| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Savel'e. Effects of local infusions of apomorphine on the extracellular citrulline level in the striatum: Involvement of D1 and D2 dopamine receptors. Neuroscience and behavioral physiology. vol 36. issue 9. 2007-03-13. PMID:17024340. |
these data suggest that the increase in extracellular citrulline in the striatum induced by dopaminergic stimulation results from local increases in no synthase activity and that this effect involves d2, but not d1 dopamine receptors. |
2007-03-13 |
2023-08-12 |
rat |
| Marek Ceiślak, Michał Komoszyńsk. [Is the inhibition of adenosine A(2A) receptors an efficient way of Parkinson's disease treatment?]. Neurologia i neurochirurgia polska. vol 40. issue 3. 2007-02-20. PMID:16794962. |
co-localization of a(2a) and dopaminergic d2 receptors in the striatum creates a milieu for an antagonistic interaction between adenosine and dopamine. |
2007-02-20 |
2023-08-12 |
Not clear |
| Michelle J Porritt, Ann E Kingsbury, Andrew J Hughes, David W Howell. Striatal dopaminergic neurons are lost with Parkinson's disease progression. Movement disorders : official journal of the Movement Disorder Society. vol 21. issue 12. 2007-02-20. PMID:17029264. |
increased numbers of dopaminergic neurons are described in the striatum of patients with parkinson's disease. |
2007-02-20 |
2023-08-12 |
Not clear |
| b' Davide Quarta, Francisco Ciruela, Kshitij Patkar, Janusz Borycz, Marcello Solinas, Carme Lluis, Rafael Franco, Roy A Wise, Steven R Goldberg, Bruce T Hope, Amina S Woods, Sergi Ferr\\xc3\\xa. Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 1. 2007-02-09. PMID:16710311.' |
in the striatum, dopamine and acetylcholine (ach) modulate dopamine release by acting, respectively, on dopamine d(2) autoreceptors and nicotinic ach (nach) heteroreceptors localized on dopaminergic nerve terminals. |
2007-02-09 |
2023-08-12 |
rat |
| Amit Saraf, David M Virshup, Stefan Strac. Differential expression of the B'beta regulatory subunit of protein phosphatase 2A modulates tyrosine hydroxylase phosphorylation and catecholamine synthesis. The Journal of biological chemistry. vol 282. issue 1. 2007-02-08. PMID:17085438. |
whereas b'beta was highly expressed in dopaminergic cell bodies in the substantia nigra, the pp2a regulatory subunit was excluded from th-positive terminal fields in the striatum and failed to colocalize with presynaptic markers in general. |
2007-02-08 |
2023-08-12 |
rat |
| Philippe Huot, Martin Lévesque, André Paren. The fate of striatal dopaminergic neurons in Parkinson's disease and Huntington's chorea. Brain : a journal of neurology. vol 130. issue Pt 1. 2007-02-01. PMID:17142832. |
the striatum harbours a population of dopaminergic neurons that is thought to act as a local source of dopamine (da). |
2007-02-01 |
2023-08-12 |
human |
| Yasunari Sakai, Hisanobu Oda, Daisuke Yoshimura, Masato Furuichi, Dongchon Kang, Shigenori Iwai, Toshiro Hara, Yusaku Nakabepp. The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal. Journal of molecular medicine (Berlin, Germany). vol 84. issue 8. 2007-01-26. PMID:16607562. |
furthermore, mth1 suppresses the transient increase in 8-oxoguanine in mitochondrial dna in the dopaminergic nerve terminals in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration, and it protects the nerve terminals. |
2007-01-26 |
2023-08-12 |
mouse |
| Richard L Saint Marie, Alaina C Neary, Jody M Shoemaker, Neal R Swerdlo. The effects of apomorphine and D-amphetamine on striatal c-Fos expression in Sprague-Dawley and Long Evans rats and their F1 progeny. Brain research. vol 1119. issue 1. 2007-01-26. PMID:16979142. |
here we examined systemic apo (0.5 mg/kg) and amph (4.5 mg/kg) modulation of neural activity in four regions of the striatum suspected to be involved in the dopaminergic regulation of ppi - dorsolateral (dlcpu) and medial (mcpu) caudate/putamen and core (nacc) and medial shell (nacms) regions of nucleus accumbens - under conditions that mimicked those used to assess ppi. |
2007-01-26 |
2023-08-12 |
rat |
| Elena Gonzalez-Rey, Alejo Chorny, Amelia Fernandez-Martin, Nieves Varela, Mario Delgad. Vasoactive intestinal peptide family as a therapeutic target for Parkinson's disease. Expert opinion on therapeutic targets. vol 9. issue 5. 2007-01-25. PMID:16185148. |
parkinson's disease (pd) is a common neurodegenerative disorder with no effective protective treatment, characterised by a massive degeneration of dopaminergic neurons in the substantia nigra and the subsequent loss of their projecting nerve fibres in the striatum. |
2007-01-25 |
2023-08-12 |
Not clear |
| Ken-ichi Tanaka, Norio Ogawa, Masato Asanum. Molecular basis of 6-hydroxydopamine-induced caspase activations due to increases in oxidative stress in the mouse striatum. Neuroscience letters. vol 410. issue 2. 2007-01-23. PMID:17092650. |
in conclusion, 6-ohda-induced dopaminergic dysfunction is mainly due to caspase activations by increases in oxidative stress in the mouse striatum. |
2007-01-23 |
2023-08-12 |
mouse |
| Isabel Lastres-Becker, Javier Fernández-Rui. An overview of Parkinson's disease and the cannabinoid system and possible benefits of cannabinoid-based treatments. Current medicinal chemistry. vol 13. issue 30. 2007-01-23. PMID:17168732. |
pd is characterized by degeneration of the pigmented neuromelanin bearing cells of the pars compacta of the substantia nigra that leads to a severe dopaminergic denervation of the striatum. |
2007-01-23 |
2023-08-12 |
Not clear |
| Kazuya Kannari, Huo Shen, Akira Arai, Masahiko Tomiyama, Masayuki Bab. Reuptake of L-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters. Neuroscience letters. vol 402. issue 1-2. 2007-01-16. PMID:16626862. |
reuptake of l-dopa-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters. |
2007-01-16 |
2023-08-12 |
rat |
| Karen L Anderson, Yossef Itzha. Methamphetamine-induced selective dopaminergic neurotoxicity is accompanied by an increase in striatal nitrate in the mouse. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105919. |
the concentration of nitrate in the striatum was increased by about two-fold after meth administration; however, no changes in nitrate concentration were detected in other brain regions that endured dopaminergic neurotoxicity. |
2007-01-10 |
2023-08-12 |
mouse |
| Karen L Anderson, Yossef Itzha. Methamphetamine-induced selective dopaminergic neurotoxicity is accompanied by an increase in striatal nitrate in the mouse. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105919. |
these findings suggest that (a) a neurotoxic regimen of meth produces selective increase in no in the striatum, which may generate toxic species such as peroxynitrite, and (b) toxins other than no-related derivatives may mediate dopaminergic neurotoxicity in the amygdala and frontal cortex. |
2007-01-10 |
2023-08-12 |
mouse |
| Erwin Lauwers, Dirk Bequé, Koen Van Laere, Johan Nuyts, Guy Bormans, Luc Mortelmans, Cindy Casteels, Linda Vercammen, Olivier Bockstael, Bart Nuttin, Zeger Debyser, Veerle Baekeland. Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression. Neurobiology of aging. vol 28. issue 2. 2007-01-09. PMID:16423428. |
there was a strong correlation between the reduction of dopaminergic neurons in the substantia nigra and the reduction of dopamine transporter binding in the striatum. |
2007-01-09 |
2023-08-12 |
rat |
| Michel Cyr, Tatyana D Sotnikova, Raul R Gainetdinov, Marc G Caro. Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 14. 2007-01-01. PMID:17065224. |
however, the mutant huntingtin protein aggregated much earlier and to a greater extent in the striatum and other dopaminergic brain regions in the hyperdopaminergic mouse model of hd. |
2007-01-01 |
2023-08-12 |
mouse |
| Maria Lindskog, MyungSook Kim, Martin A Wikström, Kim T Blackwell, Jeanette Hellgren Kotalesk. Transient calcium and dopamine increase PKA activity and DARPP-32 phosphorylation. PLoS computational biology. vol 2. issue 9. 2006-12-22. PMID:16965177. |
reinforcement learning theorizes that strengthening of synaptic connections in medium spiny neurons of the striatum occurs when glutamatergic input (from cortex) and dopaminergic input (from substantia nigra) are received simultaneously. |
2006-12-22 |
2023-08-12 |
Not clear |
| Leonid Yavich, Pekka Jäkälä, Heikki Tanil. Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in alpha-synuclein knockout and A30P transgenic mice. Journal of neurochemistry. vol 99. issue 3. 2006-12-20. PMID:16824047. |
the effects are essentially the same as previously reported for dopaminergic terminals in the striatum, indicating that the important role of alpha-synuclein in neurotransmitter mobilization is not limited to dopaminergic terminals. |
2006-12-20 |
2023-08-12 |
mouse |
| Jörn Schmaljohann, Daniela Gündisch, Martina Minnerop, Jan Bucerius, Alexius Joe, Michael Reinhardt, Stefan Guhlke, Hans-Jürgen Biersack, Ullrich Wüllne. In vitro evaluation of nicotinic acetylcholine receptors with 2-[18F]F-A85380 in Parkinson's disease. Nuclear medicine and biology. vol 33. issue 3. 2006-12-18. PMID:16631078. |
2-[18f]f-a85380 binding was significantly reduced in the striatum ipsilateral to the lesion side (to 64% of the contralateral side), indicating that a fraction of alpha4beta2 nachrs is located on dopaminergic terminals, whereas another fraction resides on striatal interneurons or cortical afferents. |
2006-12-18 |
2023-08-12 |
human |
| Toshiyuki Kawasaki, Kotaro Ishihara, Yukio Ago, Shigeo Nakamura, Soichi Itoh, Akemichi Baba, Toshio Matsud. Protective effect of the radical scavenger edaravone against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum. European journal of pharmacology. vol 542. issue 1-3. 2006-12-14. PMID:16784740. |
protective effect of the radical scavenger edaravone against methamphetamine-induced dopaminergic neurotoxicity in mouse striatum. |
2006-12-14 |
2023-08-12 |
mouse |