| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pil Sung Gu, Minho Moon, Jin Gyu Choi, Myung Sook O. Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing α-synuclein and ubiquitin levels in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model. The Journal of nutritional biochemistry. vol 39. 2018-01-17. PMID:27741433. |
in addition, immunohistochemical analysis indicated that me exhibits the protective effects against dopaminergic neuronal damage induced by mptp/p in the substantia nigra and striatum. |
2018-01-17 |
2023-08-13 |
mouse |
| Mei Liu, Adam D Bachstetter, Wayne A Cass, Jonathan Lifshitz, Guoying Bin. Pioglitazone Attenuates Neuroinflammation and Promotes Dopaminergic Neuronal Survival in the Nigrostriatal System of Rats after Diffuse Brain Injury. Journal of neurotrauma. vol 34. issue 2. 2018-01-12. PMID:27142118. |
loss of neurons was accompanied by increased extracellular dopamine (da) turnover in the striatum, indicating enhanced dopaminergic activity in functional compensation after nigrostriatal damage. |
2018-01-12 |
2023-08-13 |
rat |
| Tian Wang, Lijie Wang, Cuiting Li, Bing Han, Zhenhua Wang, Ji Li, Yan Lv, Shuyun Wang, Fenghua F. Hydroxysafflor Yellow A Improves Motor Dysfunction in the Rotenone-Induced Mice Model of Parkinson's Disease. Neurochemical research. vol 42. issue 5. 2018-01-09. PMID:28097465. |
hsya treatment increased not only the number of th-containing dopaminergic neurons in substantia nigra, but also the dopamine content in the striatum in pd mice. |
2018-01-09 |
2023-08-13 |
mouse |
| Kirsten E Schoonover, Lesley A McCollum, Rosalinda C Robert. Protein Markers of Neurotransmitter Synthesis and Release in Postmortem Schizophrenia Substantia Nigra. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 2. 2018-01-05. PMID:27550734. |
the substantia nigra (sn) provides the largest dopaminergic input to the brain, projects to the striatum (the primary locus of action for antipsychotic medication), and receives gabaergic and glutamatergic inputs. |
2018-01-05 |
2023-08-13 |
human |
| Aung Aung Kywe Moe, Gregory A Medely, Timothy Reeks, Thomas H J Burne, Darryl W Eyle. Short- and long-term effects of risperidone on catalepsy sensitisation and acquisition of conditioned avoidance response: Adolescent vs adult rats. Pharmacological research. vol 121. 2018-01-05. PMID:28414178. |
we examined short- and long-term changes in behaviour (catalepsy, locomotion and conditioned avoidance response (car)), and dopaminergic and serotonergic neurochemistry in the striatum and the nucleus accumbens. |
2018-01-05 |
2023-08-13 |
rat |
| André T R Goes, Cristiano R Jesse, Michelle S Antunes, Fernando V Lobo Ladd, Aliny A B Lobo Ladd, Cristiane Luchese, Natalia Paroul, Silvana P Boeir. Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins. Chemico-biological interactions. vol 279. 2018-01-03. PMID:29054324. |
these results corroborated with the neuroprotective effect of chrysin in the treatment of parkinson's disease and, indicated the mechanism involved throught the inflammatory cytokines, neurotrophic factors and recovery of dopaminergic neurons in striatum. |
2018-01-03 |
2023-08-13 |
mouse |
| Payam Piray, Hanneke E M den Ouden, Marieke E van der Schaaf, Ivan Toni, Roshan Cool. Dopaminergic Modulation of the Functional Ventrodorsal Architecture of the Human Striatum. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 1. 2018-01-02. PMID:26494799. |
dopaminergic modulation of the functional ventrodorsal architecture of the human striatum. |
2018-01-02 |
2023-08-13 |
human |
| Payam Piray, Hanneke E M den Ouden, Marieke E van der Schaaf, Ivan Toni, Roshan Cool. Dopaminergic Modulation of the Functional Ventrodorsal Architecture of the Human Striatum. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 1. 2018-01-02. PMID:26494799. |
using systematic pharmacological manipulation of dopamine d2-receptors and resting-state functional imaging, we defined the functional architecture of the human striatum and quantified the effects of dopaminergic drugs on intrinsic effective connectivity between striatal subregions. |
2018-01-02 |
2023-08-13 |
human |
| S Abad, J Camarasa, D Pubill, A Camins, E Escubed. Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits. Molecular neurobiology. vol 53. issue 10. 2017-12-25. PMID:26687233. |
in parallel, mdma produced a decrease in dopamine (da) levels in the striatum at 2w, which were restored 3 months later, suggesting dopaminergic terminal regeneration (sprouting phenomenon). |
2017-12-25 |
2023-08-13 |
mouse |
| Filipe C Matheus, Daniel Rial, Joana I Real, Cristina Lemos, Reinaldo N Takahashi, Leandro J Bertoglio, Rodrigo A Cunha, Rui D Predige. Temporal Dissociation of Striatum and Prefrontal Cortex Uncouples Anhedonia and Defense Behaviors Relevant to Depression in 6-OHDA-Lesioned Rats. Molecular neurobiology. vol 53. issue 6. 2017-12-22. PMID:26164273. |
the dorsolateral striatum (dls) processes motor and non-motor functions and undergoes extensive dopaminergic degeneration in parkinson's disease (pd). |
2017-12-22 |
2023-08-13 |
rat |
| Kamilla Blecharz-Klin, Agnieszka Piechal, Katarzyna Jawna-Zboińska, Justyna Pyrzanowska, Adriana Wawer, Ilona Joniec-Maciejak, Ewa Widy-Tyszkiewic. Paracetamol - Effect of early exposure on neurotransmission, spatial memory and motor performance in rats. Behavioural brain research. vol 323. 2017-12-13. PMID:28163096. |
these results indicate that early paracetamol exposure produces major changes in serotonergic and dopaminergic neurotransmission in the prefrontal cortex and striatum. |
2017-12-13 |
2023-08-13 |
rat |
| Caroline Calice da Silva, Bárbara Nunes Azevedo, Denise Cantarelli Machado, Eduardo R Zimmer, Leo Anderson Meira Martins, Jaderson Costa da Cost. Dissociation between dopaminergic response and motor behavior following intrastriatal, but not intravenous, transplant of bone marrow mononuclear stem cells in a mouse model of Parkinson's disease. Behavioural brain research. vol 324. 2017-12-13. PMID:28167338. |
parkinson's disease is characterized by the progressive loss of dopaminergic neurons from the substantia nigra, a process that leads to a dopamine deficiency in the striatum. |
2017-12-13 |
2023-08-13 |
mouse |
| David R Bonsall, Michelle Kokkinou, Mattia Veronese, Christopher Coello, Lisa A Wells, Oliver D Howe. Single cocaine exposure does not alter striatal pre-synaptic dopamine function in mice: an [ Journal of neurochemistry. vol 143. issue 5. 2017-12-07. PMID:28921596. |
our findings suggest that while the regulation of dopamine synthesis and release in the striatum have been shown to change with chronic cocaine use, leading to a reduced basal tone, these adaptations to pre-synaptic dopaminergic neurons are not initiated following a single exposure to the drug. |
2017-12-07 |
2023-08-13 |
mouse |
| Di Wen, Meiling An, Hongyan Gou, Xia Liu, Li Liu, Chunling Ma, Bin Con. Cholecystokinin-8 inhibits methamphetamine-induced neurotoxicity via an anti-oxidative stress pathway. Neurotoxicology. vol 57. 2017-11-21. PMID:27565679. |
we found that pretreatment of cholecystokinin-8 (cck-8) inhibited meth-induced brain cellular dopaminergic (da) damage in the striatum and substantia nigra, and related behavioural deficits and hyperthermia. |
2017-11-21 |
2023-08-13 |
Not clear |
| Neelam Shahani, Supriya Swarnkar, Vincenzo Giovinazzo, Jenny Morgenweck, Laura M Bohn, Catherina Scharager-Tapia, Bruce Pascal, Pablo Martinez-Acedo, Kshitij Khare, Srinivasa Subramania. RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Science signaling. vol 9. issue 454. 2017-11-20. PMID:27902448. |
the guanosine triphosphatase ras homolog enriched in the striatum (rhes) inhibits dopaminergic signaling in the striatum, is implicated in hd and l-dopa-induced dyskinesia, and has a role in striatal motor control. |
2017-11-20 |
2023-08-13 |
mouse |
| Tanara V Peres, Lin K Ong, Ana Paula Costa, Helena Eyng, Débora K R Venske, Dirleise Colle, Filipe M Gonçalves, Mark W Lopes, Marcelo Farina, Michael Aschner, Phillip W Dickson, Peter R Dunkley, Rodrigo B Lea. Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese. Metallomics : integrated biometal science. vol 8. issue 6. 2017-11-16. PMID:26790482. |
in the present study, we investigated the effects of mn exposure on the developing dopaminergic system, specifically tyrosine hydroxylase (th) protein and phosphorylation levels in the striatum of rats. |
2017-11-16 |
2023-08-13 |
rat |
| Inga B Fricke, Thomas Viel, Maik M Worlitzer, Franziska M Collmann, Alexis Vrachimis, Andreas Faust, Lydia Wachsmuth, Cornelius Faber, Frédéric Dollé, Michael T Kuhlmann, Klaus Schäfers, Sven Hermann, Jens C Schwamborn, Andreas H Jacob. 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis. The European journal of neuroscience. vol 43. issue 10. 2017-11-16. PMID:26950181. |
dopaminergic deafferentation of the striatum does not influence the generation of doublecortin-positive neuroblasts in the svz, but generates chronic astrogliosis in the nigrostriatal system. |
2017-11-16 |
2023-08-13 |
mouse |
| M Toritsuka, S Kimoto, K Muraki, M Kitagawa, T Kishimoto, A Sawa, K Tanigak. Regulation of striatal dopamine responsiveness by Notch/RBP-J signaling. Translational psychiatry. vol 7. issue 3. 2017-11-16. PMID:28267151. |
rbp-j deficiency drastically reduced dopamine release in the striatum and caused a subtle decrease in the number of dopaminergic neurons. |
2017-11-16 |
2023-08-13 |
Not clear |
| Jaron T Colas, Wolfgang M Pauli, Tobias Larsen, J Michael Tyszka, John P O'Dohert. Distinct prediction errors in mesostriatal circuits of the human brain mediate learning about the values of both states and actions: evidence from high-resolution fMRI. PLoS computational biology. vol 13. issue 10. 2017-11-13. PMID:29049406. |
prediction-error signals consistent with formal models of "reinforcement learning" (rl) have repeatedly been found within dopaminergic nuclei of the midbrain and dopaminoceptive areas of the striatum. |
2017-11-13 |
2023-08-13 |
human |
| Yeomoon Sim, Gunhyuk Park, Hyeyoon Eo, Eugene Huh, Pil Sung Gu, Seon-Pyo Hong, Youngmi Kim Pak, Myung Sook O. Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein. Neuroscience. vol 340. 2017-11-06. PMID:27771535. |
parkinson's disease (pd) is one of the progressive neurodegenerative diseases of whose condition is characterized by dopaminergic neuronal cell loss and dysfunction in the substantia nigra pars compacta (snpc) and the striatum. |
2017-11-06 |
2023-08-13 |
mouse |