| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philippe Huot, André Paren. Dopaminergic neurons intrinsic to the striatum. Journal of neurochemistry. vol 101. issue 6. 2007-08-16. PMID:17286588. |
the striatum -- the largest integrative component of the basal ganglia -- harbors a population of neurons that express the enzyme tyrosine hydroxylase (th), a faithful marker of dopaminergic neurons. |
2007-08-16 |
2023-08-12 |
Not clear |
| Muzamil Ahmad, Seema Yousuf, M Badruzzaman Khan, Abdullah Shafique Ahmad, Sofiyan Saleem, Md Nasrul Hoda, Fakhrul Isla. Protective effects of ethanolic extract of Delphinium denudatum in a rat model of Parkinson's disease. Human & experimental toxicology. vol 25. issue 7. 2007-08-08. PMID:16898164. |
a significant decrease in the level of dopamine (da) and its metabolites and an increase in the number of dopaminergic d2 receptors in striatum were observed after 6-ohda injection, both parameters were significantly recovered with treatment of the extract. |
2007-08-08 |
2023-08-12 |
rat |
| Andreas Hald, Johan Van Beek, Julie Lothariu. Inflammation in Parkinson's disease: causative or epiphenomenal? Sub-cellular biochemistry. vol 42. 2007-08-06. PMID:17612055. |
not only have activated microglia and increased levels of inflammatory mediators been detected in the striatum of pd patients, but a large body of animal studies points to a contributory role of inflammation in dopaminergic cell loss. |
2007-08-06 |
2023-08-12 |
human |
| Pietro Mazzoni, Anna Hristova, John W Krakaue. Why don't we move faster? Parkinson's disease, movement vigor, and implicit motivation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 27. 2007-08-02. PMID:17611263. |
we propose that, analogous to the established role of dopamine in explicit reward-seeking behavior, the dopaminergic projection to the striatum provides a signal for implicit "motor motivation." |
2007-08-02 |
2023-08-12 |
human |
| X Y Chen, J Li, W Q Qi, S H She. Experimental change on dopaminergic neurons in striatum of Parkinson disease rats. Histology and histopathology. vol 22. issue 10. 2007-08-02. PMID:17616935. |
experimental change on dopaminergic neurons in striatum of parkinson disease rats. |
2007-08-02 |
2023-08-12 |
rat |
| Osamu Kitamura, Itsuo Tokunaga, Takako Gotohda, Shin-ichi Kub. Immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users. International journal of legal medicine. vol 121. issue 3. 2007-07-31. PMID:16622715. |
immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users. |
2007-07-31 |
2023-08-12 |
human |
| Osamu Kitamura, Itsuo Tokunaga, Takako Gotohda, Shin-ichi Kub. Immunohistochemical investigation of dopaminergic terminal markers and caspase-3 activation in the striatum of human methamphetamine users. International journal of legal medicine. vol 121. issue 3. 2007-07-31. PMID:16622715. |
these findings might indicate that dopaminergic terminal degeneration is induced in the striatum of some meth abusers. |
2007-07-31 |
2023-08-12 |
human |
| R E Nordquist, P Voorn, J G de Mooij-van Malsen, R N J M A Joosten, C M A Pennartz, L J M J Vanderschure. Augmented reinforcer value and accelerated habit formation after repeated amphetamine treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 8. 2007-07-30. PMID:17275266. |
augmented dopaminergic neurotransmission in the striatum. |
2007-07-30 |
2023-08-12 |
rat |
| Hiroo Yamaguchi, Jie She. Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice. Molecular neurodegeneration. vol 2. 2007-07-30. PMID:17535435. |
we found that dj-1-/- mice at the age of 24-27 months have normal numbers of dopaminergic neurons in the substantia nigra and normal levels of dopamine and its major metabolites in the striatum. |
2007-07-30 |
2023-08-12 |
mouse |
| Deanna M Marchionini, Elin Lehrmann, Yaping Chu, Bin He, Caryl E Sortwell, Kevin G Becker, William J Freed, Jeffrey H Kordower, Timothy J Collie. Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease. Brain research. vol 1147. 2007-07-16. PMID:17368428. |
examination of gene expression in the developing striatum suggested an important role for the heparin binding growth factor family at time points relevant to establishment of dopaminergic innervation. |
2007-07-16 |
2023-08-12 |
Not clear |
| V Pedersen, W J Schmid. The neuroprotectant properties of glutamate antagonists and antiglutamatergic drugs. Neurotoxicity research. vol 2. issue 2-3. 2007-07-09. PMID:16787840. |
there are recent studies indicating that a transneuronal retrograde degeneration of the substantia nigra pars compacta neurons might be induced by a loss of function of dopaminergic synapses in the striatum. |
2007-07-09 |
2023-08-12 |
Not clear |
| Marine Hovakimyan, Stefan Jean-Pierre Haas, Oliver Schmitt, Bernd Gerber, Andreas Wree, Christian Andresse. Mesencephalic human neural progenitor cells transplanted into the neonatal hemiparkinsonian rat striatum differentiate into neurons and improve motor behaviour. Journal of anatomy. vol 209. issue 6. 2007-07-09. PMID:17118060. |
in the striatum, tyrosine hydroxylase-immunoreactive somata were also found, indicating a dopaminergic differentiation capacity of transplanted hnpcs in vivo. |
2007-07-09 |
2023-08-12 |
human |
| Vincenzo Di Matteo, Massimo Pierucci, Giuseppe Di Giovanni, Arcangelo Benigno, Ennio Esposit. The neurobiological bases for the pharmacotherapy of nicotine addiction. Current pharmaceutical design. vol 13. issue 12. 2007-07-09. PMID:17504235. |
the neurochemical data are consistent with neuroanatomical findings showing the presence of nicotinic acetylcholine receptors (nachrs) in the snc, the vta, and in projection areas of the central dopaminergic system such as the corpus striatum and the nucleus accumbens. |
2007-07-09 |
2023-08-12 |
Not clear |
| Jun Takahash. Stem cell therapy for Parkinson's disease. Expert review of neurotherapeutics. vol 7. issue 6. 2007-07-03. PMID:17563250. |
as an alternative, transplantation of stem cell-derived dopaminergic neurons into the striatum has been attempted, with the aim of stimulating local synapse formation and/or release of dopamine and cytokines from grafted cells. |
2007-07-03 |
2023-08-12 |
Not clear |
| Nathalie Breysse, Thomas Carlsson, Christian Winkler, Anders Björklund, Deniz Kiri. The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 22. 2007-06-13. PMID:17537955. |
here, we report that in animals subjected to an intrastriatal 6-hydroxydopamine lesion of the striatal dopaminergic afferent, the integrity of the host dopaminergic innervation outside the areas innervated by the graft is critical for optimal function of da neurons placed in the striatum. |
2007-06-13 |
2023-08-12 |
human |
| Jelena Mijatovic, Mikko Airavaara, Anu Planken, Petri Auvinen, Atso Raasmaja, T Petteri Piepponen, Frank Costantini, Liisa Ahtee, Mart Saarm. Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 18. 2007-06-06. PMID:17475787. |
we used knock-in men2b mice with the ret-men2b mutation to study the effects of constitutive ret activity on the brain dopaminergic system and found robustly increased concentrations of dopamine (da) and its metabolites in the striatum, cortex, and hypothalamus. |
2007-06-06 |
2023-08-12 |
mouse |
| David A Price, William A Owens, Georgianna G Gould, Alan Frazer, James L Roberts, Lynette C Daws, Andrea Giuffrid. CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatum. Journal of neurochemistry. vol 101. issue 2. 2007-06-01. PMID:17250681. |
in this study, we used in vitro and in vivo techniques to investigate whether cannabinoid agonists and antagonist could affect dopaminergic transmission in the striatum by acting at the dopamine transporter. |
2007-06-01 |
2023-08-12 |
mouse |
| Xavier Ligneau, Laurent Landais, David Perrin, Johanne Piriou, Marilyne Uguen, Emmanuel Denis, Philippe Robert, Régis Parmentier, Christelle Anaclet, Jian-Sheng Lin, Aude Burban, Jean-Michel Arrang, Jean-Charles Schwart. Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649. Biochemical pharmacology. vol 73. issue 8. 2007-05-31. PMID:17343831. |
dopac/dopamine ratios were enhanced in the prefrontal cortex but not in the striatum, indicating a selective activation of a sub-population of dopaminergic neurons. |
2007-05-31 |
2023-08-12 |
mouse |
| Walter Maetzler, Daniela Berg, Natalie Schalamberidze, Arthur Melms, Klaus Schott, Jakob C Mueller, Lucy Liaw, Thomas Gasser, Cordula Nitsc. Osteopontin is elevated in Parkinson's disease and its absence leads to reduced neurodegeneration in the MPTP model. Neurobiology of disease. vol 25. issue 3. 2007-05-17. PMID:17188882. |
loss of tyrosine-hydroxylase-positive cells in the sn and of dopaminergic fibers in the striatum was reduced 3 weeks after mptp intoxication in opn-null mice. |
2007-05-17 |
2023-08-12 |
mouse |
| E Ch Wolter. PD-related psychosis: pathophysiology with therapeutical strategies. Journal of neural transmission. Supplementum. issue 71. 2007-05-17. PMID:17447413. |
parkinson's disease (pd) is a chronic, neurodegenerative disease with degeneration of the central dopaminergic neurons in the substantia nigra, leading to a depletion of dopamine (da) in the striatum. |
2007-05-17 |
2023-08-12 |
Not clear |