| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Osamu Kitamura, Itsuo Tokunaga, Takako Gotohda, Shin-ichi Kub. Immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users. International journal of legal medicine. vol 121. issue 3. 2007-07-31. PMID:16622715. |
these findings might indicate that dopaminergic terminal degeneration is induced in the striatum of some meth abusers. |
2007-07-31 |
2023-08-12 |
human |
| R E Nordquist, P Voorn, J G de Mooij-van Malsen, R N J M A Joosten, C M A Pennartz, L J M J Vanderschure. Augmented reinforcer value and accelerated habit formation after repeated amphetamine treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 8. 2007-07-30. PMID:17275266. |
augmented dopaminergic neurotransmission in the striatum. |
2007-07-30 |
2023-08-12 |
rat |
| Hiroo Yamaguchi, Jie She. Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice. Molecular neurodegeneration. vol 2. 2007-07-30. PMID:17535435. |
we found that dj-1-/- mice at the age of 24-27 months have normal numbers of dopaminergic neurons in the substantia nigra and normal levels of dopamine and its major metabolites in the striatum. |
2007-07-30 |
2023-08-12 |
mouse |
| Deanna M Marchionini, Elin Lehrmann, Yaping Chu, Bin He, Caryl E Sortwell, Kevin G Becker, William J Freed, Jeffrey H Kordower, Timothy J Collie. Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease. Brain research. vol 1147. 2007-07-16. PMID:17368428. |
examination of gene expression in the developing striatum suggested an important role for the heparin binding growth factor family at time points relevant to establishment of dopaminergic innervation. |
2007-07-16 |
2023-08-12 |
Not clear |
| V Pedersen, W J Schmid. The neuroprotectant properties of glutamate antagonists and antiglutamatergic drugs. Neurotoxicity research. vol 2. issue 2-3. 2007-07-09. PMID:16787840. |
there are recent studies indicating that a transneuronal retrograde degeneration of the substantia nigra pars compacta neurons might be induced by a loss of function of dopaminergic synapses in the striatum. |
2007-07-09 |
2023-08-12 |
Not clear |
| Marine Hovakimyan, Stefan Jean-Pierre Haas, Oliver Schmitt, Bernd Gerber, Andreas Wree, Christian Andresse. Mesencephalic human neural progenitor cells transplanted into the neonatal hemiparkinsonian rat striatum differentiate into neurons and improve motor behaviour. Journal of anatomy. vol 209. issue 6. 2007-07-09. PMID:17118060. |
in the striatum, tyrosine hydroxylase-immunoreactive somata were also found, indicating a dopaminergic differentiation capacity of transplanted hnpcs in vivo. |
2007-07-09 |
2023-08-12 |
human |
| Vincenzo Di Matteo, Massimo Pierucci, Giuseppe Di Giovanni, Arcangelo Benigno, Ennio Esposit. The neurobiological bases for the pharmacotherapy of nicotine addiction. Current pharmaceutical design. vol 13. issue 12. 2007-07-09. PMID:17504235. |
the neurochemical data are consistent with neuroanatomical findings showing the presence of nicotinic acetylcholine receptors (nachrs) in the snc, the vta, and in projection areas of the central dopaminergic system such as the corpus striatum and the nucleus accumbens. |
2007-07-09 |
2023-08-12 |
Not clear |
| Jun Takahash. Stem cell therapy for Parkinson's disease. Expert review of neurotherapeutics. vol 7. issue 6. 2007-07-03. PMID:17563250. |
as an alternative, transplantation of stem cell-derived dopaminergic neurons into the striatum has been attempted, with the aim of stimulating local synapse formation and/or release of dopamine and cytokines from grafted cells. |
2007-07-03 |
2023-08-12 |
Not clear |
| Nathalie Breysse, Thomas Carlsson, Christian Winkler, Anders Björklund, Deniz Kiri. The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 22. 2007-06-13. PMID:17537955. |
here, we report that in animals subjected to an intrastriatal 6-hydroxydopamine lesion of the striatal dopaminergic afferent, the integrity of the host dopaminergic innervation outside the areas innervated by the graft is critical for optimal function of da neurons placed in the striatum. |
2007-06-13 |
2023-08-12 |
human |
| Jelena Mijatovic, Mikko Airavaara, Anu Planken, Petri Auvinen, Atso Raasmaja, T Petteri Piepponen, Frank Costantini, Liisa Ahtee, Mart Saarm. Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 18. 2007-06-06. PMID:17475787. |
we used knock-in men2b mice with the ret-men2b mutation to study the effects of constitutive ret activity on the brain dopaminergic system and found robustly increased concentrations of dopamine (da) and its metabolites in the striatum, cortex, and hypothalamus. |
2007-06-06 |
2023-08-12 |
mouse |
| David A Price, William A Owens, Georgianna G Gould, Alan Frazer, James L Roberts, Lynette C Daws, Andrea Giuffrid. CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatum. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17250681. |
in this study, we used in vitro and in vivo techniques to investigate whether cannabinoid agonists and antagonist could affect dopaminergic transmission in the striatum by acting at the dopamine transporter. |
2007-06-01 |
2023-08-12 |
mouse |
| Xavier Ligneau, Laurent Landais, David Perrin, Johanne Piriou, Marilyne Uguen, Emmanuel Denis, Philippe Robert, Régis Parmentier, Christelle Anaclet, Jian-Sheng Lin, Aude Burban, Jean-Michel Arrang, Jean-Charles Schwart. Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649. Biochemical pharmacology. vol 73. issue 8. 2007-05-31. PMID:17343831. |
dopac/dopamine ratios were enhanced in the prefrontal cortex but not in the striatum, indicating a selective activation of a sub-population of dopaminergic neurons. |
2007-05-31 |
2023-08-12 |
mouse |
| Walter Maetzler, Daniela Berg, Natalie Schalamberidze, Arthur Melms, Klaus Schott, Jakob C Mueller, Lucy Liaw, Thomas Gasser, Cordula Nitsc. Osteopontin is elevated in Parkinson's disease and its absence leads to reduced neurodegeneration in the MPTP model. Neurobiology of disease. vol 25. issue 3. 2007-05-17. PMID:17188882. |
loss of tyrosine-hydroxylase-positive cells in the sn and of dopaminergic fibers in the striatum was reduced 3 weeks after mptp intoxication in opn-null mice. |
2007-05-17 |
2023-08-12 |
mouse |
| E Ch Wolter. PD-related psychosis: pathophysiology with therapeutical strategies. Journal of neural transmission. Supplementum. issue 71. 2007-05-17. PMID:17447413. |
parkinson's disease (pd) is a chronic, neurodegenerative disease with degeneration of the central dopaminergic neurons in the substantia nigra, leading to a depletion of dopamine (da) in the striatum. |
2007-05-17 |
2023-08-12 |
Not clear |
| Li-Ping Liang, Jie Huang, Ruth Fulton, Brian J Day, Manisha Pate. An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 16. 2007-05-07. PMID:17442816. |
aeol11207 administered either by subcutaneous or oral routes protected against mptp-induced dopamine depletion in the striatum as well as dopaminergic neuronal loss, glutathione depletion, lipid peroxidation, and 3-nt formation in the ventral midbrain. |
2007-05-07 |
2023-08-12 |
mouse |
| T Obat. Nitric oxide and MPP+-induced hydroxyl radical generation. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 9. 2007-05-02. PMID:16463115. |
intraneuronal ca(2+) triggered by mpp(+) may be detrimental to the functioning of dopaminergic nerve terminals in the striatum. |
2007-05-02 |
2023-08-12 |
Not clear |
| Elin K I Andersson, Dwain K Irvin, Jessica Ahlsiö, Malin Parma. Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells. Experimental cell research. vol 313. issue 6. 2007-05-02. PMID:17291494. |
parkinson's disease (pd) is a debilitating motor function disorder due primarily to a loss of midbrain dopaminergic neurons and a subsequent reduction in dopaminergic innervation of the striatum. |
2007-05-02 |
2023-08-12 |
mouse |
| Andisheh Eslamboli, Marina Romero-Ramos, Corinna Burger, Tomas Bjorklund, Nicholas Muzyczka, Ronald J Mandel, Harry Baker, Rosalind M Ridley, Deniz Kiri. Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain. Brain : a journal of neurology. vol 130. issue Pt 3. 2007-04-16. PMID:17303591. |
histological analysis from animals overexpressing either the wt or a53t alpha -syn showed prominent degeneration of dopaminergic fibres in the striatum. |
2007-04-16 |
2023-08-12 |
human |
| Jeffrey N Joyce, Mark J Milla. Dopamine D3 receptor agonists for protection and repair in Parkinson's disease. Current opinion in pharmacology. vol 7. issue 1. 2007-04-12. PMID:17174156. |
parkinson's disease is a severe, age-related neurodegenerative disorder in which a loss of substantia nigra-derived dopaminergic pathways to the striatum triggers profound motor perturbation, as well as cognitive, sensory and mood deficits. |
2007-04-12 |
2023-08-12 |
Not clear |
| S Urakawa, H Hida, T Masuda, S Misumi, T-S Kim, H Nishin. Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats. Neuroscience. vol 144. issue 3. 2007-04-11. PMID:17161913. |
striatal damage was induced at an age of 8 weeks by injection of the neuro-toxins 6-hydroxydopamine (6-ohda) or quinolinic acid (qa) into the striatum, or by injection of 6-ohda into the substantia nigra (sn), which depleted nigrostriatal dopaminergic innervation. |
2007-04-11 |
2023-08-12 |
rat |