| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A S Undie, E Friedma. Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain. The Journal of pharmacology and experimental therapeutics. vol 253. issue 3. 1990-07-31. PMID:1972756. |
on examining the effect of skf38393 in several brain regions, the highest dopaminergic stimulation of inositol phosphates formation was obtained in the amygdala, followed by the hippocampus and then the striatum and frontal cortex. |
1990-07-31 |
2023-08-11 |
rat |
| E C Hirsch, C Duyckaerts, F Javoy-Agid, J J Hauw, Y Agi. Does adrenal graft enhance recovery of dopaminergic neurons in Parkinson's disease? Annals of neurology. vol 27. issue 6. 1990-07-31. PMID:2360804. |
it suggests, however, that adrenal medulla grafts may stimulate the sprouting of striatal dopaminergic fibers in a limited zone of the grafted striatum. |
1990-07-31 |
2023-08-11 |
human |
| M Valchár, J J Bonnet, J Costenti. Chronic modification of dopaminergic transmission and its effects on binding characteristics of dopamine transporter ligand 3H-GBR 12783 in the striatum. Activitas nervosa superior. vol 31. issue 4. 1990-07-24. PMID:2561622. |
chronic modification of dopaminergic transmission and its effects on binding characteristics of dopamine transporter ligand 3h-gbr 12783 in the striatum. |
1990-07-24 |
2023-08-11 |
Not clear |
| J F Marshall, A J Rosenstei. Age-related decline in rat striatal dopamine metabolism is regionally homogeneous. Neurobiology of aging. vol 11. issue 2. 1990-07-11. PMID:2348901. |
however, for none of these measures was the age x region interaction significant, suggesting that the decline in these markers of presynaptic dopaminergic function occurs uniformly throughout the striatum. |
1990-07-11 |
2023-08-11 |
rat |
| S E Lindley, K J Lookingland, K E Moor. Activation of tuberoinfundibular but not tuberohypophysial dopaminergic neurons following intracerebroventricular administration of alpha-melanocyte-stimulating hormone. Neuroendocrinology. vol 51. issue 4. 1990-07-05. PMID:2161087. |
the effect of alpha-melanocyte-stimulating hormone (alpha msh) on the activity of different central dopaminergic neurons in the male rat was determined by measuring the concentration of 3,4-dihydroxyphenylacetic acid (dopac) and the accumulation of 3,4-dihydroxyphenylalanine (dopa) following the administration of a decarboxylase inhibitor in brain regions that contain terminals of nigrostriatal (striatum), mesolimbic (nucleus accumbens), tuberoinfundibular (median eminence) and tuberohypophysial (neural and intermediate lobe of the pituitary) dopaminergic neurons. |
1990-07-05 |
2023-08-11 |
rat |
| Y G Gao, R J Baldessarini, N S Kula, J L Neumeye. Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues. Journal of medicinal chemistry. vol 33. issue 6. 1990-06-28. PMID:1971309. |
the dopaminergic receptor affinities of these compounds and their 2-unsubstituted counterparts (r)-(-)-apomorphine (r(-)-apo, r-1), (s)-(+)-apomorphine (s(+)-apo, s-1), and (r)-(-)-n-n-propylnorapomorphine (r(-)-npa, r-2), as well as those of (r)-(-)-2-chloroapomorphine (r(-)-2-cl-apo, r-6), (r)-(-)-2-bromoapomorphine (r(-)-2-br-apo, r-6), were determined with tissue membrane preparations of corpus striatum from rat brain. |
1990-06-28 |
2023-08-11 |
rat |
| F C Liu, A M Graybiel, S B Dunnett, R W Baughma. Intrastriatal grafts derived from fetal striatal primordia: II. Reconstitution of cholinergic and dopaminergic systems. The Journal of comparative neurology. vol 295. issue 1. 1990-06-27. PMID:1971286. |
reconstitution of striatal cholinergic and dopaminergic systems was studied in intrastriatal grafts derived from embryonic day 15 rat striatal primordia and implanted into adult host rats in which unilateral ibotenic acid lesions had previously been made in the striatum. |
1990-06-27 |
2023-08-11 |
rat |
| K Mizukawa, Y H Sora, N Ogaw. Ultrastructural changes of the substantia nigra, ventral tegmental area and striatum in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. Research communications in chemical pathology and pharmacology. vol 67. issue 3. 1990-06-26. PMID:2343182. |
thus, the effect of mptp treatment is inhomogenous within the mouse striatum, as would be expected from the appearance of ultrastructural changes in only some of the dopaminergic neurons in the snc. |
1990-06-26 |
2023-08-11 |
mouse |
| P J Fletcher, M Davie. The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone. British journal of pharmacology. vol 99. issue 3. 1990-06-06. PMID:2139586. |
increased dopaminergic neurotransmission in the striatum induces a general behavioural activation, which under certain conditions facilitates feeding. |
1990-06-06 |
2023-08-11 |
rat |
| Y Masuo, D Pélaprat, M N Montagne, D Scherman, W Rostèn. Regulation of neurotensin-containing neurons in the rat striatum and substantia nigra. Effects of unilateral nigral lesion with 6-hydroxydopamine on neurotensin content and its binding site density. Brain research. vol 510. issue 2. 1990-06-04. PMID:1970504. |
on the other hand, nt binding sites decreased in the ipsilateral striatum and substantia nigra, which reflected the destruction of dopaminergic elements in these regions. |
1990-06-04 |
2023-08-11 |
rat |
| T Zetterström, M Fillen. Local administration of flurazepam has different effects on dopamine release in striatum and nucleus accumbens: a microdialysis study. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:2109839. |
these results suggest that the dopaminergic projection to the nucleus accumbens is more sensitive to benzodiazepine-induced inhibition than the projection to the striatum. |
1990-05-30 |
2023-08-11 |
Not clear |
| J Peris, S J Boyson, W A Cass, P Curella, L P Dwoskin, G Larson, L H Lin, R P Yasuda, N R Zahnise. Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. The Journal of pharmacology and experimental therapeutics. vol 253. issue 1. 1990-05-30. PMID:2329520. |
our neurochemical experiments focused primarily on the striatum; however, quantitative autoradiography was used to measure d-1 and d-2 da receptors in both cell body and terminal regions of the nigrostriatal and mesolimbic dopaminergic pathways. |
1990-05-30 |
2023-08-11 |
rat |
| I Kanazawa, M Kimura, M Murata, Y Tanaka, F Ch. Choreic movements in the macaque monkey induced by kainic acid lesions of the striatum combined with L-dopa. Pharmacological, biochemical and physiological studies on neural mechanisms. Brain : a journal of neurology. vol 113 ( Pt 2). 1990-05-25. PMID:1970271. |
it is, therefore, assumed that certain populations of 'activated' nigrostriatal dopaminergic neurons which innervate the unlesioned area of the striatum may be more likely to attain a level of activity, induced by l-dopa, sufficient to produce choreic movements in the contralateral limbs. |
1990-05-25 |
2023-08-11 |
monkey |
| J A Swart, J F van der Werf, T Wiegman, A M Paans, W Vaalburg, J Kor. In vivo binding of spiperone and N-methylspiperone to dopaminergic and serotonergic sites in the rat brain: multiple modeling and implications for PET scanning. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 3. 1990-05-25. PMID:1970341. |
nonlinear regression analysis shows that the in vivo specific binding of 3h-labeled spiperone in the frontal cortex (mainly serotonergic) can be described by a noninteracting sites model, whereas the specific binding in the striatum (mainly dopaminergic) can best be described by models that lead to sigmoid saturation curves. |
1990-05-25 |
2023-08-11 |
rat |
| E Salmon, D J Brooks, K L Leenders, D R Turton, S P Hume, J E Cremer, T Jones, R S Frackowia. A two-compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 3. 1990-05-25. PMID:2329119. |
s-[11c]nomifensine (s-[11c]nmf) is a positron-emitting tracer suitable for positron emission tomography, which binds to both dopaminergic and noradrenergic reuptake sites in the striatum and the thalamus. |
1990-05-25 |
2023-08-11 |
human |
| E Salmon, D J Brooks, K L Leenders, D R Turton, S P Hume, J E Cremer, T Jones, R S Frackowia. A two-compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 3. 1990-05-25. PMID:2329119. |
assuming that the cerebellar volume of distribution of [11c]nmf represents the nonspecific volume of distribution of the tracer in striatum and thalamus, we have calculated an equilibrium partition coefficient for [11c]nmf between freely exchanging specific and nonspecific compartments in these regions, representing its "binding potential" to dopaminergic or noradrenergic uptake sites (or complexes). |
1990-05-25 |
2023-08-11 |
human |
| M C Bohn, M Kanuick. Bilateral recovery of striatal dopamine after unilateral adrenal grafting into the striatum of the 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-treated mouse. Journal of neuroscience research. vol 25. issue 3. 1990-05-24. PMID:1969970. |
these observations suggest that adrenal tissue grafted into the striatum, whether it remains viable or not, has more widespread biochemical effects on the host dopaminergic system than previously recognized. |
1990-05-24 |
2023-08-11 |
mouse |
| K W Lang. Behavioural effects and supersensitivity in the rat following intranigral MPTP and MPP+ administration. European journal of pharmacology. vol 175. issue 1. 1990-05-24. PMID:2323346. |
these results suggest that the neurotoxicity of mptp is age-dependent in the rat, and that mptp has neurotoxic effects on the nigrostriatal dopaminergic system in old rats and induces dopamine receptor supersensitivity in the denervated striatum. |
1990-05-24 |
2023-08-11 |
rat |
| P R Lowenstein, J N Joyce, J T Coyle, J F Marshal. Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322836. |
striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic m1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. |
1990-05-21 |
2023-08-11 |
human |
| P R Lowenstein, J N Joyce, J T Coyle, J F Marshal. Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322836. |
the distribution of cholinergic pre- and postsynaptic markers and dopaminergic presynaptic markers was analyzed in the adult human striatum, using quantitative receptor autoradiography. |
1990-05-21 |
2023-08-11 |
human |