| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Salmon, D J Brooks, K L Leenders, D R Turton, S P Hume, J E Cremer, T Jones, R S Frackowia. A two-compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 3. 1990-05-25. PMID:2329119. |
assuming that the cerebellar volume of distribution of [11c]nmf represents the nonspecific volume of distribution of the tracer in striatum and thalamus, we have calculated an equilibrium partition coefficient for [11c]nmf between freely exchanging specific and nonspecific compartments in these regions, representing its "binding potential" to dopaminergic or noradrenergic uptake sites (or complexes). |
1990-05-25 |
2023-08-11 |
human |
| M C Bohn, M Kanuick. Bilateral recovery of striatal dopamine after unilateral adrenal grafting into the striatum of the 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-treated mouse. Journal of neuroscience research. vol 25. issue 3. 1990-05-24. PMID:1969970. |
these observations suggest that adrenal tissue grafted into the striatum, whether it remains viable or not, has more widespread biochemical effects on the host dopaminergic system than previously recognized. |
1990-05-24 |
2023-08-11 |
mouse |
| K W Lang. Behavioural effects and supersensitivity in the rat following intranigral MPTP and MPP+ administration. European journal of pharmacology. vol 175. issue 1. 1990-05-24. PMID:2323346. |
these results suggest that the neurotoxicity of mptp is age-dependent in the rat, and that mptp has neurotoxic effects on the nigrostriatal dopaminergic system in old rats and induces dopamine receptor supersensitivity in the denervated striatum. |
1990-05-24 |
2023-08-11 |
rat |
| P R Lowenstein, J N Joyce, J T Coyle, J F Marshal. Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322836. |
striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic m1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. |
1990-05-21 |
2023-08-11 |
human |
| P R Lowenstein, J N Joyce, J T Coyle, J F Marshal. Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322836. |
the distribution of cholinergic pre- and postsynaptic markers and dopaminergic presynaptic markers was analyzed in the adult human striatum, using quantitative receptor autoradiography. |
1990-05-21 |
2023-08-11 |
human |
| P R Lowenstein, J N Joyce, J T Coyle, J F Marshal. Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322836. |
our data show that cholinergic and dopaminergic terminals, and m1 receptors are enriched in the matrix of the adult human striatum. |
1990-05-21 |
2023-08-11 |
human |
| J J Robert, M Orosco, C Rouch, Y Cohen, C Jacquo. Opposite dopaminergic activity in lateral and median hypothalamic nuclei in relation to the feeding effect of D-Ser2-Leu-Enk-Thr6 (DSLET). Brain research. vol 510. issue 1. 1990-05-21. PMID:2322848. |
the leu-enkephalin analogue d-ser2-leu-enk-thr6 (dslet) had been shown to enhance feeding in rats, increase dopaminergic activity in the striatum like other opiate agonists, and particularly to decrease dopaminergic activity in the hypothalamus. |
1990-05-21 |
2023-08-11 |
rat |
| I Kanazaw. [Choreic movements and dopamine--implications to the underlying neural mechanisms involved]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2517049. |
1) a massive loss of gabaergic inhibitory neurones in the striatum induces disinhibitory effects on nigral dopaminergic neurones, which causes activation of dopaminergic neurones and choreic movements. |
1990-05-04 |
2023-08-11 |
monkey |
| I Kanazaw. [Choreic movements and dopamine--implications to the underlying neural mechanisms involved]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2517049. |
3) a massive loss of neurones in the striatum causes a loss of post-synaptic components of dopaminergic terminals. |
1990-05-04 |
2023-08-11 |
monkey |
| I Kanazaw. [Choreic movements and dopamine--implications to the underlying neural mechanisms involved]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2517049. |
this may further cause rearrangements and compensatory changes in dopaminergic terminals in the spared striatum. |
1990-05-04 |
2023-08-11 |
monkey |
| T Itoh, S Murai, H Nagahama, H Miyate, E Abe, H Fujiwara, Y Sait. Effects of 24-hr fasting on methamphetamine- and apomorphine-induced locomotor activities, and on monoamine metabolism in mouse corpus striatum and nucleus accumbens. Pharmacology, biochemistry, and behavior. vol 35. issue 2. 1990-05-03. PMID:2320647. |
these results suggest that the locomotor activity in fasting mice may be increased by a change in the sensitivity of dopaminergic neurons in the corpus striatum. |
1990-05-03 |
2023-08-11 |
mouse |
| J O Rinne, P Lönnberg, P Marjamäk. Age-dependent decline in human brain dopamine D1 and D2 receptors. Brain research. vol 508. issue 2. 1990-04-09. PMID:2407314. |
the results show that the dopaminergic system degenerates in the aging striatum and may contribute to the frequent occurrence of extrapyramidal symptoms in the elderly. |
1990-04-09 |
2023-08-11 |
human |
| A Imperato, L Angelucc. The effects of clozapine and fluperlapine on the in vivo release and metabolism of dopamine in the striatum and in the prefrontal cortex of freely moving rats. Psychopharmacology bulletin. vol 25. issue 3. 1990-04-04. PMID:2576318. |
the effects of the two atypical neuroleptics clozapine and fluperlapine on the dopaminergic function in the striatum and in the prefrontal cortex were studied using the transversal microdialysis technique in awake, freely moving rats. |
1990-04-04 |
2023-08-11 |
rat |
| R Raisman-Vozari, J A Girault, S Moussaoui, C Feuerstein, P Jenner, C D Marsden, Y Agi. Lack of change in striatal DARPP-32 levels following nigrostriatal dopaminergic lesions in animals and in parkinsonian syndromes in man. Brain research. vol 507. issue 1. 1990-03-19. PMID:2105823. |
the present study was performed to determine the effect of a nearly complete nigrostriatal dopaminergic denervation on darpp-32 levels in the striatum from animals and parkinsonian patients. |
1990-03-19 |
2023-08-11 |
rat |
| R Raisman-Vozari, J A Girault, S Moussaoui, C Feuerstein, P Jenner, C D Marsden, Y Agi. Lack of change in striatal DARPP-32 levels following nigrostriatal dopaminergic lesions in animals and in parkinsonian syndromes in man. Brain research. vol 507. issue 1. 1990-03-19. PMID:2105823. |
these results indicate that dopaminergic striatal denervation did not modify the amount of darpp-32 in the striatum, suggesting that the expression of darpp-32, a protein which mediates some of the effects of dopamine in striatal neurons, is independent from the dopaminergic innervation. |
1990-03-19 |
2023-08-11 |
rat |
| R Decombe, J P Rivot, D Aunis, N Abrous, M Peschanski, J P Herma. Importance of catecholamine release for the functional action of intrastriatal implants of adrenal medullary cells: pharmacological analysis and in vivo electrochemistry. Experimental neurology. vol 107. issue 2. 1990-03-16. PMID:2105897. |
the striatal dopaminergic input was extensively destroyed beforehand to preclude the possibility of reinnervation of the striatum by endogenous dopaminergic neurons. |
1990-03-16 |
2023-08-11 |
rat |
| N N Oleshk. [Effect of damage of the nigro-neostriatal dopaminergic system by MPTP on the transmission of corticofugal impulses to the neurons of the caudate nucleus]. Fiziologicheskii zhurnal. vol 35. issue 6. 1990-03-15. PMID:2558913. |
a conclusion is made that dopaminergic nigro-striatum system exerts a protective action on the impulse transfer on monosynaptic connections from the cortex to striatum. |
1990-03-15 |
2023-08-11 |
Not clear |
| M P Caligiuri, H S Bracha, J B Loh. Asymmetry of neuroleptic-induced rigidity: development of quantitative methods and clinical correlates. Psychiatry research. vol 30. issue 3. 1990-03-08. PMID:2575771. |
since parkinsonism reflects dopamine receptor blockade by neuroleptic medication, probably in the striatum, we suggest that the lowered susceptibility of the right striatum to drug-induced parkinsonism supports the hypothesis that striatal dopaminergic activity may be asymmetric and more marked in the right striatum among recently treated patients. |
1990-03-08 |
2023-08-11 |
Not clear |
| R L Dorri. Interactions of nicotinamide with dopamine receptors in vivo. Pharmacology, biochemistry, and behavior. vol 33. issue 4. 1990-03-06. PMID:2533358. |
relative decreases in the 2-hr ratio of accumulation of this dopamine receptor radioligand in the dopaminergic corpus striatum ("specific" plus "nonspecific binding") and the nondopaminergic cerebellum ("nonspecific binding" only) were used to evaluate nicotinamide for possible effects on the dopamine receptor. |
1990-03-06 |
2023-08-11 |
mouse |
| Y K Fung, J A Reed, Y S La. Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats. General pharmacology. vol 20. issue 5. 1990-02-21. PMID:2606336. |
no change in the characteristics of dopaminergic receptors and the rate of dopamine turnover was detected in the striatum. |
1990-02-21 |
2023-08-11 |
rat |