Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Savasta, F Mennicken, M Chritin, D N Abrous, C Feuerstein, M Le Moal, J P Herma. Intrastriatal dopamine-rich implants reverse the changes in dopamine D2 receptor densities caused by 6-hydroxydopamine lesion of the nigrostriatal pathway in rats: an autoradiographic study. Neuroscience. vol 46. issue 3. 1992-04-13. PMID:1532053. |
the normal distribution of d1 and d2 dopaminergic receptors in the rat striatum was similar to that described previously. |
1992-04-13 |
2023-08-11 |
rat |
M Savasta, F Mennicken, M Chritin, D N Abrous, C Feuerstein, M Le Moal, J P Herma. Intrastriatal dopamine-rich implants reverse the changes in dopamine D2 receptor densities caused by 6-hydroxydopamine lesion of the nigrostriatal pathway in rats: an autoradiographic study. Neuroscience. vol 46. issue 3. 1992-04-13. PMID:1532053. |
the implantation of embryonic dopaminergic neurons into the denervated striatum led to a slight decrease of d1 receptor densities and to a reversal of the lesion-induced increase of striatal dopaminergic d2 receptors six months later. |
1992-04-13 |
2023-08-11 |
rat |
M A Cenci, P Kalén, R J Mandel, K Wictorin, A Björklun. Dopaminergic transplants normalize amphetamine- and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum. Neuroscience. vol 46. issue 4. 1992-04-09. PMID:1347413. |
dopaminergic transplants normalize amphetamine- and apomorphine-induced fos expression in the 6-hydroxydopamine-lesioned striatum. |
1992-04-09 |
2023-08-11 |
rat |
M A Cenci, P Kalén, R J Mandel, K Wictorin, A Björklun. Dopaminergic transplants normalize amphetamine- and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum. Neuroscience. vol 46. issue 4. 1992-04-09. PMID:1347413. |
dopamine receptor-mediated fos protein expression in the striatum has been used to monitor dopamine receptor activation at the cellular level after dopaminergic denervation and reinnervation by fetal nigral transplants. |
1992-04-09 |
2023-08-11 |
rat |
M A Cenci, P Kalén, R J Mandel, K Wictorin, A Björklun. Dopaminergic transplants normalize amphetamine- and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum. Neuroscience. vol 46. issue 4. 1992-04-09. PMID:1347413. |
the pattern of striatal fos expression after systemic administration of either the dopamine receptor agonist, apomorphine, or the dopamine-releasing agent, amphetamine, was studied in rats which had received cell suspension grafts of fetal ventral mesencephalic neurons into the striatum after a complete 6-hydroxydopamine lesion of mesostriatal dopaminergic projection. |
1992-04-09 |
2023-08-11 |
rat |
G S Robertson, H C Fibige. Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1347406. |
destruction of mesotelencephalic dopaminergic neurons with 6-hydroxydopamine abolished the increase in fos expression in the nucleus accumbens and striatum produced by haloperidol and raclopride, and also blocked the clozapine-induced increase in the nucleus accumbens. |
1992-04-08 |
2023-08-11 |
Not clear |
J W Polli, M L Billingsley, R L Kincai. Expression of the calmodulin-dependent protein phosphatase, calcineurin, in rat brain: developmental patterns and the role of nigrostriatal innervation. Brain research. Developmental brain research. vol 63. issue 1-2. 1992-04-01. PMID:1665105. |
however, in striatum, dopaminergic innervation does not appear to affect cn levels. |
1992-04-01 |
2023-08-11 |
human |
J F Chen, B Weis. Ontogenetic expression of D2 dopamine receptor mRNA in rat corpus striatum. Brain research. Developmental brain research. vol 63. issue 1-2. 1992-04-01. PMID:1665109. |
these results suggest that the postnatal development of the d2r mrna in rat striatum correlates well with the ontogeny of the d2 dopamine receptor, that the developmental expression of the d2r mrna is highly associated with the maturation and differentiation of striatal neurons, and that the development of the d2r mrna in rat striatum, unlike that of proenkephalin mrna, can proceed even with reduced dopaminergic afferent input from the substantia nigra. |
1992-04-01 |
2023-08-11 |
rat |
J A Angul. Involvement of dopamine D1 and D2 receptors in the regulation of proenkephalin mRNA abundance in the striatum and accumbens of the rat brain. Journal of neurochemistry. vol 58. issue 3. 1992-03-13. PMID:1346626. |
the data demonstrate that acute treatment with dopaminergic d2 agonists and antagonists affects proenkephalin mrna abundance in the striatum and accumbens via a d2 receptor mechanism, consistent with the concept that d2 receptor function inhibits the synthesis of the mrna encoding the enkephalin peptides. |
1992-03-13 |
2023-08-11 |
rat |
H Nissbrandt, G Engberg, E Pilebla. The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 1. 1992-03-02. PMID:1663587. |
furthermore, a large part of the da taken up by the dopaminergic terminals in the striatum and in the limbic forebrain seems to be re-incorporated into the storage vesicles. |
1992-03-02 |
2023-08-11 |
rat |
S J Augood, H Kiyama, R L Faull, P C Emso. Dopaminergic D1 and D2 receptor antagonists decrease prosomatostatin mRNA expression in rat striatum. Neuroscience. vol 44. issue 1. 1992-02-21. PMID:1685231. |
dopaminergic d1 and d2 receptor antagonists decrease prosomatostatin mrna expression in rat striatum. |
1992-02-21 |
2023-08-11 |
rat |
L Rioux, D P Gaudin, C Gagnon, T Di Paolo, P J Bédar. Decrease of behavioral and biochemical denervation supersensitivity of rat striatum by nigral transplants. Neuroscience. vol 44. issue 1. 1992-02-21. PMID:1770999. |
the density of dopaminergic receptors in the striatum of grafted and lesioned rats was examined by autoradiography by means of in vitro binding with [3h]sch 23390 for d1 receptors and [3h] spiperone for d2 receptors. |
1992-02-21 |
2023-08-11 |
rat |
N Pages, M Orosco, G Fournier, C Rouch, A Hafi, A Gourch, E Comoy, C Bohuo. The effects of chronic administration of morphine on the levels of brain and adrenal catecholamines and neuropeptide Y in rats. General pharmacology. vol 22. issue 5. 1992-02-13. PMID:1761199. |
the well-recognized biochemical alterations (serotoninergic turnover increased in the hypothalamus, hippocampus and striatum; dopaminergic turnover increased in the striatum and cortex; adrenaline levels decreased in the adrenal glands) were observed. |
1992-02-13 |
2023-08-11 |
rat |
J A Angulo, H Coirini, M Ledoux, M Schumache. Regulation by dopaminergic neurotransmission of dopamine D2 mRNA and receptor levels in the striatum and nucleus accumbens of the rat. Brain research. Molecular brain research. vol 11. issue 2. 1992-02-06. PMID:1661813. |
regulation by dopaminergic neurotransmission of dopamine d2 mrna and receptor levels in the striatum and nucleus accumbens of the rat. |
1992-02-06 |
2023-08-11 |
rat |
M I Martinez-Mir, A Probst, J M Palacio. Adenosine A2 receptors: selective localization in the human basal ganglia and alterations with disease. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1835521. |
similar losses of a2 receptors were observed in the guinea-pig striatum after local application of quinolinic acid while lesioning of the dopaminergic neurons was without effect. |
1992-01-02 |
2023-08-11 |
human |
M A Granner, G F Woote. Neuroleptic malignant syndrome or parkinsonism hyperpyrexia syndrome. Seminars in neurology. vol 11. issue 3. 1991-12-26. PMID:1947485. |
nms is probably caused by the reduction of dopaminergic activity in the cns, mainly in the hypothalamus and striatum. |
1991-12-26 |
2023-08-11 |
Not clear |
A Levy, M J Stillman, T M Rauc. Cyclo (His-Pro), d-amphetamine and striatal dopamine: a microdialysis study. Brain research bulletin. vol 27. issue 1. 1991-12-23. PMID:1933425. |
extracellular levels of dopamine (da) and its metabolites (dopac and hva) were monitored in the striatum of rats using in vivo microdialysis, in an attempt to elucidate the mechanism of cyclo (his-pro) (histidyl-proline-diketopiperazine, chp) on dopaminergic activity. |
1991-12-23 |
2023-08-11 |
rat |
I Date, S Asari, A Nishimoto, D Felte. [Cografts of adrenal medulla and peripheral nerve in a mouse model of Parkinson's disease]. No shinkei geka. Neurological surgery. vol 19. issue 9. 1991-12-17. PMID:1944788. |
since transected peripheral nerve segments are known to produce nerve growth factor, we performed adrenal medullary grafts or cografts of adrenal medulla and sciatic nerve into the striatum of mptp-treated mice, and compared the survivability of grafted chromaffin cells and the recovery of intrinsic host dopaminergic fibers. |
1991-12-17 |
2023-08-11 |
mouse |
I Date, S Asari, A Nishimoto, D Felte. [Cografts of adrenal medulla and peripheral nerve in a mouse model of Parkinson's disease]. No shinkei geka. Neurological surgery. vol 19. issue 9. 1991-12-17. PMID:1944788. |
the degree of recovery of host intrinsic dopaminergic fibers was greater in younger host striatum than in older host striatum. |
1991-12-17 |
2023-08-11 |
mouse |
L S Carman, F H Gage, C W Shult. Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain research. vol 553. issue 2. 1991-12-13. PMID:1681983. |
recent work, largely carried out in primate models of parkinson's disease (pd), indicates that residual dopaminergic neurons in the midbrain and their axons to the nucleus accumbens and striatum can be stimulated to sprout collateral axons, reinnervate the striatum, and cause a behavioral recovery. |
1991-12-13 |
2023-08-11 |
human |