| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Gaggi, A M Giann. Effects of brain biogenic amines of repeated treatments with calcium antagonists. Japanese journal of pharmacology. vol 56. issue 1. 1991-10-03. PMID:1880984. |
the drug-induced changes, displaying regional specificity and differences according to the various compounds, suggested that: (a) serotonergic systems were activated, especially in fasted rats or after repeated treatment; (b) the dopaminergic system of the striatum was inhibited by nifedipine which did reduce the hva levels and the hva/da, as well as the dopac/da, ratio. |
1991-10-03 |
2023-08-11 |
rat |
| M S Desole, M Miele, P Enrico, G Esposito, L Fresu, G De Natale, E Miel. Investigations into the relationship between the dopaminergic system and ascorbic acid in rat striatum. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1881615. |
investigations into the relationship between the dopaminergic system and ascorbic acid in rat striatum. |
1991-09-30 |
2023-08-11 |
rat |
| Z S Herman, M Huzarska, K Kmieciak-Kolada, J Kowalsk. Chronic treatment with chlorpromazine, thioridazine or haloperidol increases striatal enkephalins and their release from rat brain. Psychopharmacology. vol 104. issue 1. 1991-09-30. PMID:1881995. |
it is concluded that: 1) chronic administration of neuroleptic drugs that block dopamine receptors increases the level and the release of striatal enkephalins; 2) the results support the hypothesis that activation of dopaminergic neurons tonically inhibits the synthesis of enkephalins in the striatum. |
1991-09-30 |
2023-08-11 |
rat |
| O Giorgi, M G Pibiri, E Ongini, M Trampus, G Biggi. The neutral endopeptidase-24.11 (enkephalinase) inhibitor, SCH 32615, increases dopamine metabolism in the nucleus accumbens of the rat. European journal of pharmacology. vol 196. issue 2. 1991-09-20. PMID:1874283. |
the present study was designed to assess whether sch 32615 is able to modify the activity of dopaminergic neurons as reflected by changes in the content of the major dopamine metabolite, dihydroxyphenylacetic acid (dopac), in three different areas of the rat brain: the nucleus accumbens, the striatum, and the prefrontal cortex. |
1991-09-20 |
2023-08-11 |
rat |
| P Aebischer, S R Winn, P A Tresco, C B Jaeger, L A Green. Transplantation of polymer encapsulated neurotransmitter secreting cells: effect of the encapsulation technique. Journal of biomechanical engineering. vol 113. issue 2. 1991-09-20. PMID:1875690. |
in the present study, we compared the ability of dopamine-secreting cells, encapsulated by 2 different methods, to reverse experimental parkinson's disease, a neurodegenerative disease characterized by motor disturbances due to a lack of dopamine within the striatum following degeneration of the dopaminergic nigro-striatal pathway. |
1991-09-20 |
2023-08-11 |
rat |
| M S Desole, M Miele, G Esposito, L Fresu, P Enrico, G De Natale, V Anania, E Miel. [Cadmium-induced changes in the activity of the dopaminergic and purinergic systems and in ascorbic acid catabolism in the rat striatum]. La Clinica terapeutica. vol 137. issue 4. 1991-09-18. PMID:1831089. |
[cadmium-induced changes in the activity of the dopaminergic and purinergic systems and in ascorbic acid catabolism in the rat striatum]. |
1991-09-18 |
2023-08-11 |
rat |
| M S Desole, M Miele, G Esposito, L Fresu, P Enrico, G De Natale, V Anania, E Miel. [Cadmium-induced changes in the activity of the dopaminergic and purinergic systems and in ascorbic acid catabolism in the rat striatum]. La Clinica terapeutica. vol 137. issue 4. 1991-09-18. PMID:1831089. |
it is concluded that cadmium, given systemically, reduces dopaminergic system activity in the rat striatum; such impairment occurs together with an increase of aa oxidation and of markers of purinergic system activity. |
1991-09-18 |
2023-08-11 |
rat |
| J R Wickens, M E Alexander, R Mille. Two dynamic modes of striatal function under dopaminergic-cholinergic control: simulation and analysis of a model. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1871678. |
the model offers insights into the control of striatal neurodynamics by gmaxk which establish closer links between dopaminergic actions in the striatum and the mechanism of parkinsonian rigidity. |
1991-09-16 |
2023-08-11 |
Not clear |
| D R Bull, M J Sheeha. Presynaptic regulation of electrically evoked dopamine overflow in nucleus accumbens: a pharmacological study using fast cyclic voltammetry in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 343. issue 3. 1991-09-12. PMID:1678139. |
the results show that the presynaptic receptors on dopaminergic nerve terminals are of the d2 type and apparently identical to those in the corpus striatum. |
1991-09-12 |
2023-08-11 |
rat |
| J K Wan. Presynaptic glutamate receptors modulate dopamine release from striatal synaptosomes. Journal of neurochemistry. vol 57. issue 3. 1991-09-04. PMID:1650394. |
thus, these presynaptic glutamate receptors, localized on dopaminergic terminals in the striatum, appear to be pharmacologically similar to both the nmda and the non-nmda postsynaptic receptors. |
1991-09-04 |
2023-08-11 |
Not clear |
| J J Soghomonian, M F Chessele. Lesions of the dopaminergic nigrostriatal pathway alter preprosomatostatin messenger RNA levels in the striatum, the entopeduncular nucleus and the lateral hypothalamus of the rat. Neuroscience. vol 42. issue 1. 1991-08-30. PMID:1677745. |
lesions of the dopaminergic nigrostriatal pathway alter preprosomatostatin messenger rna levels in the striatum, the entopeduncular nucleus and the lateral hypothalamus of the rat. |
1991-08-30 |
2023-08-11 |
rat |
| J J Soghomonian, M F Chessele. Lesions of the dopaminergic nigrostriatal pathway alter preprosomatostatin messenger RNA levels in the striatum, the entopeduncular nucleus and the lateral hypothalamus of the rat. Neuroscience. vol 42. issue 1. 1991-08-30. PMID:1677745. |
the distribution and level of labeling for the messenger rna encoding preprosomatostatin was studied in the striatum and entopeduncular nucleus of rats with and without a selective destruction of the dopaminergic nigrostriatal pathway. |
1991-08-30 |
2023-08-11 |
rat |
| I Date, S Y Felten, D L Felte. The nigrostriatal dopaminergic system in MPTP-treated mice shows more prominent recovery by syngeneic adrenal medullary graft than by allogeneic or xenogeneic graft. Brain research. vol 545. issue 1-2. 1991-08-30. PMID:1860045. |
following systemic injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), young (2-month-old) c57bl/6 mice show decreased dopaminergic (da) nigrostriatal fibers and da concentration in the striatum. |
1991-08-30 |
2023-08-11 |
mouse |
| F Benfenati, E M Pich, M Zoli, R Grimaldi, K Fuxe, L F Agnat. Changes in striatal mu and delta opioid receptors after transient forebrain ischemia: a quantitative autoradiographic study. Brain research. vol 546. issue 1. 1991-08-23. PMID:1649667. |
the impairment of both opioid receptor subtypes suggests that opiate systems, like dopaminergic systems, are involved in the neurochemical changes observed in the striatum after transient forebrain ischemia. |
1991-08-23 |
2023-08-11 |
rat |
| W J Smeet. Comparative aspects of the distribution of substance P and dopamine immunoreactivity in the substantia nigra of amniotes. Brain, behavior and evolution. vol 37. issue 3. 1991-08-22. PMID:1712657. |
in the present account, the relation between the descending, substance p (sp)-containing projection fibers from the striatum and the dopaminergic cell bodies in the midbrain tegmentum was investigated in several species of reptiles and the domestic chicken by means of antisera against sp and dopamine. |
1991-08-22 |
2023-08-11 |
chicken |
| M Hadjiconstantinou, J G Fitkin, A Dalia, N H Nef. Epidermal growth factor enhances striatal dopaminergic parameters in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mouse. Journal of neurochemistry. vol 57. issue 2. 1991-08-21. PMID:1677029. |
intracerebroventricular infusion of epidermal growth factor (egf) into mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced degeneration of dopaminergic nigrostriatal neurons partially enhanced the content of dopamine (da) and 3,4-dihydroxyphenylacetic acid as well as the activity of tyrosine hydroxylase in the striatum. |
1991-08-21 |
2023-08-11 |
mouse |
| M S Desole, M Miele, G Esposito, P Enrico, G De Natale, E Miel. Analysis of the mechanism of d-amphetamine-and apomorphine-induced changes of ascorbic acid catabolism in discrete brain areas of the rat. Pharmacological research. vol 23. issue 3. 1991-08-15. PMID:2068053. |
it is concluded that aa catabolism can be activated in the rat striatum by a dopaminergic mechanism; in hypothalamus and in remaining brain, the aa catabolism activation appears rather to be a non-specific effect of the pharmacological manipulation. |
1991-08-15 |
2023-08-11 |
rat |
| W Mihatsch, H Russ, M Gerlach, P Riederer, H Przunte. Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations. Journal of neural transmission. Parkinson's disease and dementia section. vol 3. issue 1. 1991-08-14. PMID:1905937. |
additional daily systemic treatment of monkeys with the antioxidants ascorbic acid (100 mg/kg) and alpha-tocopherol (2,350 mg/kg) prior to, during and following administration of mptp does not prevent the loss of dopamine and serotonin in the striatum, suggesting that these antioxidants are unable to protect dopaminergic neurones against neurotoxicity of mptp. |
1991-08-14 |
2023-08-11 |
monkey |
| J Arita, R Hashimoto, F Kimur. The activity of catecholamine synthesis in the hypothalamus of female normotensive Wistar Kyoto and spontaneously hypertensive rats. Brain research. vol 543. issue 1. 1991-08-01. PMID:1905181. |
no strain difference was found in dopa accumulation in the corpus striatum, which represents the activity of nigrostriatal dopaminergic neurons. |
1991-08-01 |
2023-08-11 |
rat |
| G S Robertson, A Fine, H A Robertso. Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats. Brain research. vol 539. issue 2. 1991-07-31. PMID:1675908. |
dopaminergic grafts in the striatum reduce d1 but not d2 receptor-mediated rotation in 6-ohda-lesioned rats. |
1991-07-31 |
2023-08-11 |
rat |