Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R Rodríguez-Puertas, A Pazos, J Pascua. Cholinergic markers in degenerative parkinsonism: autoradiographic demonstration of high-affinity choline uptake carrier hyperactivity. Brain research. vol 636. issue 2. 1994-07-26. PMID:8012816. |
these data demonstrate a hyperactivity of the hacu, and thus of the acetylcholine synthesis, in parkinsonian brains probably compensatory of the loss of both dopaminergic terminals in the striatum and of basal forebrain neurons in the hippocampus. |
1994-07-26 |
2023-08-12 |
Not clear |
E Lynd-Balta, S N Habe. The organization of midbrain projections to the striatum in the primate: sensorimotor-related striatum versus ventral striatum. Neuroscience. vol 59. issue 3. 1994-07-21. PMID:7516506. |
thus, the dopaminergic regulation of the sensorimotor-related striatum and the ventral striatum may be different. |
1994-07-21 |
2023-08-12 |
Not clear |
G S Robertson, W A Staine. D1 dopamine receptor agonist-induced Fos-like immunoreactivity occurs in basal forebrain and mesopontine tegmentum cholinergic neurons and striatal neurons immunoreactive for neuropeptide Y. Neuroscience. vol 59. issue 2. 1994-07-21. PMID:7911982. |
in vivo microdialysis studies indicate that cholinergic interneurons in the striatum are excited by the administration of cy 208-243 and that this effect is potentiated by dopaminergic deafferentation. |
1994-07-21 |
2023-08-12 |
Not clear |
W Maruyama, M Nao. Inhibition of tyrosine hydroxylase by a dopamine neurotoxin, 1-methyl-4-phenylpyridinium ion: depletion of allostery to the biopterin cofactor. Life sciences. vol 55. issue 3. 1994-07-19. PMID:7911964. |
the effect of a dopaminergic neurotoxin, 1-methyl-4-phenylpyridinium ion (mpp+) on the activity of tyrosine hydroxylase was examined using the enzyme sample prepared from the rat striatum. |
1994-07-19 |
2023-08-12 |
human |
A S Undie, E Friedma. Inhibition of dopamine agonist-induced phosphoinositide hydrolysis by concomitant stimulation of cyclic AMP formation in brain slices. Journal of neurochemistry. vol 63. issue 1. 1994-07-11. PMID:7911510. |
the interaction between dopamine d1 receptor-stimulated elevations in cyclic amp and dopaminergic stimulation of inositol phosphate formation suggests a cellular colocalization of these dopamine-coupled transduction pathways in at least some cells of the rat striatum. |
1994-07-11 |
2023-08-12 |
rat |
S R Wachtel, E D Abercrombi. L-3,4-dihydroxyphenylalanine-induced dopamine release in the striatum of intact and 6-hydroxydopamine-treated rats: differential effects of monoamine oxidase A and B inhibitors. Journal of neurochemistry. vol 63. issue 1. 1994-07-11. PMID:8207420. |
to assess the role of dopaminergic nerve terminals in determining the effects of exogenous l-dopa on extracellular dopamine levels in striatum, we examined the relative contributions of monoamine oxidase a and monoamine oxidase b to the catabolism of dopamine synthesized from exogenous l-dopa. |
1994-07-11 |
2023-08-12 |
rat |
J T Greenamyre, R V Eller, Z Zhang, A Ovadia, R Kurlan, D M Gas. Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease. Annals of neurology. vol 35. issue 6. 1994-07-08. PMID:8210221. |
loss of dopaminergic innervation of the striatum results in overactivity of the glutamatergic pathways from the subthalamic nucleus to the internal segment of the globus pallidus and the substantia nigra pars reticulata, the output nuclei of the basal ganglia. |
1994-07-08 |
2023-08-12 |
rat |
K Unsicke. Growth factors in Parkinson's disease. Progress in growth factor research. vol 5. issue 1. 1994-07-07. PMID:8199355. |
several molecules, most of which occur in the striatum and the substantia nigra, have been identified that protect lesioned dopaminergic nigrostriatal neurons in culture or in animal models of parkinson's disease. |
1994-07-07 |
2023-08-12 |
human |
A Pastuszk. Metabolic responses of the dopaminergic system during hypoxia in newborn brain. Biochemical medicine and metabolic biology. vol 51. issue 1. 1994-06-28. PMID:8192912. |
these changes in the dopaminergic system may contribute directly and indirectly to the neuronal damage that occurs during hypoxic/ischemic insult and reoxygenation in newborn brain, particularly in the striatum. |
1994-06-28 |
2023-08-12 |
Not clear |
F A Mendelsohn, T A Jenkins, S F Berkovi. Effects of angiotensin II on dopamine and serotonin turnover in the striatum of conscious rats. Brain research. vol 613. issue 2. 1994-06-21. PMID:7514480. |
this study was designed to evaluate the functional significance of angiotensin ii (ang ii) receptors identified by previous receptor autoradiography studies to be located presynaptically on terminals of dopaminergic neurones projecting to the striatum. |
1994-06-21 |
2023-08-12 |
rat |
P Chan, D A Di Monte, J J Luo, L E DeLanney, I Irwin, J W Langsto. Rapid ATP loss caused by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity. Journal of neurochemistry. vol 62. issue 6. 1994-06-21. PMID:8189253. |
rapid atp loss caused by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity. |
1994-06-21 |
2023-08-12 |
mouse |
B Deleplanque, S Vitiello, M Le Moal, P J Neve. Modulation of immune reactivity by unilateral striatal and mesolimbic dopaminergic lesions. Neuroscience letters. vol 166. issue 2. 1994-06-09. PMID:8177502. |
lymphocyte proliferation as well as natural killer (nk) cell activity were analysed in mice, 2 weeks after unilateral lesions of dopaminergic projections by in situ injection of 6-hydroxydopamine in the striatum or the nucleus accumbens. |
1994-06-09 |
2023-08-12 |
mouse |
W J Free. Glutamatergic mechanisms mediating stimulant and antipsychotic drug effects. Neuroscience and biobehavioral reviews. vol 18. issue 1. 1994-06-01. PMID:7909593. |
decreased activity at dopaminergic synapses, as produced by neuroleptic drugs, causes changes in the activation of cortically derived synapses in the corpus striatum and nucleus accumbens which result in behavioral sedation and decreased activity. |
1994-06-01 |
2023-08-12 |
Not clear |
S Goto, S Nagahiro, K Korematsu, K Kogo, Y Ushi. Subdivisional ischemic injury of the unilateral striatum causes apomorphine-induced rotational behavior in rats. Acta neuropathologica. vol 87. issue 2. 1994-06-01. PMID:8171972. |
histologically, the ipsilateral striatum of the rats showed a subdivisional ischemic injury, while the nigral dopaminergic neurons appeared intact. |
1994-06-01 |
2023-08-12 |
rat |
A Calignano, P Persico, F Mancuso, L Sorrentin. L-arginine modulates morphine-induced changes in locomotion in mice. Annali dell'Istituto superiore di sanita. vol 29. issue 3. 1994-06-01. PMID:8172459. |
in mice opioids increase dopaminergic turnover in nucleus striatum and nucleus accumbens, causing behavioural changes such as increased locomotion. |
1994-06-01 |
2023-08-12 |
mouse |
K Suyama, K H Dykstra, M I Masana, H K Manji, W Z Potte. In vivo evidence that nonneuronal beta-adrenoceptors as well as dopamine receptors contribute to cyclic AMP efflux in rat striatum. Journal of neurochemistry. vol 62. issue 5. 1994-05-18. PMID:8158123. |
we applied in vivo microdialysis to assess the effects of dopaminergic and beta-adrenergic receptor stimulation on cyclic amp efflux in rat striatum under chloral hydrate anesthesia. |
1994-05-18 |
2023-08-12 |
rat |
G H Tjon, T J De Vries, E Ronken, F Hogenboom, G Wardeh, A H Mulder, A N Schoffelmee. Repeated and chronic morphine administration causes differential long-lasting changes in dopaminergic neurotransmission in rat striatum without changing its delta- and kappa-opioid receptor regulation. European journal of pharmacology. vol 252. issue 2. 1994-05-13. PMID:7908881. |
repeated and chronic morphine administration causes differential long-lasting changes in dopaminergic neurotransmission in rat striatum without changing its delta- and kappa-opioid receptor regulation. |
1994-05-13 |
2023-08-12 |
rat |
G H Tjon, T J De Vries, E Ronken, F Hogenboom, G Wardeh, A H Mulder, A N Schoffelmee. Repeated and chronic morphine administration causes differential long-lasting changes in dopaminergic neurotransmission in rat striatum without changing its delta- and kappa-opioid receptor regulation. European journal of pharmacology. vol 252. issue 2. 1994-05-13. PMID:7908881. |
these data indicate that, long after cessation of drug treatment, chronic morphine treatment causes a reduction whereas repeated morphine administration gradually induces an enhancement of opioid receptor-regulated dopaminergic neurotransmission due to local adaptive changes within the rat striatum. |
1994-05-13 |
2023-08-12 |
rat |
J M Schumacher, P Hantraye, A L Brownell, D Riche, B K Madras, P D Davenport, M Maziere, D R Elmaleh, G L Brownell, O Isacso. A primate model of Huntington's disease: functional neural transplantation and CT-guided stereotactic procedures. Cell transplantation. vol 1. issue 4. 1994-05-12. PMID:1344304. |
2) high-resolution positron emission tomography (pet) can be used to image the decreased glucose utilization and the preservation of dopaminergic terminals in the lesioned striatum by using 2-fluoro-deoxy-d-glucose (2fdg) and n-(c-11)-methyl-2-beta-carbomethoxy-3-beta-phenyl tropane (cpt) as tracers. |
1994-05-12 |
2023-08-11 |
Not clear |
M A Hynes, K Poulsen, M Armanini, L Berkemeier, H Phillips, A Rosentha. Neurotrophin-4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures. Journal of neuroscience research. vol 37. issue 1. 1994-05-04. PMID:7908342. |
a common pathology in parkinson's patients is degeneration of substantia nigra dopaminergic neurons that innervate the striatum and a corresponding decrease in striatal dopamine content. |
1994-05-04 |
2023-08-12 |
rat |