Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
C Geula, J T Slevi. Substantia nigra 6-hydroxydopamine lesions alter dopaminergic synaptic markers in the nucleus basalis magnocellularis and striatum of rats. Synapse (New York, N.Y.). vol 4. issue 3. 1990-02-20. PMID:2532792. |
substantia nigra 6-hydroxydopamine lesions alter dopaminergic synaptic markers in the nucleus basalis magnocellularis and striatum of rats. |
1990-02-20 |
2023-08-11 |
human |
C Geula, J T Slevi. Substantia nigra 6-hydroxydopamine lesions alter dopaminergic synaptic markers in the nucleus basalis magnocellularis and striatum of rats. Synapse (New York, N.Y.). vol 4. issue 3. 1990-02-20. PMID:2532792. |
recent findings have demonstrated the existence of dopaminergic (da) markers in the nbm of the human brain and a reduction of these markers in both the nbm and the striatum of patients suffering from alzheimer's disease (ad). |
1990-02-20 |
2023-08-11 |
human |
M Hadjiconstantinou, F Weihmuller, N H Nef. Treatment with GM1 ganglioside reverses dopamine D-2 receptor supersensitivity induced by the neurotoxin MPTP. European journal of pharmacology. vol 168. issue 2. 1990-02-15. PMID:2532603. |
treatment of mice with the neurotoxin mptp to destroy nigrostriatal dopaminergic neurons results in up-regulation of d-2 receptors in the striatum when studied after 30 days. |
1990-02-15 |
2023-08-11 |
mouse |
T Matsumoto, T P Obrenovitch, G S Sarna, L Symo. [Extracellular concentration of dopamine and dopamine metabolites in the rat striatum during cerebral ischemia and reperfusion]. No to shinkei = Brain and nerve. vol 41. issue 10. 1990-02-13. PMID:2605040. |
many data suggest that the presence of dopamine (da) is a prerequisite for the development of neuronal damage in the striatum; neural injury could be initiated by a massive release from dopaminergic nerve terminals during ischemia. |
1990-02-13 |
2023-08-11 |
rat |
I Angel, A Janowsky, S M Pau. The effects of serotonergic and dopaminergic lesions on sodium-sensitive [3H]mazindol binding in rat hypothalamus and corpus striatum. Brain research. vol 503. issue 2. 1990-02-12. PMID:2514010. |
the effects of serotonergic and dopaminergic lesions on sodium-sensitive [3h]mazindol binding in rat hypothalamus and corpus striatum. |
1990-02-12 |
2023-08-11 |
rat |
I Angel, A Janowsky, S M Pau. The effects of serotonergic and dopaminergic lesions on sodium-sensitive [3H]mazindol binding in rat hypothalamus and corpus striatum. Brain research. vol 503. issue 2. 1990-02-12. PMID:2514010. |
the sodium-stimulated binding sites appear to be located on dopaminergic terminals in the striatum, and in the hypothalamus, the sodium-inhibited sites appear to be regulated by serotonergic neuronal activity. |
1990-02-12 |
2023-08-11 |
rat |
J P Tassi. [Neurotensin, dopamine and mode of action of neuroleptics]. L'Encephale. vol 15. issue 5. 1990-01-22. PMID:2574102. |
first, we describe experiments showing that ascending dopaminergic pathways control the density of neurotensinergic binding sites in structures such as prefrontal cortex, nucleus accumbens and striatum. |
1990-01-22 |
2023-08-11 |
Not clear |
R G MacKenzie, M K Stachowiak, M J Zigmon. Dopaminergic inhibition of striatal acetylcholine release after 6-hydroxydopamine. European journal of pharmacology. vol 168. issue 1. 1990-01-11. PMID:2511032. |
these findings indicate that dopamine, acting at the dopamine d-2 receptor, normally exerts an inhibitory influence over acetylcholine release in striatum, that after partial injury the dopaminergic influence over acetylcholine release can recover with time, and that the recovery involves processes other than changes in the number of d-2 receptors. |
1990-01-11 |
2023-08-11 |
rat |
M A Arian. Long-term changes in striatal D1 dopamine receptor distribution after dopaminergic deafferentation. Neuroscience. vol 32. issue 1. 1990-01-08. PMID:2531300. |
the morphochemical disposition of the adenylate cyclase-linked dopamine receptor (d1 type) in the rat striatum has been assessed at various time points after a neurotoxic lesion of the dopaminergic afferent pathway to the caudate nucleus. |
1990-01-08 |
2023-08-11 |
rat |
D Herve, F Trovero, G Blanc, A M Thierry, J Glowinski, J P Tassi. Nondopaminergic prefrontocortical efferent fibers modulate D1 receptor denervation supersensitivity in specific regions of the rat striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 11. 1990-01-03. PMID:2479723. |
a unilateral injection of 6-ohda (6 microgram/1.5 microliter) was made into the fields of forel in order to estimate the effects of the destruction of ascending dopaminergic (da) pathways on the denervation supersensitivity of da d1 receptors in the rat striatum. |
1990-01-03 |
2023-08-11 |
rat |
K W Lang. Circling behavior in old rats after unilateral intranigral injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Life sciences. vol 45. issue 18. 1990-01-02. PMID:2531261. |
these results suggest that mptp exerts neurotoxic effects on the nigrostriatal dopaminergic system of old rats and produces supersensitive dopamine receptors in the ipsilateral denervated striatum. |
1990-01-02 |
2023-08-11 |
rat |
M M Schweri, A E Jacobson, R A Lessor, K C Ric. Metaphit inhibits dopamine transport and binding of [3H]methylphenidate, a proposed marker for the dopamine transport complex. Life sciences. vol 45. issue 18. 1990-01-02. PMID:2586226. |
differences in the behavior of metaphit and phencyclidine in these dopaminergic systems compared to their effects on the nmda receptor-linked phencyclidine receptor suggest that metaphit may be interacting with two distinct molecular sites in the rat striatum. |
1990-01-02 |
2023-08-11 |
rat |
J E Rubinstein, R J Hitzemann, C R Ashby, R Y Wan. Long-term treatment with antipsychotics does not alter the phosphoinositide response to muscarinic or D2 dopaminergic agonists in rat striatum. Brain research. vol 496. issue 1-2. 1989-12-21. PMID:2572294. |
long-term treatment with antipsychotics does not alter the phosphoinositide response to muscarinic or d2 dopaminergic agonists in rat striatum. |
1989-12-21 |
2023-08-11 |
rat |
J E Rubinstein, R J Hitzemann, C R Ashby, R Y Wan. Long-term treatment with antipsychotics does not alter the phosphoinositide response to muscarinic or D2 dopaminergic agonists in rat striatum. Brain research. vol 496. issue 1-2. 1989-12-21. PMID:2572294. |
the effects of the muscarinic agonist carbachol and the d2 dopaminergic agonist quinpirole on phosphoinositide hydrolysis were studied in the corpus striatum of rats which had been treated for one year with either haloperidol or clozapine. |
1989-12-21 |
2023-08-11 |
rat |
T Kita, T Nakashim. [Tolerance and reverse tolerance of nicotine on spontaneous motor activity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 94. issue 2. 1989-12-21. PMID:2680832. |
recently, neurochemical and behavioral studies have shown the possibility that reverse tolerance of nicotine on the spontaneous motor activity is probably concerned with the dopaminergic system through nicotinic acetylcholine receptors in the striatum or mesolimbic dopaminergic system of the rat brain. |
1989-12-21 |
2023-08-11 |
rat |
D C German, K Manaye, W K Smith, D J Woodward, C B Sape. Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Annals of neurology. vol 26. issue 4. 1989-11-30. PMID:2817827. |
these data suggest that parkinson's disease preferentially destroys midbrain dopaminergic neurons in nuclei a8, a9, and a10, which project to the striatum. |
1989-11-30 |
2023-08-11 |
human |
S A Zinn, K J Lookingland, H A Tucker, K E Moor. Alterations in concentrations of dihydroxyphenylacetic acid in the median eminence of rats euthanatized with pentobarbital. Laboratory animal science. vol 39. issue 5. 1989-11-27. PMID:2811280. |
in contrast, none of the manipulations altered da or dopac concentrations in the striatum, which contains terminals of nigrostriatal dopaminergic neurons. |
1989-11-27 |
2023-08-11 |
rat |
P R Lowenstein, P A Slesinger, H S Singer, L C Walker, M F Casanova, L S Raskin, D L Price, J T Coyl. Compartment-specific changes in the density of choline and dopamine uptake sites and muscarinic and dopaminergic receptors during the development of the baboon striatum: a quantitative receptor autoradiographic study. The Journal of comparative neurology. vol 288. issue 3. 1989-11-22. PMID:2794143. |
compartment-specific changes in the density of choline and dopamine uptake sites and muscarinic and dopaminergic receptors during the development of the baboon striatum: a quantitative receptor autoradiographic study. |
1989-11-22 |
2023-08-11 |
Not clear |
Z Elazar, G Siegel, S Fuch. Association of two pertussis toxin-sensitive G-proteins with the D2-dopamine receptor from bovine striatum. The EMBO journal. vol 8. issue 8. 1989-11-09. PMID:2571500. |
the solubilized d2-dopamine receptor from bovine striatum exhibits high and low affinity states for dopaminergic agonists. |
1989-11-09 |
2023-08-11 |
cattle |
G S Robertson, H A Robertso. Evidence that L-dopa-induced rotational behavior is dependent on both striatal and nigral mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 9. issue 9. 1989-11-07. PMID:2795165. |
this is accompanied by a loss of dopamine in brain regions, such as the corpus striatum, which receives input from dopaminergic neurons in the substantia nigra (sn). |
1989-11-07 |
2023-08-11 |
rat |