| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elina Jaakkola, Juho Joutsa, Valtteri Kaasine. Predictors of normal and abnormal outcome in clinical brain dopamine transporter imaging. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 3. 2016-12-13. PMID:26676600. |
brain dopamine transporter (dat) imaging with [(123)i]fp-cit spect can be used to evaluate the integrity of the mesostriatal dopaminergic system in patients with clinically uncertain parkinsonism. |
2016-12-13 |
2023-08-13 |
Not clear |
| Pedro Barroso-Chinea, Ignacio Cruz-Muros, Domingo Afonso-Oramas, Javier Castro-Hernández, Josmar Salas-Hernández, Abdelwahed Chtarto, Diego Luis-Ravelo, Marie Humbert-Claude, Liliane Tenenbaum, Tomás González-Hernánde. Long-term controlled GDNF over-expression reduces dopamine transporter activity without affecting tyrosine hydroxylase expression in the rat mesostriatal system. Neurobiology of disease. vol 88. 2016-12-13. PMID:26777664. |
the dopamine (da) transporter (dat) is a plasma membrane glycoprotein expressed in dopaminergic (da-) cells that takes back da into presynaptic neurons after its release. |
2016-12-13 |
2023-08-13 |
human |
| Sandra Felix, Stephane Thobois, Laure Peter-Dere. Rapid eye movement sleep behaviour disorder symptomatic of a brain stem cavernoma. Journal of sleep research. vol 25. issue 2. 2016-12-13. PMID:26780965. |
dopamine transporter imaging [123i-fp-cit single photon emission computed tomography (spect)] did not find any presynaptic dopaminergic pathways degeneration. |
2016-12-13 |
2023-08-13 |
Not clear |
| Ashley N Fricks-Gleason, Christopher L German, Amanda J Hoonakker, Danielle M Friend, Kamala K Ganesh, Aaron S Carver, Glen R Hanson, Annette E Fleckenstein, Kristen A Keef. An acute, epitope-specific modification in the dopamine transporter associated with methamphetamine-induced neurotoxicity. Synapse (New York, N.Y.). vol 70. issue 4. 2016-12-13. PMID:26799527. |
preclinical studies demonstrate that repeated, high-dose methamphetamine administrations rapidly decrease plasmalemmal dopamine uptake, which may contribute to aberrant dopamine accumulation, reactive species generation, and long-term dopaminergic deficits. |
2016-12-13 |
2023-08-13 |
Not clear |
| Ludovico Arcuri, Riccardo Viaro, Simone Bido, Francesco Longo, Mariangela Calcagno, Pierre-Olivier Fernagut, Nurulain T Zaveri, Girolamo Calò, Erwan Bezard, Michele Morar. Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease. Neurobiology of disease. vol 89. 2016-12-13. PMID:26804029. |
sb-612111, given 4 days after mptp treatment to mimic the clinical condition, prevented the loss of nigral dopamine neurons and striatal dopaminergic terminals caused by subacute mptp. |
2016-12-13 |
2023-08-13 |
mouse |
| Selvaraju Meenakshi, Shanmugam Umayaparvathi, Ravichandran Saravanan, Thamilarasan Manivasagam, Thangavel Balasubramania. Neuroprotective effect of fucoidan from Turbinaria decurrens in MPTP intoxicated Parkinsonic mice. International journal of biological macromolecules. vol 86. 2016-12-13. PMID:26828289. |
the increase is greater than the content of dopamine and dopac, which may be explained that the dopaminergic terminals are more sensitive to mptp toxicity and therefore are more severely damaged than the dopaminergic cell bodies. |
2016-12-13 |
2023-08-13 |
mouse |
| K Botsakis, S Theodoritsi, K Grintzalis, F Angelatou, I Antonopoulos, C D Georgiou, M Margarity, N A Matsokis, N T Panagopoulo. 17β-Estradiol/N-acetylcysteine interaction enhances the neuroprotective effect on dopaminergic neurons in the weaver model of dopamine deficiency. Neuroscience. vol 320. 2016-12-13. PMID:26852701. |
17β-estradiol/n-acetylcysteine interaction enhances the neuroprotective effect on dopaminergic neurons in the weaver model of dopamine deficiency. |
2016-12-13 |
2023-08-13 |
mouse |
| Kohei Takahashi, Osamu Nakagawasai, Wataru Nemoto, Takeharu Nakajima, Yuichiro Arai, Tadashi Hisamitsu, Koichi Tan-N. Alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system. Psychopharmacology. vol 233. issue 7. 2016-12-13. PMID:26856855. |
alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system. |
2016-12-13 |
2023-08-13 |
mouse |
| Kyoji Okita, Dara G Ghahremani, Doris E Payer, Chelsea L Robertson, Andy C Dean, Mark A Mandelkern, Edythe D Londo. Emotion dysregulation and amygdala dopamine D2-type receptor availability in methamphetamine users. Drug and alcohol dependence. vol 161. 2016-12-13. PMID:26880595. |
although the amygdala has an important role in emotion processing and receives dopaminergic innervation, little is known about how dopamine transmission in this region contributes to emotion regulation. |
2016-12-13 |
2023-08-13 |
human |
| Cody A Siciliano, Erin S Calipari, Jordan T Yorgason, David M Lovinger, Yolanda Mateo, Vanessa A Jimenez, Christa M Helms, Kathleen A Grant, Sara R Jone. Increased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaques. Psychopharmacology. vol 233. issue 8. 2016-12-13. PMID:26892380. |
hypofunction of striatal dopamine neurotransmission, or hypodopaminergia, is a consequence of excessive ethanol use and is hypothesized to be a critical component of alcoholism, driving alcohol intake in an attempt to restore dopamine levels; however, the neurochemical mechanisms involved in these dopaminergic deficiencies are not fully understood. |
2016-12-13 |
2023-08-13 |
Not clear |
| Pedro Espinosa, Roxana A Silva, Nicole K Sanguinetti, Francisca C Venegas, Raul Riquelme, Luis F González, Gonzalo Cruz, Georgina M Renard, Pablo R Moya, Ramón Sotomayor-Zárat. Programming of Dopaminergic Neurons by Neonatal Sex Hormone Exposure: Effects on Dopamine Content and Tyrosine Hydroxylase Expression in Adult Male Rats. Neural plasticity. vol 2016. 2016-12-13. PMID:26904299. |
programming of dopaminergic neurons by neonatal sex hormone exposure: effects on dopamine content and tyrosine hydroxylase expression in adult male rats. |
2016-12-13 |
2023-08-13 |
rat |
| Mauro Pettorruso, Alfonso Fasano, Luisa De Risio, Lucia Ricciardi, Marco Di Nicola, Giovanni Martinotti, Luigi Janiri, Anna Rita Bentivogli. Punding in non-demented Parkinson's disease patients: Relationship with psychiatric and addiction spectrum comorbidity. Journal of the neurological sciences. vol 362. 2016-12-13. PMID:26944176. |
punding is a stereotyped behavior characterized by an intense fascination with a complex, excessive, non-goal oriented, repetitive activity, associated with dopaminergic replacement therapy (drt) in patients affected by parkinson's disease (pd) and with dopamine agonists in several conditions. |
2016-12-13 |
2023-08-13 |
Not clear |
| Juan Camilo Jurado-Coronel, Marco Avila-Rodriguez, Francisco Capani, Janneth Gonzalez, Valentina Echeverria Moran, George E Barret. Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease. Current pharmaceutical design. vol 22. issue 10. 2016-12-13. PMID:26972289. |
parkinson's disease (pd) is a relatively common disorder of the central nervous system (cns), whose etiology is characterized by a selective and progressive degeneration of dopaminergic neurons, and the presence of lewy bodies in the pars compacta of the substantia nigra, and gaping dopamine depletion in the striatum. |
2016-12-13 |
2023-08-13 |
Not clear |
| Motokazu Uchigashima, Toshihisa Ohtsuka, Kazuto Kobayashi, Masahiko Watanab. Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 15. 2016-12-13. PMID:27035941. |
dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and gabaergic postsynaptic structures. |
2016-12-13 |
2023-08-13 |
Not clear |
| Motokazu Uchigashima, Toshihisa Ohtsuka, Kazuto Kobayashi, Masahiko Watanab. Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 15. 2016-12-13. PMID:27035941. |
because dopamine receptors are widely expressed away from dopamine synapses, it remains unclear how dopamine synapses are involved in dopaminergic transmission. |
2016-12-13 |
2023-08-13 |
Not clear |
| Motokazu Uchigashima, Toshihisa Ohtsuka, Kazuto Kobayashi, Masahiko Watanab. Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 15. 2016-12-13. PMID:27035941. |
here we demonstrate that dopamine synapses are contacts formed between dopaminergic presynaptic and gabaergic postsynaptic structures. |
2016-12-13 |
2023-08-13 |
Not clear |
| Motokazu Uchigashima, Toshihisa Ohtsuka, Kazuto Kobayashi, Masahiko Watanab. Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 15. 2016-12-13. PMID:27035941. |
considering that msn dendrites are preferential targets of dopamine synapses and express high levels of dopamine receptors, dopamine synapse formation may serve to increase the specificity and potency of dopaminergic modulation of striatal outputs by anchoring dopamine release sites to dopamine-sensing targets. |
2016-12-13 |
2023-08-13 |
Not clear |
| Arathy S Kumar, Sankar Jagadeeshan, Anirudh Subramanian, Saravana Babu Chidambaram, Rohan Prasad Surabhi, Mahak Singhal, Hemadev Bhoopalan, Sathiya Sekar, Ravi Shankar Pitani, Prathiba Duvuru, Ganesh Venkatraman, Suresh K Rayal. Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor. The Journal of biological chemistry. vol 291. issue 23. 2016-12-13. PMID:27044752. |
parkinson disease (pd) is a neurodegenerative disorder with loss of dopaminergic neurons of the brain, which results in insufficient synthesis and action of dopamine. |
2016-12-13 |
2023-08-13 |
mouse |
| Dimitri Ryczko, Jackson J Cone, Michael H Alpert, Laurent Goetz, François Auclair, Catherine Dubé, Martin Parent, Mitchell F Roitman, Simon Alford, Réjean Dubu. A descending dopamine pathway conserved from basal vertebrates to mammals. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 17. 2016-12-13. PMID:27071118. |
stimulation of the dopaminergic region evoked dopamine release in brainstem locomotor networks and concurrent reticulospinal activity. |
2016-12-13 |
2023-08-13 |
human |
| Dimitri Ryczko, Jackson J Cone, Michael H Alpert, Laurent Goetz, François Auclair, Catherine Dubé, Martin Parent, Mitchell F Roitman, Simon Alford, Réjean Dubu. A descending dopamine pathway conserved from basal vertebrates to mammals. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 17. 2016-12-13. PMID:27071118. |
in rats, some dopamine neurons projecting to the striatum also innervated the pedunculopontine nucleus, a known locomotor center, and stimulation of the dopaminergic region evoked pedunculopontine dopamine release in vivo. |
2016-12-13 |
2023-08-13 |
human |