| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Brown, D Bullock, S Grossber. How the basal ganglia use parallel excitatory and inhibitory learning pathways to selectively respond to unexpected rewarding cues. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 23. 1999-12-17. PMID:10575046. |
after classically conditioned learning, dopaminergic cells in the substantia nigra pars compacta (snc) respond immediately to unexpected conditioned stimuli (cs) but omit formerly seen responses to expected unconditioned stimuli, notably rewards. |
1999-12-17 |
2023-08-12 |
Not clear |
| Y Kang, T Futam. Arrhythmic firing in dopamine neurons of rat substantia nigra evoked by activation of subthalamic neurons. Journal of neurophysiology. vol 82. issue 3. 1999-11-01. PMID:10482778. |
intracellular recordings were made from dopaminergic neurons of the rat substantia nigra compacta (snc) in in vitro slice preparations to study the synaptic influence from the subthalamic nucleus (sth). |
1999-11-01 |
2023-08-12 |
rat |
| S J Lokwan, P G Overton, M S Berry, D Clar. Stimulation of the pedunculopontine tegmental nucleus in the rat produces burst firing in A9 dopaminergic neurons. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392847. |
finally, although there was no difference in the distribution within the substantia nigra pars compacta of cells which exhibited time-locked bursting and those which did not, stimulation-induced bursts were elicited more frequently in dopaminergic neurons which were classified as "bursting" on the basis of their basal activity. |
1999-10-06 |
2023-08-12 |
rat |
| Y Iribe, K Moore, K C Pang, J M Teppe. Subthalamic stimulation-induced synaptic responses in substantia nigra pars compacta dopaminergic neurons in vitro. Journal of neurophysiology. vol 82. issue 2. 1999-09-23. PMID:10444687. |
subthalamic stimulation-induced synaptic responses in substantia nigra pars compacta dopaminergic neurons in vitro. |
1999-09-23 |
2023-08-12 |
Not clear |
| Y Iribe, K Moore, K C Pang, J M Teppe. Subthalamic stimulation-induced synaptic responses in substantia nigra pars compacta dopaminergic neurons in vitro. Journal of neurophysiology. vol 82. issue 2. 1999-09-23. PMID:10444687. |
synaptic potentials were recorded intracellularly from substantia nigra pars compacta dopaminergic neurons in parasagittal slices in response to stimulation of the stn. |
1999-09-23 |
2023-08-12 |
Not clear |
| Y Iribe, K Moore, K C Pang, J M Teppe. Subthalamic stimulation-induced synaptic responses in substantia nigra pars compacta dopaminergic neurons in vitro. Journal of neurophysiology. vol 82. issue 2. 1999-09-23. PMID:10444687. |
these data indicate that electrical stimulation of the stn elicits a mixed epsp-ipsp in nigral dopaminergic neurons due to the coactivation of an excitatory monosynaptic and an inhibitory polysynaptic connection between the stn and the dopaminergic neurons of substantia nigra pars compacta. |
1999-09-23 |
2023-08-12 |
Not clear |
| V M Goettl, T A Wemlinger, A M Duchemin, N H Neff, M Hadjiconstantino. GM1 ganglioside restores dopaminergic neurochemical and morphological markers in aged rats. Neuroscience. vol 92. issue 3. 1999-09-09. PMID:10426539. |
gm1 corrected the morphology of dopaminergic neurons in the substantia nigra pars compacta and partially improved it in the ventral tegmental area. |
1999-09-09 |
2023-08-12 |
rat |
| Q Chen, A H Andersen, Z Zhang, A Ovadia, W A Cass, D M Gash, M J Aviso. Functional MRI of basal ganglia responsiveness to levodopa in parkinsonian rhesus monkeys. Experimental neurology. vol 158. issue 1. 1999-09-09. PMID:10448418. |
responses consistent with increased neuronal activity were seen in areas whose normal dopaminergic input from the substantia nigra pars compacta had been ablated by mptp. |
1999-09-09 |
2023-08-12 |
monkey |
| N Soonawala, K P Bhatia, J H Yeung, N P Quinn, C D Marsde. Idiopathic blepharospasm does not lead to a parkinsonian syndrome: results of a questionnaire-based follow-up study. Journal of neurology. vol 246. issue 4. 1999-09-08. PMID:10367696. |
it has been suggested that a lesion in the dopaminergic neurons of the substantia nigra pars compacta combined with eye irritation is involved in the pathophysiology of idiopathic blepharospasm. |
1999-09-08 |
2023-08-12 |
Not clear |
| R L Klein, R K McNamara, M A King, R H Lenox, N Muzyczka, E M Meye. Generation of aberrant sprouting in the adult rat brain by GAP-43 somatic gene transfer. Brain research. vol 832. issue 1-2. 1999-08-18. PMID:10375659. |
single injections of raav into the substantia nigra pars compacta (snc) transduced both dopaminergic and non-dopaminergic neurons stably for the 3-month duration of the study. |
1999-08-18 |
2023-08-12 |
rat |
| H Slovin, M Abeles, E Vaadia, I Haalman, Y Prut, H Bergma. Frontal cognitive impairments and saccadic deficits in low-dose MPTP-treated monkeys. Journal of neurophysiology. vol 81. issue 2. 1999-08-17. PMID:10036286. |
tyrosine hydroxylase immunohistochemistry showed moderate ( approximately 70-80%) reduction in the number of dopaminergic neurons in the substantia nigra pars compacta after mptp treatment. |
1999-08-17 |
2023-08-12 |
monkey |
| P Foley, P Riedere. Pathogenesis and preclinical course of Parkinson's disease. Journal of neural transmission. Supplementum. vol 56. 1999-08-02. PMID:10370902. |
the progressive and irreversible degeneration of dopaminergic neurons projecting from the substantia nigra pars compacta (snc) to the striatum and the presence of snc lewy bodies are regarded as the essential pathological bases of ip, but neither the initiator(s) nor the nature of the degeneration have been determined, nor its relationship with degenerative changes in other parts of the ip brain. |
1999-08-02 |
2023-08-12 |
Not clear |
| A Guyon, S Laurent, D Paupardin-Tritsch, J Rossier, D Eugèn. Incremental conductance levels of GABAA receptors in dopaminergic neurones of the rat substantia nigra pars compacta. The Journal of physiology. vol 516 ( Pt 3). 1999-07-29. PMID:10200421. |
incremental conductance levels of gabaa receptors in dopaminergic neurones of the rat substantia nigra pars compacta. |
1999-07-29 |
2023-08-12 |
rat |
| A Guyon, S Laurent, D Paupardin-Tritsch, J Rossier, D Eugèn. Incremental conductance levels of GABAA receptors in dopaminergic neurones of the rat substantia nigra pars compacta. The Journal of physiology. vol 516 ( Pt 3). 1999-07-29. PMID:10200421. |
molecular and biophysical properties of gabaa receptors of dopaminergic (da) neurones of the pars compacta of the rat substantia nigra were studied in slices and after acute dissociation. |
1999-07-29 |
2023-08-12 |
rat |
| M Meyer, J Zimmer, R W Seiler, H R Widme. GDNF increases the density of cells containing calbindin but not of cells containing calretinin in cultured rat and human fetal nigral tissue. Cell transplantation. vol 8. issue 1. 1999-07-15. PMID:10338273. |
among the dopaminergic neurons in substantia nigra pars compacta and in the ventral tegmental area, subpopulations express the calcium-binding proteins calbindin (cb) and calretinin (cr), and the cb-containing neurons are supposed to be less prone to degeneration in parkinson's disease. |
1999-07-15 |
2023-08-12 |
human |
| C A Paladini, P Celada, J M Teppe. Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199614. |
these data demonstrate that dopaminergic neurons of the substantia nigra pars compacta are inhibited by electrical stimulation of striatum, globus pallidus, and the projection neurons of substantia nigra pars reticulata in vivo. |
1999-07-07 |
2023-08-12 |
rat |
| A C Kuhlmann, T R Guilart. Regional and temporal expression of the peripheral benzodiazepine receptor in MPTP neurotoxicity. Toxicological sciences : an official journal of the Society of Toxicology. vol 48. issue 1. 1999-06-18. PMID:10330690. |
tyrosine hydroxylase (th) immunohistochemistry demonstrated dose-dependent reductions of dopaminergic neurons in the substantia nigra pars compacta, with a 67% loss measured 7 days after treatment with 80 mg/kg mptp. |
1999-06-18 |
2023-08-12 |
Not clear |
| K Parain, M G Murer, Q Yan, B Faucheux, Y Agid, E Hirsch, R Raisman-Vozar. Reduced expression of brain-derived neurotrophic factor protein in Parkinson's disease substantia nigra. Neuroreport. vol 10. issue 3. 1999-06-10. PMID:10208589. |
in control subjects, bdnf was expressed in all mesencephalic regions containing dopaminergic neurons, and in the substantia nigra pars compacta (snpc) 65% of the melanized neurons expressed bdnf. |
1999-06-10 |
2023-08-12 |
human |
| C W Olanow, W G Tatto. Etiology and pathogenesis of Parkinson's disease. Annual review of neuroscience. vol 22. 1999-06-04. PMID:10202534. |
pathological features include degeneration of dopaminergic neurons in the substantia nigra pars compacta coupled with intracytoplasmic inclusions known as lewy bodies. |
1999-06-04 |
2023-08-12 |
Not clear |
| E Bezard, C Imbert, C E Gros. Experimental models of Parkinson's disease: from the static to the dynamic. Reviews in the neurosciences. vol 9. issue 2. 1999-05-21. PMID:9711900. |
the experimental models of parkinson's disease (pd) available today can be divided into two categories according to the mode of action of the compound used: transient pharmacological impairment of dopaminergic transmission along the nigrostriatal pathway or selective destruction by a neurotoxic agent of the dopaminergic neurons of the substantia nigra pars compacta. |
1999-05-21 |
2023-08-12 |
human |