Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
P A Frohna, D S Rothblat, J N Joyce, J S Schneide. Alterations in dopamine uptake sites and D1 and D2 receptors in cats symptomatic for and recovered from experimental parkinsonism. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709343. |
the administration of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to adult cats severely disrupts the dopaminergic innervation of the striatum. |
1995-05-09 |
2023-08-12 |
Not clear |
J W Francis, J Von Visger, G J Markelonis, T H O. Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum. Neurotoxicology and teratology. vol 17. issue 1. 1995-05-05. PMID:7535890. |
neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum. |
1995-05-05 |
2023-08-12 |
mouse |
J W Francis, J Von Visger, G J Markelonis, T H O. Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum. Neurotoxicology and teratology. vol 17. issue 1. 1995-05-05. PMID:7535890. |
we have studied the reactive responses of both astrocytes and microglia to dopaminergic denervation of the striatum by mptp. |
1995-05-05 |
2023-08-12 |
mouse |
A Boireau, P Dubédat, F Bordier, C Peny, J M Miquet, G Durand, M Meunier, A Dobl. Riluzole and experimental parkinsonism: antagonism of MPTP-induced decrease in central dopamine levels in mice. Neuroreport. vol 5. issue 18. 1995-05-04. PMID:7696626. |
we have investigated whether riluzole, a compound that interferes with glutamatergic (gluergic) transmission, would protect central dopaminergic (daergic) neurones from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced toxicity in the striatum in mice. |
1995-05-04 |
2023-08-12 |
mouse |
N Koshikaw. Role of the nucleus accumbens and the striatum in the production of turning behaviour in intact rats. Reviews in the neurosciences. vol 5. issue 4. 1995-05-04. PMID:7697201. |
however, the assumption that asymmetrical activation of the striatum is a necessary condition for dopamine-dependent turning behaviour has been questioned by several studies showing that unilateral injection of amphetamine or dopamine receptor agonists into the nucleus accumbens, a target of the mesolimbic dopaminergic system, also produces reliable circling away from the side of injection. |
1995-05-04 |
2023-08-12 |
rat |
C Ffrench-Constant, G A Mathew. Brain repair: lessons from developmental biology. Journal of neurology. vol 242. issue 1 Suppl 1. 1995-05-03. PMID:7699405. |
promising initial results have emerged with transplantation for the very focal defect of parkinson's disease, using fetal dopaminergic neurons placed directly into the denervated striatum. |
1995-05-03 |
2023-08-12 |
human |
H Sershen, A Hashim, A Lajth. Effect of ibogaine on serotonergic and dopaminergic interactions in striatum from mice and rats. Neurochemical research. vol 19. issue 11. 1995-04-26. PMID:7898613. |
effect of ibogaine on serotonergic and dopaminergic interactions in striatum from mice and rats. |
1995-04-26 |
2023-08-12 |
mouse |
G Nikkhah, M Olsson, J Eberhard, C Bentlage, M G Cunningham, A Björklun. A microtransplantation approach for cell suspension grafting in the rat Parkinson model: a detailed account of the methodology. Neuroscience. vol 63. issue 1. 1995-04-25. PMID:7898661. |
spreading of dopaminergic micrografts over multiple small deposits rather than increasing the volume of single grafts gave more extensive reinnervation of the entire host striatum. |
1995-04-25 |
2023-08-12 |
rat |
H Moukhles, M Amalric, A Nieoullon, A Daszut. Behavioural recovery of rats grafted with dopamine cells after partial striatal dopaminergic depletion in a conditioned reaction-time task. Neuroscience. vol 63. issue 1. 1995-04-25. PMID:7898663. |
in the present model for partial dopamine depletion of the striatum, the mechanisms underlying the graft-induced recovery probably involve the participation of endogenous dopamine neurons acting in addition to, and/or in synergy with the dopamine-rich grafted tissue so that a functional level of dopaminergic transmission is restored in transplanted animals. |
1995-04-25 |
2023-08-12 |
rat |
E C Hirsc. Biochemistry of Parkinson's disease with special reference to the dopaminergic systems. Molecular neurobiology. vol 9. issue 1-3. 1995-04-18. PMID:7888089. |
the cardinal neurochemical abnormality in parkinson's disease is the decreased dopamine content in the striatum, resulting from the loss of dopaminergic neurons in the mesencephalon. |
1995-04-18 |
2023-08-12 |
Not clear |
F C Liu, H Takahashi, R D McKay, A M Graybie. Dopaminergic regulation of transcription factor expression in organotypic cultures of developing striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 2. 1995-04-17. PMID:7891173. |
dopaminergic regulation of transcription factor expression in organotypic cultures of developing striatum. |
1995-04-17 |
2023-08-12 |
rat |
F C Liu, H Takahashi, R D McKay, A M Graybie. Dopaminergic regulation of transcription factor expression in organotypic cultures of developing striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 2. 1995-04-17. PMID:7891173. |
to test for the functional responsiveness of developing striatal neurons to dopaminergic stimulation, we established an organotypic slice culture of newborn rat striatum. |
1995-04-17 |
2023-08-12 |
rat |
H Onoe, O Inoue, K Suzuki, H Tsukada, T Itoh, N Mataga, Y Watanab. Ketamine increases the striatal N-[11C]methylspiperone binding in vivo: positron emission tomography study using conscious rhesus monkey. Brain research. vol 663. issue 2. 1995-04-06. PMID:7874501. |
these results indicate that ketamine facilitates striatal dopaminergic neurotransmission through increasing the binding activity of dopamine d2 receptors in the striatum, and suggest that these changes may be related to the psychotomimetic behavioral symptoms of this drug. |
1995-04-06 |
2023-08-12 |
monkey |
M C Asselin, J J Soghomonian, P Y Côté, A Paren. Striatal changes in preproenkephalin mRNA levels in parkinsonian monkeys. Neuroreport. vol 5. issue 16. 1995-03-30. PMID:7865763. |
the other striatal sectors, including the caudate nucleus, did not exhibit significant changes, despite the fact that the loss of the dopaminergic input was severe in most of the striatum. |
1995-03-30 |
2023-08-12 |
monkey |
Y Ichitani, H Okamura, D Nakahara, I Nagatsu, Y Ibat. Biochemical and immunocytochemical changes induced by intrastriatal 6-hydroxydopamine injection in the rat nigrostriatal dopamine neuron system: evidence for cell death in the substantia nigra. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867756. |
the results showed that degeneration of the dopaminergic terminals in the striatum may lead to cell death of the parent cell bodies in the sn and suggest that the striatum may be the initial site in which the neurodegeneration occurs in parkinson's disease. |
1995-03-27 |
2023-08-12 |
rat |
M Okad. [Effects of carbamazepine and zonisamide on dopaminergic system in rat striatum and hippocampus]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 14. issue 5. 1995-03-15. PMID:7856330. |
[effects of carbamazepine and zonisamide on dopaminergic system in rat striatum and hippocampus]. |
1995-03-15 |
2023-08-12 |
rat |
P Anglade, S Tsuji, F Javoy-Agid, Y Agid, E C Hirsc. Plasticity of nerve afferents to nigrostriatal neurons in Parkinson's disease. Annals of neurology. vol 37. issue 2. 1995-03-07. PMID:7847868. |
clinical symptoms in parkinson's disease do not appear until almost total depletion of dopamine has occurred in the striatum, suggesting the existence of compensatory mechanisms to offset the loss of nigrostriatal dopaminergic neurons. |
1995-03-07 |
2023-08-12 |
human |
R Karler, L D Calder, L H Thai, J B Bedingfiel. A dopaminergic-glutamatergic basis for the action of amphetamine and cocaine. Brain research. vol 658. issue 1-2. 1995-03-02. PMID:7834358. |
the data suggest that stereotypy induced by amphetamine or cocaine is mediated by a dopaminergic activation of a glutamatergic system within the striatum. |
1995-03-02 |
2023-08-12 |
mouse |
I Date, Y Miyoshi, T Imaoka, T Furuta, S Asari, T Ohmot. Efficacy of pretransection of peripheral nerve for promoting the survival of cografted chromaffin cells and recovery of host dopaminergic fibers in animal models of Parkinson's disease. Neuroscience research. vol 20. issue 3. 1995-03-02. PMID:7838422. |
we performed adrenal medullary alone grafts or cografts of adrenal medulla and acutely transected or pretransected (24 h before) sciatic nerve into the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-treated mice, and compared the survival of chromaffin cells and the recovery of the host-intrinsic dopaminergic fibers using tyrosine hydroxylase immunocytochemistry and high-performance liquid chromatography. |
1995-03-02 |
2023-08-12 |
mouse |
R Kötte. Postsynaptic integration of glutamatergic and dopaminergic signals in the striatum. Progress in neurobiology. vol 44. issue 2. 1995-02-17. PMID:7831476. |
postsynaptic integration of glutamatergic and dopaminergic signals in the striatum. |
1995-02-17 |
2023-08-12 |
Not clear |