol 296. 2016-09-15. PMID:26318934. |
in addition, we examine the potential role of the dopaminergic system in mediating mk-801's locomotor stimulant effect by quantifying the levels of dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (dopac) in the brains of zebrafish following a 30 min exposure to 10 μm of mk-801 (the dose found to induce the largest increase in locomotor activity). |
2016-09-15 |
2023-08-13 |
zebrafish |
| J Kregiel, J Golebiowska, P Popik, R Rygul. Dopamine induces an optimism bias in rats-Pharmacological proof for the translational validity of the ambiguous-cue interpretation test. Behavioural brain research. vol 297. 2016-09-15. PMID:26462571. |
to test whether an 'optimistic' bias is also mediated by dopamine in animals, first, two groups of rats received either a dopaminergic precursor, l-dopa, or a d2 receptor antagonist, haloperidol, and were subsequently tested using the ambiguous-cue interpretation (aci) paradigm. |
2016-09-15 |
2023-08-13 |
human |
| Richard M Zweig, Elizabeth A Disbrow, Vijayakumar Javalka. Cognitive and Psychiatric Disturbances in Parkinsonian Syndromes. Neurologic clinics. vol 34. issue 1. 2016-09-15. PMID:26614001. |
treatment with dopaminergic medications, particularly dopamine agonists, has been associated with hallucinations and impulse control disorder. |
2016-09-15 |
2023-08-13 |
Not clear |
| Carmen Cavada Martíne. [THE THALAMIC DOPAMINERGIC SYSTEM. A NOVEL SYSTEM IN THE PRIMATE BRAIN]. Anales de la Real Academia Nacional de Medicina. vol 131. issue 1. 2016-09-15. PMID:27386678. |
the human and macaque monkey thalamus receives an abundant dopamine innervation, as revealed by immunolabeling of axons for molecules specific for the dopaminergic phenotype. |
2016-09-15 |
2023-08-13 |
human |