| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Hadjiconstantinou, J G Fitkin, A Dalia, N H Nef. Epidermal growth factor enhances striatal dopaminergic parameters in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse. Journal of neurochemistry. vol 57. issue 2. 1991-08-21. PMID:1677029. |
intracerebroventricular infusion of epidermal growth factor (egf) into mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced degeneration of dopaminergic nigrostriatal neurons partially enhanced the content of dopamine (da) and 3,4-dihydroxyphenylacetic acid as well as the activity of tyrosine hydroxylase in the striatum. |
1991-08-21 |
2023-08-11 |
mouse |
| M S Desole, M Miele, G Esposito, P Enrico, G De Natale, E Miel. Analysis of the mechanism of d-amphetamine-and apomorphine-induced changes of ascorbic acid catabolism in discrete brain areas of the rat. Pharmacological research. vol 23. issue 3. 1991-08-15. PMID:2068053. |
it is concluded that aa catabolism can be activated in the rat striatum by a dopaminergic mechanism; in hypothalamus and in remaining brain, the aa catabolism activation appears rather to be a non-specific effect of the pharmacological manipulation. |
1991-08-15 |
2023-08-11 |
rat |
| W Mihatsch, H Russ, M Gerlach, P Riederer, H Przunte. Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations. Journal of neural transmission. Parkinson's disease and dementia section. vol 3. issue 1. 1991-08-14. PMID:1905937. |
additional daily systemic treatment of monkeys with the antioxidants ascorbic acid (100 mg/kg) and alpha-tocopherol (2,350 mg/kg) prior to, during and following administration of mptp does not prevent the loss of dopamine and serotonin in the striatum, suggesting that these antioxidants are unable to protect dopaminergic neurones against neurotoxicity of mptp. |
1991-08-14 |
2023-08-11 |
monkey |
| J Arita, R Hashimoto, F Kimur. The activity of catecholamine synthesis in the hypothalamus of female normotensive Wistar Kyoto and spontaneously hypertensive rats. Brain research. vol 543. issue 1. 1991-08-01. PMID:1905181. |
no strain difference was found in dopa accumulation in the corpus striatum, which represents the activity of nigrostriatal dopaminergic neurons. |
1991-08-01 |
2023-08-11 |
rat |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
dopaminergic grafts in the striatum reduce d1 but not d2 receptor-mediated rotation in 6-ohda-lesioned rats. |
1991-07-31 |
2023-08-11 |
rat |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
rats received fetal dopaminergic neuronal grafts in the striatum and/or substantia nigra ipsilateral to a 6-hydroxydopamine (6-ohda) lesion of the medial forebrain bundle (mfb). |
1991-07-31 |
2023-08-11 |
rat |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
dopaminergic grafts in the striatum substantially and significantly reduced turning elicited by the selective d1 agonist skf 38393, but did not reduce turning elicited by the selective d2 agonist ly 171555. |
1991-07-31 |
2023-08-11 |
rat |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
fetal dopaminergic grafts in the ipsilateral substantia nigra (sn) did not augment the decreases in turning produced by concomitant ipsilateral dopaminergic grafts in the striatum in response to skf 38393. |
1991-07-31 |
2023-08-11 |
rat |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
dopaminergic grafts in the sn increased, while dopaminergic grafts in the striatum or in striatum and sn decreased, the facilitatory effect of d-amphetamine on rotation elicited by subsequent injection of dopamine agonists. |
1991-07-31 |
2023-08-11 |
rat |
| E K Richfiel. Quantitative autoradiography of the dopamine uptake complex in rat brain using [3H]GBR 12935: binding characteristics. Brain research. vol 540. issue 1-2. 1991-07-31. PMID:1829013. |
lesioning of the dopaminergic median forebrain bundle resulted in a dramatic loss of the dopamine uptake complex in the striatum, nucleus accumbens, olfactory tubercle, and substantia nigra. |
1991-07-31 |
2023-08-11 |
rat |
| T M Dawson, V L Dawson, F H Gage, L J Fisher, M A Hunt, J K Wamsle. Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants. Brain research. vol 540. issue 1-2. 1991-07-31. PMID:1905173. |
the autoradiographic distribution and density of muscarinic receptors was studied in the neostriatum of rats with long-term unilateral 6-hydroxydopamine (6-ohda) lesions of the nigrostriatal dopaminergic pathway and in lesioned rats who had additionally received embryonic substantia nigra grafts in the dopamine denervated striatum. |
1991-07-31 |
2023-08-11 |
rat |
| J V Georgiev. Influences of diterpene sclareol glycol on some dopamine related behavior. General pharmacology. vol 22. issue 2. 1991-07-31. PMID:2055429. |
these results were discussed in the light of a possible interaction of sg with dopaminergic transmission (da autoreceptors and postsynaptic da receptors) at the level of the striatum and the nucleus accumbens. |
1991-07-31 |
2023-08-11 |
mouse |
| P Chan, L E DeLanney, I Irwin, J W Langston, D Di Mont. Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain. Journal of neurochemistry. vol 57. issue 1. 1991-07-23. PMID:2051170. |
furthermore, atp loss in the striatum was prevented by mazindol, a catecholamine uptake blocker, indicating a rather selective effect of mptp on the atp content of dopaminergic terminals. |
1991-07-23 |
2023-08-11 |
mouse |
| M Miele, M S Desole, P Enrico, G Esposito, G De Natale, E Miel. A dopaminergic mechanism mediates the d-amphetamine- and apomorphine-induced increase of ascorbic acid metabolism in the rat striatum. Pharmacological research. vol 22 Suppl 3. 1991-07-23. PMID:2097636. |
a dopaminergic mechanism mediates the d-amphetamine- and apomorphine-induced increase of ascorbic acid metabolism in the rat striatum. |
1991-07-23 |
2023-08-11 |
rat |
| P A Paskevich, H K Evans, V B Domesic. Morphological assessment of neuronal aggregates in the striatum of the rat. The Journal of comparative neurology. vol 305. issue 3. 1991-07-03. PMID:1709952. |
it is postulated that the cellular aggregates may represent the fundamental level of striatal organization and may be local modules for intrinsic information processing, modifying extrinsic data processed through the biochemical compartmentalization of the striatum imparted by striosomes, neuropeptides, and dopaminergic, thalamic and cortical afferents. |
1991-07-03 |
2023-08-11 |
rat |
| S J Augood, H Kiyama, R L Faull, P C Emso. Differential effects of acute dopaminergic D1 and D2 receptor antagonists on proneurotensin mRNA expression in rat striatum. Brain research. Molecular brain research. vol 9. issue 4. 1991-06-28. PMID:1645436. |
differential effects of acute dopaminergic d1 and d2 receptor antagonists on proneurotensin mrna expression in rat striatum. |
1991-06-28 |
2023-08-11 |
rat |
| R E Burke, J Kent, N Kenyon, A Karana. Unilateral hypoxic-ischemic injury in neonatal rat results in a persistent increase in the density of striatal tyrosine hydroxylase immunoperoxidase staining. Brain research. Developmental brain research. vol 58. issue 2. 1991-06-19. PMID:1709395. |
while the functional significance of these findings are unknown, they are compatible with a relative increase in the dopaminergic innervation of the hypoxia-ischemia injured striatum. |
1991-06-19 |
2023-08-11 |
rat |
| J Segovia, D M Armstrong, W C Benzing, P J Hornb. Striatal glutamic acid decarboxylase immunoreactivity is increased after dopaminergic deafferentation: densitometric analysis. Neuroscience letters. vol 122. issue 2. 1991-06-07. PMID:1674120. |
several lines of evidence suggest that dopamine exerts a chronic inhibitory action on gabaergic cells in the striatum, and striatal glutamic acid decarboxylase (gad) mrna levels are increased after ipsilateral dopaminergic denervation. |
1991-06-07 |
2023-08-11 |
Not clear |
| K Ostergaard, J P Schou, B H Gähwiler, J Zimme. Tyrosine hydroxylase immunoreactive neurons in organotypic slice cultures of the rat striatum and neocortex. Experimental brain research. vol 83. issue 2. 1991-05-31. PMID:1673660. |
in order to examine whether innervation by dopaminergic fibers would affect the expression of th-i neurons in the striatal slice cultures, co-cultures of ventral mesencephalon (vm) and striatum were prepared, but the ingrowth of th-i fibers from the vm did not alter the expression of th immunoreactivity by a subpopulation of striatal neurons. |
1991-05-31 |
2023-08-11 |
rat |
| J M Delfs, A E Kelle. The role of D1 and D2 dopamine receptors in oral stereotypy induced by dopaminergic stimulation of the ventrolateral striatum. Neuroscience. vol 39. issue 1. 1991-05-24. PMID:1982467. |
the role of d1 and d2 dopamine receptors in oral stereotypy induced by dopaminergic stimulation of the ventrolateral striatum. |
1991-05-24 |
2023-08-11 |
rat |