| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| André T R Goes, Cristiano R Jesse, Michelle S Antunes, Fernando V Lobo Ladd, Aliny A B Lobo Ladd, Cristiane Luchese, Natalia Paroul, Silvana P Boeir. Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins. Chemico-biological interactions. vol 279. 2018-01-03. PMID:29054324. |
these results corroborated with the neuroprotective effect of chrysin in the treatment of parkinson's disease and, indicated the mechanism involved throught the inflammatory cytokines, neurotrophic factors and recovery of dopaminergic neurons in striatum. |
2018-01-03 |
2023-08-13 |
mouse |
| Payam Piray, Hanneke E M den Ouden, Marieke E van der Schaaf, Ivan Toni, Roshan Cool. Dopaminergic Modulation of the Functional Ventrodorsal Architecture of the Human Striatum. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 1. 2018-01-02. PMID:26494799. |
dopaminergic modulation of the functional ventrodorsal architecture of the human striatum. |
2018-01-02 |
2023-08-13 |
human |
| Payam Piray, Hanneke E M den Ouden, Marieke E van der Schaaf, Ivan Toni, Roshan Cool. Dopaminergic Modulation of the Functional Ventrodorsal Architecture of the Human Striatum. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 1. 2018-01-02. PMID:26494799. |
using systematic pharmacological manipulation of dopamine d2-receptors and resting-state functional imaging, we defined the functional architecture of the human striatum and quantified the effects of dopaminergic drugs on intrinsic effective connectivity between striatal subregions. |
2018-01-02 |
2023-08-13 |
human |
| S Abad, J Camarasa, D Pubill, A Camins, E Escubed. Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits. Molecular neurobiology. vol 53. issue 10. 2017-12-25. PMID:26687233. |
in parallel, mdma produced a decrease in dopamine (da) levels in the striatum at 2w, which were restored 3 months later, suggesting dopaminergic terminal regeneration (sprouting phenomenon). |
2017-12-25 |
2023-08-13 |
mouse |
| Filipe C Matheus, Daniel Rial, Joana I Real, Cristina Lemos, Reinaldo N Takahashi, Leandro J Bertoglio, Rodrigo A Cunha, Rui D Predige. Temporal Dissociation of Striatum and Prefrontal Cortex Uncouples Anhedonia and Defense Behaviors Relevant to Depression in 6-OHDA-Lesioned Rats. Molecular neurobiology. vol 53. issue 6. 2017-12-22. PMID:26164273. |
the dorsolateral striatum (dls) processes motor and non-motor functions and undergoes extensive dopaminergic degeneration in parkinson's disease (pd). |
2017-12-22 |
2023-08-13 |
rat |
| Kamilla Blecharz-Klin, Agnieszka Piechal, Katarzyna Jawna-Zboińska, Justyna Pyrzanowska, Adriana Wawer, Ilona Joniec-Maciejak, Ewa Widy-Tyszkiewic. Paracetamol - Effect of early exposure on neurotransmission, spatial memory and motor performance in rats. Behavioural brain research. vol 323. 2017-12-13. PMID:28163096. |
these results indicate that early paracetamol exposure produces major changes in serotonergic and dopaminergic neurotransmission in the prefrontal cortex and striatum. |
2017-12-13 |
2023-08-13 |
rat |
| Caroline Calice da Silva, Bárbara Nunes Azevedo, Denise Cantarelli Machado, Eduardo R Zimmer, Leo Anderson Meira Martins, Jaderson Costa da Cost. Dissociation between dopaminergic response and motor behavior following intrastriatal, but not intravenous, transplant of bone marrow mononuclear stem cells in a mouse model of Parkinson's disease. Behavioural brain research. vol 324. 2017-12-13. PMID:28167338. |
parkinson's disease is characterized by the progressive loss of dopaminergic neurons from the substantia nigra, a process that leads to a dopamine deficiency in the striatum. |
2017-12-13 |
2023-08-13 |
mouse |
| David R Bonsall, Michelle Kokkinou, Mattia Veronese, Christopher Coello, Lisa A Wells, Oliver D Howe. Single cocaine exposure does not alter striatal pre-synaptic dopamine function in mice: an [ Journal of neurochemistry. vol 143. issue 5. 2017-12-07. PMID:28921596. |
our findings suggest that while the regulation of dopamine synthesis and release in the striatum have been shown to change with chronic cocaine use, leading to a reduced basal tone, these adaptations to pre-synaptic dopaminergic neurons are not initiated following a single exposure to the drug. |
2017-12-07 |
2023-08-13 |
mouse |
| Di Wen, Meiling An, Hongyan Gou, Xia Liu, Li Liu, Chunling Ma, Bin Con. Cholecystokinin-8 inhibits methamphetamine-induced neurotoxicity via an anti-oxidative stress pathway. Neurotoxicology. vol 57. 2017-11-21. PMID:27565679. |
we found that pretreatment of cholecystokinin-8 (cck-8) inhibited meth-induced brain cellular dopaminergic (da) damage in the striatum and substantia nigra, and related behavioural deficits and hyperthermia. |
2017-11-21 |
2023-08-13 |
Not clear |
| Neelam Shahani, Supriya Swarnkar, Vincenzo Giovinazzo, Jenny Morgenweck, Laura M Bohn, Catherina Scharager-Tapia, Bruce Pascal, Pablo Martinez-Acedo, Kshitij Khare, Srinivasa Subramania. RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Science signaling. vol 9. issue 454. 2017-11-20. PMID:27902448. |
the guanosine triphosphatase ras homolog enriched in the striatum (rhes) inhibits dopaminergic signaling in the striatum, is implicated in hd and l-dopa-induced dyskinesia, and has a role in striatal motor control. |
2017-11-20 |
2023-08-13 |
mouse |
| Tanara V Peres, Lin K Ong, Ana Paula Costa, Helena Eyng, Débora K R Venske, Dirleise Colle, Filipe M Gonçalves, Mark W Lopes, Marcelo Farina, Michael Aschner, Phillip W Dickson, Peter R Dunkley, Rodrigo B Lea. Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese. Metallomics : integrated biometal science. vol 8. issue 6. 2017-11-16. PMID:26790482. |
in the present study, we investigated the effects of mn exposure on the developing dopaminergic system, specifically tyrosine hydroxylase (th) protein and phosphorylation levels in the striatum of rats. |
2017-11-16 |
2023-08-13 |
rat |
| Inga B Fricke, Thomas Viel, Maik M Worlitzer, Franziska M Collmann, Alexis Vrachimis, Andreas Faust, Lydia Wachsmuth, Cornelius Faber, Frédéric Dollé, Michael T Kuhlmann, Klaus Schäfers, Sven Hermann, Jens C Schwamborn, Andreas H Jacob. 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis. The European journal of neuroscience. vol 43. issue 10. 2017-11-16. PMID:26950181. |
dopaminergic deafferentation of the striatum does not influence the generation of doublecortin-positive neuroblasts in the svz, but generates chronic astrogliosis in the nigrostriatal system. |
2017-11-16 |
2023-08-13 |
mouse |
| M Toritsuka, S Kimoto, K Muraki, M Kitagawa, T Kishimoto, A Sawa, K Tanigak. Regulation of striatal dopamine responsiveness by Notch/RBP-J signaling. Translational psychiatry. vol 7. issue 3. 2017-11-16. PMID:28267151. |
rbp-j deficiency drastically reduced dopamine release in the striatum and caused a subtle decrease in the number of dopaminergic neurons. |
2017-11-16 |
2023-08-13 |
Not clear |
| Jaron T Colas, Wolfgang M Pauli, Tobias Larsen, J Michael Tyszka, John P O'Dohert. Distinct prediction errors in mesostriatal circuits of the human brain mediate learning about the values of both states and actions: evidence from high-resolution fMRI. PLoS computational biology. vol 13. issue 10. 2017-11-13. PMID:29049406. |
prediction-error signals consistent with formal models of "reinforcement learning" (rl) have repeatedly been found within dopaminergic nuclei of the midbrain and dopaminoceptive areas of the striatum. |
2017-11-13 |
2023-08-13 |
human |
| Yeomoon Sim, Gunhyuk Park, Hyeyoon Eo, Eugene Huh, Pil Sung Gu, Seon-Pyo Hong, Youngmi Kim Pak, Myung Sook O. Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein. Neuroscience. vol 340. 2017-11-06. PMID:27771535. |
parkinson's disease (pd) is one of the progressive neurodegenerative diseases of whose condition is characterized by dopaminergic neuronal cell loss and dysfunction in the substantia nigra pars compacta (snpc) and the striatum. |
2017-11-06 |
2023-08-13 |
mouse |
| Thomas G McWilliams, Laura Howard, Sean Wyatt, Alun M Davie. TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Experimental neurology. vol 298. issue Pt A. 2017-11-06. PMID:28911883. |
in vivo, there was a significant reduction in the density of midbrain dopaminergic projections to the striatum in april-/- embryos compared with wild type littermates at e14. |
2017-11-06 |
2023-08-13 |
mouse |
| Kyung Moon Lee, Yujeong Lee, Hye Jeong Chun, Ah Hyun Kim, Ju Yeon Kim, Joo Yeon Lee, Akihito Ishigami, Jaewon Le. Neuroprotective and anti-inflammatory effects of morin in a murine model of Parkinson's disease. Journal of neuroscience research. vol 94. issue 10. 2017-11-03. PMID:27265894. |
in the mouse model, morin pretreatment ameliorated motor dysfunction, protected against dopaminergic neuronal losses in sn and striatum, and alleviated mptp-induced astrocyte activation. |
2017-11-03 |
2023-08-13 |
mouse |
| Ingrid Morales, Alberto Sanchez, Clara Rodriguez-Sabate, Manuel Rodrigue. Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model. PloS one. vol 12. issue 10. 2017-10-27. PMID:29028815. |
rats were injected in the lateral ventricles with 6-hydroxydopamine (25μg), inducing a dopaminergic denervation of the striatum not accompanied by non-selective tissue damage. |
2017-10-27 |
2023-08-13 |
rat |
| Anja Drinkut, Karsten Tillack, Durga P Meka, Jorg B Schulz, Sebastian Kügler, Edgar R Krame. Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model. Cell death & disease. vol 7. issue 9. 2017-10-25. PMID:27607574. |
to address this question we overexpressed gdnf in the striatum of mice deficient for ret in dopaminergic neurons and subsequently challenged these mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
2017-10-25 |
2023-08-13 |
mouse |
| Haisong Jiang, Sung-Ung Kang, Shuran Zhang, Senthilkumar Karuppagounder, Jinchong Xu, Yong-Kyu Lee, Bong-Gu Kang, Yunjong Lee, Jianmin Zhang, Olga Pletnikova, Juan C Troncoso, Shelia Pirooznia, Shaida A Andrabi, Valina L Dawson, Ted M Dawso. Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons. eNeuro. vol 3. issue 4. 2017-10-25. PMID:27622213. |
adult conditional pgc-1α knock-out mice show a significant loss of dopaminergic neurons that is accompanied by a reduction of dopamine in the striatum. |
2017-10-25 |
2023-08-13 |
mouse |