| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R F Seegal, B Bush, K O Brosc. Sub-chronic exposure of the adult rat to Aroclor 1254 yields regionally-specific changes in central dopaminergic function. Neurotoxicology. vol 12. issue 1. 1991-05-10. PMID:2014069. |
the susceptibility of the striatum and lateral olfactory tract to insult by pcbs may be due to their innervation by midbrain dopaminergic neurons which have been shown to be particularly sensitive to insult from environmental, infectious and pharmacologic agents. |
1991-05-10 |
2023-08-11 |
rat |
| I Date, S Asari, A Nishimoto, D L Felte. [Adrenal medullary graft induces recovery of the host nigrostriatal dopaminergic system in MPTP-induced mouse model of Parkinson's disease]. No to shinkei = Brain and nerve. vol 42. issue 12. 1991-05-10. PMID:2083133. |
c57bl/6 mice show decreased dopaminergic fibers and dopamine concentration in the striatum following systemic injection of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (mptp). |
1991-05-10 |
2023-08-11 |
mouse |
| C R Gerfen, J F McGinty, W S Youn. Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 4. 1991-05-09. PMID:1707092. |
relative levels of peptide mrna expression in the patch and matrix compartments of the dorsolateral striatum were compared among control rats, rats treated for 10 d with apomorphine, rats with unilateral 6-hydroxydopamine (6-ohda) lesions of the nigrostriatal dopaminergic system, and rats with nigrostriatal dopaminergic lesions followed 2 weeks later by 10 d of apomorphine treatment. |
1991-05-09 |
2023-08-11 |
rat |
| N F Suvorov, N L Voĭlokova, A I Gorbachevskaia, Iu M Driagin, O G Chivilev. [The participation of the glutaminergic and dopaminergic systems of the neostriatum in the organization of conditioned food reflexes]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 76. issue 11. 1991-05-08. PMID:1964420. |
exclusion of nigral, dopaminergic input into the striatum led to impairment of conditioning. |
1991-05-08 |
2023-08-11 |
Not clear |
| A Gonzalez, W J Smeet. Comparative analysis of dopamine and tyrosine hydroxylase immunoreactivities in the brain of two amphibians, the anuran Rana ridibunda and the urodele Pleurodeles waltlii. The Journal of comparative neurology. vol 303. issue 3. 1991-05-01. PMID:1672535. |
whereas the nucleus accumbens in rana contains the densest dai plexus, in pleurodeles the dopaminergic innervation of the striatum prevails. |
1991-05-01 |
2023-08-11 |
Not clear |
| M Watanabe, M Kinuya, G Mamiya, T Tatsunuma, M Nagayoshi, T Matsutani, Y Tsukad. Increased uptake sites for serotonin and dopamine with decreased S2 serotonin receptors in microencephalic rat brain. Neurochemical research. vol 15. issue 10. 1991-04-25. PMID:2077427. |
methylazoxymethanol (mam)-induced cerebral hypoplasia resulted in a significant increase in densities of both serotonin uptake sites in frontal cortex and dopamine uptake sites in striatum, suggesting serotonergic and dopaminergic axons terminals were compressed in the smaller brain volumes. |
1991-04-25 |
2023-08-11 |
rat |
| C Hyman, M Hofer, Y A Barde, M Juhasz, G D Yancopoulos, S P Squinto, R M Lindsa. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature. vol 350. issue 6315. 1991-04-19. PMID:2005978. |
a protein partially purified from bovine striatum, a target of nigral dopaminergic neurons, with characteristics apparently similar to those of bdnf, can enhance the survival of dopaminergic neurons in mesencephalic cultures. |
1991-04-19 |
2023-08-11 |
cattle |
| N Natsukari, H Hanai, T Matsunaga, M Fujit. Synergistic activation of brain adenylate cyclase by calmodulin, and either GTP or catecholamines including dopamine. Brain research. vol 534. issue 1-2. 1991-04-18. PMID:1963559. |
the effects of calmodulin (cam), guanosine triphosphate (gtp) and dopaminergic or beta-adrenergic agonists on the activities of adenylate cyclase were studied in egta-washed lysed synaptosomal membranes from rat striatum and cerebral cortex. |
1991-04-18 |
2023-08-11 |
rat |
| C Yoshihara, N Saito, K Taniyama, C Tanak. Differential localization of four subspecies of protein kinase C in the rat striatum and substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 3. 1991-04-17. PMID:1672152. |
the double-staining and lesion studies revealed that the alpha-pkc-immunopositive neurons in the striatum were intrinsic cholinergic neurons, and that most of the alpha-pkc-immunoreactive neurons in the sn were dopaminergic neurons. |
1991-04-17 |
2023-08-11 |
rat |
| L J Fisher, H A Jinnah, L C Kale, G A Higgins, F H Gag. Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-dopa. Neuron. vol 6. issue 3. 1991-04-16. PMID:1672072. |
these results suggest that primary fibroblasts genetically altered to express th have the capacity to deliver l-dopa locally to the striatum in quantities sufficient to compensate partially for the loss of intrinsic striatal dopaminergic input. |
1991-04-16 |
2023-08-11 |
rat |
| T S Rao, J A Cler, S J Mick, V M Dilworth, P C Contreras, S Iyengar, P L Woo. Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:1963476. |
irreversible inactivation of dopamine receptors by eedq (n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline) did not affect the opipramol-induced increases in levels of dihydroxyphenylacetic acid (dopac) in the striatum of the rat, indicating a predominant role of activation of sigma receptors in the dopaminergic effects of opipramol. |
1991-04-09 |
2023-08-11 |
mouse |
| K Ostergaard, J P Schou, J Zimme. Rat ventral mesencephalon grown as organotypic slice cultures and co-cultured with striatum, hippocampus, and cerebellum. Experimental brain research. vol 82. issue 3. 1991-04-09. PMID:1981356. |
tissue slices of rat ventral mesencephalon (vm), striatum, hippocampus and cerebellum were prepared from late fetal (e21) to 7 day old (p7) rats and cultured for 3 to 60 days by the roller tube technique before they were stained immunocytochemically for tyrosine hydroxylase (th), a marker of dopaminergic (da) neurons and fibres. |
1991-04-09 |
2023-08-11 |
rat |
| A Vaccari, E Stefanini, G de Montis, Z L Rossett. Dopaminergic dysfunction in neonatal hypothyroidism: differential effects of GM1 ganglioside. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:2149873. |
the ganglioside-driven selective recovery of the transport and storage process of [3h]dopamine might result either from a chronically-exerted stimulation by gm1 on the na/k- and mg-atpase activities, thus reflecting on the atpase-dependent neuronal and vesicular transport processes of dopamine or from a gm1-promoted maturation of the otherwise retarded functionality of dopaminergic nerve endings in the neonatal hypothyroid striatum. |
1991-04-09 |
2023-08-11 |
rat |
| S L Dewey, J D Brodie, J S Fowler, R R MacGregor, D J Schlyer, P T King, D L Alexoff, N D Volkow, C Y Shiue, A P Wol. Positron emission tomography (PET) studies of dopaminergic/cholinergic interactions in the baboon brain. Synapse (New York, N.Y.). vol 6. issue 4. 1991-03-25. PMID:1981112. |
interactions between the dopaminergic d2 receptor system and the muscarinic cholinergic system in the corpus striatum of adult female baboons (papio anubis) were examined using positron emission tomography (pet) combined with [18f]n-methylspiroperidol [( 18f]nmsp) (to probe d2 receptor availability) and [n-11c-methyl]benztropine (to probe muscarinic cholinergic receptor availability). |
1991-03-25 |
2023-08-11 |
Not clear |
| S L Dewey, J D Brodie, J S Fowler, R R MacGregor, D J Schlyer, P T King, D L Alexoff, N D Volkow, C Y Shiue, A P Wol. Positron emission tomography (PET) studies of dopaminergic/cholinergic interactions in the baboon brain. Synapse (New York, N.Y.). vol 6. issue 4. 1991-03-25. PMID:1981112. |
pretreatment with unlabelled nmsp, a potent dopaminergic antagonist, reduced the incorporation of [n-11c-methyl]benztropine in all brain regions, with the greatest effect being in the corpus striatum greater than cortex greater than thalamus greater than cerebellum, but did not alter the rate of metabolism of the labelled benztropine in the plasma. |
1991-03-25 |
2023-08-11 |
Not clear |
| M Miele, M S Desole, P Enrico, E Miel. [Selective pharmacological changes of regional ascorbic acid metabolism in the brain]. La Clinica terapeutica. vol 134. issue 6. 1991-03-22. PMID:2149531. |
activation of postsynaptic dopaminergic receptors increases ascorbate oxidation in striatum, but not in hypothalamus. |
1991-03-22 |
2023-08-11 |
Not clear |
| J P Bolam, Y Smit. The GABA and substance P input to dopaminergic neurones in the substantia nigra of the rat. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:1704287. |
the results of the present study: (1) demonstrate that dopaminergic neurones in the substantia nigra receive symmetrical synaptic input from gabaergic and substance p-containing terminals, (2) show that a proportion of these terminals contain both substance p and gaba and (3) suggest that the major synaptic input to dopaminergic neurones is from gabaergic terminals and that a part of this innervation is derived from the striatum. |
1991-03-19 |
2023-08-11 |
rat |
| L T Weiss-Wunder, M F Chessele. Heterogeneous distribution of cytochrome oxidase activity in the rat substantia nigra: correlation with tyrosine hydroxylase and dynorphin immunoreactivities. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:1980845. |
in addition, the pattern of histochemical staining observed for coase activity was correlated with immunohistochemistry for tyrosine hydroxylase (a marker of dopaminergic neurons) and for dynorphin (a peptide present in afferents from the striatum). |
1991-03-19 |
2023-08-11 |
rat |
| M N Castel, A Boireau, P M Laduro. Effect of gamma-butyrolactone on the retrograde axonal transport of neurotensin in dopaminergic neurones. European journal of pharmacology. vol 186. issue 1. 1991-03-15. PMID:1704309. |
gamma-butyrolactone is a drug known to inhibit the flow of electrical impulses in dopaminergic neurones and to prevent dopamine release in the striatum. |
1991-03-15 |
2023-08-11 |
rat |
| K P Gudehithlu, A M Duchemin, G A Tejwani, N H Neff, M Hadjiconstantino. Preproenkephalin mRNA and methionine-enkephalin increase in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1899692. |
dopaminergic neurons that project to the striatum from the substantia nigra are thought to modulate methionine-enkephalin (met-enk) metabolism in the striatum. |
1991-03-15 |
2023-08-11 |
mouse |