Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
P Salin, A Nieoullon, L Kerkerian-Le Gof. Reversal of the adaptive response of neuropeptide Y neurons in the rat striatum to nigrostriatal dopamine deafferentation by the N-methyl-D-aspartate antagonist dizocilpine maleate. Neuroscience. vol 61. issue 1. 1994-11-28. PMID:7969899. |
this study examined the effects of systemic treatments with dizocilpine maleate alone or in combination with unilateral 6-hydroxydopamine-induced lesion of the nigrostriatal dopaminergic neurons on the number and staining intensity of neuropeptide y-immunoreactive neurons in the rat striatum. |
1994-11-28 |
2023-08-12 |
rat |
P Salin, A Nieoullon, L Kerkerian-Le Gof. Reversal of the adaptive response of neuropeptide Y neurons in the rat striatum to nigrostriatal dopamine deafferentation by the N-methyl-D-aspartate antagonist dizocilpine maleate. Neuroscience. vol 61. issue 1. 1994-11-28. PMID:7969899. |
as reported previously, the unilateral dopaminergic lesion elicited an increase in both the number and staining intensity of neuropeptide y-immunoreactive neurons in the ipsilateral striatum. |
1994-11-28 |
2023-08-12 |
rat |
G M Gonzalez-Alvear, L L Werlin. Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands. The Journal of pharmacology and experimental therapeutics. vol 271. issue 1. 1994-11-25. PMID:7965717. |
sigma receptors have been located in several areas of the brain that control motor function, including on the dopaminergic projections from substantia nigra to striatum. |
1994-11-25 |
2023-08-12 |
rat |
I Sziráki, V Kardos, M Patthy, M Pátfalusi, J Gaál, M Solti, E Kollár, J Singe. Amphetamine-metabolites of deprenyl involved in protection against neurotoxicity induced by MPTP and 2'-methyl-MPTP. Journal of neural transmission. Supplementum. vol 41. 1994-11-23. PMID:7931228. |
post-treatment by 1-deprenyl, 1-methamphetamine, 1-amphetamine (at times when mptp is no longer present in the striatum of mice) protects against neurotoxicity in c57bl mice by blocking the uptake of mpp+ into dopaminergic neurons, and even against the neurotoxicity induced by 2'ch3-mptp, which is partly bioactivated by mao-a. |
1994-11-23 |
2023-08-12 |
mouse |
S Gobaille, C Schmidt, A Cupo, F Herbrecht, M Maitr. Characterization of methionine-enkephalin release in the rat striatum by in vivo dialysis: effects of gamma-hydroxybutyrate on cellular and extracellular methionine-enkephalin levels. Neuroscience. vol 60. issue 3. 1994-11-17. PMID:7936191. |
gamma-hydroxybutyrate occurs endogenously in the mammalian brain, and is most probably involved in the regulation of some basic brain functions, particularly those concerning the dopaminergic nigrostriatal pathway, which is closely linked to the expression of enkephalins in the striatum. |
1994-11-17 |
2023-08-12 |
rat |
J J Soghomonian, S Pedneault, G Audet, A Paren. Increased glutamate decarboxylase mRNA levels in the striatum and pallidum of MPTP-treated primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 10. 1994-11-14. PMID:7931578. |
the dopaminergic innervation, as visualized and quantified on x-ray films after 3h-mazindol binding on tissue sections, was uniformly lost throughout the striatum of mptp-treated monkeys. |
1994-11-14 |
2023-08-12 |
monkey |
F Trovero, P Marin, J P Tassin, J Premont, J Glowinsk. Accelerated resensitization of the D1 dopamine receptor-mediated response in cultured cortical and striatal neurons from the rat: respective role of alpha 1-adrenergic and N-methyl-D-aspartate receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 10. 1994-11-14. PMID:7931580. |
as previously shown in vivo, noradrenergic and glutamatergic neurons can regulate the denervation supersensitivity of d1 dopaminergic (da) receptors in the rat prefrontal cortex and striatum respectively. |
1994-11-14 |
2023-08-12 |
rat |
D G Cole, L A Kobierski, C Konradi, S E Hyma. 6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 20. 1994-10-27. PMID:7937819. |
because expression of the c-fos gene in response to camp- and ca2+/calmodulin-regulated protein kinases depends on phosphorylation of camp-response element-binding protein (creb) at ser-133, we examined creb phosphorylation after dopaminergic stimulation in cultured striatal neurons and in the striatum of rats after unilateral 6-hydroxydopamine ablation of the substantia nigra. |
1994-10-27 |
2023-08-12 |
rat |
T Reum, R Morgenster. Fetal mesencephalic grafts influence the dopamine release in the non-lesioned striatum of 6-OHDA-lesioned rats: a behavioral and in vivo voltammetric study. Neuroscience letters. vol 173. issue 1-2. 1994-10-25. PMID:7936408. |
these results show clearly that unilateral fetal mesencephalic grafts producing behavioural recovery in the unilateral 6-ohda model of the rat produce changes at dopaminergic mechanisms in the non-lesioned striatum. |
1994-10-25 |
2023-08-12 |
rat |
J M Henselmans, F G Wouterloo. Light and electron microscopic characterization of cholinergic and dopaminergic structures in the striatal complex and the dorsal ventricular ridge of the lizard Gekko gecko. The Journal of comparative neurology. vol 345. issue 1. 1994-10-18. PMID:7916354. |
the study is part of a large research program in which the cholinergic and dopaminergic elements of the striatum of rats and reptiles are studied at morphological and neurochemical levels. |
1994-10-18 |
2023-08-12 |
rat |
J M Henselmans, F G Wouterloo. Light and electron microscopic characterization of cholinergic and dopaminergic structures in the striatal complex and the dorsal ventricular ridge of the lizard Gekko gecko. The Journal of comparative neurology. vol 345. issue 1. 1994-10-18. PMID:7916354. |
in conclusion, we found little evidence for the presence of synaptic interaction between the cholinergic and dopaminergic systems in the striatum of this reptile. |
1994-10-18 |
2023-08-12 |
rat |
E R Larson, M A Arian. Dopamine receptor binding on identified striatonigral neurons. Neuroscience letters. vol 172. issue 1-2. 1994-10-11. PMID:8084509. |
determining the specific cellular location for these dopamine receptors in the striatum is important to the design of drug treatments for disorders with suspected dopaminergic involvement such as parkinson's disease. |
1994-10-11 |
2023-08-12 |
Not clear |
D Otto, K Unsicke. FGF-2 in the MPTP model of Parkinson's disease: effects on astroglial cells. Glia. vol 11. issue 1. 1994-09-29. PMID:8070894. |
administration of 4 micrograms of either fgf-2 or cyt c (soaked into a piece of gelfoam unilaterally to the right striatum in either mptp- or saline-injected controls) increased striatal gfap levels bilaterally about 2- to 2.5-fold at 14 days, when fgf-2 showed marked protection of dopaminergic parameters. |
1994-09-29 |
2023-08-12 |
mouse |
Y Wang, S D Wang, S Z Lin, J C Li. Restoration of dopamine overflow and clearance from the 6-hydroxydopamine lesioned rat striatum reinnervated by fetal mesencephalic grafts. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:7915321. |
the purpose of these experiments was to investigate the electrochemical indices of mesencephalic dopaminergic grafts as they function in the rat striatum. |
1994-09-28 |
2023-08-12 |
rat |
J P O'Callaghan, D B Mille. Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071867. |
dopaminergic (da) and serotonergic (5-ht) projections to striatum and cortex have been implicated as the primary targets of substituted amphetamine (amp)-induced neurotoxicity, largely on the basis of the propensity of these compounds to cause protracted decrements in da and 5-ht rather than on the basis of amp-induced alterations of indices linked to neural damage. |
1994-09-28 |
2023-08-12 |
mouse |
D B Miller, J P O'Callagha. Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071868. |
in the companion paper we demonstrated that d-methamphetamine (d-meth), d-methylenedioxyamphetamine (d-mda) and d-methylenedioxymethamephetamine (d-mdma), but not d-fenfluramine (d-fen), appear to damage dopaminergic projections to the striatum of the mouse. |
1994-09-28 |
2023-08-12 |
mouse |
G Torres, C Rivie. Induction of c-fos in rat brain by acute cocaine and fenfluramine exposure: a comparison study. Brain research. vol 647. issue 1. 1994-09-26. PMID:8069690. |
although cocaine shares the ability of fenfluramine to inhibit the synaptic reuptake of serotonin, previous observations from our group suggest that the genomic effects of fenfluramine in the rat striatum are primarily mediated by dopaminergic rather than serotonergic mechanisms. |
1994-09-26 |
2023-08-12 |
rat |
Y Smith, B D Bennett, J P Bolam, A Parent, A F Sadiko. Synaptic relationships between dopaminergic afferents and cortical or thalamic input in the sensorimotor territory of the striatum in monkey. The Journal of comparative neurology. vol 344. issue 1. 1994-09-22. PMID:7914894. |
synaptic relationships between dopaminergic afferents and cortical or thalamic input in the sensorimotor territory of the striatum in monkey. |
1994-09-22 |
2023-08-12 |
monkey |
Y Smith, B D Bennett, J P Bolam, A Parent, A F Sadiko. Synaptic relationships between dopaminergic afferents and cortical or thalamic input in the sensorimotor territory of the striatum in monkey. The Journal of comparative neurology. vol 344. issue 1. 1994-09-22. PMID:7914894. |
the aim of the present study was to determine the synaptic relationships between cortical or thalamic inputs and the dopaminergic afferents in the sensorimotor territory of the monkey striatum. |
1994-09-22 |
2023-08-12 |
monkey |
Y Smith, B D Bennett, J P Bolam, A Parent, A F Sadiko. Synaptic relationships between dopaminergic afferents and cortical or thalamic input in the sensorimotor territory of the striatum in monkey. The Journal of comparative neurology. vol 344. issue 1. 1994-09-22. PMID:7914894. |
these findings suggest that the dopaminergic afferents are located to subserve a more specific modulation of afferent cortical input than afferent thalamic input in the sensorimotor territory of the striatum in primates. |
1994-09-22 |
2023-08-12 |
monkey |