| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Morelli, S Fenu, A Pinna, G Di Chiar. Adenosine A2 receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats. European journal of pharmacology. vol 251. issue 1. 1994-04-28. PMID:7907985. |
quinolinic acid lesion of the striatum or 6-hydroxydopamine lesion of the dopaminergic nigro-striatal neurons demonstrated that [3h]cgs 21680 binding sites are associated to striatal intrinsic neurons. |
1994-04-28 |
2023-08-12 |
rat |
| M Poncelet, C Gueudet, D Gully, P Soubrié, G Le Fu. Turning behavior induced by intrastriatal injection of neurotensin in mice: sensitivity to non-peptide neurotensin antagonists. Naunyn-Schmiedeberg's archives of pharmacology. vol 349. issue 1. 1994-04-28. PMID:8139701. |
the intrastriatal injection of neurotensin (10 pg/mouse) elicited vigorous contralateral rotations which were not affected by disruption of dopaminergic transmission using 6-ohda lesion of the striatum or systemic administration of spiroperidol (0.03 mg/kg). |
1994-04-28 |
2023-08-12 |
mouse |
| C J Schmidt, C K Sullivan, G M Fadaye. Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine. Journal of neurochemistry. vol 62. issue 4. 1994-04-20. PMID:7907650. |
in contrast, infusion of mdl 100,907 into the mid-brain region near the dopaminergic cell bodies was without effect on the mdma-induced elevation of extracellular dopamine in the ipsilateral striatum. |
1994-04-20 |
2023-08-12 |
rat |
| M A Cenci, K Campbell, A Björklun. Neuropeptide messenger RNA expression in the 6-hydroxydopamine-lesioned rat striatum reinnervated by fetal dopaminergic transplants: differential effects of the grafts on preproenkephalin, preprotachykinin and prodynorphin messenger RNA levels. Neuroscience. vol 57. issue 2. 1994-03-29. PMID:8115038. |
neuropeptide messenger rna expression in the 6-hydroxydopamine-lesioned rat striatum reinnervated by fetal dopaminergic transplants: differential effects of the grafts on preproenkephalin, preprotachykinin and prodynorphin messenger rna levels. |
1994-03-29 |
2023-08-12 |
rat |
| K Ikawa, A Watanabe, S Kaneno, M Tor. Modulation of [3H]mazindol binding sites in rat striatum by dopaminergic agents. European journal of pharmacology. vol 250. issue 2. 1994-03-25. PMID:7906653. |
modulation of [3h]mazindol binding sites in rat striatum by dopaminergic agents. |
1994-03-25 |
2023-08-12 |
rat |
| M Navarro, F Rodríguez de Fonseca, M L Hernández, J A Ramos, J J Fernández-Rui. Motor behavior and nigrostriatal dopaminergic activity in adult rats perinatally exposed to cannabinoids. Pharmacology, biochemistry, and behavior. vol 47. issue 1. 1994-03-25. PMID:7906890. |
in the second experiment, we evaluated neurochemical indices--dopamine (da) and l-3,4-dihydroxyphenylacetic acid (dopac) contents, tyrosine hydroxylase (th) activity, and number and affinity of d1 and d2 dopaminergic receptors in the striatum--and behavioral parameters--spontaneous locomotor activity and spontaneous and induced stereotypic behavior--both indicating nigrostriatal dopaminergic activity, in adult female and male rats perinatally exposed to hashish extract. |
1994-03-25 |
2023-08-12 |
rat |
| F Rodríguez de Fonseca, M A Gorriti, J J Fernández-Ruiz, T Palomo, J A Ramo. Downregulation of rat brain cannabinoid binding sites after chronic delta 9-tetrahydrocannabinol treatment. Pharmacology, biochemistry, and behavior. vol 47. issue 1. 1994-03-25. PMID:8115426. |
this tolerance was accompanied by significant decreases in the density of cannabinoid receptors in the striatum and limbic forebrain, the areas where nerve terminals for nigrostriatal and mesolimbic dopaminergic systems, respectively, which play an important role in those processes, are located. |
1994-03-25 |
2023-08-12 |
rat |
| P Pollak, A L Benabid, P Limousin, C L Gervason, E Jeanneau-Nicoll. External and implanted pumps for apomorphine infusion in parkinsonism. Acta neurochirurgica. Supplementum. vol 58. 1994-03-24. PMID:8109301. |
continuous delivery of dopaminergic agents to the striatum is a major challenge to improve the treatment of parkinson's disease. |
1994-03-24 |
2023-08-12 |
monkey |
| C W Shults, R T Matthews, C A Altar, L R Hill, P J Langlai. A single intramesencephalic injection of brain-derived neurotrophic factor induces persistent rotational asymmetry in rats. Experimental neurology. vol 125. issue 2. 1994-03-23. PMID:8313937. |
levels of dopamine in the striatum and number of dopaminergic neurons in the snpc were similar in bdnf- and vehicle-treated animals. |
1994-03-23 |
2023-08-12 |
rat |
| C Malapani, B Pillon, B Dubois, Y Agi. Impaired simultaneous cognitive task performance in Parkinson's disease: a dopamine-related dysfunction. Neurology. vol 44. issue 2. 1994-03-17. PMID:8309583. |
these results suggest that adequate dopaminergic transmission is necessary for concurrent processing of cognitive information and that the striatum integrates the sensorimotor information required to program cognitive acts. |
1994-03-17 |
2023-08-12 |
Not clear |
| R Simanto. Chronic morphine alters dopamine transporter density in the rat brain: possible role in the mechanism of drug addiction. Neuroscience letters. vol 163. issue 2. 1994-03-17. PMID:8309616. |
it is suggested, therefore, that chronic morphine treatment has a long-lasting and selective effect on the activity of dopamine transporters in the dopaminergic reward pathway, but not in the striatum. |
1994-03-17 |
2023-08-12 |
rat |
| Y P Maneuf, I J Mitchell, A R Crossman, J M Brotchi. On the role of enkephalin cotransmission in the GABAergic striatal efferents to the globus pallidus. Experimental neurology. vol 125. issue 1. 1994-03-16. PMID:8307125. |
in the mptp-treated primate model of parkinson's disease, loss of dopaminergic afferents to the striatum leads to increased activity in striatal efferents to the external segment of the globus pallidus. |
1994-03-16 |
2023-08-12 |
rat |
| M N Castel, A Beaudet, P M Laduro. Retrograde axonal transport of neurotensin in rat nigrostriatal dopaminergic neurons. Modulation during ageing and possible physiological role. Biochemical pharmacology. vol 47. issue 1. 1994-03-15. PMID:7906122. |
neurotensin receptors are mainly located in the striatum on nerve terminals of the nigrostriatal dopaminergic pathway. |
1994-03-15 |
2023-08-12 |
rat |
| M Lembreghts, M Anssea. [Biological markers in schizophrenia]. L'Encephale. vol 19. issue 5. 1994-03-14. PMID:8306920. |
the dopaminergic hypothesis of schizophrenia reposes on the major following facts: the therapeutic efficiency of neuroleptics (dopaminergic antagonists); a positive correlation between plasma homovanillic acid (metabolite of dopamine) concentration and the severity of schizophrenic illness; a higher density of dopaminergic d2-receptors (revealed by positron emission tomography thanks to specific radioligands), particularly in the striatum; and an abnormal plasmatic growth-hormone response to apomorphine (dopaminergic agonist). |
1994-03-14 |
2023-08-12 |
Not clear |
| E S Vizi, I E Tóth, E Orsó, K S Szalay, D Szabó, M Baranyi, G P Vinso. Dopamine is taken up from the circulation by, and released from, local noradrenergic varicose axon terminals in zona glomerulosa of the rat: a neurochemical and immunocytochemical study. The Journal of endocrinology. vol 139. issue 2. 1994-03-11. PMID:8308458. |
da-containing nerves were not seen in the adrenal cortex; however, the same immunocytochemical procedures clearly demonstrated dopaminergic nerve cells and fibres in the substantia nigra and the striatum respectively, and cells of the adrenal medulla. |
1994-03-11 |
2023-08-12 |
human |
| T G Nygaard, K C Wilhelmsen, N J Risch, D L Brown, J M Trugman, T C Gilliam, S Fahn, D E Week. Linkage mapping of dopa-responsive dystonia (DRD) to chromosome 14q. Nature genetics. vol 5. issue 4. 1994-03-10. PMID:8298648. |
pathological evidence suggests that this may be due to the establishment of a reduced number of dopaminergic nerve terminals in the striatum, or to an excessive reduction (pruning) of these terminals in early development. |
1994-03-10 |
2023-08-12 |
Not clear |
| N Hashimoto, T Matsumoto, H Mabe, T Hashitani, H Nishin. Dopamine has inhibitory and accelerating effects on ischemia-induced neuronal cell damage in the rat striatum. Brain research bulletin. vol 33. issue 3. 1994-03-03. PMID:7904889. |
dopaminergic (daergic) influence on ischemic neuronal cell damage in the dorsolateral striatum was studied. |
1994-03-03 |
2023-08-12 |
rat |
| Z H Qin, J F Chen, B Weis. Lesions of mouse striatum induced by 6-hydroxydopamine differentially alter the density, rate of synthesis, and level of gene expression of D1 and D2 dopamine receptors. Journal of neurochemistry. vol 62. issue 2. 1994-03-02. PMID:8294904. |
these results suggest that dopaminergic denervation differentially affects the rate of synthesis of d1 and d2 dopamine receptors in mouse striatum, and that these alterations in the rates of synthesis of the receptors may be explained by corresponding alterations in the levels of the respective transcripts for these receptors. |
1994-03-02 |
2023-08-12 |
mouse |
| J Zhou, I Date, K Sakai, Y Yoshimoto, T Furuta, S Asari, T Ohmot. Xenogeneic dopaminergic grafts reverse behavioral deficits induced by 6-OHDA in rodents: effect of 15-deoxyspergualin treatment. Neuroscience letters. vol 163. issue 1. 1994-03-02. PMID:8295740. |
foetal rat mesencephalic dopamine-containing tissue was transplanted into the lateral ventricle of mice previously subjected to a 6-ohda lesion of dopaminergic nerve terminals in the corpus striatum. |
1994-03-02 |
2023-08-12 |
mouse |
| A F Yakimovskii, I V Karpov. The influence of chronic activation and blockade of the dopamine- and enkephalinergic systems of the neostriatum on conditioned reflex behavior and dopamine metabolism in the rat nigrostriatal system. Neuroscience and behavioral physiology. vol 23. issue 6. 1994-02-24. PMID:8290027. |
the chronic stimulation of the dopaminergic system of the striatum induced facilitation of the realization of an active avoidance conditioned reflex, and stimulated exploratory stereotypy, while its blockade led to suppression of conditioned reflex activity against the background of a clearcut rigid akinetic syndrome. |
1994-02-24 |
2023-08-12 |
rat |